Page last updated: 2024-11-02

potassium chloride and Insulinoma

potassium chloride has been researched along with Insulinoma in 26 studies

Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
"In order to study the role of arachidonic acid (AA) in depolarization-induced insulin secretion rat insulinoma cells (RINm5F) were depleted of AA by cultivation in essential fatty acid-free medium."3.68Insulin secretion without the participation of arachidonic acid. ( Ammon, HP; Koopmann, I; Safayhi, H, 1993)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's12 (46.15)18.2507
2000's9 (34.62)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luppi, P1
Drain, P1
Mayer, SI1
Thiel, G1
Cui, X1
Yang, G1
Pan, M1
Zhang, XN1
Yang, SN1
Bernal-Mizrachi, E1
Wen, W1
Shornick, M1
Permutt, MA1
Merglen, A1
Theander, S1
Rubi, B1
Chaffard, G1
Wollheim, CB1
Maechler, P1
Matsumoto, K1
Fukunaga, K1
Miyazaki, J1
Shichiri, M1
Miyamoto, E1
Montrose-Rafizadeh, C1
Egan, JM1
Roth, J1
Safayhi, H2
Koopmann, I2
Ammon, HP5
Sher, E2
Codignola, A2
Rogers, M2
Richmond, J1
Heurich, RO1
Kolb, HA1
Lang, F1
Schaich, R1
Drews, G1
Leiers, T1
Weinhaus, AJ1
Poronnik, P1
Tuch, BE1
Cook, DI1
Stickle, D1
Ramanadham, S1
Turk, J1
Himmel, HM1
Meyer zu Heringdorf, D1
Windorfer, B1
van Koppen, CJ1
Ravens, U1
Jakobs, KH1
Wahl, MA2
Wilson, JR1
Biden, TJ1
Ludowyke, RI1
Passafaro, M1
Cooke, I1
Vajna, R1
Klöckner, U1
Pereverzev, A1
Weiergräber, M1
Chen, X1
Miljanich, G1
Klugbauer, N1
Hescheler, J1
Perez-Reyes, E1
Schneider, T1
Bihlmayer, A1
Tajiri, Y1
Grill, V1
Beffy, P1
Lajoix, AD1
Masiello, P1
Dietz, S1
Péraldi-Roux, S1
Chardès, T1
Ribes, G1
Gross, R1
Leung, YM1
Sheu, L1
Kwan, E1
Wang, G1
Tsushima, R1
Gaisano, H1
Roenfeldt, M1
Murakami, M1
Ishizuka, J1
Sumi, S1
Nickols, GA1
Cooper, CW1
Townsend, CM1
Thompson, JC1
Yada, T1
Russo, LL1
Sharp, GW2
Chertow, BS1
Moore, MR1
Blaner, WS1
Wilford, MR1
Cordle, MB1
Hoenig, M1

Other Studies

26 other studies available for potassium chloride and Insulinoma

ArticleYear
Autocrine C-peptide mechanism underlying INS1 beta cell adaptation to oxidative stress.
    Diabetes/metabolism research and reviews, 2014, Volume: 30, Issue:7

    Topics: Adaptation, Physiological; Animals; Apoptosis; Autocrine Communication; C-Peptide; Cell Line, Tumor;

2014
Calcium influx into MIN6 insulinoma cells induces expression of Egr-1 involving extracellular signal-regulated protein kinase and the transcription factors Elk-1 and CREB.
    European journal of cell biology, 2009, Volume: 88, Issue:1

    Topics: Animals; Calcium; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Dual Specificity Ph

2009
Akt signals upstream of L-type calcium channels to optimize insulin secretion.
    Pancreas, 2012, Volume: 41, Issue:1

    Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Ionophores

2012
Activation of nuclear factor-kappaB by depolarization and Ca(2+) influx in MIN6 insulinoma cells.
    Diabetes, 2002, Volume: 51 Suppl 3

    Topics: Animals; Calcium; Electrophysiology; Enzyme Inhibitors; Flavonoids; Glucose; I-kappa B Proteins; Ins

2002
Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.
    Endocrinology, 2004, Volume: 145, Issue:2

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Differentiation; Cell Division; Cytosol; Diazoxide; E

2004
Ca2+/calmodulin-dependent protein kinase II and synapsin I-like protein in mouse insulinoma MIN6 cells.
    Endocrinology, 1995, Volume: 136, Issue:9

    Topics: Animals; Autoradiography; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Electrophoresis, Po

1995
Incretin hormones regulate glucose-dependent insulin secretion in RIN 1046-38 cells: mechanisms of action.
    Endocrinology, 1994, Volume: 135, Issue:2

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Gastric Inhibitory Polypeptide; Glucagon; Glucag

1994
Insulin secretion without the participation of arachidonic acid.
    Molecular and cellular endocrinology, 1993, Volume: 91, Issue:1-2

    Topics: Alanine; Animals; Arachidonic Acid; Calcimycin; Calcium; Cell Division; Insulin; Insulin Secretion;

