potassium-permanganate and Stomach-Ulcer

With the purpose of improvement of diagnosis of induced gastric ulcer were examined 11 patients who took aggressive agents for simulation of gastric ulcer and 33 patients who took pseudo-aggressive agents. Observables, conduced diagnosis of local chemical burn of mucous coat of stomach during initial 6 days after taking aggressive agents. Stages of ulcerous process, resulting from local chemical burn of mucous coat of stomach, coressponds to real gactric ulcer. Gelatin capsule using as a container for delivery of aggressive agents, melts in stomach in 5-6 minutes after taking. Independent from body position, mucous coat of greater curvature of the stomach is damaged. It is impossible to simulate duodenal bulb ulcer using the gelatine capsule or ball made of breadcrumb. The last method of delivery of aggressive agent can damage the small intestine because of uncontrollability of the place of breaking the ball.

Topics: Adolescent; Anti-Ulcer Agents; Burns, Chemical; Chlorine Compounds; Diagnosis, Differential; Endoscopy, Digestive System; Gastric Mucosa; Humans; Male; Military Personnel; Potassium Permanganate; Stomach Ulcer; Time Factors; Ultrasonography

In this work, the authors are concerned with the study of the effects of non-steroidal antiinflammatory drugs in the gastric mucosa of the rat after induced chronic inflammation with potassium permanganate.

Topics: Animals; Diflunisal; Drug Interactions; Gastric Mucosa; Indomethacin; Male; Potassium Permanganate; Rats; Salicylates; Stomach Ulcer