potassium chloride has been researched along with Hypertension in 424 studies
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/day and potassium chloride was compared with that of enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension." | 9.12 | Efficacy and safety of 24 weeks of therapy with bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride compared with enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension : a multicentre, randomis ( Borrild, N; Rasmussen, S; Vang Andersen, J, 2006) |
| "The effects of 5 mg bendroflumethiazide plus 15 mmol potassium chloride versus 50 mg hydrochlorothiazide plus 5 mg amiloride on blood pressure and serum electrolytes were investigated in a 12-week, open, randomized study with parallel treatment groups." | 9.06 | The effects of bendroflumethiazide/potassium chloride versus hydrochlorothiazide/amiloride on blood pressure and serum electrolytes in patients with mild to moderate hypertension seen in general practice. ( Bredesgaard, P; Johansen, P; Jørgensen, F, 1986) |
| "25 mg cyclopenthiazide plus 600 mg potassium chloride ('Navidrex' K) in the treatment of mild to moderate essential hypertension." | 9.05 | Comparative clinical trial of bemetizide/triamterene and cyclopenthiazide/potassium chloride combinations in patients with mild to moderate hypertension. ( Benton, KG; Weener, W; Whitehill, D; Whittington, JR; Wray, R; Wright, B, 1983) |
| "Potassium chloride was compared with triamterene in a crossover trial involving 16 hypertensive patients with overt diuretic-induced hypokalemia." | 9.05 | Effectiveness of potassium chloride or triamterene in thiazide hypokalemia. ( Burris, J; Freis, ED; Kukich, S; Papademetriou, V, 1985) |
| "A randomized, double-blind, cross-over study comparing 50 mg hydrochlorothiazide plus 5 mg amiloride (HCTZ/A) with 50 mg hydrochlorothiazide plus 26 mmol potassium chloride (HCTZ/K) was conducted in 18 patients with mild essential hypertension (diastolic pressure 90-105 mmHg)." | 9.05 | Hydrochlorothiazide and potassium chloride in comparison with hydrochlorothiazide and amiloride in the treatment of mild hypertension. ( Andersen, B; Hardarson, T; Ragnarsson, J; Snorrason, SP, 1985) |
| "Twenty patients with mild or moderate essential hypertension and not receiving any drug treatment, who had been moderately restricting their sodium intake to around 70 mmol(mEq) a day for at least one month and whose mean blood pressure was then 163/103 mm Hg, were entered into a double blind, randomised crossover study to compare one month's treatment with slow release potassium chloride tablets (64 mmol potassium chloride a day) with one month's treatment with a matching placebo." | 9.05 | Moderate potassium chloride supplementation in essential hypertension: is it additive to moderate sodium restriction? ( MacGregor, GA; Markandu, ND; Sagnella, GA; Smith, SJ, 1985) |
| "Two hundred and thirty-eight patients with essential hypertension from 39 general practice centres were treated in a double-blind trial with either oxprenolol 160 mg in a slow-release (SR) formulation with cyclopenthiazide 0,25 mg and potassium chloride 600 mg given once daily, or methyldopa 250 mg 3 times daily." | 9.04 | Oxprenolol slow-release with cyclopenthiazide-KCl compared with methyldopa in the treatment of essential hypertension. A multicentre general practice trial. ( Levenstein, JH, 1978) |
| "Here we investigated cinnamaldehyde (CA) effect on diabetes-induced hypertension." | 7.77 | Cinnamaldehyde protects from the hypertension associated with diabetes. ( Badawy, D; El-Bassossy, HM; Fahmy, A, 2011) |
| "Losartan treatment prevents the development of hypertension but not all vascular changes observed after ouabain treatment." | 7.72 | Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries. ( Alonso, MJ; Balfagón, G; Rossoni, LV; Salaices, M; Vassallo, DV; Xavier, FE, 2004) |
| "Functional and morphological changes of blood vessels in cyclosporine A (CsA)-induced hypertension and nephrotoxicity were studied in spontaneously hypertensive rats (SHR)." | 7.71 | Vascular changes in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet. ( Finckenberg, P; Lassila, M; Moilanen, E; Nurminen, ML; Riutta, A; Salmenperä, P; Santisteban, J; Vapaatalo, H; Virtanen, I, 2001) |
| " Salt-sensitive (DS) and salt-resistant (DR) Dahl rats were treated with a high-sodium diet (NaCl 4%) with or without ET(A) receptor antagonist LU135252 for two months, and effects of treatments on systolic blood pressure, vascular endothelin-1 (ET-1) protein content, aortic hypertrophy, and vascular reactivity of isolated aortic rings were studied." | 7.70 | ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension. ( Barton, M; d'Uscio, LV; Lüscher, TF; Meyer, P; Moreau, P; Shaw, S, 1998) |
| " Since endothelin-1 is a potent vasoconstrictor putatively involved in hypertension, we have compared the contractile responses of endothelin-1 and noradrenaline in relation to potassium chloride in subcutaneous resistance arteries from subjects with established essential hypertension with matched controls." | 7.70 | Selective increase of the contractile response to endothelin-1 in subcutaneous arteries from patients with essential hypertension. ( Adner, M; Brunkwall, J; Edvinsson, L; Erlinge, D; Lind, H, 1999) |
| "The present study evaluates the response to the L-type voltage gated calcium channel agonist Bay K 8644 in two forms of experimental hypertension (mineralocorticoid- and hypertension induced by the nitric oxide synthase inhibitor N omega-nitro-L-arginine (N-Nitro arginine)) and under conditions of acute stretch." | 7.69 | Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension. ( Finta, KM; Lloyd, MC; Storm, DS; Watts, SW; Webb, RC, 1994) |
| "Paeonol is a Chinese herbal monomer extracted from Cortex moutan, exhibited some anti-hypertensive activity." | 5.72 | New paeonol derivative C302 reduces hypertension in spontaneously hypertensive rats through endothelium-dependent and endothelium-independent vasodilation. ( Bai, TT; Cao, HL; Chen, YL; He, CX; Li, AH; Li, HJ; Li, L; Li, PQ; Liu, JL; Liu, YX; Qin, W; Su, XL; Wang, JK; Wang, M; Wu, SP; Xing, L; Zhao, D; Zhou, X, 2022) |
| "Glycyrrhizin can cause pseudohyperaldosteronism and thereby result in hypertension and hypokalaemia." | 5.48 | Potassium chloride mixture may maintain hypokalaemia and hypertension. ( Borg, R; Hansen, D; Mandoe, MJ, 2018) |
| "Rosiglitazone treatment of diabetic rats abolished the increase in diastolic BP and significantly reduced the increased systolic BP without affecting the development of hyperglycaemia." | 5.38 | Rosiglitazone, a peroxisome proliferator-activated receptor γ stimulant, abrogates diabetes-evoked hypertension by rectifying abnormalities in vascular reactivity. ( Abo-Warda, SM; El-Bassossy, HM; Fahmy, A, 2012) |
| " These studies indicate that normalization of vascular function can occur in the presence of significantly elevated blood pressure upon chronic administration of eflornithine." | 5.30 | Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. ( Aziz, SM; Lipke, DW; Newman, PS; Soltis, EE; Tofiq, S, 1997) |
| " Dose-response curves were generated in the aorta in response to potassium chloride (KCl), AII and PE." | 5.29 | Vascular reactivity to phenylephrine and angiotensin II in hypertensive rats associated with insulin resistance. ( Iyer, SN; Katovich, MJ, 1996) |
| " A total of 282 Tibetans aged 40 or older with known hypertension (systolic BP≥140 mmHg) were recruited and randomized to intervention (salt-substitute, 65% sodium chloride, 25% potassium chloride and 10% magnesium sulfate) or control (100% sodium chloride) in a 1: 1 allocation ratio with three months' supply." | 5.19 | Using a low-sodium, high-potassium salt substitute to reduce blood pressure among Tibetans with high blood pressure: a patient-blinded randomized controlled trial. ( He, F; Ke, L; Lam, CT; Li, S; Li, X; Luobu, G; Sang, B; Wu, Y; Xie, W; Yan, LL; Yin, X; Zhao, X, 2014) |
| "5 mg/day and potassium chloride was compared with that of enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension." | 5.12 | Efficacy and safety of 24 weeks of therapy with bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride compared with enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension : a multicentre, randomis ( Borrild, N; Rasmussen, S; Vang Andersen, J, 2006) |
| "The effects of 5 mg bendroflumethiazide plus 15 mmol potassium chloride versus 50 mg hydrochlorothiazide plus 5 mg amiloride on blood pressure and serum electrolytes were investigated in a 12-week, open, randomized study with parallel treatment groups." | 5.06 | The effects of bendroflumethiazide/potassium chloride versus hydrochlorothiazide/amiloride on blood pressure and serum electrolytes in patients with mild to moderate hypertension seen in general practice. ( Bredesgaard, P; Johansen, P; Jørgensen, F, 1986) |
| "25 mg cyclopenthiazide plus 600 mg potassium chloride ('Navidrex' K) in the treatment of mild to moderate essential hypertension." | 5.05 | Comparative clinical trial of bemetizide/triamterene and cyclopenthiazide/potassium chloride combinations in patients with mild to moderate hypertension. ( Benton, KG; Weener, W; Whitehill, D; Whittington, JR; Wray, R; Wright, B, 1983) |
| " To assess the effect of potassium repletion in hypokalemic hypertension, we administered either potassium chloride, 60 mmol per day, or placebo tablets, each for six weeks, in a randomized, double-blind, crossover trial to 16 hypertensive patients who had diuretic-induced hypokalemia and who continued to take a constant amount of diuretic." | 5.05 | Potassium supplementation in hypertensive patients with diuretic-induced hypokalemia. ( Carnegie, A; Heller, JA; Kaplan, NM; Raskin, P; Simmons, M, 1985) |
| "To determine the effects of potassium on blood pressure and factors affecting blood pressure, we conducted a randomized, placebo controlled trial of a potassium chloride-based substitute for table salt in 23 patients with mild to moderate essential hypertension." | 5.05 | Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure. ( Barnett, P; Cumming, AM; Hutcheson, MJ; Semple, PF; Zoccali, C, 1985) |
| "Potassium chloride was compared with triamterene in a crossover trial involving 16 hypertensive patients with overt diuretic-induced hypokalemia." | 5.05 | Effectiveness of potassium chloride or triamterene in thiazide hypokalemia. ( Burris, J; Freis, ED; Kukich, S; Papademetriou, V, 1985) |
| "A randomized, double-blind, cross-over study comparing 50 mg hydrochlorothiazide plus 5 mg amiloride (HCTZ/A) with 50 mg hydrochlorothiazide plus 26 mmol potassium chloride (HCTZ/K) was conducted in 18 patients with mild essential hypertension (diastolic pressure 90-105 mmHg)." | 5.05 | Hydrochlorothiazide and potassium chloride in comparison with hydrochlorothiazide and amiloride in the treatment of mild hypertension. ( Andersen, B; Hardarson, T; Ragnarsson, J; Snorrason, SP, 1985) |
| "Twenty patients with mild or moderate essential hypertension and not receiving any drug treatment, who had been moderately restricting their sodium intake to around 70 mmol(mEq) a day for at least one month and whose mean blood pressure was then 163/103 mm Hg, were entered into a double blind, randomised crossover study to compare one month's treatment with slow release potassium chloride tablets (64 mmol potassium chloride a day) with one month's treatment with a matching placebo." | 5.05 | Moderate potassium chloride supplementation in essential hypertension: is it additive to moderate sodium restriction? ( MacGregor, GA; Markandu, ND; Sagnella, GA; Smith, SJ, 1985) |
| "Two hundred and thirty-eight patients with essential hypertension from 39 general practice centres were treated in a double-blind trial with either oxprenolol 160 mg in a slow-release (SR) formulation with cyclopenthiazide 0,25 mg and potassium chloride 600 mg given once daily, or methyldopa 250 mg 3 times daily." | 5.04 | Oxprenolol slow-release with cyclopenthiazide-KCl compared with methyldopa in the treatment of essential hypertension. A multicentre general practice trial. ( Levenstein, JH, 1978) |
| "The relative efficacies of potassium chloride, amiloride, triamterene and spironolactone in maintaining potassium balance were studied in 40 patients with essential hypertension receiving diuretic therapy." | 5.04 | Maintenance of potassium balance during diuretic therapy. ( Eisalo, A; Kohvakka, A; Manninen, V, 1979) |
| "Ouabain is an endogenous Na(+)/K(+)-ATPase inhibitor whose chronic administration induces hypertension." | 3.81 | Chronic ouabain treatment induces Rho kinase activation. ( Ark, M; Aypar, E; Demirtaş, A; Gözübüyük, G; Ozdemir, A; Şahan, G; Turan, NN, 2015) |
| "Here we investigated cinnamaldehyde (CA) effect on diabetes-induced hypertension." | 3.77 | Cinnamaldehyde protects from the hypertension associated with diabetes. ( Badawy, D; El-Bassossy, HM; Fahmy, A, 2011) |
| " Hydrogen sulfide (H(2)S) is a prominent EDRF, since mice lacking its biosynthetic enzyme, cystathionine γ-lyase (CSE), display pronounced hypertension with deficient vasorelaxant responses to acetylcholine." | 3.77 | Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels. ( Amzel, LM; Barodka, VM; Barrow, RK; Berkowitz, DE; Bhunia, AK; Gazi, FK; Gazi, SK; Jung, SM; Mustafa, AK; Sikka, G; Snyder, SH; Steppan, J; Wang, R, 2011) |
| "SOD-mediated vasorelaxation may contribute to the chronic antihypertensive effect and/or the improvement in insulin sensitivity following pioglitazone treatment." | 3.76 | Pioglitazone improves superoxide dismutase mediated vascular reactivity in the obese Zucker rat. ( Bryer-Ash, M; Dorafshar, AH; Khoe, M; Lyon, C; Moodley, K, 2010) |
| " Nutritional interventions, like potassium chloride (KCl) diet supplementation, and exercises are common nonpharmacological indications for treating hypertension." | 3.76 | Evaluation of exercise and potassium chloride supplementation on blood pressure and nociceptive threshold in hypertensive rats. ( Duarte, ID; Franca, VM; Galdino, GS; Lopes, AM; Perez, AC, 2010) |
| "We reported previously that simulating sleep apnea in rats by exposing them 7 hours per day to intermittent hypoxia/hypercapnia (IH) elevates plasma endothelin-1 and causes hypertension, which is reversed by an endothelin-1 antagonist." | 3.73 | Augmented endothelin vasoconstriction in intermittent hypoxia-induced hypertension. ( Allahdadi, KJ; Kanagy, NL; Walker, BR, 2005) |
| "Losartan treatment prevents the development of hypertension but not all vascular changes observed after ouabain treatment." | 3.72 | Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries. ( Alonso, MJ; Balfagón, G; Rossoni, LV; Salaices, M; Vassallo, DV; Xavier, FE, 2004) |
| "Functional and morphological changes of blood vessels in cyclosporine A (CsA)-induced hypertension and nephrotoxicity were studied in spontaneously hypertensive rats (SHR)." | 3.71 | Vascular changes in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet. ( Finckenberg, P; Lassila, M; Moilanen, E; Nurminen, ML; Riutta, A; Salmenperä, P; Santisteban, J; Vapaatalo, H; Virtanen, I, 2001) |
| "Low levels of lead, but not high levels, produce hypertension." | 3.71 | Influence of lead on rat thoracic aorta contraction and relaxation. ( Gonick, HC; Shelkovnikov, SA, 2001) |
| " Inhibition of 11beta-HSD2 by liquorice-derived glycyrrhizic acid (GA) therefore results in sodium retention and hypertension." | 3.71 | Influence of aldosterone vs. endothelin receptor antagonism on renovascular function in liquorice-induced hypertension. ( Christ, M; Lunt, CM; Lüscher, TF; Niggli, B; Quaschning, T; Ruschitzka, F; Shaw, S; Wehling, M, 2001) |
| "To identify the receptors by which endothelin-1 (ET-1) increases venomotor tone in hypertension." | 3.71 | Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt-hypertensive rats. ( Fink, GD; Galligan, JJ; Johnson, RJ; Watts, SW, 2002) |
