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potassium chloride and Disease Models, Animal

potassium chloride has been researched along with Disease Models, Animal in 245 studies

Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368."7.91Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019)
"To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats."7.78The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012)
"St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats."7.76Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010)
"To observe and compare the effect of taurine on contractions of aortic rings isolated from normal (NC) and insulin resistance (IR) Sprague-Dawley rats, and to explore its underlying mechanism(s)."7.74Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed. ( Li, J; Liang, Y; Niu, L; Wu, D; Xue, W; Zhang, M, 2008)
"In the fetal rat, nitrofen induces congenital diaphragmatic hernia (CDH) and pulmonary vascular remodeling similar to what is observed in the human condition."7.72Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model. ( Belik, J; Davidge, ST; Greer, JJ; Pan, J; Zhang, W, 2003)
" Common factors were hyperkalemia and verapamil therapy."7.68Effect of hyperkalemia on experimental myocardial depression by verapamil. ( Jolly, SR; Keaton, N; Movahed, A; Reeves, WC; Rose, GC, 1991)
"The treatment with agmatine appeared to be significantly effective in reducing the MDA content and MPO activity besides restoring the content of GSH."5.46Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats. ( Araslı, M; Barut, F; Ozacmak, HS; Ozacmak, VH; Turan, I, 2017)
"In a pig model of untreated VF cardiac arrest for 14 minutes, resuscitation with potassium/lidocaine-induced cardiac standstill during conventional CPR tended to reduce myocardial injury and decreased the severity of postresuscitation myocardial dysfunction significantly."5.40Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation. ( Heo, T; Hun Jung, Y; Il Min, Y; Jeong, IS; Joon Lee, S; Kook Lee, B; Lim, V; Woon Jeung, K; Youn Lee, H, 2014)
"Potassium chloride was delivered directly into the left ventricular cavity under ultrasound guidance in intubated mice, resulting in immediate asystole."3.96A novel ultrasound-guided mouse model of sudden cardiac arrest. ( Chiba, T; Dezfulian, C; Kaufman, BA; Redding, K; Rutledge, CA; Sims-Lucas, S, 2020)
"The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368."3.91Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019)
"Sprague-Dawley(R) rats accepted bladder neck obstruction surgery or sham surgery, and then received treatment of three different antimuscarinics (Solifenacin, Darifenacin, and Tolterodine) or vehicle."3.85Protective Effects of Antimuscarinics on the Bladder Remodeling After Bladder Outlet Obstruction. ( Li, H; Liao, B; Liu, Q; Luo, D; Wang, KJ; Yang, T, 2017)
"10)kg) were divided into 4 fatal groups; drowning, hypothermia, bag suffocation, and Potassium Chloride intravenous (control) group."3.83Postmortem computed tomography findings in the thorax - Experimental evaluation. ( Hyodoh, H; Mizuo, K; Okazaki, S; Rokukawa, M; Shimizu, J; Watanabe, S, 2016)
" Intraperitoneal injection of KCl in zebrafish induced an arrhythmia similar to that of humans, and the arrhythmia was partially rescued by calcium gluconate."3.83Improvement of surface ECG recording in adult zebrafish reveals that the value of this model exceeds our expectation. ( Cheng, SH; Lam, YW; Li, L; Liu, CC; Siu, CW, 2016)
"Ouabain is an endogenous Na(+)/K(+)-ATPase inhibitor whose chronic administration induces hypertension."3.81Chronic ouabain treatment induces Rho kinase activation. ( Ark, M; Aypar, E; Demirtaş, A; Gözübüyük, G; Ozdemir, A; Şahan, G; Turan, NN, 2015)
