potassium iodide and Injuries, Radiation studies

Potassium Iodide: An inorganic compound that is used as a source of iodine in thyrotoxic crisis and in the preparation of thyrotoxic patients for thyroidectomy. (From Dorland, 27th ed)
potassium iodide : A metal iodide salt with a K(+) counterion. It is a scavenger of hydroxyl radicals.

Research Excerpts

Excerpt	Relevance	Reference
" The present study demonstrates that a single oral administration of 38 mg of iodide produces a thyroid-blocking effect equivalent to that of 76 mg of iodide, suggesting that a reevaluation of the stable iodine dosage during radiation emergencies in iodine-rich areas such as Japan is warranted."	2.71	Thyroid blockade during a radiation emergency in iodine-rich areas: effect of a stable-iodine dosage. ( Aoyagi, K; Ishigaki, J; Ishigaki, K; Mine, M; Nakamura, Y; Takamura, N; Yamashita, S, 2004)
" Rats were administered (131)I- and 3 hours later dosed with either saline, 30 mg/kg of NH(4)ClO(4) or 30 mg/kg of KI."	1.38	Radioactive iodide (131 I-) excretion profiles in response to potassium iodide (KI) and ammonium perchlorate (NH4ClO4) prophylaxis. ( Blount, B; Dallas, C; Fisher, J; Harris, C; Rollor, E; Valentin-Blasini, L; White, C, 2012)
"Ammonium perchlorate was more effective than stable iodide for whole-body radioprotectant effectiveness."	1.35	Evaluation of potassium iodide (KI) and ammonium perchlorate (NH4ClO4) to ameliorate 131I- exposure in the rat. ( Blount, BC; Dallas, CE; Ferguson, DC; Fisher, JW; Harris, CA; Rollor, EA; Taylor, MA; Valentin-Blasini, L, 2009)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (34.69)	18.7374
1990's	4 (8.16)	18.2507
2000's	17 (34.69)	29.6817
2010's	11 (22.45)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Benderitter, M	2
Pourcher, T	1
Martin, JC	1
Darcourt, J	1
Guigon, P	1
Caire-Maurisier, F	1
Pech, A	1
Lebsir, D	2
Rosique, C	1
Guglielmi, J	1
Rebière, F	1
Tack, K	1
Phan, G	1
Lestaevel, P	1
Souidi, M	2
Jourdain, JR	2
Cohen, DPA	1
Braverman, ER	1
Blum, K	1
Loeffke, B	1
Baker, R	1
Kreuk, F	1
Yang, SP	1
Hurley, JR	1
Dreger, S	2
Pfinder, M	2
Christianson, L	2
Lhachimi, SK	2
Zeeb, H	3
Turai, I	1
Reiners, C	1
Schneider, R	1
Akashi, M	1
Akl, EA	1
Li, C	1
Murith, C	1
Van Bladel, L	1
Yamashita, S	3
Vitti, P	1
Carr, Z	1
Jang, M	2
Kim, HK	2
Choi, CW	2
Kang, CS	2
Harris, CA	1
Fisher, JW	1
Rollor, EA	1
Ferguson, DC	1
Blount, BC	1
Valentin-Blasini, L	2
Taylor, MA	1
Dallas, CE	1
Adalja, AA	2
Fitzgerald, J	1
Wollner, SB	1
Morhard, R	1
Cicero, A	1
Inglesby, TV	1
Harris, C	1
Dallas, C	1
Rollor, E	1
White, C	1
Blount, B	1
Fisher, J	1
Zwolinski, LR	1
Stanbury, M	1
Manente, S	1
van Bekkum, DW	1
Noteboom, JL	1
Bacher, K	1
Brans, B	1
Monsieurs, M	1
De Winter, F	1
Dierckx, RA	1
Thierens, H	1
Harrison, TW	1
Gustafson, EM	1
Dixon, JK	1
Johnson, JR	1
Redlener, I	1
Markenson, D	1
Takamura, N	2
Nakamura, Y	1
Ishigaki, K	1
Ishigaki, J	1
Mine, M	1
Aoyagi, K	2
Iwauchi, T	1
Lawrence, DT	1
Kirk, MA	1
Crocker, DG	1
Broga, DW	1
Gilbert, MA	1
Murphy, D	1
Kallee, E	1
Nauman, J	2
Wolff, J	1
Franić, Z	1
Zanzonico, PB	1
Becker, DV	1
Delange, F	1
Kluger, J	1
van Santen, HM	1
de Kraker, J	1
van Eck, BL	1
de Vijlder, JJ	1
Vulsma, T	1
Miller, K	1
Small, WE	1
Kelly, JU	1
Young, RW	1
Linnemann, RE	1
Schlumberger, M	1
Parmentier, N	1
Chavaudra, J	1
Parmentier, C	1
Tubiana, M	1
Abdel-Nabi, H	1