| " Salt-sensitive (DS) and salt-resistant (DR) Dahl rats were treated with a high-sodium diet (NaCl 4%) with or without ET(A) receptor antagonist LU135252 for two months, and effects of treatments on systolic blood pressure, vascular endothelin-1 (ET-1) protein content, aortic hypertrophy, and vascular reactivity of isolated aortic rings were studied." | 3.70 | ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension. ( Barton, M; d'Uscio, LV; Lüscher, TF; Meyer, P; Moreau, P; Shaw, S, 1998) |
| "Endothelin-1 (ET-1) is thought to play an important role in the development of deoxycorticosterone acetate (DOCA)-salt hypertension." | 3.70 | Coronary vascular reactivity is improved by endothelin A receptor blockade in DOCA-salt hypertensive rats. ( Clarke, N; Fuchs, LC; Giulumian, AD; Pollock, DM, 1998) |
| " Since endothelin-1 is a potent vasoconstrictor putatively involved in hypertension, we have compared the contractile responses of endothelin-1 and noradrenaline in relation to potassium chloride in subcutaneous resistance arteries from subjects with established essential hypertension with matched controls." | 3.70 | Selective increase of the contractile response to endothelin-1 in subcutaneous arteries from patients with essential hypertension. ( Adner, M; Brunkwall, J; Edvinsson, L; Erlinge, D; Lind, H, 1999) |
| " This study analyses the contribution of the precursor L-arginine (L-arg) by oral administration in two kidney-two clip hypertension in the rat (2K-2C)." | 3.70 | Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats. ( Albornoz, LE; Damiano, PF; de la Riva, IJ; Ferrero, AJ; Palumbo, EL; Rosón, MI; Speziale, N; Vega, GW, 2000) |
| "The present study evaluates the response to the L-type voltage gated calcium channel agonist Bay K 8644 in two forms of experimental hypertension (mineralocorticoid- and hypertension induced by the nitric oxide synthase inhibitor N omega-nitro-L-arginine (N-Nitro arginine)) and under conditions of acute stretch." | 3.69 | Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension. ( Finta, KM; Lloyd, MC; Storm, DS; Watts, SW; Webb, RC, 1994) |
| " In order to investigate further whether the increased sensitivity to inhibition by nifedipine of the responses to noradrenaline of aortae from spontaneously hypertensive stroke-prone (SHRSP) rats is related to the development of the hypertension, we have compared the sensitivity to noradrenaline, potassium chloride (KCl) and nifedipine of aortae from SHRSP and control (Wistar-Kyoto) WKY rats of different age groups (young: 3-5 weeks, and adult: 13-16 weeks)." | 3.69 | The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age. ( Iwanov, V; Jiang, GC; Moulds, RF, 1995) |
| " In this study we tested whether an augmented Ca2+ responsiveness of smooth muscle myofilaments may contribute to the increased coronary tone observed in hypertension using beta-escin-permeabilized coronary arteries from 3-mo-old stroke-prone spontaneously hypertensive rats (SHRSP) and their age matched normotensive reference strain (WKY rats)." | 3.69 | Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells. ( Ganten, D; Kreutz, R; Pfitzer, G; Satoh, S; Wilm, C, 1994) |
| " Oral enalapril from weaning to 100 days of age prevented hypertension in SHR but did not impair the responsiveness of ARNA to any stimulus." | 3.68 | Age-dependent changes in afferent renal nerve activity in genetically hypertensive rats. ( Moss, NG; Scoltock, AB, 1992) |
| "In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively." | 3.67 | [Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension]. ( Barnatskiĭ, VN; Korsunskiĭ, VN; Moiseev, AA; Stoliarov, VP; Vikhrov, NI, 1984) |
| "Eight controlled 1- or 2-wk experiments involving 225 healthy male subjects and one study of 18 patients with hypertension, nine of whom were long-term users of a wax-matrix potassium chloride preparation, were conducted to evaluate the upper gastrointestinal safety of oral KCl supplements." | 3.67 | Effect of potassium chloride supplements on upper gastrointestinal mucosa. ( Akdamar, K; Ertan, A; McMahon, FG; Ryan, JR, 1984) |
| " Plasma ACTH responses to hemorrhage and ether stress were significantly smaller in 7-week-old SHR than in age-matched Wistar-Kyoto rats (WKY), while plasma corticosterone baseline levels and its response to stress were greater in SHR than in WKY." | 3.67 | Abnormalities in the hypothalamo-pituitary-adrenal axis in spontaneously hypertensive rats during development of hypertension. ( Hashimoto, K; Hirasawa, R; Makino, S; Murakami, K; Ono, K; Ota, Z; Sugawara, M; Takao, T, 1989) |
| " The potency and efficacy of isoproterenol (ISO) in these arteries were decreased in SHR before and during the development of hypertension as compared with age-matched Wistar Kyoto rats (WKY)." | 3.67 | Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension. ( Aoki, K; Asano, M; Dohi, Y; Fujimoto, S; Matsuda, T, 1987) |
| "The effect of plasma from patients with essential hypertension and from normotensive subjects on the contractile response to noradrenaline and potassium chloride has been investigated using human isolated arteries." | 3.67 | The effect of plasma from patients with essential hypertension on the contractility of human arteries. ( Cappuccio, FP; Leathard, HL; MacGregor, GA; Markandu, ND; Sagnella, GA, 1988) |
| "The reactivity of the rat popliteal, mesenteric and renal arteries and veins to electrical stimulation, noradrenaline, serotonin and potassium chloride in the DOCA-salt hypertension, was studied." | 3.67 | [Versatility of arterial and venous responses to the action of physiologic stimuli in rats with DOCA-salt hypertension]. ( Elinek, I; Govyrin, VA; Kunesh, Ia; Leont'eva, GR; Zikha, I, 1988) |
| "In order to investigate the role of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) in essential hypertension (EH), the responses of plasma 17-OH-DOC to 7 stimulation tests (furosemide test, adrenal suppression test, angiotensin II infusion test, adrenal stimulation test, metopirone test, saline infusion test and potassium chloride infusion test) and the circadian rhythm were investigated in 18 patients with essential hypertension (low renin group: 8, and normal renin group: 10)." | 3.66 | Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension. ( Den, K; Hatano, M; Honda, M; Izumi, Y; Kanbegawa, A; Oguri, K; Shiratsuchi, T; Tsuchiya, M; Ueda, Y, 1978) |
| "In the context of nonpharmacological treatment of hypertension, sodium restriction plays an important role." | 2.82 | [Can salt substitution or reduction replace pharmaceuticals for arterial hypertension?] ( Zidek, W, 2022) |
| "Hypertension was defined per World Health Organization guidelines as BP≥140/90mmHg." | 2.82 | Intake of low sodium salt substitute for 3years attenuates the increase in blood pressure in a rural population of North China - A randomized controlled trial. ( Fu, LY; Shi, JP; Wang, HL; Wang, WL; Webster, J; Wu, XM; Zhou, B, 2016) |
| " There was a significant, independent, dose-response relationship between change in both 24-hour urinary potassium excretion and urinary sodium-potassium ratio and the corresponding change in diastolic blood pressure (-1." | 2.68 | The effect of potassium supplementation in persons with a high-normal blood pressure. Results from phase I of the Trials of Hypertension Prevention (TOHP). Trials of Hypertension Prevention (TOHP) Collaborative Research Group. ( Borhani, NO; Buring, J; Cohen, JD; Cook, N; Cutler, JA; Kiley, JE; Kuller, LH; Sacks, FM; Satterfield, S; Whelton, PK, 1995) |
| " However, variability of plasma potassium within the dose interval was not increased markedly, and 12 hourly dosing is probably satisfactory for both potassium chloride and spironolactone at the doses studied." | 2.67 | Adequacy of twice daily dosing with potassium chloride and spironolactone in thiazide treated hypertensive patients. ( Brawn, LA; Ramsay, LE; Toner, JM; Yeo, WW, 1991) |
| " Furthermore, no adverse effects were noted with either potassium chloride formulation, and patient acceptance, tolerability, and compliance to prescribed dosing regimens were similar for both products." | 2.66 | Therapeutic assessment of Slow-K and K-tab potassium chloride formulations in hypertensive patients treated with thiazide diuretics. ( Acchiardo, SR; Carter, CA; Skoutakis, VA, 1987) |
| "When reserpine was withdrawn from nine women they followed a modified protocol comparing bendrofluazide and potassium chloride with potassium chloride alone." | 2.64 | Mild hypertension: a clinical trial conducted in hospital general practice. ( Garrett, RT; Joesbury, HE; Phillips, CA; Smith, AJ; Wilkes, E, 1976) |
| "The incidence of ventricular arrhythmias is proportional to the potassium deficit and may be enhanced by concomitant magnesium deficiency." | 2.37 | Diuretics, potassium depletion and the risk of arrhythmias. ( Robertson, JI, 1984) |
| "Paeonol is a Chinese herbal monomer extracted from Cortex moutan, exhibited some anti-hypertensive activity." | 1.72 | New paeonol derivative C302 reduces hypertension in spontaneously hypertensive rats through endothelium-dependent and endothelium-independent vasodilation. ( Bai, TT; Cao, HL; Chen, YL; He, CX; Li, AH; Li, HJ; Li, L; Li, PQ; Liu, JL; Liu, YX; Qin, W; Su, XL; Wang, JK; Wang, M; Wu, SP; Xing, L; Zhao, D; Zhou, X, 2022) |
| "Glycyrrhizin can cause pseudohyperaldosteronism and thereby result in hypertension and hypokalaemia." | 1.48 | Potassium chloride mixture may maintain hypokalaemia and hypertension. ( Borg, R; Hansen, D; Mandoe, MJ, 2018) |
| "Hypertension is the most common risk factor for stroke, coronary heart disease and heart failure, which are the leading causes of death worldwide." | 1.46 | Lecithin derived from ω-3 PUFA fortified eggs decreases blood pressure in spontaneously hypertensive rats. ( Bobak, Ł; Martynowicz, H; Nowacki, D; Skoczyńska, A; Szuba, A; Trziszka, T; Turczyn, B; Wojakowska, A, 2017) |
| "Hypertension is a public health problem and increases the incidence of cardiovascular diseases." | 1.42 | Effects of one resistance exercise session on vascular smooth muscle of hypertensive rats. ( Araújo, JE; Bonjardim, LR; Fontes, MT; Mota, MM; Oliveira Carvalho, V; Santos, MR; Silva, TL, 2015) |
| "widely used in southeastern Asia for treating hypertension." | 1.42 | Vasodilatory Effect of Wogonin on the Rat Aorta and Its Mechanism Study. ( Chen, L; Gao, XM; Geng, X; Li, CX; Liu, F; Ma, YK; Mao, HP; Qiu, LZ; Qu, JT; Wang, H; Yang, Y; Zhang, DX; Zhang, JM, 2015) |
| "Hypokalemic hypertension is a common condition leading to the diagnosis of secondary hypertension." | 1.38 | Polycystic kidney disease presenting with hypertension and hypokalemia. ( Chow, KM; Li, PK; Ma, RC; Szeto, CC, 2012) |
| "Rosiglitazone treatment of diabetic rats abolished the increase in diastolic BP and significantly reduced the increased systolic BP without affecting the development of hyperglycaemia." | 1.38 | Rosiglitazone, a peroxisome proliferator-activated receptor γ stimulant, abrogates diabetes-evoked hypertension by rectifying abnormalities in vascular reactivity. ( Abo-Warda, SM; El-Bassossy, HM; Fahmy, A, 2012) |
| "Hypokalemia is common and can be associated with serious adverse consequences, including paralysis, ileus, cardiac arrhythmias, and death." | 1.38 | A physiologic-based approach to the treatment of a patient with hypokalemia. ( Asmar, A; Mohandas, R; Wingo, CS, 2012) |
| "Aldosterone treatment did not modify NO or TxB(2) release, but it did increase superoxide anion and 6-keto-PGF(1alpha) release in mesenteric resistance arteries from both strains." | 1.37 | Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats. ( Avendaño, MS; Balfagón, G; Blanco-Rivero, J; Salaíces, M; Sastre, E; Velázquez, K; Xavier, FE; Yela, R, 2011) |
| "Amlodipine treatment reduced the contractions and improved relaxation to ACh." | 1.37 | Amlodipine ameliorates endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats. ( Cheng, G; He, X; Jiang, HK; Li, DL; Sun, L; Yang, JL; Yu, XJ; Zang, WJ; Zhang, HL; Zhao, M; Zhao, Q, 2011) |
| "Hypertension was induced by biweekly subcutaneous injections of 50mg/kg DOCA plus 1% NaCl in drinking water." | 1.36 | Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in rats. ( Chen, YY; Du, JR; He, Y; Ji, W; Li, DS; Qiao, KY; Yu, CX; Yu, DK; Zhao, CY, 2010) |
| "Approximately 40% of patients with type 2 diabetes present with concurrent hypertension at the time of diabetes diagnosis." | 1.35 | Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension. ( Behnke, BJ; Delp, MD; Donato, AJ; Laughlin, MH; Lesniewski, LA; Ray, CA; Woodman, CR, 2008) |
| "Pretreatment with flavone enhanced relaxant effects to endothelium-dependent vasodilator acetylcholine (ACh) and attenuated contractile effects to alpha(1)-receptor agonist phenylephrine (PE) in WKY aortae compared to those observed in control aortic rings." | 1.34 | Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid. ( Achike, FI; Ajay, M; Mustafa, MR, 2007) |
| " The dose-response curves to NE and AVP obtained in isolated perfused kidneys from castrated SHRs were displaced to the right of those obtained in sham-operated and castrated + testosterone-treated SHRs." | 1.33 | Rho kinase contributes to androgen amplification of renal vasoconstrictor responses in the spontaneously hypertensive rat. ( Martin, DS; Song, J, 2006) |
| "Essential hypertension is associated with several alterations in arterial function." | 1.33 | Increased wall tension in response to vasoconstrictors in isolated mesenteric arterial rings from patients with high blood pressure. ( Kähönen, M; Kööbi, P; Mäki-Jouppi, J; Mustonen, J; Nordback, I; Pörsti, I; Sand, J; Tahvanainen, A; Taurio, J, 2006) |
| "Potassium chloride did not lower blood pressure (BP) in either group (P >." | 1.32 | Diminished renal kallikrein responses to mineralocorticoid stimulation in African Americans: determinants of an intermediate phenotype for hypertension. ( Kailasam, MT; Martinez, JA; O'Connor, DT; Parmer, RJ; Wong, CM, 2003) |
| "Quercetin and verapamil treatments reduced the endothelium-independent hyper-reactivity to KCl observed in the aorta of DOCA-salt-hypertensive rats, but only quercetin increased the contractile responses to angiotensin II, improved endothelial dysfunction and restored basal aortic Cu/Zn SOD expression, altered in DOCA-salt-treated rats." | 1.32 | Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil. ( Duarte, J; Galisteo, M; García-Saura, MF; Jiménez, R; Vargas, F; Villar, IC; Wangensteen, R; Zarzuelo, A, 2004) |
| " These studies indicate that normalization of vascular function can occur in the presence of significantly elevated blood pressure upon chronic administration of eflornithine." | 1.30 | Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. ( Aziz, SM; Lipke, DW; Newman, PS; Soltis, EE; Tofiq, S, 1997) |
| "Mefenamic acid was without effect on ACh-induced relaxations in either the arterial or the venous beds from WKY and SHR." | 1.30 | Comparison of the nitric oxide and cyclo-oxygenase pathway in mesenteric resistance vessels of normotensive and spontaneously hypertensive rats. ( Finet, M; Le Marquer-Domagala, F, 1997) |
| "Verapamil and veratran were more effective than trandolapril at reducing lamina media cross-sectional area." | 1.30 | Antihypertensive action of trandolapril and verapamil in spontaneously hypertensive rats after unilateral nephrectomy. ( Carrón, R; Flores, O; López-Hernández, FJ; López-Novoa, JM; Montero, MJ, 1998) |
| "The mean birth weight was 2370 +/- 614 g (range 1510-3250 g)." | 1.30 | A 3 year, prospectively-designed study of late selective multifetal pregnancy reduction. ( Amit, A; Amster, R; Geva, E; Hartoov, J; Jaffa, A; Lerner-Geva, L; Lessing, JB; Wolman, I, 1998) |
