potassium-permanganate and Burns--Chemical

Potassium permanganate (KMnO

Topics: Burns, Chemical; Dermatology; Humans; Potassium Permanganate; Skin; Wound Healing

This case of an unintentional ingestion of an unknown amount of potassium permanganate by a 5-year-old boy, and its sequelae, exemplifies the potential danger of this poison. Due to the wide availability of this agent in over-the-counter preparations and the high potential for serious sequelae, clinicians should be aware of the actions of this agent, as well as the diagnostic and management features associated with it.

Topics: Anti-Ulcer Agents; Burns, Chemical; Caustics; Child, Preschool; Emergencies; Endoscopy, Digestive System; Esophagitis; Gastritis; Humans; Male; Poisoning; Potassium Permanganate; Ranitidine; Ulcer

With the purpose of improvement of diagnosis of induced gastric ulcer were examined 11 patients who took aggressive agents for simulation of gastric ulcer and 33 patients who took pseudo-aggressive agents. Observables, conduced diagnosis of local chemical burn of mucous coat of stomach during initial 6 days after taking aggressive agents. Stages of ulcerous process, resulting from local chemical burn of mucous coat of stomach, coressponds to real gactric ulcer. Gelatin capsule using as a container for delivery of aggressive agents, melts in stomach in 5-6 minutes after taking. Independent from body position, mucous coat of greater curvature of the stomach is damaged. It is impossible to simulate duodenal bulb ulcer using the gelatine capsule or ball made of breadcrumb. The last method of delivery of aggressive agent can damage the small intestine because of uncontrollability of the place of breaking the ball.

Topics: Adolescent; Anti-Ulcer Agents; Burns, Chemical; Chlorine Compounds; Diagnosis, Differential; Endoscopy, Digestive System; Gastric Mucosa; Humans; Male; Military Personnel; Potassium Permanganate; Stomach Ulcer; Time Factors; Ultrasonography

Topics: Accidents, Home; Burns, Chemical; Capsules; Esophagoscopy; Esophagus; Female; Gastric Fundus; Gastroscopy; Humans; Middle Aged; Potassium Permanganate

Topics: Amnion; Burns, Chemical; Child; Critical Care; Eye Burns; Female; Humans; Potassium Permanganate; Prosthesis Implantation; Transplantation, Homologous; Treatment Outcome

Topics: Aluminum Compounds; Burns, Chemical; Humans; Phosphines; Poisoning; Potassium Permanganate

Topics: Adult; Burns, Chemical; Caustics; Humans; Male; Potassium Permanganate; Stomach

Topics: Anti-Infective Agents, Local; Burns, Chemical; Dermatitis, Atopic; Humans; Infant; Male; Potassium Permanganate; Tablets

Topics: Burns, Chemical; Child; Dermatologic Agents; Furunculosis; Humans; Magnesium Sulfate; Male; Medication Errors; Potassium Permanganate; Treatment Outcome

Topics: Ascorbic Acid; Burns, Chemical; Emergency Treatment; Eye Burns; Humans; Male; Middle Aged; Potassium Permanganate; Therapeutic Irrigation

The treatment of double strictures in the airway and the oesophagus has always been time-consuming and causes additional suffering. A new technique using an open approach with the placement of two Montgomery silicone T-tubes to support and dilate the two strictures was successfully performed on a patient after caustic substance ingestion. Scar tissue was incised before two T-tubes were positioned into the larynx and oesophagus through a laryngo-fissure approach. The tubes remained in position for one year and no complications occurred. No foreign body sensation or prosthesis migration was observed and the patient had nearly normal peroral alimentation. After removal of the tubes, follow-up for an additional two years revealed no recurrence of the stenoses and normal alimentation without stridor. This technique permits simultaneous stenting of strictures of the larynx and oesophagus by using a connecting suture between the superior parts of two stents.

Topics: Adolescent; Burns, Chemical; Dilatation; Esophageal Stenosis; Female; Humans; Laryngostenosis; Potassium Permanganate; Stents

The author has analyzed 482 sick children younger than 2 years of age. The burn degree was established with the help of narcotized esophagoscopy and by parameters of homeostasis. The washing out of the chemical substance was performed by oral introduction of 6-9 liters of water and the following probe-elimination from the stomach within the first 12-24 hours. Correction of disturbed homeostasis was fulfilled if necessary. The independent nutrition was started on the 2nd-3rd day. The method allowed treatment of the burned esophagus without bougieurage provided the patient was admitted to the hospital during the 1st day. Nineteen patients died (3.9%). Long-term results were favorable.