Waldman, WJ	1
Hinkle, GH	1
Miller, EA	1
Trembath, L	1
Olsen, JO	1
Martin, EW	1
Mackowiak, ED	1
Hagen, GA	1
Ouellette, RP	1
Chapman, EM	1
Bordell, FL	1
Sayeg, JA	1
Wald, N	1
Wechsler, RL	1
Hör, G	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter[NCT04856488]			Phase 3	182 participants (Anticipated)	Interventional	2021-11-18	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Managing terrorism or accidental nuclear errors, preparing for iodine-131 emergencies: a comprehensive review. International journal of environmental research and public health, 2014, Apr-15, Volume: 11, Issue:4 Topics: Humans; Iodine Radioisotopes; Potassium Iodide; Radiation Injuries; Radioactive Hazard Release; Terr	2014
The effects of iodine blocking following nuclear accidents on thyroid cancer, hypothyroidism, and benign thyroid nodules: design of a systematic review. Systematic reviews, 2015, Sep-24, Volume: 4 Topics: Evidence-Based Medicine; Humans; Iodine Radioisotopes; Potassium Iodide; Practice Guidelines as Topi	2015
The effects of iodine blocking on thyroid cancer, hypothyroidism and benign thyroid nodules following nuclear accidents: a systematic review. Journal of radiological protection : official journal of the Society for Radiological Protection, 2016, Volume: 36, Issue:4 Topics: Humans; Hypothyroidism; Iodine Radioisotopes; Potassium Iodide; Practice Guidelines as Topic; Radiat	2016
Radiologic emergency: protecting schoolchildren and the public. The American journal of nursing, 2003, Volume: 103, Issue:5 Topics: Child; Disaster Planning; Emergencies; Humans; Potassium Iodide; Radiation Injuries; Radioactive Haz	2003
Chemical terrorism attacks: update on antidotes. Emergency medicine clinics of North America, 2007, Volume: 25, Issue:2 Topics: Antidotes; Atropine; Botulinum Toxins; Chemical Terrorism; Humans; Muscarinic Antagonists; Potassium	2007
Nuclear reactor accidents--the use of KI as a blocking agent against radioiodine uptake in the thyroid--a review. Health physics, 1984, Volume: 46, Issue:6 Topics: Accidents; Adolescent; Adult; Aerosols; Aged; Air Pollution, Radioactive; Child; Half-Life; Humans;	1984

Article	Year
Thyroid uptake and radiation dose after (131)I-lipiodol treatment: is thyroid blocking by potassium iodide necessary? European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:10 Topics: Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Dose-Response Relationship, Radiation; Drug Admin	2002
Thyroid blockade during a radiation emergency in iodine-rich areas: effect of a stable-iodine dosage. Journal of radiation research, 2004, Volume: 45, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Female; Humans; Hyperthyr	2004
Comparison of high and low dosage levels of 131-I in the treatment of thyrotoxicosis. The New England journal of medicine, 1967, Sep-14, Volume: 277, Issue:11 Topics: Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Potassium Iodide; Radiation Injuri	1967

potassium iodide and Injuries, Radiation

Research Excerpts

Research

Studies (49)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
DO MULTIPLE ADMINISTRATIONS OF STABLE IODINE PROTECT POPULATION CHRONICALLY EXPOSED TO RADIOACTIVE IODINE: WHAT IS PRIODAC RESEARCH PROGRAM (2014-22) TEACHING US? Radiation protection dosimetry, 2018, Dec-01, Volume: 182, Issue:1 Topics: Dose-Response Relationship, Radiation; Humans; Iodine Radioisotopes; Neoplasms, Radiation-Induced; P	2018