| "Pretreatment with indomethacin enhanced the relaxation response to acetylcholine in only SHRs at ages 16-20 and 55-60 weeks, thereby cancelling the difference in the relaxation response between WKY rats and SHRs." | 1.30 | Nitric oxide-dependent vasodilator mechanism is not impaired by hypertension but is diminished with aging in the rat aorta. ( Imaoka, Y; Kamada, T; Mio, Y; Okumura, K; Osanai, T; Satoh, K, 1999) |
| "potassium chloride were considered as functional indices for evaluation of neuronal Na(+)-pump activity in 8 and 12 week old (8 wk and 12 wk) SHR, WKY and Sprague-Dawley (SD) rats." | 1.29 | Age-dependent alterations in Na+, K(+)-ATPase activity in the central nervous system of spontaneously hypertensive rats: relationship to the development of high blood pressure. ( Jandhyala, BS; Shah, J, 1995) |
| " Cocaine produced a shift to the left of the norepinephrine dose-response in vessels from both controls and hypertensive patients." | 1.29 | Morphology of resistance arteries and comparison of effects of vasoconstrictors in mild essential hypertensive patients. ( Deng, LY; Larochelle, P; Schiffrin, EL, 1993) |
| "Portal hypertension was induced by partial portal vein ligation (PVL)." | 1.29 | Vascular hyporesponsiveness in aorta from portal hypertensive rats: possible sites of involvement. ( Chang, SP; Hong, CY; Huang, YT; Lin, HC; Wang, GF; Yang, MC, 1996) |
| " Dose-response curves were generated in the aorta in response to potassium chloride (KCl), AII and PE." | 1.29 | Vascular reactivity to phenylephrine and angiotensin II in hypertensive rats associated with insulin resistance. ( Iyer, SN; Katovich, MJ, 1996) |
| " In conclusion, isolated mesenteric arteries from obese Zucker rats do not show relevant structural changes, and the pharmacodynamic behaviour of such vessels appears to be the same as that of control preparations." | 1.29 | Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats. ( Kam, KL; Pfaffendorf, M; van Zwieten, PA, 1996) |
| " Tolerance of the antihypertensive effect of TC-81 in long-term daily dosing and the rebound phenomenon after discontinuance of the treatment were not observed in hypertensive rats." | 1.28 | Antihypertensive effect of the new calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl-methyl-4-(2-fluoro-5- nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate hydrochloride in rats. ( Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Sunakawa, K; Takeshita, T; Tanabe, H, 1992) |
| " In SHR the dose-response of perfusion pressure to KCl was shifted significantly towards lower perfusion pressures as compared with normotensive controls." | 1.28 | Vascular reactivity in isolated lungs of rats with spontaneous systemic hypertension. ( Hampl, V; Herget, J, 1991) |
| " The change in sensitivity was characterized by a leftward shift of the dose-response curve without a change in maximum response." | 1.28 | Specific supersensitivity of the mesenteric vascular bed of Dahl salt-sensitive rats. ( Fleming, WW; Kong, JQ; Kotchen, TA; Taylor, DA, 1991) |
| " H-7 produced a shift to the right of the dose-response curve for the PKC activator, 12-o-tetradecanoylphorbol-13-acetate (TPA) in the case of SHR aortas, while no such shift was noted in tissues from WKY." | 1.28 | Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats. ( Iwasaki, T; Miyata, S; Morita, S; Nagai, K; Shibata, R, 1990) |
| " Full dose-response curves to noradrenaline, vasopressin and potassium chloride were established." | 1.28 | Increased sensitivity to noradrenaline in glucocorticoid-treated rats: the effects of indomethacin and desipramine. ( Fraser, R; Kenyon, CJ; Russo, D, 1990) |
| "Rats treated with desoxycorticosterone acetate and sodium chloride (DOCA/NaCl) developed a time-dependent increase in blood pressure which was associated with a reduced in vitro beta- and an elevated alpha-adrenergic responsiveness." | 1.27 | Time course alterations in vascular adrenergic responsiveness in the DOCA/NaCl-treated rat. ( Field, FP; Iloeje, E; Katovich, MJ; Soltis, EE, 1984) |
| "Potassium chloride (48 mmol/day) was given to 36 male patients with high blood pressure; 5 did not comply with therapy." | 1.27 | The role of potassium in control of blood pressure. ( Morgan, T; Myers, J; Teow, BH, 1984) |
| "Pretreatment with methyclothiazide also attenuated the elevation in blood pressure but did not affect the responsiveness to hypothalamic stimulation; hence increased natriuresis or diuresis alone could not account for the effects induced by KCl." | 1.27 | KCl inhibits hypothalamic activity to attenuate hypertension in DOCA-salt rats. ( Ijichi, H; Iyoda, I; Okajima, H; Sasaki, S; Takahashi, H; Takeda, K; Yoneda, S; Yoshimura, M, 1984) |
| " Cumulative dose-response curves to NE or KC1 were similar for strips from controls and hypertensive animals in both forms of hypertension." | 1.27 | Contractile responses of vasa deferentia from rats with genetic and experimental hypertension. ( Daniel, EE; Kwan, CY; Sakai, Y, 1984) |
| "Patients with hypertension are frequently on a number of different anti-hypertensive agents, and if they have other chronic disorders they may take as many as 10 different drugs and up to 40 tablets per day." | 1.27 | Compliance and the elderly hypertensive. ( Morgan, TO; Murphy, J; Nowson, C; Snowden, R, 1986) |
| "The treatment with nifedipine induced a significant reduction in both systolic and diastolic blood pressures; the infusions of angiotensin II (0." | 1.27 | Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients. ( Leonetti, G; Terzoli, L; Zanchetti, A, 1987) |
| " Dose-response curves in low Ca2+ (0." | 1.27 | Extracellular calcium and altered vascular responsiveness in the deoxycorticosterone acetate-salt rat. ( Field, FP; Soltis, EE, 1986) |
| " Dose-response curves were obtained using a non-specific vasoconstrictor (KCl) and an alpha-adrenergic agonist, phenylephrine." | 1.27 | Attenuation of alpha-adrenergic responsiveness in hypoxic SHR. ( Henley, WN; Tucker, A, 1986) |
| "Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis." | 1.26 | Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980) |
| "Hypertension was not obviously associated with hyperfunction of the thyroid gland." | 1.26 | Role of the thyroid gland in the development and maintenance of spontaneous hypertension in rats. ( Berkowitz, BA; Rioux, F, 1977) |
| "Thus, hypertension is not the result of an absence of beta receptor or a hypersensitivity of the vascular smooth muscle." | 1.25 | Vascular smooth muscle reactivity in normotensive and hypertensive rats. ( Brodie, BB; Fleisch, JH; Maling, HM; Spector, S, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 205 (48.35) | 18.7374 |
| 1990's | 101 (23.82) | 18.2507 |
| 2000's | 70 (16.51) | 29.6817 |
| 2010's | 41 (9.67) | 24.3611 |
| 2020's | 7 (1.65) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 2 |
| Su, XL | 1 |
| Bai, TT | 1 |
| Qin, W | 1 |
| Li, AH | 1 |
| Liu, YX | 1 |
| Wang, M | 1 |
| Wang, JK | 1 |
| Xing, L | 1 |
| Li, HJ | 1 |
| He, CX | 1 |
| Zhou, X | 2 |
| Zhao, D | 2 |
| Li, PQ | 1 |
| Wu, SP | 1 |
| Liu, JL | 1 |
| Chen, YL | 1 |
| Cao, HL | 1 |
| Zidek, W | 1 |
| Jacobson, MF | 1 |
| Campbell, NRC | 2 |
| Greer, RC | 1 |
| Marklund, M | 3 |
| Anderson, CAM | 1 |
| Cobb, LK | 1 |
| Dalcin, AT | 1 |
| Henry, M | 1 |
| Appel, LJ | 2 |
| Huang, L | 2 |
| Tian, M | 2 |
| Yu, J | 1 |
| Li, Q | 1 |
| Liu, Y | 1 |
| Yin, X | 2 |
| Wu, JH | 1 |
| Wu, Y | 2 |
| Li, N | 1 |
| Elliott, P | 1 |
| Yan, LL | 2 |
| Labarthe, DR | 1 |
| Hao, Z | 1 |
| Shi, J | 1 |
| Feng, X | 1 |
| Zhang, J | 1 |
| Zhang, Y | 2 |
| Zhang, R | 1 |
| Zhou, B | 2 |
| Li, Z | 1 |
| Sun, J | 1 |
| Zhao, Y | 2 |
| Yu, Y | 1 |
| Neal, B | 2 |
| Singh, G | 1 |
| Greer, R | 1 |
| Cudhea, F | 1 |
| Matsushita, K | 1 |
| Micha, R | 1 |
| Brady, T | 1 |
| Cobb, L | 1 |
| Mozaffarian, D | 1 |
| Wu, JHY | 1 |
| Fujioka, Y | 1 |
| Otani, K | 1 |
| Okada, M | 1 |
| Yamawaki, H | 1 |
| Preston, RA | 1 |
| Afshartous, D | 1 |
| Caizapanta, EV | 1 |
| Materson, BJ | 1 |
| Rodco, R | 1 |
| Alonso, E | 1 |
| Alonso, AB | 1 |
| Chen, KC | 1 |
| Chu, P | 1 |
| Wang, LJ | 1 |
| Ma, KT | 1 |
| Shi, WY | 1 |
| Wang, YZ | 1 |
| Zhao, L | 1 |
| Chen, XY | 1 |
| Li, XZ | 1 |
| Jiang, XW | 1 |
| Zhang, ZS | 1 |
| Si, JQ | 1 |
| Nowacki, D | 1 |
| Martynowicz, H | 1 |
| Skoczyńska, A | 1 |
| Wojakowska, A | 1 |
| Turczyn, B | 1 |
| Bobak, Ł | 1 |
| Trziszka, T | 1 |
| Szuba, A | 1 |
| Kreutzträger, M | 1 |
| Kopp, MA | 1 |
| Liebscher, T | 1 |
| Shekhar, S | 1 |
| Dharmshaktu, P | 1 |
| Porras-González, C | 1 |
| Castellano, A | 1 |
| Ureña, J | 1 |
| Mandoe, MJ | 1 |
| Borg, R | 1 |
| Hansen, D | 1 |
| Farrand, C | 1 |
| MacGregor, G | 1 |
| Webster, J | 2 |
| Ng, HK | 1 |
| Poh, TF | 1 |
| Lam, SK | 1 |
| Hoe, SZ | 1 |
| Zhao, X | 1 |
| Li, X | 1 |
| Lam, CT | 1 |
| Li, S | 1 |
| He, F | 1 |
| Xie, W | 1 |
| Sang, B | 1 |
| Luobu, G | 1 |
| Ke, L | 1 |
| Ozdemir, A | 1 |
| Şahan, G | 1 |
| Demirtaş, A | 1 |
| Aypar, E | 1 |
| Gözübüyük, G | 1 |
| Turan, NN | 1 |
| Ark, M | 1 |
| Vogel, PA | 1 |
| Yang, X | 1 |
| Moss, NG | 2 |
| Arendshorst, WJ | 1 |
| Silva, TL | 1 |
| Mota, MM | 1 |
| Fontes, MT | 1 |
| Araújo, JE | 1 |
| Oliveira Carvalho, V | 1 |
| Bonjardim, LR | 1 |
| Santos, MR | 1 |
| Lopes, RA | 1 |
| Neves, KB | 1 |
| Tostes, RC | 1 |
| Montezano, AC | 1 |
| Touyz, RM | 1 |
| Qu, JT | 1 |
| Zhang, DX | 1 |
| Liu, F | 2 |
| Mao, HP | 1 |
| Ma, YK | 1 |
| Yang, Y | 1 |
| Li, CX | 1 |
| Qiu, LZ | 1 |
| Geng, X | 1 |
| Zhang, JM | 1 |
| Gao, XM | 1 |
| Chen, L | 1 |
| Wang, H | 3 |
| Madlala, HP | 1 |
| Metzinger, T | 1 |
| van Heerden, FR | 1 |
| Musabayane, CT | 1 |
| Mubagwa, K | 1 |
| Dessy, C | 1 |
| Nguyen, HT | 2 |
| Islam, MZ | 1 |
| Obi, T | 1 |
| Pothinuch, P | 1 |
| Zar, PP | 1 |
| Hou, de X | 1 |
| Van Nguyen, T | 1 |
| Nguyen, TM | 1 |
| Van Dao, C | 1 |
| Shiraishi, M | 1 |
| Miyamoto, A | 1 |
| Fu, LY | 1 |
| Wang, HL | 1 |
| Wu, XM | 1 |
| Wang, WL | 1 |
| Shi, JP | 1 |
| Vongpatanasin, W | 1 |
| Peri-Okonny, P | 1 |
| Velasco, A | 1 |
| Arbique, D | 1 |
| Wang, Z | 1 |
| Ravikumar, P | 1 |
| Adams-Huet, B | 1 |
| Moe, OW | 1 |
| Pak, CYC | 1 |
| Bal, MS | 1 |
| Paulis, L | 1 |
| Zicha, J | 1 |
| Kunes, J | 1 |
| Sullivan, JC | 1 |
| Pardieck, JL | 1 |
| Doran, D | 1 |
| She, JX | 1 |
| Pollock, JS | 1 |
| Ball, CJ | 1 |
| Wilson, DP | 1 |
| Turner, SP | 1 |
| Saint, DA | 1 |
| Beltrame, JF | 1 |
| Al-Solaiman, Y | 1 |
| Jesri, A | 1 |
| Morrow, JD | 1 |
| Egan, BM | 1 |
| Park, SH | 1 |
| Dutta, NK | 1 |
| Baek, MW | 1 |
| Kim, DJ | 1 |
| Na, YR | 1 |
| Seok, SH | 1 |
| Lee, BH | 1 |
| Cho, JE | 1 |
| Cho, GS | 1 |
| Park, JH | 1 |
| Liu, JX | 1 |
| Shi, R | 1 |
| Yang, N | 1 |
| Song, DL | 1 |
| Pang, W | 1 |
| Li, YM | 1 |
| Graham, DA | 1 |
| Rush, JW | 1 |
| Seifi, B | 1 |
| Kadkhodaee, M | 1 |
| Karimian, SM | 1 |
| Zahmatkesh, M | 1 |
| Shams, S | 1 |
| Bakhshi, E | 1 |
| Schmidlin, O | 4 |
| Tanaka, M | 4 |
| Sebastian, A | 2 |
| Morris, RC | 5 |
| Chen, YY | 1 |
| Ji, W | 1 |
| Du, JR | 1 |
| Yu, DK | 1 |
| He, Y | 1 |
| Yu, CX | 1 |
| Li, DS | 1 |
| Zhao, CY | 1 |
| Qiao, KY | 1 |
| He, FJ | 2 |
| Marciniak, M | 1 |
| Carney, C | 1 |
| Markandu, ND | 6 |
| Anand, V | 1 |
| Fraser, WD | 1 |
| Dalton, RN | 1 |
| Kaski, JC | 1 |
| MacGregor, GA | 7 |
| Deng, H | 1 |
| Hershenson, MB | 1 |
| Lei, J | 1 |
| Anyanwu, AC | 1 |
| Pinsky, DJ | 1 |
| Bentley, JK | 1 |
| Dorafshar, AH | 1 |
| Moodley, K | 1 |
| Khoe, M | 1 |
| Lyon, C | 1 |
| Bryer-Ash, M | 1 |
| Galdino, GS | 1 |
| Lopes, AM | 1 |
| Franca, VM | 1 |
| Duarte, ID | 1 |
| Perez, AC | 1 |
| Kapil, V | 1 |
| Milsom, AB | 1 |
| Okorie, M | 1 |
| Maleki-Toyserkani, S | 1 |
| Akram, F | 1 |
| Rehman, F | 1 |
| Arghandawi, S | 1 |
| Pearl, V | 1 |
| Benjamin, N | 1 |
| Loukogeorgakis, S | 1 |
| Macallister, R | 1 |
| Hobbs, AJ | 1 |
| Webb, AJ | 1 |
| Ahluwalia, A | 1 |
| Xavier, FE | 2 |
| Blanco-Rivero, J | 1 |
| Avendaño, MS | 1 |
| Sastre, E | 1 |
| Yela, R | 1 |
| Velázquez, K | 1 |
| Salaíces, M | 2 |
| Balfagón, G | 2 |
| He, X | 1 |
| Zhang, HL | 1 |
| Zhao, M | 1 |
| Yang, JL | 1 |
| Cheng, G | 1 |
| Sun, L | 1 |
| Li, DL | 1 |
| Jiang, HK | 1 |
| Zhao, Q | 1 |
| Yu, XJ | 1 |
| Zang, WJ | 1 |
| He, WQ | 1 |
| Qiao, YN | 1 |
| Zhang, CH | 1 |
| Peng, YJ | 1 |
| Chen, C | 2 |
| Wang, P | 1 |
| Gao, YQ | 1 |
| Chen, X | 1 |
| Tao, T | 1 |
| Su, XH | 1 |
| Li, CJ | 1 |
| Kamm, KE | 1 |
| Stull, JT | 1 |
| Zhu, MS | 1 |
| Gavish, B | 1 |
| Alter, A | 1 |
| Barkai, Y | 1 |
| Rachima-Maoz, C | 1 |
| Peleg, E | 1 |
| Rosenthal, T | 1 |
| El-Bassossy, HM | 2 |
| Fahmy, A | 2 |
| Badawy, D | 1 |
| Lloyd, EE | 1 |
| Crossland, RF | 1 |
| Phillips, SC | 1 |
| Marrelli, SP | 1 |
| Reddy, AK | 1 |
| Taffet, GE | 1 |
| Hartley, CJ | 1 |
| Bryan, RM | 1 |
| Sarkkinen, ES | 1 |
| Kastarinen, MJ | 1 |
| Niskanen, TH | 1 |
| Karjalainen, PH | 1 |
| Venäläinen, TM | 1 |
| Udani, JK | 1 |
| Niskanen, LK | 1 |
| Schillaci, G | 1 |
| Pucci, G | 1 |
| Chow, KM | 1 |
| Ma, RC | 1 |
| Szeto, CC | 1 |
| Li, PK | 1 |
| Mustafa, AK | 1 |
| Sikka, G | 1 |
| Gazi, SK | 1 |
| Steppan, J | 1 |
| Jung, SM | 1 |
| Bhunia, AK | 1 |
| Barodka, VM | 1 |
| Gazi, FK | 1 |
| Barrow, RK | 1 |
| Wang, R | 2 |
| Amzel, LM | 1 |
| Berkowitz, DE | 1 |
| Snyder, SH | 1 |
| Rocha, ML | 1 |
| Araujo, AV | 1 |
| Andrade, FA | 1 |
| Bendhack, LM | 1 |
| Abo-Warda, SM | 1 |
| Asmar, A | 1 |
| Mohandas, R | 1 |
| Wingo, CS | 1 |
| Zheng, S | 1 |
| Mu, J | 1 |
| Chu, C | 1 |
| Wang, L | 1 |
| Wang, Y | 1 |
| Xiao, H | 1 |
| Wang, D | 1 |
| Cao, Y | 1 |
| Ren, K | 1 |
| Liu, E | 1 |
| Yuan, Z | 1 |
| Morato, M | 1 |
| Sousa, T | 1 |
| Guimarães, S | 1 |
| Moura, D | 1 |
| Albino-Teixeira, A | 1 |
| Yamanaka, M | 1 |
| Hayashi, I | 1 |
| Fujita, T | 5 |
| Cha, SH | 1 |
| Endou, H | 1 |
| Higashihara, M | 1 |
| Majima, M | 1 |
| Wong, CM | 1 |
| O'Connor, DT | 1 |
| Martinez, JA | 1 |
| Kailasam, MT | 1 |
| Parmer, RJ | 1 |
| Büssemaker, E | 1 |
| Popp, R | 1 |
| Fisslthaler, B | 1 |
| Larson, CM | 1 |
| Fleming, I | 1 |
| Busse, R | 1 |
| Brandes, RP | 1 |
| MENEELY, GR | 1 |
| BALL, CO | 1 |
| GRIEBLE, HG | 2 |
| JOHNSTON, LC | 2 |
| FULLER, JB | 1 |
| DIEBOLD, A | 1 |
| CAPDEVILLE, R | 1 |
| DELAHAYE, JP | 1 |
| SIBONI, M | 1 |
| GONIN, A | 1 |
| COLLYNS, JA | 1 |
| MACQUAIDE, DH | 1 |
| BELLUSCHI, A | 1 |
| VACCHINI, V | 1 |
| FUKUCHI, S | 1 |
| HANATA, M | 1 |
| TAKAHASHI, H | 2 |
| DEMURA, H | 1 |
| GOTO, K | 1 |
| GRAFZUDOHNA, P | 1 |
| PFISTERER, A | 1 |
| Subramanian, R | 1 |
| MacLeod, KM | 1 |
| Galisteo, M | 1 |
| García-Saura, MF | 1 |
| Jiménez, R | 1 |
| Villar, IC | 1 |
| Wangensteen, R | 1 |
| Zarzuelo, A | 2 |
| Vargas, F | 2 |
| Duarte, J | 2 |
| Rossoni, LV | 1 |
| Alonso, MJ | 1 |
| Vassallo, DV | 1 |
| de Moura, RS | 1 |
| Miranda, DZ | 1 |
| Pinto, AC | 1 |
| Sicca, RF | 1 |
| Souza, MA | 1 |
| Rubenich, LM | 1 |
| Carvalho, LC | 1 |
| Rangel, BM | 1 |
| Tano, T | 1 |
| Madeira, SV | 1 |
| Resende, AC | 1 |
| Ghosh, M | 1 |
| Hanna, ST | 1 |
| McNeill, JR | 2 |
| Gendron, G | 1 |
| Gobeil, F | 1 |
| Morin, J | 1 |
| D'Orléans-Juste, P | 1 |
| Regoli, D | 1 |
| Coltart, R | 1 |
| Barron, J | 1 |
| Allahdadi, KJ | 1 |
| Walker, BR | 1 |
| Kanagy, NL | 2 |
| Girouard, H | 1 |
| de Champlain, J | 1 |
| Bollen, AW | 1 |
| Yi, SL | 2 |
| Tatchum-Talom, R | 1 |
| Eyster, KM | 1 |
| Martin, DS | 2 |
| Pérez-Guerrero, C | 1 |
| Márquez-Martín, A | 1 |
| Herrera, MD | 1 |
| Marhuenda, E | 1 |
| Alvarez de Sotomayor, M | 1 |
| Keys, JR | 1 |
| Zhou, RH | 1 |
| Harris, DM | 1 |
| Druckman, CA | 1 |
| Eckhart, AD | 1 |
| Allan, A | 1 |
| Fenning, A | 1 |
| Levick, S | 1 |
| Hoey, A | 1 |
| Brown, L | 2 |
| Galligan, JJ | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| China Salt Substitute Study in Tibet: Efficacy of Salt Substitute in Reducing Blood Pressure in Hypertensive Adults[NCT01429246] | 282 participants (Actual) | Interventional | 2009-02-28 | Completed | |||
| Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension[NCT01682837] | Phase 2 | 35 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)[NCT01942395] | 18 participants (Actual) | Interventional | 2012-09-18 | Terminated (stopped due to study diet is no longer available to match with the previous participants.) | |||
| Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension[NCT02653560] | Phase 4 | 30 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| Investigation of the Sex Differences in Oral Microbiota and Their Effect on Circulating Nitrite Levels[NCT01583803] | 24 participants (Anticipated) | Observational | 2012-06-30 | Active, not recruiting | |||
| The Acute Effect of Beetroot Juice on Circulating Nitrate and Nitrite Levels and Blood Pressure in Normotensives and Hypertensives[NCT01236872] | 15 participants (Actual) | Interventional | 2009-12-31 | Completed | |||
| Effect of the Interaction Between Environmental Factors and Genetic Predisposition on Long-term Blood Pressure in Chinese Population[NCT02734472] | 5,298 participants (Anticipated) | Observational | 2016-07-31 | Recruiting | |||
| Genetics Study of Salt-Sensitive Hypertension in a Chinese Population[NCT02915315] | 70 participants (Anticipated) | Observational | 2017-02-28 | Not yet recruiting | |||
| A Pilot Study of the Effect of Dietary Sodium Intake on Assessments of Vascular Endothelium[NCT01550315] | 27 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| [NCT00005150] | 0 participants | Observational | 1980-07-31 | Completed | |||
| [NCT00000528] | Phase 3 | 0 participants | Interventional | 1986-09-30 | Completed | ||
| Sodium-Potassium Blood Pressure Trial in Children[NCT00000521] | Phase 4 | 285 participants (Actual) | Interventional | 1985-08-31 | Completed | ||
| [NCT00000509] | Phase 3 | 0 participants | Interventional | 1983-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The average diastolic blood pressure over a 24 hour period. (NCT01682837)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 79 |
| Potassium Citrate Powder Phase | 78 |
| Potassium Chloride Powder Phase | 78 |
| Placebo Phase | 80 |
This is the average systolic blood pressure over a 24 hour period. (NCT01682837)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 127 |
| Potassium Citrate Powder Phase | 127 |
| Potassium Chloride Powder Phase | 126 |
| Placebo Phase | 129 |
(NCT01682837)
Timeframe: 4 weeks of treatment
| Intervention | mg/day (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 158 |
| Potassium Citrate Powder Phase | 148 |
| Potassium Chloride Powder Phase | 160 |
| Placebo Phase | 181 |
(NCT01682837)
Timeframe: 4 weeks
| Intervention | m/s (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 8.7 |
| Potassium Citrate Powder Phase | 8.8 |
| Potassium Chloride Powder Phase | 8.7 |
| Placebo Phase | 8.9 |
(NCT01682837)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 77 |
| Potassium Citrate Powder Phase | 76 |
| Potassium Chloride Powder Phase | 77 |
| Placebo Phase | 79 |
(NCT01682837)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 121 |
| Potassium Citrate Powder Phase | 125 |
| Potassium Chloride Powder Phase | 123 |
| Placebo Phase | 126 |
(NCT01682837)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 81 |
| Potassium Citrate Powder Phase | 81 |
| Potassium Chloride Powder Phase | 80 |
| Placebo Phase | 81 |
(NCT01682837)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 124 |
| Potassium Citrate Powder Phase | 125 |
| Potassium Chloride Powder Phase | 127 |
| Placebo Phase | 129 |
(NCT01682837)
Timeframe: 4 weeks
| Intervention | ng/ml (Mean) |
|---|---|
| Potassium Magnesium Citrate Powder Phase | 0.46 |
| Potassium Citrate Powder Phase | 0.46 |
| Potassium Chloride Powder Phase | 0.45 |
| Placebo Phase | 0.49 |
Systolic blood pressure was measured through an ambulatory blood pressure monitoring device worn by each participant for 24 hours after completing each treatment phase. This devise measures blood pressure intermittently throughout the day and night and provides the average of all readings. (NCT02653560)
Timeframe: 4 weeks
| Intervention | mmHg (Mean) |
|---|---|
| Potassium Magnesium Citrate (KMgCit) Arm | 127 |
| Potassium Citrate Arm | 127 |
| Potassium Chloride Arm | 126 |
| Placebo | 129 |
The primary analysis will involve a non-parametric, paired, Signed Rank test of flow mediated dilation (FMD) between all subjects (POTS & control subjects) on the high sodium diet vs low sodium diet (NCT01550315)
Timeframe: FMD was assessed on the morning of day 7, after 6 days of being on either a high salt diet or a low salt diet.
| Intervention | percentage of change (Mean) |
|---|---|
| High Sodium POTS | 12.75 |
| Low Sodium Diet POTS | 11.65 |
| High Sodium Controls | 11.43 |
| Low Sodium Controls | 12.75 |
11 reviews available for potassium chloride and Hypertension
| Article | Year |
|---|---|
[Can salt substitution or reduction replace pharmaceuticals for arterial hypertension?]
Topics: Antihypertensive Agents; Diuretics; Humans; Hyperkalemia; Hypertension; Pharmaceutical Preparations; | 2022 |
Potassium-Enriched Salt Substitutes as a Means to Lower Blood Pressure: Benefits and Risks.
Topics: Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Potassium Chloride; Risk Assessment; | 2020 |
The effect of adrenergic blockade on potassium concentrations in different conditions.
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Epinephrine; Humans; Hypertension; Pindolol; Pota | 1983 |
Diuretics, potassium depletion and the risk of arrhythmias.
Topics: Aerospace Medicine; Arrhythmias, Cardiac; Benzothiadiazines; Diuretics; Humans; Hypertension; Hypoka | 1984 |
Managing diuretic-induced hypokalemia in ambulatory hypertensive patients.
Topics: Aged; Ambulatory Care; Chlorthalidone; Diuretics; Food; Humans; Hydrochlorothiazide; Hypertension; H | 1982 |
Differing effects of supplemental KCl and KHCO3: pathophysiological and clinical implications.
Topics: Adult; Animals; Bicarbonates; Child; Child, Preschool; Dietary Supplements; Humans; Hypertension; Mi | 1999 |
[Therapeutic use of sodium chloride substitutes in circulatory insufficiency].
Topics: Animals; Diet, Sodium-Restricted; Diuretics; Heart Failure; Humans; Hypertension; Potassium Chloride | 1989 |
Essential hypertension: new insights and controversies in treatment with diuretics.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Dose-Response Relat | 1986 |
Combination antihypertensive therapy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamine; Antidepressive Agents; Antih | 1971 |
Significance of hypokalaemia due to diuretics.
Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Fu | 1973 |
[Current diuretic treatment. Physiopathologic basis].
Topics: Acute Disease; Alkalosis; Anuria; Calcium; Chlorine; Chronic Disease; Diabetes Insipidus; Diuretics; | 1970 |
55 trials available for potassium chloride and Hypertension
| Article | Year |
|---|---|
Interim effects of salt substitution on urinary electrolytes and blood pressure in the China Salt Substitute and Stroke Study (SSaSS).
Topics: Aged; Blood Pressure; China; Cooking; Diet, Sodium-Restricted; Female; Food Preservation; Humans; Hy | 2020 |
Using a low-sodium, high-potassium salt substitute to reduce blood pressure among Tibetans with high blood pressure: a patient-blinded randomized controlled trial.
Topics: Administration, Oral; Aged; Blood Pressure; Blood Pressure Determination; Ethnicity; Female; Humans; | 2014 |
Intake of low sodium salt substitute for 3years attenuates the increase in blood pressure in a rural population of North China - A randomized controlled trial.
Topics: Adult; Blood Pressure; Blood Pressure Determination; China; Double-Blind Method; Female; Humans; Hyp | 2016 |
Effects of Potassium Magnesium Citrate Supplementation on 24-Hour Ambulatory Blood Pressure and Oxidative Stress Marker in Prehypertensive and Hypertensive Subjects.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Citrate | 2016 |
Low-Sodium DASH reduces oxidative stress and improves vascular function in salt-sensitive humans.
Topics: Adult; Aldosterone; Aorta; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Elasticity; Elec | 2009 |
Compound ion salt, a novel low-sodium salt substitute: from animal study to community-based population trial.
Topics: Aged; Aged, 80 and over; Animals; Blood Pressure; Calcium Carbonate; Calcium Citrate; Electrolytes; | 2009 |
Effects of potassium chloride and potassium bicarbonate on endothelial function, cardiovascular risk factors, and bone turnover in mild hypertensives.
Topics: Adult; Albuminuria; Bicarbonates; Blood Pressure; Bone Remodeling; Brachial Artery; Calcium; Cross-O | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Effect of non-drug interventions on arterial properties determined from 24-h ambulatory blood pressure measurements.
Topics: Adult; Aged; Aged, 80 and over; Arteries; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Bre | 2011 |
Feasibility and antihypertensive effect of replacing regular salt with mineral salt -rich in magnesium and potassium- in subjects with mildly elevated blood pressure.
Topics: Adult; Aged; Blood Pressure; Creatinine; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; | 2011 |
Common variation in with no-lysine kinase 1 (WNK1) and blood pressure responses to dietary sodium or potassium interventions- family-based association study.
Topics: Adolescent; Adult; Blood Pressure; Family; Female; Humans; Hypertension; Intracellular Signaling Pep | 2013 |
Common variation in with no-lysine kinase 1 (WNK1) and blood pressure responses to dietary sodium or potassium interventions- family-based association study.
Topics: Adolescent; Adult; Blood Pressure; Family; Female; Humans; Hypertension; Intracellular Signaling Pep | 2013 |
Common variation in with no-lysine kinase 1 (WNK1) and blood pressure responses to dietary sodium or potassium interventions- family-based association study.
Topics: Adolescent; Adult; Blood Pressure; Family; Female; Humans; Hypertension; Intracellular Signaling Pep | 2013 |
Common variation in with no-lysine kinase 1 (WNK1) and blood pressure responses to dietary sodium or potassium interventions- family-based association study.
Topics: Adolescent; Adult; Blood Pressure; Family; Female; Humans; Hypertension; Intracellular Signaling Pep | 2013 |
Effect of short-term supplementation of potassium chloride and potassium citrate on blood pressure in hypertensives.
Topics: Adult; Blood Pressure; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Hypertensio | 2005 |
Efficacy and safety of 24 weeks of therapy with bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride compared with enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension : a multicentre, randomis
Topics: Adult; Aged; Amlodipine; Bendroflumethiazide; Enalapril; Female; Humans; Hypertension; Male; Middle | 2006 |
Salt substitution: a low-cost strategy for blood pressure control among rural Chinese. A randomized, controlled trial.
Topics: Aged; Blood Pressure; China; Double-Blind Method; Female; Humans; Hypertension; Magnesium Sulfate; M | 2007 |
Salt substitution: a low-cost strategy for blood pressure control among rural Chinese. A randomized, controlled trial.
Topics: Aged; Blood Pressure; China; Double-Blind Method; Female; Humans; Hypertension; Magnesium Sulfate; M | 2007 |
Salt substitution: a low-cost strategy for blood pressure control among rural Chinese. A randomized, controlled trial.
Topics: Aged; Blood Pressure; China; Double-Blind Method; Female; Humans; Hypertension; Magnesium Sulfate; M | 2007 |
Salt substitution: a low-cost strategy for blood pressure control among rural Chinese. A randomized, controlled trial.
Topics: Aged; Blood Pressure; China; Double-Blind Method; Female; Humans; Hypertension; Magnesium Sulfate; M | 2007 |
Acceptability in food of NaCl/KCl mixture.
Topics: Diet, Sodium-Restricted; Food Preferences; Humans; Hypertension; Potassium Chloride; Sodium Chloride | 1983 |
Does increasing potassium intake lower blood pressure in essential hypertension?
Topics: Adult; Aged; Blood Pressure; Diet; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Potas | 1984 |
Comparative clinical trial of bemetizide/triamterene and cyclopenthiazide/potassium chloride combinations in patients with mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Benzothiadiazines; Blood Pressure; Body Weight; Clinical Trials as Topic; C | 1983 |
Low-sodium, high-potassium diet: feasibility and acceptability in a normotensive population.
Topics: Adult; Aged; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Female; Humans; Hypertension; Mal | 1984 |
Oxprenolol slow-release with cyclopenthiazide KCl in the treatment of essential hypertension. A multicentre general practice study.
Topics: Adult; Aged; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Cyclopenthiazide; Delayed-A | 1981 |
Combinations of potassium, calcium, and magnesium supplements in hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium; Calcium Carbonate; Confidence Intervals; Drug Therapy, Combina | 1995 |
[Potassium citrate versus potassium chloride in essential hypertension. Effects on hemodynamic, hormonal and metabolic parameters].
Topics: Adult; Aged; Aldosterone; Blood Glucose; Blood Pressure; Citrates; Citric Acid; Cross-Over Studies; | 1995 |
The effect of potassium supplementation in persons with a high-normal blood pressure. Results from phase I of the Trials of Hypertension Prevention (TOHP). Trials of Hypertension Prevention (TOHP) Collaborative Research Group.
Topics: Administration, Oral; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; | 1995 |
[2 antihypertensive therapeutic regimes compared in a controlled clinical trial in general practice. Cyclopenthiazide + KC1/methyldopa versus oxprenolol/hydralazine].
Topics: Adult; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Drug Evaluation; Drug Therapy, Combina | 1977 |
[Clinical studies of a sustained-release potassium salt preparation].
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Hypertension; Ma | 1977 |
Oxprenolol slow-release with cyclopenthiazide-KCl compared with methyldopa in the treatment of essential hypertension. A multicentre general practice trial.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Double-Blind Met | 1978 |
Maintenance of potassium balance during diuretic therapy.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Therapy, | 1979 |
Plasma potassium in hypertensive Africans on frusemide.
Topics: Adult; Aged; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Hypokalemia; Male; | 1978 |
Mild hypertension: a clinical trial conducted in hospital general practice.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Famil | 1976 |
Potassium chloride lowers blood pressure and causes natriuresis in older patients with hypertension.
Topics: Aged; Blood Pressure; Double-Blind Method; Humans; Hypertension; Middle Aged; Natriuresis; Potassium | 1992 |
The Sodium-Potassium Blood Pressure Trial in Children. Design, recruitment, and randomization: the children and adolescent blood pressure program.
Topics: Adolescent; Child; Diet, Sodium-Restricted; Double-Blind Method; Eligibility Determination; Female; | 1991 |
Adequacy of twice daily dosing with potassium chloride and spironolactone in thiazide treated hypertensive patients.
Topics: Adult; Aged; Bendroflumethiazide; Drug Administration Schedule; Drug Therapy, Combination; Female; H | 1991 |
Efficacy of potassium and magnesium in essential hypertension: a double-blind, placebo controlled, crossover study.
Topics: Adult; Cholesterol; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Magnesium | 1990 |
The influence of oral potassium chloride on blood pressure in hypertensive men on a low-sodium diet.
Topics: Administration, Oral; Blood Pressure; Diet, Sodium-Restricted; Double-Blind Method; Drug Evaluation; | 1990 |
[Evaluation of the need for potassium supplementation in patients subjected to furosemide therapy].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Furosemide; Heart Failure; Humans; Hypertension; Male | 1988 |
Haemodynamic and metabolic effects of prophylactic nitroglycerin infusion in the immediate period following coronary artery bypass grafting.
