potassium-permanganate and Skin-Ulcer

Two patients with cutaneous alternaria infection are presented. In both patients the skin lesions were characterized by multiple non-healing ulcers covered with dry crusts. Although the skin changes were macroscopically alike in the two patients, differences in the histology were seen. Both patients had primary debilitating diseases. A review of the literature is presented and revealed an additional ten cases of cutaneous alternariosis. Methods for the isolation of Alternaria and the susceptibility of the fungus to antimycotic drugs are presented.

Topics: Adolescent; Adult; Alternaria; Amphotericin B; Child, Preschool; Chlorquinaldol; Dermatomycoses; Female; Flucytosine; Gentian Violet; Griseofulvin; Humans; Male; Middle Aged; Mitosporic Fungi; Nystatin; Potassium Permanganate; Skin Ulcer

Topics: Aged, 80 and over; Dermatologic Agents; Diagnosis, Differential; Disease Progression; Hand Dermatoses; Humans; Male; Pain; Potassium Permanganate; Skin Ulcer; Treatment Outcome

A 73-year-old female patient presented with acute very painful perianal ulcerations. She reported using various ointments and later potassium permanganate baths because of maceration of the rima ani as a manifestation of her psoriasis vulgaris. Suddenly after starting the potassium permanganate baths, necrotic areas developed with then became ulcerated. After excluding the relevant differential diagnostic considerations, we diagnosed ulcerations caused by a caustic burn from potassium permanganate. After stooping potassium permanganate baths and employing modern moist wound therapy, we attained complete healing after 8 months of treatment.

Topics: Acute Disease; Aged; Baths; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Potassium Permanganate; Proctitis; Skin Ulcer

Topics: Anti-Bacterial Agents; Colitis, Ulcerative; Gangrene; Humans; Potassium Permanganate; Prednisolone; Pyoderma; Skin Ulcer