" A preventive effect on ovalbumin (OVA)-induced bronchospasm was observed in sensitized guinea pigs for each androgen."3.80Androgens are bronchoactive drugs that act by relaxing airway smooth muscle and preventing bronchospasm. ( Chávez, J; Espinoza, J; Flores-Soto, E; Montaño, LM; Perusquía, M, 2014)
"To investigate a possible relation between hypercholesterolemia and detrusor smooth muscle function, we studied the contractile response to potassium challenge, carbachol (CCh), and the components of CCh-induced contractile mechanism in high-cholesterol diet-fed rats."3.78The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. ( Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B, 2012)
" Metformin treatment improved the insulin sensitivity, and normalized the in vitro bladder hypercontractility and cystometric dysfunction in obese mice."3.78Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice. ( Anhê, GF; Antunes, E; Calixto, MC; De Nucci, G; Grant, AD; Leiria, LO; Lintomen, L; Mónica, FZ; Sollon, C; Zanesco, A, 2012)
" This study compared the protective effects of two widely used preservation solutions, histidine-tryptophan-ketoglutarate (HTK) and Celsior (CEL; Sangstat Medical, Menlo Park, CA), for ischemia-reperfusion injury using a rat heterotopic heart transplantation model with older donors."3.77Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors? ( Billiar, TR; Huang, CS; Kawamura, T; Lee, S; Nakao, A; Shigemura, N; Toyoda, Y, 2011)
" In the present study, we investigated changes of intracellular Ca2+ increased by potassium chloride (KCl) and phenylephrine (PE) under hyperglycemia in rat heart myoblast H9c2 cells (BCRC 60096), respectively."3.76Effect of hyperglycemia on the changes of intracellular [Ca2+]i in heart myoblast. ( Ko, WS; Lee, NY; Sun, MH, 2010)
"The physiologic response of wild-types and mice lacking both CK-B and UbCKmit (CK--/--mice) to pentylenetetrazole (PTZ)-induced seizures was measured using electroencephalography (EEG) recordings and behavioral monitoring."3.76Complete brain-type creatine kinase deficiency in mice blocks seizure activity and affects intracellular calcium kinetics. ( Oerlemans, F; Scheenen, WJ; Streijger, F; Van der Zee, CE; van Luijtelaar, G; Wieringa, B, 2010)
"St Thomas cardioplegia solution supplemented with emulsified isoflurane enhanced its cardioprotection in an isolated heart ischemia reperfusion injury model in rats."3.76Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats. ( Huang, H; Li, T; Liu, J; Liu, S; Yanfang, C; Zhang, W, 2010)
" Nutritional interventions, like potassium chloride (KCl) diet supplementation, and exercises are common nonpharmacological indications for treating hypertension."3.76Evaluation of exercise and potassium chloride supplementation on blood pressure and nociceptive threshold in hypertensive rats. ( Duarte, ID; Franca, VM; Galdino, GS; Lopes, AM; Perez, AC, 2010)
"Hyperthyroidism was induced on Wistar-Kyoto male rats with L-Thyroxine, (THYR) treatment for two weeks, N."3.75Thyroid hormone modulates the responsiveness of rat aorta to alpha1-adrenergic stimulation: an effect due to increased activation of beta2-adrenergic signaling. ( Cokkinos, DV; Karageorgiou, H; Kostopanagiotou, G; Mourouzis, I; Mourouzis, K; Pantos, C; Pappas, M; Tesseromatis, C, 2009)
"To observe and compare the effect of taurine on contractions of aortic rings isolated from normal (NC) and insulin resistance (IR) Sprague-Dawley rats, and to explore its underlying mechanism(s)."3.74Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed. ( Li, J; Liang, Y; Niu, L; Wu, D; Xue, W; Zhang, M, 2008)
" The evolution of systolic blood pressure was followed by weekly measurements, and morphological variables, proteinuria, plasma nitrates plus nitrites (NOx) and thiobarbituric acid reactive substances (TBARS), liver oxidative stress markers and endothelial function were determined at the end of the experimental period."3.73Effects of chronic quercetin treatment in experimental renovascular hypertension. ( Bermejo, A; Duarte, J; Galisteo, M; García-Saura, MF; Vargas, F; Villar, IC; Zarzuelo, A, 2005)
