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potassium chloride and Nerve Degeneration

potassium chloride has been researched along with Nerve Degeneration in 16 studies

Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
" The toxic effect of gamma-vinyl-GABA was mimicked by a 24-h treatment with GABA (100 microM) and the GABA(A) receptor agonist, muscimol (10 microM), but not the GABA(B) receptor agonist, baclofen (10 microM)."1.31GABA(A)-mediated toxicity of hippocampal neurons in vitro. ( Lukasiuk, K; Pitkänen, A, 2000)
"Taurine release was characterized in rat striatum that was excitotoxically lesioned compared to normal conditions."1.30Potassium-stimulated taurine release and nitric oxide synthase activity during quinolinic acid lesion of the rat striatum. ( Böckelmann, R; Reiser, M; Wolf, G, 1998)
" In contrast, neither QA up to 5 mM nor trans-ACPD had a significant toxic effect in either KCl group."1.30NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. ( Chen, Q; Reiner, A; Surmeier, DJ, 1999)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's4 (25.00)18.2507
2000's8 (50.00)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woitecki, AM1
Müller, JA1
van Loo, KM1
Sowade, RF1
Becker, AJ1
Schoch, S1
Farrand, AQ1
Gregory, RA1
Bäckman, CM1
Helke, KL1
Boger, HA1
Saliba, SW1
Vieira, EL1
Santos, RP1
Candelario-Jalil, E1
Fiebich, BL1
Vieira, LB1
Teixeira, AL1
de Oliveira, AC1
Shahar, T1
House, SB1
Gainer, H1
Shirasaki, Y1
Kanazawa, Y1
Morishima, Y1
Makino, M1
Dairam, A1
Chetty, P1
Daya, S1
Han, F1
Shioda, N1
Moriguchi, S1
Qin, ZH1
Fukunaga, K1
Singh, KK1
Park, KJ1
Hong, EJ1
Kramer, BM1
Greenberg, ME1
Kaplan, DR1
Miller, FD1
Gualandris, A1
Jones, TE1
Strickland, S1
Tsirka, SE1
Böckelmann, R1
Reiser, M1
Wolf, G1
Allan, SM1
Lawrence, CB1
Rothwell, NJ1
Chen, Q1
Surmeier, DJ1
Reiner, A1
Isaev, NK1
Stelmashook, EV1
Halle, A1
Harms, C1
Lautenschlager, M1
Weih, M1
Dirnagl, U1
Victorov, IV1
Zorov, DB1
Lukasiuk, K1
Pitkänen, A1
Holmin, S1
von Gertten, C1
Sandberg-Nordqvist, AC1
Lendahl, U1
Mathiesen, T1
Strich, SJ1

Other Studies

16 other studies available for potassium chloride and Nerve Degeneration

ArticleYear
Identification of Synaptotagmin 10 as Effector of NPAS4-Mediated Protection from Excitotoxic Neurodegeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-02, Volume: 36, Issue:9

    Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Cell Survival; Cells, Cultured; Fe

2016
Altered glutamate release in the dorsal striatum of the MitoPark mouse model of Parkinson's disease.
    Brain research, 2016, 11-15, Volume: 1651

    Topics: Animals; Corpus Striatum; Dopamine; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Pro

2016
Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid.
    Journal of neuroinflammation, 2017, 01-31, Volume: 14, Issue:1

    Topics: Animals; Body Weight; Corpus Striatum; Cytokines; Disease Models, Animal; Dose-Response Relationship

2017
Neural activity protects hypothalamic magnocellular neurons against axotomy-induced programmed cell death.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jul-21, Volume: 24, Issue:29

    Topics: Animals; Apoptosis; Axotomy; Cell Survival; Male; Median Eminence; Nerve Degeneration; Neurites; Neu

2004
Involvement of calmodulin in neuronal cell death.
    Brain research, 2006, Apr-14, Volume: 1083, Issue:1

    Topics: Animals; Binding Sites; Brain; Brain Ischemia; Calcium; Calcium Signaling; Calmodulin; Cell Death; C

2006
Non-steroidal anti-inflammatory agents, tolmetin and sulindac, attenuate oxidative stress in rat brain homogenate and reduce quinolinic acid-induced neurodegeneration in rat hippocampal neurons.
    Metabolic brain disease, 2006, Volume: 21, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Dizocilpine Maleate; Excitatory A

2006
Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Down-Regulation; Excitator

2008
Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration.
    Nature neuroscience, 2008, Volume: 11, Issue:6

    Topics: Animals; Animals, Newborn; Axons; Axotomy; Brain-Derived Neurotrophic Factor; Cells, Cultured; Chole

2008
Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Apr-01, Volume: 16, Issue:7

    Topics: Animals; Blotting, Northern; Calcium; Calcium Channel Blockers; Cricetinae; Gene Expression; Membran

1996
Potassium-stimulated taurine release and nitric oxide synthase activity during quinolinic acid lesion of the rat striatum.
    Neurochemical research, 1998, Volume: 23, Issue:4

    Topics: Animals; Corpus Striatum; Cyclic GMP; Male; Microdialysis; Nerve Degeneration; Neurotoxins; NG-Nitro

1998
Interleukin-1 beta and interleukin-1 receptor antagonist do not affect glutamate release or calcium entry in rat striatal synaptosomes.
    Molecular psychiatry, 1998, Volume: 3, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cerebral Cortex; Chelati

1998
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
    Experimental neurology, 1999, Volume: 159, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi

1999
Inhibition of Na(+),K(+)-ATPase activity in cultured rat cerebellar granule cells prevents the onset of apoptosis induced by low potassium.
    Neuroscience letters, 2000, Mar-31, Volume: 283, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cerebellar Cortex;

2000
GABA(A)-mediated toxicity of hippocampal neurons in vitro.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Animals; Anticonvulsants; Bicuculline; Cell Survival; Cells, Cultured; Epilepsy; Female; Fetus; GABA

2000
Induction of astrocytic nestin expression by depolarization in rats.
    Neuroscience letters, 2001, Nov-16, Volume: 314, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Brain Injuries; Brain Ischemia; Cell Differentiation; Cerebral Corte

2001
Notes on the Marchi method for staining degenerating myelin in the peripheral and central nervous system.
    Journal of neurology, neurosurgery, and psychiatry, 1968, Volume: 31, Issue:2

    Topics: Acetates; Animals; Central Nervous System; Formaldehyde; Haplorhini; Humans; Methods; Nerve Degenera

1968