Topics: Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Artery Bypass; Female; Hemodynamics | 1988 |
Australian National Health and Medical Research Council dietary salt study in mild hypertension.
Topics: Blood Pressure; Delayed-Action Preparations; Diet; Diet, Sodium-Restricted; Female; Humans; Hyperten | 1986 |
Potassium supplementation in blacks with mild to moderate essential hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Middle Aged; Potassiu | 1986 |
Hypokalemia in thiazide-treated systemic hypertension.
Topics: Aldosterone; Amiloride; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothia | 1986 |
[Beta-blockers or thiazides for middle-aged and elderly patients with hypertension? A multicenter study in general practice].
Topics: Aged; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Humans; Hypertension; Middle Aged; Po | 1986 |
Therapeutic assessment of Slow-K and K-tab potassium chloride formulations in hypertensive patients treated with thiazide diuretics.
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Hydrochlorothiaz | 1987 |
Double-blind, placebo-controlled trial of potassium chloride in the treatment of mild hypertension.
Topics: Adult; Double-Blind Method; Heart Rate; Humans; Hypertension; Middle Aged; Placebos; Potassium Chlor | 1987 |
The effects of bendroflumethiazide/potassium chloride versus hydrochlorothiazide/amiloride on blood pressure and serum electrolytes in patients with mild to moderate hypertension seen in general practice.
Topics: Adult; Aged; Amiloride; Bendroflumethiazide; Blood Pressure; Drug Therapy, Combination; Electrolytes | 1986 |
Potassium supplementation in hypertensive patients with diuretic-induced hypokalemia.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; | 1985 |
Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Condiments; Female; Heart Rate; Humans; Hyperten | 1985 |
Potassium supplementation ameliorates hypertension in patients with diuretic-induced hypokalemia.
Topics: Clinical Trials as Topic; Diuretics; Double-Blind Method; Humans; Hypertension; Hypokalemia; Potassi | 1985 |
Atenolol versus bendroflumethiazide in middle-aged and elderly hypertensives.
Topics: Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combina | 1985 |
Effectiveness of potassium chloride or triamterene in thiazide hypokalemia.
Topics: Adult; Aged; Benzothiadiazines; Circadian Rhythm; Clinical Trials as Topic; Diuretics; Humans; Hyper | 1985 |
Potassium supplementation fails to lower blood pressure in hypertensive patients receiving a potassium losing diuretic.
Topics: Benzothiadiazines; Clinical Trials as Topic; Creatinine; Diuretics; Female; Humans; Hypertension; Ma | 1985 |
Hydrochlorothiazide and potassium chloride in comparison with hydrochlorothiazide and amiloride in the treatment of mild hypertension.
Topics: Adult; Aged; Amiloride; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Met | 1985 |
Potassium supplementation in essential hypertension--a double blind placebo controlled study.
Topics: Bicarbonates; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; Hypertension | 1985 |
Moderate potassium chloride supplementation in essential hypertension: is it additive to moderate sodium restriction?
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Combined Modality Therapy; Delayed-Action Pre | 1985 |
The efficacy of quantitative and qualitative chloride titrators in the estimation of human salt intake.
Topics: Adult; Child; Chlorides; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Humans; Hyperten | 1985 |
Comparison between alprenolol and chlorthalidone as antihypertensive agents.
Topics: Adult; Alprenolol; Amino Alcohols; Blood Pressure; Body Weight; Chlorthalidone; Clinical Trials as T | 1972 |
Dosage of potassium chloride elixir to correct thiazide-induced hypokalemia.
Topics: Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Plac | 1974 |
[On the treatment of hypertension].
Topics: Clinical Trials as Topic; Humans; Hydroflumethiazide; Hypertension; Phytotherapy; Plants, Medicinal; | 1965 |
358 other studies available for potassium chloride and Hypertension
| Article | Year |
|---|---|
New paeonol derivative C302 reduces hypertension in spontaneously hypertensive rats through endothelium-dependent and endothelium-independent vasodilation.
Topics: Acetophenones; Animals; Antihypertensive Agents; Endothelium, Vascular; Hypertension; Potassium Chlo | 2022 |
Potassium labeling of foods: Potential benefit for blood pressure.
Topics: Blood Pressure; Cardiovascular Diseases; Feeding Behavior; Food Labeling; Humans; Hypertension; Pota | 2019 |
Estimated population wide benefits and risks in China of lowering sodium through potassium enriched salt substitution: modelling study.
Topics: Adult; Aged; Blood Pressure; Cardiovascular Diseases; China; Diet, Sodium-Restricted; Female; Humans | 2020 |
Plasma small extracellular vesicles in hypertensive rats impair reactivity of isolated blood vessels.
Topics: Animals; Extracellular Vesicles; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Norepi | 2020 |
Thiazide-Sensitive NCC (Sodium-Chloride Cotransporter) in Human Metabolic Syndrome: Sodium Sensitivity and Potassium-Induced Natriuresis.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Na | 2021 |
The Case | Hypomagnesemia with knee pain.
Topics: Aged; Arthrocentesis; Chondrocalcinosis; Humans; Hydrochlorothiazide; Hypertension; Knee Joint; Magn | 2017 |
Enhanced gap junctional channel activity between vascular smooth muscle cells in cerebral artery of spontaneously hypertensive rats.
Topics: Animals; Boron Compounds; Cerebral Arteries; Connexin 43; Connexins; Electric Capacitance; Electroph | 2017 |
Lecithin derived from ω-3 PUFA fortified eggs decreases blood pressure in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Egg Yolk; Eggs; Fatty Acids, Omega-3; Food, Fortified; Heart Rate; Hyperten | 2017 |
Acute transient spinal paralysis and cardiac symptoms following an accidental epidural potassium infusion - a case report.
Topics: Aged; Analgesia, Epidural; Female; Humans; Hypertension; Injections, Epidural; Medication Errors; Pa | 2017 |
On the Palms of His Hands: ACTH-Induced Hyperpigmentation.
Topics: ACTH Syndrome, Ectopic; Adrenalectomy; Angiotensin Receptor Antagonists; Antihypertensive Agents; Ha | 2018 |
Contribution of L-type Ca
Topics: Animals; Calcium; Calcium Channels, L-Type; Hypertension; Male; Potassium Chloride; Rats; Rats, Inbr | 2018 |
Potassium chloride mixture may maintain hypokalaemia and hypertension.
Topics: Diagnosis, Differential; Female; Glycyrrhiza; Glycyrrhizic Acid; Humans; Hyperaldosteronism; Hyperte | 2018 |
Potential use of salt substitutes to reduce blood pressure.
Topics: Blood Pressure; Cardiovascular Diseases; Delivery of Health Care; Diet, Sodium-Restricted; Humans; H | 2019 |
Potassium channel openers and prostacyclin play a crucial role in mediating the vasorelaxant activity of Gynura procumbens.
Topics: Animals; Aorta, Thoracic; Asteraceae; Blood Pressure; Calcium; Calcium Channel Blockers; Epoprosteno | 2013 |
Chronic ouabain treatment induces Rho kinase activation.
Topics: Amides; Animals; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; Myosin-Light-Chain P | 2015 |
Superoxide enhances Ca2+ entry through L-type channels in the renal afferent arteriole.
Topics: Animals; Arterioles; Calcium; Calcium Channels, L-Type; Calcium Signaling; Hypertension; Kidney; Mal | 2015 |
Effects of one resistance exercise session on vascular smooth muscle of hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Enzyme Inhibitors; Exercise Tolerance; Hypertension; Mesenteri | 2015 |
Downregulation of Nuclear Factor Erythroid 2-Related Factor and Associated Antioxidant Genes Contributes to Redox-Sensitive Vascular Dysfunction in Hypertension.
Topics: Acetylcholine; Animals; Catalase; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Hypertens | 2015 |
Vasodilatory Effect of Wogonin on the Rat Aorta and Its Mechanism Study.
Topics: Animals; Aorta; Calcium; Drugs, Chinese Herbal; Endothelium, Vascular; Eucommiaceae; Flavanones; Hyp | 2015 |
Vascular Endothelium-Dependent and Independent Actions of Oleanolic Acid and Its Synthetic Oleanane Derivatives as Possible Mechanisms for Hypotensive Effects.
Topics: Animals; Antihypertensive Agents; Endothelium, Vascular; Hypertension; Hypotension; Indomethacin; Ma | 2016 |
Pharmacological characteristics of Artemisia vulgaris L. in isolated porcine basilar artery.
Topics: Animals; Artemisia; Basilar Artery; Female; Hypertension; In Vitro Techniques; Male; Medicine, Tradi | 2016 |
Effect of protein kinase C and protein kinase A inhibitors on contraction of isolated femoral arteries of SHR and Wistar rats.
Topics: Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Femoral Artery; Hype | 2009 |
Greater fractalkine expression in mesenteric arteries of female spontaneously hypertensive rats compared with males.
Topics: Acetylcholine; Animals; Chemokine CCL2; Chemokine CX3CL1; Disease Models, Animal; Female; Hypertensi | 2009 |
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydr | 2009 |
NaCl plus chitosan as a dietary salt to prevent the development of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Chitosan; | 2009 |
Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats.
Topics: Acetylcholine; Age Factors; Aging; Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Hetero | 2009 |
Reduction of kidney damage by supplementation of vitamins C and E in rats with deoxycorticosterone-salt-induced hypertension.
Topics: Animals; Antioxidants; Ascorbic Acid; Calcium Chloride; Desoxycorticosterone; Dietary Supplements; D | 2009 |
Selective chloride loading is pressor in the stroke-prone spontaneously hypertensive rat despite hydrochlorothiazide-induced natriuresis.
Topics: Animal Feed; Animals; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chlorides; Diuretics; D | 2010 |
Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in rats.
Topics: Alginates; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Disease Models, A | 2010 |
Pulmonary artery smooth muscle hypertrophy: roles of glycogen synthase kinase-3beta and p70 ribosomal S6 kinase.
Topics: Actins; Bone Morphogenetic Protein 4; Endothelin-1; Epidermal Growth Factor; Glycogen Synthase Kinas | 2010 |
Pioglitazone improves superoxide dismutase mediated vascular reactivity in the obese Zucker rat.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Glucose Tolerance Test; Hypertension; Hypoglycemic Ag | 2010 |
Evaluation of exercise and potassium chloride supplementation on blood pressure and nociceptive threshold in hypertensive rats.
Topics: Animals; Blood Pressure; Dietary Supplements; Disease Models, Animal; Exercise Therapy; Hypertension | 2010 |
Aldosterone alters the participation of endothelial factors in noradrenaline vasoconstriction differently in resistance arteries from normotensive and hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Collagen Type I; Endothelium, Vascular; Gene Expression Regula | 2011 |
Amlodipine ameliorates endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats.
Topics: Acetylcholine; Amlodipine; Animals; Antihypertensive Agents; Ascorbic Acid; Blood Pressure; Endothel | 2011 |
Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, D | 2011 |
Cinnamaldehyde protects from the hypertension associated with diabetes.
Topics: Acetylcholinesterase; Acrolein; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cal | 2011 |
Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 2011 |
The relationship between systolic and diastolic blood pressure: a clinically meaningful slope?
Topics: Arteries; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Breathing Exercises; Female; Humans | 2011 |
Polycystic kidney disease presenting with hypertension and hypokalemia.
Topics: Amides; Female; Fumarates; Humans; Hypertension; Hypokalemia; Middle Aged; Polycystic Kidney, Autoso | 2012 |
Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.
Topics: Acetylcholine; Animals; Aorta; Cells, Cultured; Charybdotoxin; Cystathionine gamma-Lyase; Endotheliu | 2011 |
The effects of gap junction modulators on the rhythmic contractions in aortas isolated from rats subjected with sinoaortic denervation.
Topics: Animals; Aorta; Blood Pressure; Cell Communication; Denervation; Dose-Response Relationship, Drug; E | 2011 |
Rosiglitazone, a peroxisome proliferator-activated receptor γ stimulant, abrogates diabetes-evoked hypertension by rectifying abnormalities in vascular reactivity.
Topics: Animals; Blood Glucose; Blood Pressure; Blood Vessels; Calcium; Cholesterol; Diabetes Mellitus, Expe | 2012 |
A physiologic-based approach to the treatment of a patient with hypokalemia.
Topics: Adult; Amiloride; Female; Follow-Up Studies; Humans; Hypertension; Hypokalemia; Liddle Syndrome; Pot | 2012 |
The role of angiotensin II in hypertension due to adenosine receptors blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; In Vitro Te | 2002 |
Potassium-induced increase in renal kallikrein secretion is attenuated in dissected renal connecting tubules of young spontaneously hypertensive rats.
Topics: Adamantane; Animals; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Kallikrein | 2002 |
Diminished renal kallikrein responses to mineralocorticoid stimulation in African Americans: determinants of an intermediate phenotype for hypertension.
Topics: Adult; Analysis of Variance; Black or African American; Fludrocortisone; Humans; Hypertension; Kalli | 2003 |
Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery.
Topics: Acetylcholine; Age Factors; Animals; Biological Factors; Cytochrome P-450 Enzyme Inhibitors; Enzyme | 2003 |
Experimental epidemiology of chronic sodium chloride toxicity and the protective effect of potassium chloride.
Topics: Chlorides; Hypertension; Potassium; Potassium Chloride; Sodium Chloride | 1958 |
Treatment of arterial hypertensive disease with diuretics. II. Effects on electrolytes and uric acid of bendroflumethiazide, potassium chloride, and spironolactone.
Topics: Bendroflumethiazide; Diuretics; Electrolytes; Humans; Hypertension; Potassium Chloride; Spironolacto | 1962 |
Treatment of arterial hypertensive disease with diuretics. I. Effects on blood pressure of bendroflumethiazide, potassium chloride, and spironolactone.
Topics: Bendroflumethiazide; Blood Pressure; Blood Pressure Determination; Diuretics; Humans; Hypertension; | 1962 |
[Arterial hypertension. Clinical experimentation with a new hypotensive comination: 10-methoxydeserpidine-benzthiazide-potassium chloride].
Topics: Alkaloids; Benzothiadiazines; Chlorides; Humans; Hypertension; Hypotension; Potassium; Potassium Chl | 1962 |
[THE COMBINATION OF CHLOROTHIAZIDE-RESERPINE-POTASSIUM CHLORIDE IN THE TREATMENT OF HYPERTENSIVE DISEASE].
Topics: Chlorides; Chlorothiazide; Drug Therapy; Hypertension; Potassium; Potassium Chloride; Reserpine | 1965 |
HYPOKALEMIC ALKALOSIS WITH ADRENAL TUMOR: A CASE REPORT. CONN'S SYNDROME OR DRUG-INDUCED HYPOKALEMIC ALKALOSIS.
Topics: Adenoma; Adrenal Gland Neoplasms; Alkalosis; Drug Therapy; Humans; Hydrochlorothiazide; Hyperaldoste | 1965 |
[CLINICAL EVALUATION OF A PHARMACOLOGIC ASSOCIATION WITH HYPOTENSIVE ACTION].
Topics: Antihypertensive Agents; Biomedical Research; Carbamates; Drug Therapy; Electric Impedance; Humans; | 1964 |
THE RELATIONSHIP BETWEEN VASCULAR REACTIVITY AND EXTRACELLULAR POTASSIUM.
Topics: Angiotensins; Blood Chemical Analysis; Blood Pressure; Blood Vessels; Body Weight; Chlorothiazide; C | 1965 |
[HIGH BLOOD PRESSURE THERAPY WITHOUT RESERPINE? A CONTRIBUTION TO THE THERAPY OF HYPERTENSION].
Topics: Alkaloids; Drug Therapy; Humans; Hydrochlorothiazide; Hypertension; Potassium Chloride; Rauwolfia; R | 1965 |
Age-dependent changes in blood pressure and arterial reactivity in obese Zucker rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Blood Pressure; Endothelin-1; Endothelium, Vascular; | 2003 |
Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Desoxycorticosterone; Disease Models, Anima | 2004 |
Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Cardiotonic Agents; Cyclooxygenase Inhibitors; | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Br | 2004 |
Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Canada; Cromakalim; Desoxycorticos | 2004 |
Contractile responses of aortae from WKY and SHR to vasoconstrictors.
Topics: Age Factors; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, D | 2004 |
Augmented endothelin vasoconstriction in intermittent hypoxia-induced hypertension.
Topics: Animals; Blood Pressure; Calcium; Endothelin-1; Hypertension; Hypoxia; In Vitro Techniques; Male; Me | 2005 |
Acute and chronic effects of free radicals on alpha1-adrenergic-induced vasoconstriction in mesenteric beds of spontaneously hypertensive rats.
Topics: Acute Disease; Animals; Antioxidants; Blood Pressure; Body Weight; Chronic Disease; Free Radicals; G | 2005 |
Chloride-dominant salt sensitivity in the stroke-prone spontaneously hypertensive rat.
Topics: Animals; Bicarbonates; Blood Pressure; Body Weight; Chlorides; Creatinine; Drug Combinations; Electr | 2005 |
Sexual dimorphism in angiotensin II-induced hypertension and vascular alterations.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Drinking; Eating; Female | 2005 |
Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin.
Topics: Amides; Animals; Aorta, Thoracic; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; End | 2005 |
Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cyclic AMP; Female; G-Protein-Coupled Receptor Kinas | 2005 |
Reversal of cardiac dysfunction by selective ET-A receptor antagonism.
Topics: Acetylcholine; Action Potentials; Animals; Aorta, Thoracic; Atrasentan; Body Weight; Collagen; Desox | 2005 |
Increased substance P content in nerve fibers associated with mesenteric veins from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Topics: Animals; Body Weight; Calcitonin Gene-Related Peptide; Desoxycorticosterone; Dose-Response Relations | 2006 |
Insulin improves the endothelium-independent relaxation and the contractile response in aorta from hypertensive diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypertension; In V | 2005 |
Effect of age on insulin-induced endothelin release and vasoreactivity in hypertriglyceridemic and hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Aorta; Blood Glucose; Blood Pressure; Endothelin Receptor A | 2006 |
Vasodilation mediated by inward rectifier K+ channels in cerebral microvessels of hypertensive and normotensive rats.