"Kainate-induced epilepsy has been shown to be associated with increased levels of neuropeptide Y (NPY) in the rat hippocampus."3.73Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats. ( Cavadas, C; Cristóvão, A; Ferreira, R; Grouzmann, E; Lourenço, J; Malva, JO; Oliveira, CR; Pinheiro, PS; Silva, AP; Xapelli, S, 2005)
"In the fetal rat, nitrofen induces congenital diaphragmatic hernia (CDH) and pulmonary vascular remodeling similar to what is observed in the human condition."3.72Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model. ( Belik, J; Davidge, ST; Greer, JJ; Pan, J; Zhang, W, 2003)
"Low levels of lead, but not high levels, produce hypertension."3.71Influence of lead on rat thoracic aorta contraction and relaxation. ( Gonick, HC; Shelkovnikov, SA, 2001)
"The results demonstrate that the rate of contractile failure induced by in vitro ischemia is greater than that induced by in vitro hypoxia, and that the contractile response to FS is significantly more sensitive to both hypoxia and in vitro ischemia than is the contractile response to either carbachol or KCl."3.70Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation. ( Horan, P; Levin, RM; Liu, SP; Ohnishi, N, 1998)
" Common factors were hyperkalemia and verapamil therapy."3.68Effect of hyperkalemia on experimental myocardial depression by verapamil. ( Jolly, SR; Keaton, N; Movahed, A; Reeves, WC; Rose, GC, 1991)
"25 mm) during experimental tetanus, potassium chloride contracture (KCl), hypoxic contracture (H) as well as joint glucose and oxygen deficiency contracture (HG) in left ventricular papillary muscles of rat and right ventricular papillary muscles of cat myocardium."3.66Force generation in experimental tetanus, KCl contracture, and oxygen and glucose deficiency contracture in mammalian myocardium. ( Holubarsch, C, 1983)
"In an experimental model of hemorrhagic shock, TMZ, ALO, and HTK solution attenuated cell damage in multiple parenchyma and increased antioxidant defenses."1.72Bretschneider Solution and Two Antianginal Drugs Protect Peripheral Tissue in an Animal Model of Hemorrhagic Shock. ( Ambrosio, G; Azzato, F; Cao, G; Milei, J; Moriondo, M; Muller, A; Ortiz Fragola, JP; Sangiorgio, M; Tumarkin, M, 2022)
"To define this we used a murine cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) model or sham procedure on male mice."1.56The acute kidney injury to chronic kidney disease transition in a mouse model of acute cardiorenal syndrome emphasizes the role of inflammation. ( Coe, I; Eiwaz, MB; Ferdaus, MZ; Hutchens, MP; Matsushita, K; McClellan, N; McCormick, JA; Sakai, LY; Saritas, T; Zhu, W, 2020)
"Cardiac arrest was induced in female large white pigs by intravenous injection of potassium chloride."1.46An Oxygenated and Transportable Machine Perfusion System Fully Rescues Liver Grafts Exposed to Lethal Ischemic Damage in a Pig Model of DCD Liver Transplantation. ( Azoulay, D; Ben Mosbah, I; Calderaro, J; Cohen, JL; Compagnon, P; Corlu, A; Disabato, M; Feray, C; Hentati, H; Levesque, E, 2017)
"The random nature of seizures poses difficult challenges for epilepsy research."1.46Control of in vivo ictogenesis via endogenous synaptic pathways. ( Chen, W; Gliske, S; Luna-Munguia, H; Stacey, WC; Starski, P, 2017)
"The treatment with agmatine appeared to be significantly effective in reducing the MDA content and MPO activity besides restoring the content of GSH."1.46Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats. ( Araslı, M; Barut, F; Ozacmak, HS; Ozacmak, VH; Turan, I, 2017)