Topics: Accidents, Home; Acetates; Acetic Acid; Burns, Chemical; Child, Preschool; Critical Care; Emergencies; Esophagus; Humans; Infant; Mouth; Potassium Permanganate

We report a case of corrosive burns to the mouth, oesophagus and trachea in a three-year-old boy who ingested potassium permanganate crystals. The pathophysiology and treatment options are discussed. The prevention of accidental ingestion could be improved with careful packaging of the solid tablet or crystalline forms.

Topics: Acute Disease; Burns, Chemical; Child, Preschool; Combined Modality Therapy; Crystallization; Esophagus; Humans; Male; Mouth; Potassium Permanganate; Trachea

A case of oesophageal stenosis following ingestion of potassium permanganate as an abortifacient is described.. A case is reported of a 20-year-old married female who developed esophageal stricture following consumption of potassium permanganate as an abortifacient. The woman was admitted in May 1985 with progressive dysphagia of 4 weeks duration. A week before the onset of symptoms, she was given, by a "village quack", a powder to be taken with sugar for inducing abortion in the 1st trimester of pregnancy. Immediately after consuming about 25 g of this powder, the patient experienced intense pain in the retrosternal area. She vomited repeatedly the whole day and aborted 12 hours later. Soon thereafter, she began to have difficulty in swallowing, which increased progressively over the next month before she came to the hospital for advice. Examination revealed mild dehydration. The oral cavity did not show any ulceration. A barium swallow showed a long, narrow stricture of the esophagus. Endoscopy revealed a mild esophagitis from 20-24 cm, beyond which a long, narrow stricture could be seen. A feeding tube was put in, and 2 weeks later endoscopic dilatation with Eder-Puestow dilators was begun. She underwent 6 sittings of dilatation which led to complete recovery of her symptoms. A followup barium study was not done since the patient had conceived again. A sample of the "powder" which she had consumed was chemically analyzed and found to be potassium permanganate. This case illustrates that potassium permanganate (KMn04) can cause severe chemical burns to the esophagus, which on healing may reult in fibrosis leading to stricture formation.

Topics: Abortifacient Agents; Adult; Burns, Chemical; Esophageal Stenosis; Female; Humans; Potassium Permanganate

Topics: Ascorbic Acid; Burns, Chemical; Chemical Phenomena; Chemistry; Conjunctiva; Corneal Injuries; Eye Burns; Female; Humans; Infant, Newborn; Potassium Permanganate

Topics: Adult; Burns, Chemical; Critical Care; Emergencies; Humans; Male; Potassium Permanganate; Resuscitation; Time Factors

Topics: Accidents, Home; Burns, Chemical; Child, Preschool; Eye Burns; Humans; Male; Potassium Permanganate

Topics: Ascorbic Acid; Burns, Chemical; Eye Injuries; Female; Humans; Potassium Permanganate

Potassium permanganate tablets are caustic and it has been suggested that they should be removed straightaway by gastrostomy, immediately after swallowing. Some operators have been impressed by the macroscopic appearance of the stomach and have carried out gastrectomy. However, the lesions were only fairly superficial on pathological examination. In the light of a new case and 21 similar cases, treated at the Fernand Widal hospital, the authors discuss other cases in the literature. They conclude: the extreme rareness of digestive perforation; the absence of toxicity of breakdown products of potassium permanganate. They propose treatment of neutralisation of the permanganate with sodium hyposulphite, gastric lavage and supervision on a surgical unit. In case of perforation, they believe that the operation should be conservative.