1993
Noradrenaline inhibition of Ca2+ channels and secretion in single patch-clamped insulinoma cells.
    FEBS letters, 1996, May-06, Volume: 385, Issue:3

    Topics: Animals; Calcium; Calcium Channels; Electrophysiology; Exocytosis; Insulinoma; Ionomycin; Ionophores

1996
The phosphatase inhibitor okadaic acid blocks KCl-depolarization-induced rise of cytosolic calcium of rat insulinoma cells (RINm5F).
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:2

    Topics: Animals; Calcium; Enzyme Inhibitors; Insulin; Insulin Secretion; Insulinoma; Membrane Potentials; Ok

1996
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
    Diabetologia, 1997, Volume: 40, Issue:4

    Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion;

1997
Effects of arachidonyltrifluoromethyl ketone on cytosolic [Ca2+] in HIT insulinoma cells.
    Journal of lipid mediators and cell signalling, 1997, Volume: 17, Issue:1

    Topics: Animals; Arachidonic Acids; Calcium; Cytosol; Enzyme Inhibitors; Insulinoma; Islets of Langerhans; P

1997
Guanine nucleotide-sensitive inhibition of L-type Ca2+ current by lysosphingolipids in RINm5F insulinoma cells.
    Molecular pharmacology, 1998, Volume: 53, Issue:5

    Topics: Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Gu

1998
Oxidative stress causes depolarization and calcium uptake in the rat insulinoma cell RINm5F.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1998, Volume: 106, Issue:3

    Topics: Animals; Calcium; Cell Survival; Cytosol; Electrophysiology; Glutathione; Insulin; Insulin Secretion

1998
Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells.
    Diabetes, 1999, Volume: 48, Issue:12

    Topics: Animals; Cells, Cultured; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Myosin Heavy

1999
Modulation of N-type calcium channels translocation in RINm5F insulinoma cells.
    Pharmacological research, 2000, Volume: 41, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Cadmium; Calcium; Calcium Channels, N-Type; Drug Interactions;

2000
Functional coupling between 'R-type' Ca2+ channels and insulin secretion in the insulinoma cell line INS-1.
    European journal of biochemistry, 2001, Volume: 268, Issue:4

    Topics: Alternative Splicing; Animals; Barium; Calcium Channel Blockers; Calcium Channels; Calcium Channels,

2001
Distribution and stimulation by gastrin-releasing peptide of protein kinase C subfamilies in insulin-secreting cells.
    Neuroendocrinology, 2001, Volume: 73, Issue:5

    Topics: Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Female; Gastrin-Releasing Peptide;

2001
Aminoguanidine exerts a beta-cell function-preserving effect in high glucose-cultured beta-cells (INS-1).
    International journal of experimental diabetes research, 2000, Volume: 1, Issue:2

    Topics: Animals; Cell Line; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Guanidine

2000
A constitutive nitric oxide synthase modulates insulin secretion in the INS-1 cell line.
    Molecular and cellular endocrinology, 2001, Oct-25, Volume: 183, Issue:1-2

    Topics: Animals; Arginine; Enzyme Inhibitors; Glucose; Insulin; Insulin Secretion; Insulinoma; Isoenzymes; M

2001
Visualization of sequential exocytosis in rat pancreatic islet beta cells.
    Biochemical and biophysical research communications, 2002, Apr-12, Volume: 292, Issue:4

    Topics: Animals; Cell Membrane; Cells, Cultured; Exocytosis; Fluorescent Dyes; Glucose; Insulin; Insulin Sec

2002
KCl-induced insulin secretion from RINm5F cells is mediated through Ca2+ influx along L-type Ca2+ channels.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:5

    Topics: Animals; Calcium; Calcium Channels; Diltiazem; Insulin; Insulin Secretion; Insulinoma; Isradipine; K

1992
Role of extracellular magnesium in insulin secretion from rat insulinoma cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 200, Issue:4

    Topics: Animals; Calcium; Cell Line; Colforsin; Glyburide; Glyceraldehyde; Insulin; Insulin Secretion; Insul

1992
Phorbol ester-stimulated insulin secretion by RINm5F insulinoma cells is linked with membrane depolarization and an increase in cytosolic free Ca2+ concentration.
    The Journal of biological chemistry, 1989, Feb-15, Volume: 264, Issue:5

    Topics: Adenoma, Islet Cell; Animals; Benzofurans; Calcium; Carbachol; Cell Line; Cell Membrane; Cytosol; Et

1989
Cytoplasmic retinoid-binding proteins and retinoid effects on insulin release in RINm5F beta-cells.
    Diabetes, 1989, Volume: 38, Issue:12

    Topics: Animals; Carrier Proteins; Cell Line; Insulin; Insulin Secretion; Insulinoma; Kinetics; Neoplasm Pro

1989
Glucose induces insulin release and a rise in cytosolic calcium concentration in a transplantable rat insulinoma.
    Endocrinology, 1986, Volume: 119, Issue:6

    Topics: Adenoma, Islet Cell; Aminoquinolines; Animals; Calcium; Carbachol; Cytosol; Dose-Response Relationsh

1986