"Lactic acidosis was fully corrected and survival increased in group PR (50."1.43Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs. ( Bai, XD; Guo, SJ; Hu, S; Hu, XH; Li, ZY; Liu, R; Wang, SM; Zhou, FQ, 2016)
"Hypoxic lactic acidosis was fully corrected in group PORS in 4 h, whereas it worsened in group BORS, and the 24-h survival rate was twice higher in group PORS than in group BORS (45."1.42Pyruvate oral rehydration solution improved visceral function and survival in shock rats. ( He, ZJ; Hu, S; Lin, HY; Luo, HM; Sheng, ZY; Xie, ZY; Yu, W; Zhou, FQ, 2015)
"Cardiac arrest was induced either with HTK (n = 10), HTK-N (n = 10) or HTK-N + S-NO-HSA (n = 10)."1.42The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats. ( Aumayr, K; Dzilic, E; Gasser, H; Hallström, S; Kerjaschki, D; Kreibich, M; Pelzmann, B; Podesser, BK; Trescher, K, 2015)
"Sepsis was induced in rabbits by intravenous injection of lipopolysaccharide."1.42Roles of Toll-Like Receptor 4, IκB Kinase, and the Proteasome in the Intestinal Alterations Caused by Sepsis. ( Arruebo, MP; Gonzalo, S; Grasa, L; Martínez de Salinas, F; Murillo, MD; Plaza, MÁ; Valero, MS; Vergara, C, 2015)
"In a pig model of untreated VF cardiac arrest for 14 minutes, resuscitation with potassium/lidocaine-induced cardiac standstill during conventional CPR tended to reduce myocardial injury and decreased the severity of postresuscitation myocardial dysfunction significantly."1.40Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation. ( Heo, T; Hun Jung, Y; Il Min, Y; Jeong, IS; Joon Lee, S; Kook Lee, B; Lim, V; Woon Jeung, K; Youn Lee, H, 2014)
"Thus allodynia appears to result from a switch in modality specificity within normally nociceptive-specific spinal relay neurons rather than a change in gain within a multimodal ascending tract."1.40Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model. ( Côté, SL; De Koninck, Y; Lavertu, G, 2014)
"In a pig model of untreated VF cardiac arrest for 14 min, resuscitation with potassium-induced cardiac standstill during conventional CPR was found to be feasible."1.39Potassium induced cardiac standstill during conventional cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation cardiac arrest: a feasibility study. ( Heo, T; Jeung, KW; Jung, YH; Lee, BK; Lee, GS; Lee, HY; Lee, SM; Min, YI, 2013)
" Based on these observations we propose that increased CCL5 bioavailability could have a role in determining the abovedescribed impaired presynaptic impairments in both CNS regions."1.39CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice. ( Casazza, S; Di Prisco, S; Merega, E; Milanese, M; Pistoia, V; Pittaluga, A; Raffaghello, L; Summa, M; Uccelli, A, 2013)
"In all livers, parameters of reperfusion injury remained unaffected by EPO."1.38Erythropoietin as additive of HTK preservation solution in cold ischemia/reperfusion injury of steatotic livers. ( Abshagen, K; Eipel, C; Hübschmann, U; Menger, MD; Vollmar, B; Wagner, KF, 2012)
"Controlled hemorrhagic shock (40% of the total blood volume was removed) was induced in 18 animals, which were then treated with normal saline (0."1.37Impact of Plasma-Lyte pH 7.4 on acid-base status and hemodynamics in a model of controlled hemorrhagic shock. ( Bugano, DD; Noritomi, DT; Pereira, AJ; Rehder, PS; Silva, E, 2011)
"After laser treatment, intraocular pressure (IOP) was elevated 1."1.36Altered calcium signaling in an experimental model of glaucoma. ( Akerman, KE; Kaarniranta, K; Kalesnykas, G; Larsson, KP; Niittykoski, M; Uusitalo, H, 2010)
"Hypertension was induced by biweekly subcutaneous injections of 50mg/kg DOCA plus 1% NaCl in drinking water."1.36Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in rats. ( Chen, YY; Du, JR; He, Y; Ji, W; Li, DS; Qiao, KY; Yu, CX; Yu, DK; Zhao, CY, 2010)