Topics: Animals; Arterioles; Barium Compounds; Blood Pressure; Brain; Cerebrovascular Circulation; Chlorides | 2006 |
Effect of pressure overload and its recovery on the rat carotid artery: change of vascular reactivity and remodeling process.
Topics: Acetylcholine; Animals; Apoptosis; Blood Pressure; Blotting, Western; Carotid Artery, Common; Diseas | 2006 |
Protective effect of potassium against the hypertensive cardiac dysfunction: association with reactive oxygen species reduction.
Topics: Animals; Blood Pressure; Body Weight; Dietary Supplements; Disease Models, Animal; Echocardiography; | 2006 |
Rho kinase contributes to androgen amplification of renal vasoconstrictor responses in the spontaneously hypertensive rat.
Topics: Androgens; Animals; Hypertension; Kidney; Male; Potassium Chloride; Rats; Rats, Inbred SHR; rho GTP- | 2006 |
Effects of daidzein sulfates on blood pressure and artery of rats.
Topics: Animals; Blood Pressure; Calcium; Calcium Chloride; Hypertension; In Vitro Techniques; Isoflavones; | 2006 |
Increased wall tension in response to vasoconstrictors in isolated mesenteric arterial rings from patients with high blood pressure.
Topics: Adult; Aged; Aged, 80 and over; Diclofenac; Female; Humans; Hypertension; In Vitro Techniques; Male; | 2006 |
Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, E | 2007 |
Internal mammary artery grafts reactivity in hypertensive patients: role of stretching in extraendothelial nitric oxide.
Topics: Aged; Angiotensin II; Biomechanical Phenomena; Endothelium, Vascular; Enzyme Inhibitors; Female; Hum | 2007 |
Effects of fully and partial substitution of NaCl by KCl on physico-chemical and sensory properties of white pickled cheese.
Topics: Analysis of Variance; Cheese; Food Handling; Hydrogen-Ion Concentration; Hypertension; Potassium Chl | 2008 |
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Blotti | 2008 |
Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.
Topics: Animals; Arterioles; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Anima | 2008 |
What effect does potassium have on blood pressure?
Topics: Animals; Blood Pressure; Humans; Hypertension; Potassium; Potassium Chloride | 2008 |
Circumferential small bowel ulcers: a report of nine cases.
Topics: Adult; Edema; Female; Humans; Hypertension; Ileum; Jejunum; Male; Middle Aged; Potassium Chloride; P | 1967 |
[Contribution to anti-hypertensive therapy with a drug combination].
Topics: Aged; Carbamates; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Middle Aged; | 1967 |
Time course alterations in vascular adrenergic responsiveness in the DOCA/NaCl-treated rat.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Muscle, Smooth, Vascular; Potassi | 1984 |
Potassium: the kitchen revisited.
Topics: Adult; Cooking; Humans; Hypertension; Obesity; Potassium Chloride; Vegetables | 1983 |
Potassium supplements and hypertension.
Topics: Adult; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Potassium Chloride | 1984 |
Economics of antihypertensive therapy.
Topics: Adrenergic beta-Agonists; Antihypertensive Agents; Benzothiadiazines; Costs and Cost Analysis; Diure | 1984 |
Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias.
Topics: Adult; Aged; Ambulatory Care; Antihypertensive Agents; Arrhythmias, Cardiac; Cardiac Complexes, Prem | 1983 |
Haemodynamic effects of increasing extracellular potassium concentration in ACTH-induced hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Animals; Cardiac Output; Hemodynamics; Hypertension; Potassium; Potassi | 1980 |
Plasma aldosterone and corticosterone responses to adrenocorticotropin, angiotensin, potassium, and stress in spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Hypertension; Mal | 1981 |
Characterization of the vasodilator action of antihypertensive drug budralazine.
Topics: Anesthesia; Animals; Antihypertensive Agents; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; Dogs; Ear, Ex | 1983 |
[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension].
Topics: Bicarbonates; Coronary Disease; Humans; Hypertension; Injections, Intravenous; Potassium; Potassium | 1984 |
Natriuretic and antihypertensive effects of potassium in DOCA-salt hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Depression, Chemical; Desoxycorticosterone; Dose-Response Rela | 1983 |
Coronary artery reactivity in deoxycorticosterone acetate hypertensive rats.
Topics: Acetylcholine; Adenosine; Animals; Arteries; Coronary Vessels; Desoxycorticosterone; Epoprostenol; H | 1984 |
Does potassium lower blood pressure by increasing sodium excretion? A metabolic study in patients with mild to moderate essential hypertension.
Topics: Aldosterone; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Potass | 1983 |
The role of potassium in control of blood pressure.
Topics: Aged; Blood Pressure; Diet, Sodium-Restricted; Electrolytes; Humans; Hypertension; Male; Middle Aged | 1984 |
KCl inhibits hypothalamic activity to attenuate hypertension in DOCA-salt rats.
Topics: Anesthesia; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Electric Stimulation; Heart | 1984 |
Fall in blood pressure in response to volume expansion in pregnancy-associated hypertension (pre-eclampsia): why does it occur?
Topics: Adult; Blood Pressure; Blood Proteins; Female; Gluconates; Humans; Hypertension; Isotonic Solutions; | 1984 |
Contractile responses of vasa deferentia from rats with genetic and experimental hypertension.
Topics: Animals; Blood Pressure; Calcium; Desoxycorticosterone; Dose-Response Relationship, Drug; Electric S | 1984 |
In vivo release of endogenous catecholamines, histamine and GABA in the hypothalamus of Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Catecholamines; Dopamine; Epinephrine; gamma-Aminobutyric Acid; Histamine; Hypertension; Hy | 1983 |
Indoramin in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Cyclopenthiazide; Drug Combinations; Drug Therapy, | 1983 |
[Antihypertensive action of K in rats with DOCA-salt-induced hypertension].
Topics: Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; Norepin | 1983 |
Potassium protects against renal tubule lesions in NaCl-fed hypertensive Dahl S rats.
Topics: Animals; Citrates; Citric Acid; Hypertension; Kidney; Kidney Tubules; Nephrosclerosis; Potassium; Po | 1983 |
The antihypertensive effect of dietary potassium chloride loading in rats with adrenal regeneration hypertension.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Pressure; Blood Proteins; Corticosterone; Electrolytes; | 1984 |
Baroreflex sensitivity and susceptibility to systolic hypertension induced by DOCA-salt in the Sabra rat.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Heart Rate; Hypertension; Male; Potassium Chloride; P | 1984 |
Effect of potassium chloride supplements on upper gastrointestinal mucosa.
Topics: Delayed-Action Preparations; Endoscopy; Gastric Mucosa; Glycopyrrolate; Humans; Hypertension; Intest | 1984 |
Ontogenesis of hypertension and responsiveness to antihypertensive agents in spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Guanethidine; Heart Rate; Hypertensi | 1980 |
[Low-salt diet for patients with hypertension. Salt substitutes: an alternative?].
Topics: Diet, Sodium-Restricted; Humans; Hypertension; Potassium Chloride | 1981 |
Long-term control of hypertension with Diumide-K.
Topics: Adult; Drug Combinations; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Potassium Chl | 1983 |
Reactivity of isolated digital arteries in hypertension.
Topics: Angiotensin II; Barium; Barium Compounds; Chlorides; Cyproheptadine; Female; Hand; Humans; Hypertens | 1981 |
Prostacyclin-induced contraction of isolated aortic strips from normal and spontaneously hypertensive rats (SHR).
Topics: Animals; Aorta, Thoracic; Calcium; Epoprostenol; Female; Hypertension; In Vitro Techniques; Male; Me | 1980 |
Inhibition by methoxyverapamil of the responses of smooth muscle from spontaneously hypertensive and normotensive rats.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Drug Interactions; Gallopamil; Hypertens | 1982 |
Inhibitory effect of potassium on blood pressure in DOCA salt hypertension in rats.
Topics: Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Diuresis; Drinking; Electrolytes; Hypert | 1981 |
[A possibility for cooking salt restriction. Properties and composition of a new strictly sodium poor diet salt].
Topics: Diet, Sodium-Restricted; Humans; Hypertension; Potassium Chloride | 1981 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di | 1980 |
The responses of carotid vascular strips from spontaneously hypertensive and normotensive rats.
Topics: Animals; Blood Pressure; Calcium; Carotid Arteries; Hypertension; In Vitro Techniques; Muscle Contra | 1980 |
The reactivity of iliac vascular strips from spontaneously hypertensive and normotensive rats.
Topics: Aging; Animals; Blood Pressure; Calcium; Hypertension; Iliac Artery; Norepinephrine; Potassium Chlor | 1980 |
Pressor response to 5-hydroxytryptamine, norepinephrine and KCi in the perfused hindquarter preparation from the spontaneously hypertensive rat.
Topics: Animals; Aorta, Abdominal; Blood Pressure; Hindlimb; Hypertension; Male; Methysergide; Norepinephrin | 1980 |
Cinepazet relaxation of aortic strips from normal and spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Female; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscl | 1980 |
The relationship between increased myogenic tone and hyporesponsiveness in vascular smooth muscle of spontaneously hypertensive rats.
Topics: Animals; Aorta; Calcium; Cell Membrane Permeability; Humans; Hypertension; Muscle Contraction; Muscl | 1980 |
Klotrix and other slow-release potassium tablets.
Topics: Benzothiadiazines; Costs and Cost Analysis; Delayed-Action Preparations; Diuretics; Humans; Hyperten | 1981 |
Control of hindlimb vascular resistance and vascular responsiveness in DOCA-salt hypertensive dogs.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Dogs; Female; Hindlimb; Hydralazine; Hypertension; Ma | 1981 |
Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; B | 1994 |
Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Endothelium-dependent relaxation of small arteries from essential hypertensive patients: mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats.
Topics: Acetylcholine; Adult; Animals; Apamin; Arginine; Arterioles; Charybdotoxin; Endothelium, Vascular; H | 1995 |
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1995 |
Effect of aging and hypertension on contractility of resistance arteries: modulation by endothelial factors.
Topics: Aging; Angiotensins; Animals; Arginine; Arteries; Blood Pressure; Body Weight; Endothelium, Vascular | 1995 |
Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Biological Factors; Blood Pressure; Hypertension; In Vitro | 1995 |
Age-dependent alterations in Na+, K(+)-ATPase activity in the central nervous system of spontaneously hypertensive rats: relationship to the development of high blood pressure.
Topics: Aging; Animals; Blood Pressure; Central Nervous System; Heart Rate; Hypertension; Injections, Intrav | 1995 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, | 1994 |
The mechanism of relaxation in response to magnesium by the aorta of pregnant rats with salt-induced hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Female; Hypertension; In Vitro Tech | 1995 |
The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Aorta, Thoracic; Clonidine; Dioxanes; Hypertension; In | 1995 |
Sustained hypertension in Dahl rats. Negative correlation of agonist response to blood pressure.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Mesenteric Arteries; | 1995 |
Different mechanisms of endothelial dysfunction with aging and hypertension in rat aorta.
Topics: Aging; Animals; Aorta; Blood Pressure; Body Weight; Endothelins; Endothelium, Vascular; Hypertension | 1995 |
The effects of perfusion rate and NG-nitro-L-arginine methyl ester on cirazoline- and KCl-induced responses in the perfused mesenteric arterial bed of rats.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Hype | 1994 |
High calcium diet effectively opposes the development of deoxycorticosterone-salt hypertension in rats.
Topics: Acetylcholine; Animals; Blood Pressure; Calcium; Calcium, Dietary; Cardiomegaly; Desoxycorticosteron | 1994 |
Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells.
Topics: Actin Cytoskeleton; Animals; Calcium; Cell Membrane Permeability; Colforsin; Coronary Vessels; Escin | 1994 |
Thallium poisoning from maliciously contaminated food.
Topics: Adult; Alopecia; Anemia; Antidotes; Candy; Charcoal; Chest Pain; Crime; Digestive System; Ferrocyani | 1994 |
Arterial contractions induced by cumulative addition of calcium in hypertensive and normotensive rats: influence of endothelium.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Calcium; Calcium Channels; Egtazic Acid; Endotheli | 1994 |
Impaired nitric oxide-dependent responses and their recovery in hypertensive pulmonary arteries of rats.
Topics: Animals; Body Weight; Dinoprost; Endothelium, Vascular; Hypertension; Hypertrophy, Right Ventricular | 1994 |
Stimulation of the nigrostriatal dopamine system produces hypertension and tachycardia in rats.
Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Corpus Striatum; Dopamine; D | 1994 |
Spontaneously hypertensive rats with diabetes: effects of some vasoconstrictors on isolated small arteries.
Topics: Animals; Calcium Chloride; Diabetes Mellitus, Experimental; Hypertension; In Vitro Techniques; Male; | 1993 |
Site and mechanism of behavioral tolerance to cocaine: a study of dopamine release in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Corpus Striatum; Dopamine; Drug Tolerance; Hypertension; | 1993 |
Potassium preserves endothelial function and enhances aortic compliance in Dahl rats.
Topics: Acetylcholine; Animals; Bicarbonates; Blood Pressure; Compliance; Hypertension; Male; Nitric Oxide; | 1993 |
Morphology of resistance arteries and comparison of effects of vasoconstrictors in mild essential hypertensive patients.
Topics: Adult; Angiotensin II; Arginine Vasopressin; Arteries; Endothelins; Humans; Hypertension; Hypertroph | 1993 |
Effects of quinapril, a new angiotensin-converting enzyme inhibitor, on vasoconstrictor activity in the isolated, perfused mesenteric vasculature of hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Hypertension; In Vitro Techniques; Isoquinolines; | 1993 |
Longitudinal changes during the development of hypertension in rats fed excess chloride and sodium.
Topics: Acetates; Acetic Acid; Animals; Calcium; Chlorides; Hypertension; Kidney; Magnesium; Male; Phosphoru | 1993 |
Contractile responses to various stimuli in isolated resistance vessels from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Glucose; Body Weight; Calcium Chloride; Diabetes Mellitus, | 1996 |
Angiotensin-converting enzyme inhibition attenuates arterial constrictor responses in experimental hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium; Dose-Response Relationsh | 1996 |
Vascular hyporesponsiveness in aorta from portal hypertensive rats: possible sites of involvement.
Topics: Animals; Aorta; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Muscle | 1996 |
Effect of treatment with cholecalciferol on the membrane potential and contractility of aortae from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Apamin; Cell Membrane; Cholecalciferol; Diet; Electrophysiology; Epinephri | 1996 |
Arachidonate metabolites and serotonin contraction of femoral arteries from DOCA-salt hypertensive rats.
Topics: Aluminum Compounds; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Desoxycorticosterone; Drug | 1996 |
Vascular reactivity to phenylephrine and angiotensin II in hypertensive rats associated with insulin resistance.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Fructose; Hypertension; Insulin Resistance; Male; Ph | 1996 |
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hype | 1996 |
Hypertension increases the contractions to sumatriptan in the human internal mammary artery.
Topics: Aged; Case-Control Studies; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Evaluat | 1996 |
Effect of celiprolol therapy on arterial dilatation in experimental hypertension.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Celiprolol; Cyclic AMP; Hypertension; In Vitro | 1996 |
Whey mineral supplementation and arterial tone in mineralocorticoid-NaCl hypertension.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Desoxycorticosterone; Diclofenac; Hypertension; I | 1996 |
Endothelial vasoconstrictor prostanoids modulate contractions to acetylcholine and ANG II in Ren-2 rats.
Topics: Acetylcholine; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; | 1997 |
Interaction of calcium channel blockers with different agonists in aorta from normal and diseased rats.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Calcium Channel Agonists; Calcium Channel Block | 1996 |
Internephron coupling by conducted vasomotor responses in normotensive and spontaneously hypertensive rats.
Topics: Animals; Arterioles; Blood Pressure; Body Weight; Hypertension; Male; Models, Biological; Nephrons; | 1997 |
Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension.
Topics: Acetylcholine; Animals; Aorta; Aortic Coarctation; Eflornithine; Enzyme Inhibitors; Hypertension; Mu | 1997 |
Comparison of the nitric oxide and cyclo-oxygenase pathway in mesenteric resistance vessels of normotensive and spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Blood Pressure; Cholic Acids; Hypertension; Male; Mefenamic Acid; Mesenteric | 1997 |
Responsiveness of aortic rings of cadmium-hypertensive rats to endothelin-1.
Topics: Animals; Aorta; Cadmium; Endothelin-1; Hypertension; In Vitro Techniques; Male; Norepinephrine; Pota | 1997 |
Examination by radioligand binding of the alpha1 adrenoceptors in the mesenteric arterial vasculature during the development of salt-sensitive hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Hypertension | 1997 |
Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Carbachol; Cerebrovascular Disorders; Ditioca | 1997 |
ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Endothelin Receptor Antagonists; Endothelin | 1998 |
Direct vasodepressor effects of pioglitazone in spontaneously hypertensive rats.
Topics: Animals; Arginine Vasopressin; Drug Evaluation, Preclinical; Hyperinsulinism; Hypertension; Hypoglyc | 1998 |
Prevention of renovascular and cardiac pathophysiological changes in hypertension by angiotensin II type 1 receptor antisense gene therapy.
Topics: Acetylcholine; Animals; Animals, Newborn; Blood Pressure; Cardiomegaly; Coronary Vessels; DNA, Antis | 1998 |
Influence of dietary salts on the cardiovascular effects of low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pre | 1998 |
The relaxing effect of BDF 9148 on the KCl-contracted aorta isolated from normo- and hyper-tensive rats.