A systems biology approach to propose a new mechanism of regulation of repetitive prophylaxis of stable iodide on sodium/iodide symporter (NIS). Biochimie, 2019, Volume: 162 Topics: Animals; Biological Transport; Potassium Iodide; Radiation Injuries; Rats; Symporters; Systems Biolo	2019
Thyroid Blocking Policy in Hungary and Clarification of Terminology in the Light of Recommendations by International Organisations. Radiation protection dosimetry, 2016, Volume: 171, Issue:1 Topics: Disaster Planning; Europe; European Union; Guidelines as Topic; Health Promotion; Humans; Hungary; I	2016
The First Meeting of the WHO Guideline Development Group for the Revision of the WHO 1999 Guidelines for Iodine Thyroid Blocking. Radiation protection dosimetry, 2016, Volume: 171, Issue:1 Topics: Adolescent; Adult; Child; Child, Preschool; European Union; Evidence-Based Medicine; Female; Fukushi	2016
Thyroid dose estimation with potassium iodide (KI) administration in a nuclear emergency. Radiation protection dosimetry, 2008, Volume: 132, Issue:3 Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Infant; Iodine Radioisotopes; Potassium Iodide;	2008
Evaluation of potassium iodide (KI) and ammonium perchlorate (NH4ClO4) to ameliorate 131I- exposure in the rat. Journal of toxicology and environmental health. Part A, 2009, Volume: 72, Issue:14 Topics: Animals; Iodine; Iodine Radioisotopes; Male; Perchlorates; Potassium Iodide; Quaternary Ammonium Com	2009
Use of potassium iodide (KI) in a nuclear emergency. Biosecurity and bioterrorism : biodefense strategy, practice, and science, 2011, Volume: 9, Issue:4 Topics: Disaster Planning; Drug Storage; Health Policy; Humans; Potassium Iodide; Radiation Injuries; Radiat	2011
After Fukushima: managing the consequences of a radiological release. Biosecurity and bioterrorism : biodefense strategy, practice, and science, 2012, Volume: 10, Issue:2 Topics: Disaster Planning; Disasters; Emergency Responders; Environmental Restoration and Remediation; Feder	2012
Radioactive iodide (131 I-) excretion profiles in response to potassium iodide (KI) and ammonium perchlorate (NH4ClO4) prophylaxis. International journal of environmental research and public health, 2012, Volume: 9, Issue:8 Topics: Animals; Iodine; Iodine Radioisotopes; Male; Perchlorates; Potassium Iodide; Quaternary Ammonium Com	2012
Nuclear power plant emergency preparedness: results from an evaluation of Michigan's potassium iodide distribution program. Disaster medicine and public health preparedness, 2012, Volume: 6, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Disaster Planning; Disasters; Female; Financing, Government; Humans;	2012
Major radiation exposure. The New England journal of medicine, 2002, Sep-19, Volume: 347, Issue:12 Topics: Adult; Breast Feeding; Child; Female; Humans; Potassium Iodide; Pregnancy; Pregnancy Complications;	2002
Radiation disasters and children. Pediatrics, 2003, Volume: 111, Issue:6 Pt 1 Topics: Child; Disaster Planning; Humans; Neoplasms, Radiation-Induced; Potassium Iodide; Practice Guideline	2003
On the distribution of potassium iodide to members of the public in anticipation of an accidental release of radioiodine. Radiation protection dosimetry, 2003, Volume: 104, Issue:3 Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Decontamination; Delivery of Health Care; Disaster	2003