"Reperfusion injury induced by cardiac arrest and resuscitation leads to secondary challenges to the brainstem."1.35The loss of hypoxic ventilatory responses following resuscitation after cardiac arrest in rats is associated with failure of long-term survival. ( LaManna, JC; Xu, K, 2009)
"(4) Reperfusion injury was analyzed in the isolated perfused liver by enzyme release and bile production."1.35Attenuated cold storage injury of rat livers using a modified HTK solution. ( Bahde, R; de Groot, H; Gemsa, O; Minin, E; Palmes, D; Rauen, U; Spiegel, HU; Stratmann, U, 2008)
"Approximately 40% of patients with type 2 diabetes present with concurrent hypertension at the time of diabetes diagnosis."1.35Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension. ( Behnke, BJ; Delp, MD; Donato, AJ; Laughlin, MH; Lesniewski, LA; Ray, CA; Woodman, CR, 2008)
"The prevalence of migraine is much greater in female than male individuals."1.34Reduced threshold for cortical spreading depression in female mice. ( Arnold, AP; Brennan, KC; Charles, AC; López Valdés, HE; Romero Reyes, M, 2007)
"Perinatal asphyxia was induced by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 16 or 20 min."1.34Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth. ( Bustamante, D; Goiny, M; Herrera-Marschitz, M; Morales, P; Pereyra, JT, 2007)
"Pretreatment with diazoxide significantly reduced the infarct volume from 6."1.33MitoKATP-channel opener protects against neuronal death in rat venous ischemia. ( Alessandri, B; Heimann, A; Kempski, O; Nakagawa, I, 2005)
"Iloprost was the most potent agonist to induce cAMP accumulation and SP release among prostanoid agonists evaluated in this study and its effect is mediated by IP receptor."1.33Functional role of prostacyclin receptor in rat dorsal root ganglion neurons. ( Gupta, J; Hayashi, F; Hayashi, M; Iino, T; Nakae, K; Yamamoto, N; Yoshikawa, S, 2005)
"Hypothyroidism was induced in rats by the administration of 6-n-propyl-2-thiouracil in drinking water (final concentration of 0."1.33Decreased vascular reactivity to alpha1 adrenergic stimulation in the presence of hypothyroid state: a part of an adaptive response? ( Asimacopoulos, P; Cokkinos, DV; Karageorgiou, H; Katramadou, M; Kostopanagiotou, G; Mourouzis, C; Mourouzis, I; Pantos, C; Saranteas, T; Tesseromatis, C, 2006)
" These results present a novel interpretation of synergistic inhibition of certain epileptic discharges using vigabatrin and another drug, and that for successful synergistic treatment of epilepsies carefully designed timed dosage regimens are essential."1.33Antiepileptic action induced by a combination of vigabatrin and tiagabine. ( Fueta, Y; Kunugita, N; Schwarz, W, 2005)
"In the kainate model of continuous seizures in rat, we find a loss of Kv2."1.32Regulation of ion channel localization and phosphorylation by neuronal activity. ( Anderson, AE; Leung, V; Misonou, H; Misonou, K; Mohapatra, DP; Park, EW; Trimmer, JS; Zhen, D, 2004)
"A model of potassium-induced cardiac arrest was established in C57BL/6 mice."1.32Intra-arrest cooling improves outcomes in a murine cardiac arrest model. ( Abella, BS; Alvarado, J; Becker, LB; Hamann, K; Vanden Hoek, TL; Zhao, D, 2004)
"Quercetin and verapamil treatments reduced the endothelium-independent hyper-reactivity to KCl observed in the aorta of DOCA-salt-hypertensive rats, but only quercetin increased the contractile responses to angiotensin II, improved endothelial dysfunction and restored basal aortic Cu/Zn SOD expression, altered in DOCA-salt-treated rats."1.32Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil. ( Duarte, J; Galisteo, M; García-Saura, MF; Jiménez, R; Vargas, F; Villar, IC; Wangensteen, R; Zarzuelo, A, 2004)
