potassium-permanganate and Poisoning

This case of an unintentional ingestion of an unknown amount of potassium permanganate by a 5-year-old boy, and its sequelae, exemplifies the potential danger of this poison. Due to the wide availability of this agent in over-the-counter preparations and the high potential for serious sequelae, clinicians should be aware of the actions of this agent, as well as the diagnostic and management features associated with it.

Topics: Anti-Ulcer Agents; Burns, Chemical; Caustics; Child, Preschool; Emergencies; Endoscopy, Digestive System; Esophagitis; Gastritis; Humans; Male; Poisoning; Potassium Permanganate; Ranitidine; Ulcer

Topics: Aluminum Compounds; Burns, Chemical; Humans; Phosphines; Poisoning; Potassium Permanganate

Topics: Administration, Oral; Aluminum Compounds; Antidotes; Charcoal; Drug Administration Schedule; Health Knowledge, Attitudes, Practice; Humans; Molecular Weight; Phosphines; Poisoning; Potassium Permanganate; Treatment Outcome

Aluminum phosphide (AlP) is used as a fumigant. It produces phosphine gas, which is a mitochondrial poison. Unfortunately, there is no known antidote for AlP intoxication, and also, there are few data about its prognostic factors.. The aim of this study was to determine the impact of the Simplified Acute Physiology Score II (SAPS II ) in the prediction of outcome in patients with acute AlP poisoning requiring admission to the Intensive Care Unit (ICU).. This was a prospective study in patients with acute AlP poisoning, admitted to the ICU over a period of 12 months. The demographic data were collected and SAPSII was recorded. The patients were divided into survival and non-survival groups due to outcome.. The data were expressed as mean ± SD for continuous or discrete variables and as frequency and percentage for categorical variables. The results were compared between the two groups using SPSS software. Results : During the study period, 39 subjects were admitted to the ICU with acute AlP poisoning. All 39 patients required endotracheal intubation and mechanical ventilation in addition to gastric decontamination with sodium bicarbonate, permanganate potassium, and activated charcoal, therapy with MgSO 4 and calcium gluconate and adequate hydration. Among these patients, 26 (66.7%) died. SAPSII was significantly higher in the non-survival group than in the survival group (11.88 ± 4.22 vs. 4.31 ± 2.06, respectively) (P < 0.001).. SAPSII calculated within the first 24 hours was recognized as a good prognostic indicator among patients with acute AlP poisoning requiring ICU admission.

Topics: Adolescent; Adult; Aluminum Compounds; Antidotes; Charcoal; Female; Forecasting; Humans; Male; Middle Aged; Pesticides; Phosphines; Poisoning; Potassium Permanganate; Prospective Studies; Severity of Illness Index; Sodium Bicarbonate; Treatment Outcome; Young Adult

Topics: Anti-Infective Agents, Local; Bronchoscopy; Caustics; Child, Preschool; Coloring Agents; Communication Barriers; Endoscopy, Digestive System; Humans; Language; Laryngeal Edema; Male; Oxidants; Poisoning; Potassium Permanganate; Russia

Topics: Antidotes; Ascorbic Acid; First Aid; Humans; Poisoning; Potassium Permanganate

Potassium permanganate intoxication in 3 infant girls (2.5, 2.5 and 5 months old, respectively) is described. In 2 the toxic solution was mistaken for a vitamin A+D preparation due to package similarity. The main clinical symptoms included restlessness, low grade fever and inflamed oral mucosa with black-brown discoloration. There was leukocytosis with a shift to the left. Complications described by others, such as hepatic and renal damage, upper air-way obstruction, gastrointestinal ulceration, bleeding tendency, methemoglobinemia and hemolysis, were not seen in our infants. Management included hemodynamic and respiratory monitoring, oral and gastric water lavage and milk ingestion. Laboratory follow-up included CBC and hepatic and renal function tests. There were no complications, and follow-up revealed no residual abnormalities.

Topics: Animals; Female; Follow-Up Studies; Gastric Lavage; Humans; Infant; Leukocytosis; Medication Errors; Milk; Monitoring, Physiologic; Poisoning; Potassium Permanganate

Two cases of acute acquired methaemoglobinaemia following the ingestion of witch doctor's preparations, are presented. Chemical analysis of the ingested powder revealed a mixture of soot and potassium permanganate. Both patients were comatose and deeply cyanosed but the response to oxygen, methylene blue and vitamin C was good.

Topics: Adult; Female; Humans; Intensive Care Units; Medicine, Traditional; Methemoglobinemia; Oxygen; Poisoning; Potassium Permanganate; South Africa

Topics: Burns, Chemical; Catheterization; Gastric Mucosa; Humans; Laryngoscopy; Poisoning; Potassium Permanganate; Radiography; Stomach; Tablets; Thiosulfates

Topics: Acute Disease; Adolescent; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Laparotomy; Poisoning; Potassium Permanganate

Topics: Humans; Hydralazine; Manganese Compounds; Mercury; Mercury Poisoning; Oxides; Petroleum; Poisoning; Potassium Permanganate; Tranylcypromine

Topics: Child; Humans; Infant; Ions; Manganese; Poisoning; Potassium; Potassium Permanganate