povidone-iodine and Cicatrix

Establishing continuity of the cutaneous roll is critical to cleft lip repair. Unfortunately, this landmark can be difficult to appreciate depending on the patient's skin tone, surgical lighting, or preexisting scar.. When applied to the lip, dilute povidone-iodine solution beads off the cutaneous roll and dry vermilion, clearly defining these structures.. We use dilute povidone-iodine solution not only to prep the lip but to delineate landmarks critical to cleft lip repair.

Topics: Cicatrix; Cleft Lip; Humans; Plastic Surgery Procedures; Povidone-Iodine; Surgical Flaps

Electrostimulation of wounds caused healing to proceed in a thoroughly organized manner. A trial using rats subjected to second degree burns was conducted to evaluate, under scanning electron microscopy (SEM), the healing capabilities of skin to which an antiseptic (iodine) and referred electrical stimulation were applied. Untreated, unharmed skin was also studied as control. Images obtained using SEM revealed that only the repaired skin of the electrostimulated group had an appearance similar to that of the control skin (kappa = 1), and that the overall appearance of the repaired skin was compatible with a well organized healing process.

Topics: Animals; Burns; Cicatrix; Electric Stimulation Therapy; Infections; Male; Microscopy, Electron, Scanning; Povidone-Iodine; Rats; Rats, Sprague-Dawley; Wound Healing

The present study was designed to test the hypothesis that povidone-iodine would inhibit the recovery of tensile strength in a healing wound. Clean, incised dorsal wounds in rats were soaked in 1% povidone-iodine solution for 15 minutes; control wounds were soaked in lactated Ringer's solution before closure. Tensile strength measurements and histologic studies were conducted at 1, 2, and 6 weeks. No statistical differences in the rate of gain of tensile strength or histological appearance were noted between control and experimental wounds. It is concluded that brief irrigation of clean incised wounds with povidone-iodine solution does not affect factors important in the recovery of tensile strength during would healing, such as fibroplasia and collagen cross-linking.

Topics: Animals; Cicatrix; Male; Povidone; Povidone-Iodine; Rats; Tensile Strength; Wound Healing; Wound Infection