Disaster and terrorism preparedness: what pediatricians need to know. Disease-a-month : DM, 2004, Volume: 50, Issue:1 Topics: Adolescent; Adult; Bioterrorism; Chemical Warfare Agents; Child; Child, Preschool; Disaster Planning	2004
Steam leak accident at nuclear power plant in Japan. Endocrine journal, 2004, Volume: 51, Issue:6 Topics: Child, Preschool; Humans; Infant; Japan; Potassium Iodide; Power Plants; Radiation Injuries; Radioac	2004
Age-dependent potassium iodide effect on the thyroid irradiation by 131I and 133I in the nuclear emergency. Radiation protection dosimetry, 2008, Volume: 130, Issue:4 Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Humans; Infant; Iodides; Iodine Radioisotop	2008
A review of three incidents involving the release of 125I from seeds interstitially implanted within the prostate gland. Health physics, 1983, Volume: 45, Issue:3 Topics: Accidents; Brachytherapy; Humans; Iodine Radioisotopes; Male; Potassium Iodide; Prostatic Neoplasms;	1983
Iodide-an Rx for radiation accident. The American journal of nursing, 1982, Volume: 82, Issue:1 Topics: Half-Life; Humans; Iodine Radioisotopes; Potassium Iodide; Radiation Injuries; Thyroid Gland	1982
Resolution concerning the stockpiling of potassium iodide in New York City in the event of a nuclear accident. The Committee on Public Health, The New York Academy of Medicine. Bulletin of the New York Academy of Medicine, 1981, Volume: 57, Issue:5 Topics: Adult; Child; Disaster Planning; Humans; Infant; Neoplasms, Radiation-Induced; New York City; Nuclea	1981
[Uses and risk of iodine prophylaxis in nuclear reactor accidents]. Der Internist, 1981, Volume: 22, Issue:5 Topics: Accidents; Animals; Humans; Iodine; Nuclear Reactors; Potassium Iodide; Radiation Injuries; Rats; So	1981
Final recommendations issued on potassium iodide. FDA drug bulletin, 1982, Volume: 12, Issue:3 Topics: Adult; Child; Child, Preschool; Emergencies; Humans; Infant; Potassium Iodide; Radiation Injuries; T	1982
Iodide prophylaxis in Poland after the Chernobyl reactor accident: benefits and risks. The American journal of medicine, 1993, Volume: 94, Issue:5 Topics: Accidents; Adolescent; Adult; Child; Child, Preschool; Female; Food Contamination, Radioactive; Huma	1993
Stockpiling safety? Environmental health perspectives, 1998, Volume: 106, Issue:3 Topics: Humans; Potassium Iodide; Radiation Injuries; Radioactive Hazard Release	1998
Iodine prophylaxis and nuclear accidents. Arhiv za higijenu rada i toksikologiju, 1999, Volume: 50, Issue:2 Topics: Humans; Iodine Radioisotopes; Potassium Iodide; Power Plants; Radiation Injuries; Radioactive Fallou	1999
Effects of time of administration and dietary iodine levels on potassium iodide (KI) blockade of thyroid irradiation by 131I from radioactive fallout. Health physics, 2000, Volume: 78, Issue:6 Topics: Administration, Oral; Adult; Diet; Humans; Iodine; Iodine Radioisotopes; Potassium Iodide; Radiation	2000
Iodine prophylaxis following nuclear accidents. Concern for the neonate? Cellular and molecular biology (Noisy-le-Grand, France), 2001, Volume: 47, Issue:3 Topics: Animals; Humans; Infant, Newborn; Iodine; Poland; Potassium Iodide; Radiation Injuries; Radioactive	2001