Topics: Aging; Animals; Aorta, Thoracic; Azetidines; Calcium Channel Blockers; Cardiotonic Agents; Electroph | 1998 |
Coronary vascular reactivity is improved by endothelin A receptor blockade in DOCA-salt hypertensive rats.
Topics: Animals; Atrasentan; Blood Pressure; Coronary Vessels; Desoxycorticosterone; Dose-Response Relations | 1998 |
[Comparison of extra renal potassium management in hypertensive, diabetic and normal subjects].
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Humans; Hypertension; Middle Aged; Potassium; Potassium Chlo | 1997 |
Antihypertensive action of trandolapril and verapamil in spontaneously hypertensive rats after unilateral nephrectomy.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Female; Heart; Hypertension; | 1998 |
A 3 year, prospectively-designed study of late selective multifetal pregnancy reduction.
Topics: Abortion, Spontaneous; Birth Weight; Chorioamnionitis; Chromosome Aberrations; Congenital Abnormalit | 1998 |
Consumption of electrolytes and quinine by mouse strains with different blood pressures.
Topics: Animals; Benzoquinones; Blood Pressure; Body Weight; Calcium Chloride; Drinking Behavior; Female; Hy | 1998 |
Angiotensin II type 1 receptor antisense gene therapy prevents altered renal vascular calcium homeostasis in hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Calcium; Cells, Cultured; DNA, Antisense; Genet | 1999 |
U46619-mediated vasoconstriction of the fetal placental vasculature in vitro in normal and hypertensive pregnancies.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Antihypertens | 1999 |
Losartan and enalapril therapies enhance vasodilatation in the mesenteric artery of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diclofenac; Enalapril; Endothelium; E | 1999 |
Nitric oxide-dependent vasodilator mechanism is not impaired by hypertension but is diminished with aging in the rat aorta.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Biological Factors; Blood Pressure; Body Weight; Eic | 1999 |
Insulin-induced endothelin release and vasoreactivity in hypertriglyceridemic and hypertensive rats.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Azepines; Endothelin-1; Glucose Tolerance Test; | 1999 |
Selective increase of the contractile response to endothelin-1 in subcutaneous arteries from patients with essential hypertension.
Topics: Acetylcholine; Aged; Arteries; Endothelin-1; Female; Humans; Hypertension; In Vitro Techniques; Male | 1999 |
Cholesterol enhances contractile responses in isolated small mesenteric arteries of normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cholesterol; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; | 1999 |
Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2000 |
Cardiac and vascular responses in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Calcium Chloride; Carbachol; Colforsin; Desoxycorticostero | 2000 |
Effect of aspirin on the contractility of aortic smooth muscle and the course of blood pressure development in male spontaneously hypertensive rats.
Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Blood Pressure; Calcium; Calcium Signaling; Cell Membran | 1998 |
Acute and chronic sympathoinhibition on carotid artery diameter of spontaneously hypertensive rats: effects of clonidine and flesinoxan.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; A | 2000 |
Influence of enalapril on the endothelial function of DOCA-salt hypertensive rats.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Th | 2000 |
High-calcium diet enhances vasorelaxation in nitric oxide-deficient hypertension.
Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium, Di | 2000 |
Mice with disrupted BK channel beta1 subunit gene feature abnormal Ca(2+) spark/STOC coupling and elevated blood pressure.
Topics: Animals; Calcium Signaling; Cells, Cultured; Cerebral Arteries; Female; Gene Targeting; Homozygote; | 2000 |
Increased dilator response to heptanol and octanol in aorta from DOCA-salt-hypertensive rats.
Topics: Animals; Aorta; Desoxycorticosterone; Dose-Response Relationship, Drug; Heptanol; Hypertension; In V | 2001 |
Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Disease Models, Animal; D | 2001 |
Pulse pressure, aortic reactivity, and endothelium dysfunction in old hypertensive rats.
Topics: Aging; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Carbachol; Carotid Arteries; Dose-Response R | 2001 |
Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat.
Topics: Animals; Bicarbonates; Blood Pressure; Chlorides; Creatinine; Disease Susceptibility; Hypertension; | 2001 |
Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Animals; Arginine; Blood Pressure; Body Weight; Epoprostenol; H | 2000 |
Vascular changes in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Blood Vessels; Cells, Cultured; Cyclosporine; Hear | 2001 |
Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Blood Pressure; Body Weight; Dinoprost; Endothelium, Va | 2001 |
Long-term effect of bilateral ovariectomy on endothelial function in aortic rings of spontaneously hypertensive rats: role of nitric oxide.
Topics: Acetylcholine; Animals; Aorta; Blood Pressure; Body Weight; Endothelium, Vascular; Enzyme Inhibitors | 2001 |
Cysteinyl leukotrienes mediate enhanced vasoconstriction to angiotensin II but not endothelin-1 in SHR.
Topics: Angiotensin II; Animals; Benzoquinones; Endothelin-1; Hypertension; Leukotriene Antagonists; Leukotr | 2001 |
Impaired insulin-like growth factor I vasorelaxant effects in hypertension.
Topics: Animals; Aorta; Culture Techniques; Endothelins; Endothelium, Vascular; Hypertension; Insulin-Like G | 2001 |
Endothelin 1 type a receptor antagonism prevents vascular dysfunction and hypertension induced by 11beta-hydroxysteroid dehydrogenase inhibition: role of nitric oxide.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Acetylcholine; Animals; Blood Pressure; Body Weight; Cells, C | 2001 |
Blood pressure and vascular reactivity to endothelin-1, phenylephrine, serotonin, KCl and acetylcholine following chronic alcohol consumption in vitro.
Topics: Acetylcholine; Alcohol Drinking; Alcohol-Induced Disorders; Animals; Aorta; Blood Pressure; Endothel | 2001 |
Influence of lead on rat thoracic aorta contraction and relaxation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium; Disease Models, Animal; Dose-Response Relationship | 2001 |
Enhanced relaxation to the rho-kinase inhibitor Y-27632 in mesenteric arteries from mineralocorticoid hypertensive rats.
Topics: Amides; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperten | 2001 |
Enhanced contraction to 5-hydroxytryptamine is not due to "unmasking" of 5-hydroxytryptamine(1b) receptors in the mesenteric artery of the deoxycorticosterone acetate-salt rat.
Topics: Animals; Benzamides; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Hyperte | 2001 |
Maturation reveals a decrease in endothelium-dependent contraction induced by depolarization in the aorta of spontaneously hypertensive rats.
Topics: Aging; Animals; Aorta; Aspirin; Biphenyl Compounds; Body Weight; Endothelium, Vascular; Heptanoic Ac | 2001 |
Influence of aldosterone vs. endothelin receptor antagonism on renovascular function in liquorice-induced hypertension.
Topics: Animals; Blood Vessels; Endothelin Receptor Antagonists; Endothelium, Vascular; Glycyrrhiza; Glycyrr | 2001 |
Effect of high extracellular Ca(2+) levels in spontaneously hypertensive rat aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Dihydropyridines; Dose-Response Relationship, Drug; Endothelium, | 2001 |
Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Female; Hypertensi | 2002 |
Influence of hypertension on acetaldehyde-induced vasorelaxation in rat thoracic aorta.
Topics: Acetaldehyde; Animals; Aorta, Thoracic; Endothelium, Vascular; Histamine; Hypertension; In Vitro Tec | 2002 |
Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt-hypertensive rats.
Topics: Animals; Desoxycorticosterone; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; In Vitro | 2002 |
Cellular basis for increased sensitivity of vascular smooth muscle in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Arteries; Cells, Cultured; Chickens; Hypertension; Membrane Potentials; Musc | 1976 |
Effects of chlorthalidone on serum and total body potassium in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Body Weight; Chlorthalidone; Drug Therapy, Combination; Electrolytes | 1976 |
Letter: Hyponatraemia and diuretics.
Topics: Aged; Body Weight; Diuretics; Humans; Hypertension; Hyponatremia; Polythiazide; Potassium; Potassium | 1975 |
Letter: Potassium stricture of the upper alimentary tract.
Topics: Aged; Female; Humans; Hypertension; Ileum; Intestinal Obstruction; Male; Middle Aged; Potassium Chlo | 1976 |
Inappropriate antihypertensive therapy in the elderly.
Topics: Age Factors; Aged; Antihypertensive Agents; Cyclopenthiazide; Drug Therapy, Combination; Humans; Hyp | 1976 |
Drug-associated primary acute pancreatitis.
Topics: Acute Disease; Aged; Cyclopenthiazide; Drug Therapy, Combination; Furosemide; Humans; Hypertension; | 1978 |
Vascular responsiveness to norepinephrine, serotonin, and potassium chloride in veins from spontaneously hypertensive and age-matched Wistar Kyoto rats.
Topics: Animals; Aorta; Hypertension; In Vitro Techniques; Isoproterenol; Jugular Veins; Male; Nitroglycerin | 1979 |
Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Cir | 1978 |
When salt substitutes are required in low-sodium diets.
Topics: Diet, Sodium-Restricted; Food Additives; History, 19th Century; History, 20th Century; History, Anci | 1978 |
Differential response of hamster cheek pouch microvessels to vasoactive stimuli during the early development of hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cheek; Cricetinae; Hypertension; Norepinephrine | 1979 |
Factors influencing serum potassium in treated hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Creatinine; Diuretics; Female; Humans; Hypertension; Hypokalemia; | 1977 |
[Increased sensitivity of vascular muscles in renal and corticosterone hypertension].
Topics: Animals; Blood Vessels; Catechol O-Methyltransferase; Corticosterone; Hypertension; Methoxamine; Mus | 1977 |
Potassium-level changes during long-term thiazide therapy.
Topics: Heart Failure; Humans; Hypertension; Hypokalemia; Magnesium; Potassium; Potassium Chloride; Spironol | 1978 |
Dithiothreitol-induced alterations of blood pressure, vascular reactivity and aortic microsomal calcium uptake in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Calcium; Dithionitrobenzoic Acid; Dithiothreitol; Female; Hypertensi | 1978 |
Increased renal vascular reactivity to norepinephrine in stroke-prone spontaneously hypertensive rat (SHR).
Topics: Angiotensin II; Animals; Cerebrovascular Disorders; Hypertension; In Vitro Techniques; Kidney; Male; | 1978 |
Role of the thyroid gland in the development and maintenance of spontaneous hypertension in rats.
Topics: Age Factors; Animals; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Heart Rate; Hyp | 1977 |
Increased monoamine oxidase activity in cardiovascular and central nervous systems of DOCA-NaCl hypertensive rabbits.
Topics: Animals; Arteries; Desoxycorticosterone; Female; Hypertension; Hypothalamus; Male; Monoamine Oxidase | 1977 |
The action of diazoxide analogs on aortic reactivity in normotensive and spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Benzothiadiazines; Blood Vessels; Diazoxide; Drug Interactions; Hypertensi | 1977 |
Diuretics and potassium metabolism: a reassessment of the need, effectiveness and safety of potassium therapy.
Topics: Acid-Base Equilibrium; Adult; Diuretics; Edema; Female; Humans; Hypertension; Hypokalemia; Kidney Tu | 1977 |
Effects of diuretics on lipid metabolism in patients with essential hypertension.
Topics: Adult; Blood Glucose; Cholesterol; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; | 1976 |
Hypertension, transmural pressure, and vascular smooth muscle response in rats.
Topics: Animals; Arteries; Calcium; Calcium Chloride; Desoxycorticosterone; Disease Models, Animal; Epinephr | 1975 |
Letter: Potassium in salt substitutes.
Topics: Adult; Costs and Cost Analysis; Diet, Sodium-Restricted; Female; Humans; Hyperkalemia; Hypertension; | 1975 |
Role of saline consumption in the prevention of deoxycorticosterone hypertension in rats by central 6-hydroxydopamine.
Topics: Animals; Blood Pressure; Brain; Desoxycorticosterone; Dopamine; Drinking Behavior; Feeding Behavior; | 1975 |
Sodium restriction and thiazide diuretics in the treatment of hypertension.
Topics: Amiloride; Bicarbonates; Body Weight; Chlorothiazide; Diet, Sodium-Restricted; Diuretics; Humans; Hy | 1975 |
Verapamil and diazoxide antagonism of agonist-induced contractions of aortic strips from normal and spontaneously hypertensive rats (SHR).
Topics: Animals; Aorta, Thoracic; Diazoxide; Hypertension; In Vitro Techniques; Methoxamine; Muscle Contract | 1975 |
The effect of salt intake and adrenal steroids on blood pressure in a genetic strain of hypertensive rats.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Animals; Blood Pressure; Corticosterone; Die | 1975 |
Vasodilator responses to K+ in genetic hypertensive and in renal hypertensive rats.
Topics: Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Hypertension; Hypertension, | 1975 |
Salt and the development of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diet, Sodium-Restricted; Dose-Response Relationship, | 1976 |
Diuretic induced hyponatraemia in the elderly.
Topics: Aged; Diagnosis, Differential; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; H | 1992 |
Arterial smooth muscle contractions in spontaneously hypertensive rats on a high-calcium diet.
Topics: Analysis of Variance; Animals; Blood Platelets; Blood Pressure; Calcium; Calcium, Dietary; Dose-Resp | 1992 |
Cardiovascular effects of substituted tetrahydroisoquinolines in rats.
Topics: Alkaloids; Animals; Aorta; Benzylisoquinolines; Blood Pressure; Calcium Channels; Cerebral Cortex; D | 1992 |
Effect of aspirin on the contractility of aortic smooth muscle in female spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Aspirin; Blood Pressure; Clonidine; Female; Hypertension; | 1992 |
Intraluminal pressure modulates vascular contractility of perfused mesenteric resistance arteries. Altered response in hypertension.
Topics: Animals; Blood Pressure; Humans; Hypertension; Male; Mesenteric Arteries; Perfusion; Potassium Chlor | 1992 |
Effect of dietary potassium chloride in borderline hypertensive rats.
Topics: Animals; Blood Pressure; Diet; Efferent Pathways; Heart Rate; Hypertension; Kidney; Male; Potassium | 1992 |
[Genetic analysis of various behavioral and physiologic characteristics in hybrids between hypertensive and normotensive rats. Analysis of reciprocal differences].
Topics: Animals; Choice Behavior; Crosses, Genetic; Female; Genetic Linkage; Hybridization, Genetic; Hyperte | 1992 |
[Genetic analysis of various behavioral and physiologic characteristics in hybrids between hypertensive and normotensive rats. Analysis of correlational connections].
Topics: Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Body Weight; Choice Behavior; Crosses | 1992 |
[Therapy of hypokalemia associated with hypertension].
Topics: Animals; Antihypertensive Agents; Diuretics; Humans; Hypertension; Hypokalemia; Potassium Chloride | 1992 |
Enhanced release of endothelium-derived relaxing factor in mineralocorticoid hypertension.
Topics: Animals; Arginine Vasopressin; Arteries; Blood Pressure; Desoxycorticosterone; Endothelium, Vascular | 1992 |
Antihypertensive effect of the new calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl-methyl-4-(2-fluoro-5- nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate hydrochloride in rats.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Desoxyc | 1992 |
Age-dependent changes in afferent renal nerve activity in genetically hypertensive rats.
Topics: Afferent Pathways; Aging; Animals; Chemoreceptor Cells; Electrophysiology; Enalapril; Hypertension; | 1992 |
Neurovascular function during pregnancy in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiovascular System; Electric Stimulation; Female; Hypertension; Methoxyh | 1992 |
Effects of endothelin on resistance arteries of DOCA-salt hypertensive rats.
Topics: Animals; Arginine Vasopressin; Desoxycorticosterone; Endothelins; Endothelium, Vascular; Histologica | 1992 |
Increased vascular reactivity to Bay K 8644 in genetic hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
High calcium diet augments vascular potassium relaxation in hypertensive rats.
Topics: Animals; Calcium, Dietary; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Ma | 1992 |
Calcium and the impairment of contractions to norepinephrine in aorta isolated from the spontaneously hypertensive rat.
Topics: Animals; Aorta, Thoracic; Calcium; Egtazic Acid; Hypertension; In Vitro Techniques; Male; Muscle Con | 1991 |
Vascular reactivity in isolated lungs of rats with spontaneous systemic hypertension.
Topics: Analysis of Variance; Animals; Hemodynamics; Hypertension; In Vitro Techniques; Lung; Male; Oxygen; | 1991 |
Specific supersensitivity of the mesenteric vascular bed of Dahl salt-sensitive rats.
Topics: Acetylcholine; Animals; Blood Pressure; Cocaine; Dose-Response Relationship, Drug; Electric Stimulat | 1991 |
[Experiences with isolated organ studies on pathological human arteries].
Topics: Adult; Aged; Arteries; Arteriosclerosis Obliterans; Diabetic Angiopathies; Dinoprost; Female; Femora | 1991 |
Effects of bepridil compared to those of its quaternary analogue on femoral arteries from spontaneously hypertensive rats.
Topics: Animals; Bepridil; Caffeine; Calcium Chloride; Femoral Artery; Hypertension; Male; Muscle Contractio | 1990 |
Enhanced induction of gastric carcinogenesis by N-methyl-N'-nitro-N-nitrosoguanidine in deoxycorticosterone acetate-NaCl hypertensive rats and its inhibition by potassium chloride.
Topics: Adenocarcinoma; Animals; Desoxycorticosterone; Drug Interactions; Gastric Mucosa; Hypertension; Male | 1991 |
Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; | 1990 |
Increased sensitivity to noradrenaline in glucocorticoid-treated rats: the effects of indomethacin and desipramine.
