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potassium chloride and Migraine Disorders

potassium chloride has been researched along with Migraine Disorders in 19 studies

Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Oxcarbazepine did not suppress spreading depression either after a single dose or after daily treatment for 5 weeks."1.37Oxcarbazepine does not suppress cortical spreading depression. ( Ayata, C; Dileköz, E; Hoffmann, U; Kudo, C, 2011)
"The S218L mutants also develop coma and seizures and sometimes die."1.37Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. ( Ayata, C; Baek, K; Dilekoz, E; Eikermann-Haerter, K; Ferrari, MD; Hoffmann, U; Kim, YR; Moskowitz, MA; Qin, T; van den Maagdenberg, AM; Waeber, C; Wang, Y; Yuzawa, I, 2011)
"Migraine is one of the risk factor for ischemic stroke."1.37Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity. ( Iizuka, R; Ishii, M; Kiuchi, Y; Mori, Y; Shimizu, S, 2011)
"The prevalence of migraine is higher in women than in men, and changes in 17beta-estradiol levels seem to affect the frequency of attacks in female migraineurs."1.34Rat carotid artery responses to alpha-adrenergic receptor agonists and 5-HT after ovariectomy and hormone replacement. ( Boomsma, F; Gupta, S; MaassenVanDenbrink, A; Mehrotra, S; Saxena, PR; Villalón, CM, 2007)
"The prevalence of migraine is much greater in female than male individuals."1.34Reduced threshold for cortical spreading depression in female mice. ( Arnold, AP; Brennan, KC; Charles, AC; López Valdés, HE; Romero Reyes, M, 2007)
"Migraine headache is proposed to be mediated by nitric oxide (NO)."1.31Cortical spreading depression produces increased cGMP levels in cortex and brain stem that is inhibited by tonabersat (SB-220453) but not sumatriptan. ( Hirst, WD; Parsons, AA; Read, SJ; Upton, N, 2001)
"Although the recurrent headache of migraine is of unknown origin and is not accompanied by an identifiable pathology, it shares with intracranial headaches features that suggest an exaggerated intracranial mechanosensitivity (worsening of the pain by coughing, breath-holding or sudden head movement)."1.29Sensitization of meningeal sensory neurons and the origin of headaches. ( Burstein, R; Raymond, SA; Strassman, AM, 1996)
"The pathophysiology of migraine is still poorly understood but it is widely accepted that various 'triggers', including fluctuations in the concentrations of circulating ovarian steroid levels, may initiate alterations in the activity of the intracranial vasculature and its efferent and afferent innervation."1.28New possibilities for anti-migraine drugs: prostanoid antagonists and progesterone-mimicking stabilizers of excitable cells. ( Leathard, HL, 1989)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's10 (52.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurauchi, Y1
Haruta, M1
Tanaka, R1
Sasagawa, K1
Ohta, J1
Hisatsune, A1
Seki, T1
Katsuki, H1
Saengjaroentham, C1
Supornsilpchai, W1
Ji-Au, W1
Srikiatkhachorn, A1
Maneesri-le Grand, S1
Hoffmann, J1
Supronsinchai, W1
Akerman, S1
Andreou, AP1
Winrow, CJ1
Renger, J1
Hargreaves, R1
Goadsby, PJ1
Alabwah, Y1
Ji, Y1
Seminowicz, DA1
Quiton, RL1
Masri, R1
Bogdanov, VB2
Middleton, NA1
Theriot, JJ1
Parker, PD1
Abdullah, OM1
Ju, YS1
Hartings, JA1
Brennan, KC3
Noseda, R1
Constandil, L1
Bourgeais, L1
Chalus, M1
Villanueva, L1
Hoffmann, U2
Dileköz, E2
Kudo, C1
Ayata, C2
Eikermann-Haerter, K1
Yuzawa, I1
Qin, T1
Wang, Y1
Baek, K1
Kim, YR1
Waeber, C1
Ferrari, MD1
van den Maagdenberg, AM1
Moskowitz, MA1
Ishii, M1
Iizuka, R1
Kiuchi, Y1
Mori, Y1
Shimizu, S1
Bogdanova, OV1
Koulchitsky, SV1
Chauvel, V1
Multon, S1
Makarchuk, MY1
Renshaw, PF1
Schoenen, J1
Gorji, A1
Zahn, PK1
Pogatzki, EM1
Speckmann, EJ1
Mehrotra, S1
Gupta, S1
Villalón, CM1
Boomsma, F1
Saxena, PR1
MaassenVanDenbrink, A1
Romero Reyes, M1
López Valdés, HE1
Arnold, AP1
Charles, AC1
Peroutka, SJ1
Allen, GS1
Richter, F1
Lehmenkühler, A1
Strassman, AM1
Raymond, SA1
Burstein, R1
Smith, MI1
Read, SJ2
Chan, WN1
Thompson, M1
Hunter, AJ1
Upton, N2
Parsons, AA2
Hirst, WD1
Leathard, HL1