Is this the next Cipro? Not quite. Time, 2001, Dec-17, Volume: 158, Issue:26 Topics: Androstenediol; Disaster Planning; Government Agencies; Humans; Potassium Iodide; Radiation Injuries	2001
High incidence of thyroid dysfunction despite prophylaxis with potassium iodide during (131)I-meta-iodobenzylguanidine treatment in children with neuroblastoma. Cancer, 2002, Apr-01, Volume: 94, Issue:7 Topics: 3-Iodobenzylguanidine; Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Follow-Up Studi	2002
Our way of life has changed forever. Health physics, 2002, Volume: 82, Issue:5 Suppl Topics: Disaster Planning; Humans; Potassium Iodide; Radiation Injuries; Terrorism; United States	2002
Fast action. American family physician, 1979, Volume: 20, Issue:1 Topics: Disasters; Drug Industry; Government; Humans; Pennsylvania; Potassium Iodide; Radiation Injuries; Un	1979
Mobilizing for Three Mile Island--the disaster that wasn't. American pharmacy, 1979, Volume: 19, Issue:6 Topics: Disasters; Humans; Industry; Nuclear Reactors; Pennsylvania; Potassium Iodide; Radiation Injuries; U	1979
[Study of the effects of some prophylactic measures and radiological contamination in Poland after the Czernobyl accident; Introduction to the research program MZ-XVII]. Endokrynologia Polska, 1991, Volume: 42, Issue:2 Topics: Adolescent; Adult; Air Pollutants, Radioactive; Child; Child, Preschool; Female; Fetus; Humans; Infa	1991
The use of an investigational radiopharmaceutical in neuroblastoma: a nursing perspective. Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses, 1989, Volume: 6, Issue:4 Topics: 3-Iodobenzylguanidine; Adult; Child; Clinical Protocols; Humans; Iodine Radioisotopes; Iodobenzenes;	1989
Chernobyl in retrospect. Pharmacology & therapeutics, 1988, Volume: 39, Issue:1-3 Topics: Accidents; Blood Transfusion; Bone Marrow Transplantation; Dose-Response Relationship, Radiation; Fi	1988
Soviet medical response to the Chernobyl nuclear accident. JAMA, 1987, Aug-07, Volume: 258, Issue:5 Topics: Accidents; Bone Marrow Transplantation; Burns; Disaster Planning; Emergency Medical Services; Humans	1987
[Management in case of contamination by iodine radioisotopes]. La Revue du praticien, 1987, Oct-08, Volume: 37, Issue:40 Topics: Humans; Iodine Radioisotopes; Potassium Iodide; Radiation Injuries; Thyroid Diseases; Thyroid Gland	1987
Comparison of L-thyroxine and a saturated solution of potassium iodide in preventing damage to the thyroid following iodine-131-labeled antibody injection. NCI monographs : a publication of the National Cancer Institute, 1987, Issue:3 Topics: Animals; DNA Damage; Iodine Radioisotopes; Male; Potassium Iodide; Radiation Injuries; Rats; Rats, I	1987
Distribution of KI. Health physics, 1985, Volume: 48, Issue:3 Topics: Accidents; Humans; Nuclear Energy; Potassium Iodide; Radiation Injuries	1985
In vivo measured effective half-life of 125 I in human thyroids. Physics in medicine and biology, 1972, Volume: 17, Issue:3 Topics: Accidents, Occupational; Half-Life; Humans; Iodine; Iodine Isotopes; Maximum Allowable Concentration	1972
[Critical evaluation of renal nuclear diagnostic methods in pediatrics]. Archiv fur Kinderheilkunde, 1968, Volume: 176, Issue:3 Topics: Adolescent; Child, Preschool; Diuretics; Humans; Infant; Kidney; Kidney Diseases; Male; Methods; Pot	1968