Topics: Animals; Blood Pressure; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Hypertension; | 1990 |
Vascular hypertrophy, renin and blood pressure in the young spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Norepinephrine; Potas | 1990 |
Reactivity and sensitivity of mesenteric vascular beds and aortic rings of spontaneously hypertensive rats to endothelin: effects of calcium entry blockers.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Endothelins; Hypertension; In Vitro Techniques; | 1990 |
Structural and functional alterations of mesenteric vascular beds in spontaneously hypertensive rats.
Topics: Analysis of Variance; Animals; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, | 1990 |
Effects of vasoactive agents on isolated human umbilical veins in preeclamptic women.
Topics: Adult; Female; Fetal Growth Retardation; Humans; Hypertension; Infant, Newborn; Muscle Contraction; | 1990 |
Antihypertensive and adverse biochemical effects of bendrofluazide.
Topics: Bendroflumethiazide; Humans; Hypertension; Potassium Chloride | 1990 |
Calcium antagonists inhibit elevated potassium efflux from aorta of aldosterone-salt hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Diltiazem; Hypertension; In Vitro Te | 1990 |
Potassium channels and vascular reactivity in genetically hypertensive rats.
Topics: Animals; Barium; Blood Vessels; Female; Hypertension; Male; Potassium Channels; Potassium Chloride; | 1990 |
Effects of Bay K 8644 and nifedipine on femoral arteries of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Sodium pump activity and calcium relaxation in vascular smooth muscle of deoxycorticosterone acetate-salt rats.
Topics: Animals; Calcium; Calcium Chloride; Femoral Artery; Hypertension; Ion Channels; Male; Muscle Contrac | 1986 |
Abnormalities in the hypothalamo-pituitary-adrenal axis in spontaneously hypertensive rats during development of hypertension.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Blood Pressure; Body Weig | 1989 |
Abnormal contractile response of aortas from spontaneously hypertensive rats to Ca2+ after depletion of Ca2+ in Ca2+-free medium.
Topics: Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; | 1989 |
[The salt appetite of rats with spontaneous arterial hypertension].
Topics: Animals; Appetite; Calcium Chloride; Drinking; Female; Food Preferences; Hypertension; Male; Potassi | 1989 |
(Na+ + K+) ATPase inhibitors and intracellular electrolytes in essential hypertension.
Topics: Humans; Hydrochlorothiazide; Hypertension; Leukocytes; Male; Potassium; Potassium Chloride; Renin; S | 1987 |
Calcium transport in basolateral plasma membranes from kidney cortex of Milan hypertensive rats.
Topics: Adenosine Triphosphate; Aging; Animals; Biological Transport, Active; Calcium; Calcium-Transporting | 1988 |
Compliance and the elderly hypertensive.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Drug | 1986 |
Changes in myocardial distensibility in rat papillary muscle: fibrosis, KCl contracture, hypoxic contracture, oxygen and glucose deficiency contracture, and experimental tetanus.
Topics: Animals; Cardiomegaly; Diastole; Glucose; Heart; Hypertension; Hypertension, Renovascular; Hypoxia; | 1987 |
Inadvertent epidural administration of potassium chloride. A case report.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Female; Fentanyl; Humans; Hy | 1988 |
[Transmembrane potential and electrogenicity of thrombocyte Na, K-ATPase in different forms of hypertension in rats].
Topics: Animals; Blood Platelets; Desoxycorticosterone; Hypertension; Hypertension, Renal; Male; Membrane Po | 1985 |
Diminished beta-adrenoceptor-mediated relaxation of arteries from spontaneously hypertensive rats before and during development of hypertension.
Topics: Albuterol; Animals; Arteries; Dinoprost; Hydroxydopamines; Hypertension; Isoproterenol; Male; Nitrop | 1987 |
[The effect of NaCl and KCl administration on median blood pressure, body weight, the ionogram of saliva, serum and urine and plasma renin activity in healthy persons and stage I hypertensive patients].
Topics: Adolescent; Adult; Blood Pressure; Body Weight; Female; Humans; Hypertension; Male; Potassium; Potas | 1988 |
The effect of plasma from patients with essential hypertension on the contractility of human arteries.
Topics: Female; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Sm | 1988 |
Vascular changes during calcium loading in experimental hypertension.
Topics: Animals; Aorta, Thoracic; Calcitriol; Calcium, Dietary; Hypertension; In Vitro Techniques; Male; Mes | 1988 |
[Versatility of arterial and venous responses to the action of physiologic stimuli in rats with DOCA-salt hypertension].
Topics: Animals; Desoxycorticosterone; Electric Stimulation; Hypertension; Kidney; Male; Mesenteric Arteries | 1988 |
Zona glomerulosa function after life-long suppression in two siblings with the hypertensive virilizing form of congenital adrenal hyperplasia.
Topics: 18-Hydroxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Aldosterone; | 1988 |
Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Calcium Channel Blockers; Drug Evaluation; | 1987 |
Bile acids are able to reduce blood pressure by attenuating the vascular reactivity in spontaneously hypertensive rats.
Topics: Animals; Bile Acids and Salts; Blood Pressure; Blood Vessels; Deoxycholic Acid; Glycodeoxycholic Aci | 1988 |
Area postrema ablation and vascular reactivity in deoxycorticosterone-salt-treated rats.
Topics: Animals; Arteries; Blood Pressure; Desoxycorticosterone; Drug Synergism; Hypertension; Isometric Con | 1988 |
Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.
Topics: Animals; Arteries; Blood Proteins; Cardenolides; Digoxin; Dogs; Ear, External; Epinephrine; Humans; | 1987 |
Changes in aortic water and sodium contents associated with potassium supplement in DOCA-salt rats.
Topics: Animals; Aorta, Abdominal; Blood Pressure; Body Weight; Drinking Behavior; Hypertension; Potassium C | 1986 |
Sodium and potassium intake in the management of high blood pressure.
Topics: Combined Modality Therapy; Diet, Sodium-Restricted; Double-Blind Method; Humans; Hypertension; Potas | 1986 |
Vascular reactivity in the spontaneously hypertensive stroke-prone rat. Effect of antihypertensive treatment.
Topics: Animals; Blood Pressure; Calcium; Cerebrovascular Disorders; Female; Femoral Artery; Hydralazine; Hy | 1987 |
[Feasibility of a program of moderate restriction of sodium using salt with low contents of sodium and dietetic prescriptions].
Topics: Adolescent; Adult; Blood Pressure; Calcium Carbonate; Citrates; Citric Acid; Diet, Sodium-Restricted | 1987 |
[Effect of potassium chloride on the circulatory system of persons with hypertension and hypertensive reactions in load tests].
Topics: Blood Circulation; Blood Pressure; Climacteric; Female; Humans; Hypertension; Neurocirculatory Asthe | 1987 |
Comparative studies of reduced sodium and high potassium diet in hypertension.
Topics: Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Potassium Chloride; Sodium, Dietary | 1987 |
Extracellular calcium and altered vascular responsiveness in the deoxycorticosterone acetate-salt rat.
Topics: Animals; Calcium; Desoxycorticosterone; Dose-Response Relationship, Drug; Extracellular Space; Femor | 1986 |
Role of potassium in mild and moderate essential hypertension.
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Potassium Chloride | 1986 |
Potassium supplementation in essential hypertension.
Topics: Humans; Hypertension; Potassium Chloride | 1986 |
The effect of sodium depletion and potassium loading on cortisol induced hypertension in sheep.
Topics: Animals; Female; Hemodynamics; Hydrocortisone; Hypertension; Infusions, Intravenous; Potassium Chlor | 1986 |
Altered aortic reactivity and lowered blood pressure associated with high calcium intake.
Topics: Animals; Aorta; Blood Pressure; Calcium, Dietary; Dose-Response Relationship, Drug; Elasticity; Hype | 1986 |
Differential effects of phentolamine on the responsiveness of aortic and femoral smooth muscle from normotensive and DOCA/NaCl hypertensive rats.
Topics: Animals; Aorta; Desoxycorticosterone; Femoral Artery; Hypertension; In Vitro Techniques; Isoproteren | 1986 |
Perfusion of the intact and partially isolated rat mesenteric vascular bed: application to vessels from hypertensive and normotensive rats.
Topics: Animals; Blood Pressure; Cocaine; Hypertension; Male; Mesenteric Arteries; Norepinephrine; Perfusion | 1986 |
Calcium influx and vascular reactivity in systemic hypertension.
Topics: Animals; Calcium; Hypertension; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; P | 1987 |
Cerebral vascular responsiveness in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Basilar Artery; Blood Pressure; Calcium; Cerebrovascular Circulation; Desoxycorticosterone; | 1987 |
Attenuation of alpha-adrenergic responsiveness in hypoxic SHR.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Hy | 1986 |
Hypotensive mechanism of potassium supplementation in salt-loaded patients with essential hypertension.
Topics: Blood Pressure; Diet, Sodium-Restricted; Dinoprostone; Female; Hormones; Humans; Hypertension; Hypot | 1985 |
Essential hypertension: a metabolic cause? A hypothesis.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Calcium; Captopril; Female; Humans; Hydrochlorothiazide; H | 1985 |
Salt substitute as potassium replacement in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Diet; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia | 1986 |
Impaired baroreflex sensitivity in the aetiology of salt hypertension in the rabbit.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Disease Susceptibility; Female; Heart Rate; Hypertens | 1985 |
Dietary sodium/potassium ratio in salt substitute and its putative significance in essential hypertension.
Topics: Carbonates; Humans; Hypertension; Plants, Edible; Potassium Chloride; Sodium | 1985 |
Renal tubular function in essential hypertension in Nigerians--its relationship to plasma protein.
Topics: Adult; Female; Humans; Hypertension; Kidney Concentrating Ability; Kidney Tubules; Male; Middle Aged | 1985 |
[Optimal method of the hypotensive treatment of hypertension with diuretics and sodium chloride substitutes].
Topics: Adult; Aged; Blood Pressure; Clopamide; Diet, Sodium-Restricted; Diuresis; Dose-Response Relationshi | 1985 |
Total-body potassium in hypertension patients during prolonged diuretic therapy.
Topics: Adult; Aged; Body Weight; Diuretics; Female; Humans; Hypertension; Long-Term Care; Male; Middle Aged | 1972 |
Editorial: Slow-K, quick quick, slow.
Topics: Death, Sudden; Diuretics; Edema; Heart Diseases; Humans; Hyperkalemia; Hypertension; Hypokalemia; Po | 1974 |
Letter: Potassium supplements.
Topics: Bendroflumethiazide; Drug Therapy, Combination; Humans; Hyperkalemia; Hypertension; Potassium; Potas | 1974 |
Effects of sodium intake on inherited hypertension in the rat.
Topics: Alleles; Animals; Blood Pressure; Diet, Sodium-Restricted; Hypertension; Male; Potassium Chloride; R | 1971 |
Proceedings: General practitioner studies of beta-blockade in hypertension.
Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Cyclic S-Oxides; Cyclopentanes; Diuretics; Drug Syne | 1974 |
Differences in papaverine inhibition of prostaglandin-induced contraction of aortic strips from normal and spontaneously hypertensive rats (SHR).
Topics: Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Muscle Contraction; Mus | 1974 |
[Hyperglycemic actions of potassium, rubidium and cesium ions compared to their hypertensive actions].
Topics: Animals; Cesium; Dogs; Hyperglycemia; Hypertension; Potassium; Potassium Chloride; Rubidium | 1967 |
A consideration of a mechanism of hypertension through effects of ions upon the contractility arterial tissue and its contractile protein.
Topics: Actins; Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arteries; Ascorbic A | 1972 |
Deoxycorticosterone acetate hypertension in dogs.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Dogs; Glomerulonephritis; Hypertension; Potassium Chl | 1965 |
Thallium poisoning.
Topics: Adult; Alopecia; Child; Child, Preschool; Humans; Hypertension; Male; Peripheral Nervous System Dise | 1972 |
Reactivity of vascular smooth muscle in hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Body Weight; Calcium; Cell Membrane; Desoxycortic | 1973 |
[Thiazide saluretics and glucose tolerance in patients with hypertension].
Topics: Blood Glucose; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Potassium Chloride | 1974 |
Red blood cell potassium as a measure of body potassium in thiazide-treated patients with essential hypertension.
Topics: Depression, Chemical; Drug Therapy, Combination; Erythrocytes; Female; Hematocrit; Humans; Hydrochlo | 1974 |
Electrical property of cardiac cell membrane of spontaneously hypertensive rat.
Topics: Acetylcholine; Action Potentials; Animals; Atrial Function; Cell Membrane; Depression, Chemical; Ele | 1974 |
Management of potassium problems during long-term diuretic therapy.
Topics: Aldosterone; Diet; Diuretics; Extracellular Space; Homeostasis; Humans; Hydrogen-Ion Concentration; | 1974 |
Contractile response of the aorta of the normotensive and acute and chronic hypertensive rat.
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Aorta; Blood Pressure; Calcium; Chronic Disease; Dose-R | 1973 |
Attenuated vasodilator responses to K+ in essential hypertensive men.
Topics: Adult; Blood Pressure; Brachial Artery; Humans; Hypertension; Hypertension, Renal; Indicator Dilutio | 1974 |
A comparison of moduretic and hydrochlorothiazide in the treatment of hypertension in African patients.
Topics: Adult; Aged; Amiloride; Blood Pressure; Diuretics; Electrolytes; Female; Humans; Hydrochlorothiazide | 1973 |
[Electrolyte metabolism in patients with hypertensive disease treated with hyparez].
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothi | 1973 |
Adverse reactions to spironolactone. A report from the Boston Collaborative Drug Surveillance Program.
Topics: Adult; Aged; Blood Urea Nitrogen; Coma; Dehydration; Diarrhea; Female; Gynecomastia; Headache; Heart | 1973 |
Studies on the contractile effects of prostaglandins on aortic strip preparations from spontaneously hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Muscle Contraction; Mus | 1973 |
Potassium-induced bowel ulceration.
Topics: Aged; Delayed-Action Preparations; Female; Humans; Hypertension; Intestinal Diseases; Potassium Chlo | 1974 |
Influence of dietary potassium and sodium/potassium molar ratios on the development of salt hypertension.
Topics: Analysis of Variance; Animals; Blood Pressure; Diet; Hypertension; Male; Osmolar Concentration; Pota | 1972 |
[Clinical trial of a new drug with hypotensive action].
Topics: Aged; Benzothiadiazines; Carbamates; Drug Synergism; Female; Heterocyclic Compounds; Humans; Hyperte | 1971 |
Vascular reactivity in 'post-DOCA' hypertension.
Topics: Acetates; Animals; Arteries; Desoxycorticosterone; Hypertension; Injections, Intramuscular; Male; Ne | 1971 |
Vascular smooth muscle reactivity in normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Isoproterenol; Muscle Contraction; Muscle, S | 1969 |
[Clinical evaluation of the potassium chloride and Gynergen tests for the differentiation of the changes of heart repolarization in the electrocardiogram].
Topics: Adolescent; Adult; Aged; Coronary Disease; Diagnosis, Differential; Electrocardiography; Ergonovine; | 1969 |
[Anti-hypertensive therapy in geriatrics].
Topics: Age Factors; Aged; Antihypertensive Agents; Carbamates; Drug Synergism; Female; Humans; Hydrazines; | 1970 |
Regulation of vascular smooth muscle contraction. Changes in experimental hypertension.
Topics: Adenosine Triphosphate; Animals; Blood Vessels; Calcium; Desoxycorticosterone; Epinephrine; Femoral | 1970 |
Relationship of sodium and potassium intake to blood pressure.
Topics: Blood Pressure; Body Weight; Edema; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Potassiu | 1971 |
[A study of various indices of the functional state of the adrenal cortex and mineral metabolism in patients with hypertension during potassium chloride loading].
Topics: Adrenal Glands; Adult; Humans; Hypertension; Middle Aged; Pituitary-Adrenal Function Tests; Potassiu | 1967 |
[Complex treatment of patients with hypertension].
Topics: Adult; Aged; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Potassium Chl | 1967 |
[Treatment of essential arterial hypertension by a major hypotensive combination without hypotensive drugs].
Topics: Aged; Diuretics; Humans; Hypertension; Methotrimeprazine; Potassium Chloride | 1967 |
Suppressive effect of potassium on renin release.
Topics: Chlorothiazide; Depression, Chemical; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hypertens | 1968 |
Mechanisms of intra-arterial Kplus-induced cardiovascular and respiratory responses.
Topics: Animals; Blood Pressure; Chlorisondamine; Dogs; Femoral Artery; Heart; Heart Rate; Hindlimb; Hyperte | 1969 |
[Treatment of essential hypertension with potassium chloride].
Topics: Adult; Aged; Humans; Hypertension; Middle Aged; Potassium Chloride | 1965 |
[Clinical trials of a new antihypertensive drug association in aged subjects. Behavior of the electrolyte pattern].
Topics: Aged; Carbamates; Electrolytes; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Potassium Ch | 1966 |
[Effect of trichlormethiazide and triamterene on blood pressure, serum electrolytes and erythrocyte sodium].
Topics: Electrolytes; Erythrocytes; Female; Humans; Hypertension; Male; Potassium Chloride; Sodium; Triamter | 1966 |
[Geriatric contribution to the treatment of hypertension (excluding reserpine)].
Topics: Aged; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Phytotherapy; Plants, Medicinal; Pota | 1966 |
[The influence of combined Rauwolfia-saluretic therapy on the hemodynamics of hypertensive patients].
Topics: Adult; Aged; Diuretics; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Middle Aged; Phytot | 1966 |
The mesorchium vessel reactivity to catecholamines in rats with experimental hypertension.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Ephedrine; Epinephrine; Hypertension; Hypertension, R | 1966 |
[On the antihypertensive activity of some drugs alone or in various associations].
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Carbamates; Female; Humans; Hydrazines; Hydr | 1966 |