potassium-permanganate and Neoplasms

Topics: Carbon; Chlorine; Chlorine Compounds; Chloroform; Disinfectants; Disinfection; Female; Flocculation; Humans; Ion Exchange Resins; Male; Neoplasms; Oxides; Ozone; Potassium Permanganate; Safety; Sterilization; Urinary Bladder Neoplasms; Water Microbiology; Water Supply

Transition-metal dichalcogenides (TMDCs) have attracted a lot of attention due to their electronic, optical, mechanical, and catalytic properties. In addition, TMDCs possess rich redox chemistry that enables the decoration of metal nanoparticles directly on their surfaces. In this paper, MnO2/MoS2 nanocomplexes were obtained by the spontaneous reduction of KMnO4 with MoS2 QDs as the reductive agent. The formed MnO2/MoS2 nanocomplexes exhibited activated fluorescence and MR imaging signal in the presence of glutathione (GSH). After conjugation with an AS1411 aptamer, specific in vivo MR imaging and fluorescence labeling of the 786-O tumor cells were realized, showing their promising potential for biomedical applications.

Topics: Animals; Aptamers, Nucleotide; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Disulfides; Glutathione; Humans; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Molybdenum; Neoplasms; Oxidation-Reduction; Potassium Permanganate; Quantum Dots

Congo red screening of 27,052 routine biopsy specimens from 22,827 patients over a 5 1/2-year period in the Department of Pathology, University of Malaya detected 186 cases of amyloidosis. The categories of amyloidosis encountered and their prevalences in relation to each other were: systemic AL (5.9%); systemic AA (3.2%); isolated atrial (14%); primary localized cutaneous (7.5%); other primary localized deposits (3.2%); localized intratumour (58%); and dystrophic (8.6%). A third of patients with systemic AL amyloidosis had coexistent immunocyte abnormality. The commonest underlying pathology for systemic AA amyloidosis was leprosy. Notable among the types of localized amyloidosis revealed by this study were isolated atrial amyloidosis, which appeared to complicate chronic rheumatic heart disease, and intratumour amyloidosis complicating nasopharyngeal carcinoma. Other tumours in which amyloid deposits were observed included basal cell carcinoma, islet cell tumour and medullary carcinoma of the thyroid. Dystrophic amyloidosis was observed in fibrotic tissues, such as damaged cardiac valves and osteoarthritic joints. Heredofamilial amyloidosis, senile systemic amyloidosis and degenerative cerebral amyloidosis were notably absent from this study.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyloid; Amyloidosis; Cardiomyopathies; Child; Humans; Immunoglobulin kappa-Chains; Immunoglobulin lambda-Chains; Immunohistochemistry; Malaysia; Microscopy, Electron; Middle Aged; Neoplasms; Potassium Permanganate; Prevalence; Skin Diseases

Topics: Adult; Aged; Chromatography, Ion Exchange; Creatinine; Cytarabine; Diatrizoate; Female; Folic Acid; Heparin; Humans; Hydrogen-Ion Concentration; Male; Methods; Methotrexate; Middle Aged; Neoplasms; Oxidation-Reduction; Potassium Permanganate; Spectrometry, Fluorescence; Time Factors; Triamterene; Tritium; Tryptophan; Tungsten

Oral potassium permanganate has been used in the management of terminal carcinoma in three patients. Symptomatic improvement occurred in all three, with elimination of oral foetor in one patient and diminished requirement of analgesics in the other two. The mental state of each patient was improved and normal activities were resumed.

Topics: Aged; Carcinoma, Squamous Cell; Female; Humans; Liver Neoplasms; Male; Middle Aged; Mouth Neoplasms; Neoplasms; Palliative Care; Pancreatic Neoplasms; Potassium Permanganate; Terminal Care

Topics: Electrons; Histological Techniques; Microscopy; Microscopy, Electron; Neoplasms; Potassium Permanganate; Viruses