Topics: Adult; Aluminum Hydroxide; Animals; Burns, Chemical; Female; Gastric Lavage; Gastric Mucosa; Gastrostomy; Humans; Milk; Necrosis; Potassium Permanganate; Stomach; Stomach Diseases; Stomach Rupture; Suicide, Attempted; Thiosulfates

Topics: Burns, Chemical; Catheterization; Gastric Mucosa; Humans; Laryngoscopy; Poisoning; Potassium Permanganate; Radiography; Stomach; Tablets; Thiosulfates

Topics: Burns, Chemical; Cantharidin; Caustics; Chromates; Corrosion; Cresols; Environmental Exposure; Humans; Hydrochloric Acid; Mustard Compounds; Nitrates; Oxidation-Reduction; Phenols; Potassium Permanganate; Sodium Hypochlorite; Sulfuric Acids

Topics: Adult; Burns, Chemical; Eye Burns; Humans; Male; Potassium Permanganate

Potassium permanganate in tablets is still used in Mexico under the wrong belief that it will induce abortion. What it does, instead, is to provoke deep burns and ulcers in the vaginal walls, and to cause serious hemorrhage. This study investigates 200 women who used potassium permanganate as an abortifacient agent, and who needed hospitalization. Average age was 28; 58.5% had 4 or more children; 88.5% were married, and 11.5% were not; all patients belonged to the lowest socioeconomic class. Many had antecedents of induced abortion, and most had been amenorrheic for only 4-5 weeks. 23.5% of patients was not pregnant. Acute anemia was the most common complication, followed by hypovolemic shock. In this series there was 21.5% of diagnostic error, which shows the importance of suspecting this pathologic entity in women bleeding profusely and for whom induced abortion is suspected.

Topics: Abortion, Criminal; Adult; Burns, Chemical; Female; Humans; Potassium Permanganate; Pregnancy; Vagina; Vaginal Diseases

Topics: Abortion, Criminal; Adolescent; Adult; Burns, Chemical; Caustics; Female; Humans; Potassium Permanganate; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Vaginal Diseases

Potassium permanganate, a drug formerly used for urological and dermatological conditions and with clear veterinary indications, is an oxidizing agent which is reduced to potassium hydroxide and manganese dioxide with the liberation of nascent oxygen, when it is brought into contact with tissue, water, or moisture. Since the second World War, reports of the drug's use as an abortifacient by nonmedical persons have increased. Because of the agent's veterinary indications, it was available over-the-counter, and apparently American soldiers are blamed for introducing British women to its abortifacient effects. This short article reviews published cases of attempted abortion by injection of the drug into the vagina. In addition, this paper describes 23 cases of intravaginal potassium permanganate burns seen over a 25-month period (1962-1964) to draw attention to the fad use of this agent for aborting. Speculum views of vaginal damage caused by the agent are depicted. The use of direct speculum examination for diagnosis is emphasized. Though all cases experienced fairly immediate per vagina bleeding post self-induced treatment, none terminated her pregnancy; instead, the caustic agents burned the vaginal fornix severely; in fact, the vast majority of cases delivered liveborn, normal fetuses after attempted abortion. Management is simple: arrest the hemorrhage, resuscitate the patient, and replace blood loss.

Topics: Abortion, Criminal; Adult; Burns, Chemical; Female; Humans; Middle Aged; Potassium Permanganate; Pregnancy

Topics: Accidents; Adult; Ammonia; Burns, Chemical; Caustics; Female; Formaldehyde; Gastritis; Humans; Hydrochloric Acid; Male; Mental Disorders; Mercury Poisoning; Middle Aged; Potassium Permanganate; Suicide

Topics: Abortion, Criminal; Burns, Chemical; Diagnosis, Differential; Female; Humans; Potassium Permanganate; Pregnancy; Ulcer

Topics: Burns, Chemical; Eye Burns; Humans; Potassium Permanganate

Topics: Abortion, Criminal; Adult; Burns, Chemical; Female; Genital Diseases, Female; Humans; Middle Aged; Potassium Permanganate; Pregnancy

Topics: Abortion, Criminal; Abortion, Induced; Abortion, Spontaneous; Black People; Burns, Chemical; Criminals; Diagnosis, Differential; Female; Humans; Potassium Permanganate; Pregnancy; Pregnancy, Ectopic; Vagina

Topics: Abortion, Criminal; Abortion, Induced; Anti-Infective Agents, Local; Burns; Burns, Chemical; Criminals; Female; Genitalia, Female; Humans; Potassium Permanganate; Pregnancy