Other Studies

19 other studies available for potassium chloride and Migraine Disorders

ArticleYear
Propranolol prevents cerebral blood flow changes and pain-related behaviors in migraine model mice.
    Biochemical and biophysical research communications, 2019, 01-08, Volume: 508, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Di

2019
Serotonin depletion can enhance the cerebrovascular responses induced by cortical spreading depression via the nitric oxide pathway.
    The International journal of neuroscience, 2015, Volume: 125, Issue:2

    Topics: Analysis of Variance; Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Disease M

2015
Evidence for orexinergic mechanisms in migraine.
    Neurobiology of disease, 2015, Volume: 74

    Topics: Animals; Azepines; Benzimidazoles; Central Nervous System Agents; Cortical Spreading Depression; Dis

2015
Alcohol-triggered signs of migraine: An animal model.
    Somatosensory & motor research, 2016, Volume: 33, Issue:1

    Topics: Alcohols; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Psychological; Disease Mo

2016
Susceptibility of Primary Sensory Cortex to Spreading Depolarizations.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 04-27, Volume: 36, Issue:17

    Topics: Animals; Brain Injuries; Cortical Spreading Depression; Humans; Ketamine; Male; Mice; Mice, Inbred C

2016
Changes of meningeal excitability mediated by corticotrigeminal networks: a link for the endogenous modulation of migraine pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Oct-27, Volume: 30, Issue:43

    Topics: Animals; Biotin; Cerebral Cortex; Cortical Spreading Depression; Electric Stimulation; Immunohistoch

2010
Oxcarbazepine does not suppress cortical spreading depression.
    Cephalalgia : an international journal of headache, 2011, Volume: 31, Issue:5

    Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Cortical Spreading Depression; Electric Stimulation;

2011
Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Apr-13, Volume: 31, Issue:15

    Topics: Animals; Animals, Genetically Modified; Cardiovascular Physiological Phenomena; Cerebellar Ataxia; C

2011
Neuroprotection by lomerizine, a prophylactic drug for migraine, against hydrogen peroxide-induced hippocampal neurotoxicity.
    Molecular and cellular biochemistry, 2011, Volume: 358, Issue:1-2

    Topics: Animals; Benzamides; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; HEK293 Cells; H

2011
Behavior in the open field predicts the number of KCl-induced cortical spreading depressions in rats.
    Behavioural brain research, 2013, Jan-01, Volume: 236, Issue:1

    Topics: Animals; Antimanic Agents; Anxiety; Behavior, Animal; Cortical Spreading Depression; Electrodes, Imp

2013
Spinal and cortical spreading depression enhance spinal cord activity.
    Neurobiology of disease, 2004, Volume: 15, Issue:1

    Topics: Action Potentials; Animals; Cortical Spreading Depression; In Vitro Techniques; Migraine Disorders;

2004
Rat carotid artery responses to alpha-adrenergic receptor agonists and 5-HT after ovariectomy and hormone replacement.
    Headache, 2007, Volume: 47, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Carotid Arteries; Epinephrine; Estradiol; Female; Imidazoles; Mi

2007
Reduced threshold for cortical spreading depression in female mice.
    Annals of neurology, 2007, Volume: 61, Issue:6

    Topics: Animals; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; El

2007
The calcium antagonist properties of cyproheptadine: implications for antimigraine action.
    Neurology, 1984, Volume: 34, Issue:3

    Topics: Animals; Basilar Artery; Calcium Channel Blockers; Calcium Chloride; Cyproheptadine; Dogs; Female; M

1984
Spreading depression can be restricted to distinct depths of the rat cerebral cortex.
    Neuroscience letters, 1993, Apr-02, Volume: 152, Issue:1-2

    Topics: Animals; Cerebral Cortex; Cortical Spreading Depression; Male; Migraine Disorders; Potassium Chlorid

1993
Sensitization of meningeal sensory neurons and the origin of headaches.
    Nature, 1996, Dec-12, Volume: 384, Issue:6609

    Topics: Animals; Autacoids; Capsaicin; Dura Mater; Electric Stimulation; Electrophysiology; Headache; Hydrog

1996
Repetitive cortical spreading depression in a gyrencephalic feline brain: inhibition by the novel benzoylamino-benzopyran SB-220453.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:6

    Topics: Analgesics; Animals; Anticonvulsants; Benzamides; Benzopyrans; Cats; Cortical Spreading Depression;

2000
Cortical spreading depression produces increased cGMP levels in cortex and brain stem that is inhibited by tonabersat (SB-220453) but not sumatriptan.
    Brain research, 2001, Feb-09, Volume: 891, Issue:1-2

    Topics: Analgesics; Animals; Benzamides; Benzopyrans; Brain Stem; Cerebral Cortex; Cortical Spreading Depres

2001
New possibilities for anti-migraine drugs: prostanoid antagonists and progesterone-mimicking stabilizers of excitable cells.
    Drug design and delivery, 1989, Volume: 4, Issue:2

    Topics: Arteries; Brain; Estradiol; Humans; Mefenamic Acid; Migraine Disorders; Muscle, Smooth, Vascular; Ne

1989