"Chronic relapsing/remitting experimental autoimmune encephalomyelitis (EAE) can be induced in 8-week-old female SJL/J(H-2) mice via inoculation with the p139-151 peptide of myelin proteolipid protein (PLP), Mycobacterium tuberculosis (MT), complete Freund's adjuvant (CFA), and Bordatella pertussis."1.32An electrophysiological model of spinal transmission deficits in mouse experimental autoimmune encephalomyelitis. ( Black, MD; Hanak, SE; McMonagle-Strucko, K; Pulicicchio, C; Reilly, EM; Wettstein, JG; Wotanis, J; Zhu, B, 2004)
"Our results suggest that bladder outlet obstruction produces a muscle cell that develops higher levels of force but with greatly reduced cross bridge cycling rates."1.32Effect of partial outlet obstruction on rabbit urinary bladder smooth muscle function. ( Moreland, RS; Stanton, MC; Stein, R; Su, X; Zderic, S, 2003)
" The dose-response curve for NE (0."1.31Lead-cadmium interaction effect on the responsiveness of rat mesenteric vessels to norepinephrine and angiotensin II. ( Andrzejak, R; Skoczyńska, A; Wróbel, J, 2001)
"Cerebral vasospasm following subarachnoid hemorrhage (SAH) is one of the leading factors that deteriorate the clinical outcome after aneurysmal surgery."1.29Percutaneous transluminal angioplasty in a canine model of cerebral vasospasm: angiographic, histologic, and pharmacologic evaluation. ( Fujii, Y; Takahashi, A; Yoshimoto, T, 1995)
"Portal hypertension was induced by partial portal vein ligation (PVL)."1.29Vascular hyporesponsiveness in aorta from portal hypertensive rats: possible sites of involvement. ( Chang, SP; Hong, CY; Huang, YT; Lin, HC; Wang, GF; Yang, MC, 1996)
" Dose-response curves to acetylcholine (0."1.29Modification of aortic contractility in the cardiomyopathic hamster. ( Dumont, EC; Lambert, C; Lamontagne, D, 1996)
"Indomethacin treatment did not affect endothelium-dependent relaxation in the control solution but partially restored the response to ACh in elevated glucose."1.29Magnesium modulates endothelial dysfunction produced by elevated glucose incubation. ( Duhault, J; Félétou, M; Rasetti, C, 1994)
"The histamine output was markedly reduced by intraperitoneal injection of alpha-fluoromethylhistidine (100 mg/kg), an irreversible inhibitor of histidine decarboxylase, or (R)-alpha-methylhistamine (5 mg/kg), a potent and specific H3-receptor agonist."1.28Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion. ( Adachi, N; Itoh, Y; Oishi, R; Saeki, K, 1992)

Research

Studies (245)

TimeframeStudies, this research(%)All Research%
pre-199027 (11.02)18.7374
1990's30 (12.24)18.2507
2000's84 (34.29)29.6817
2010's95 (38.78)24.3611
2020's9 (3.67)2.80

Authors

AuthorsStudies
Yang, S1
Liu, Y1
Huang, S1
Jin, F1
Qi, F1
DeSpain, K1
Rosenfeld, CR1
Huebinger, R1
Wang, X1
Jay, JW1
Radhakrishnan, RS1
Wolf, SE1
Song, J1
Ortiz Fragola, JP1
Cao, G1
Tumarkin, M1
Moriondo, M1
Muller, A1
Sangiorgio, M1
Azzato, F1
Ambrosio, G1
Milei, J1
Kamakura, T1
Kitahara, T1
Kondo, M1
Horii, A1
Hanada, Y1
Takimoto, Y1
Ishida, Y1
Nakamura, Y1
Imai, T1
Inohara, H1
Shimada, S1
Matsushita, K1
Saritas, T1
Eiwaz, MB1
McClellan, N1
Coe, I1
Zhu, W1
Ferdaus, MZ1
Sakai, LY1
McCormick, JA1
Hutchens, MP1
Yamaguchi, M1
Ishikawa, M1
Aono, Y1
Saigusa, T1
Chen, Z1
Kebschull, L1
Föll, DA1
Rauen, U3
Hansen, U1
Heitplatz, B1
Hessler, M1
Senninger, N1
Vogel, T1
Mohr, A1
Becker, F1
Oğuz, S1
Aşgün, HF1
Büyük, B1
Rutledge, CA1
Chiba, T1
Redding, K1
Dezfulian, C1
Sims-Lucas, S1
Kaufman, BA1
Monai, H1
Koketsu, S1
Shinohara, Y1
Ueki, T1
Kusk, P1
Hauglund, NL1
Samson, AJ1
Nedergaard, M1
Hirase, H1
Compagnon, P1
Levesque, E1
Hentati, H1
Disabato, M1
Calderaro, J1
Feray, C1
Corlu, A1
Cohen, JL1
Ben Mosbah, I1
Azoulay, D1
Luna-Munguia, H1
Starski, P1
Chen, W2
Gliske, S1
Stacey, WC1
Glendinning, JI1
Tang, J1
Morales Allende, AP1
Bryant, BP1
Youngentob, L1
Youngentob, SL1
Özer, N1
Bülbüloğlu, E1
Yormaz, S1
Ece, İ1
Turan, I1
Ozacmak, HS1
Ozacmak, VH1
Barut, F1
Araslı, M1
Liu, Q1
Luo, D1
Yang, T1
Liao, B1
Li, H1
Wang, KJ1
Moraga, FA1
Miranda, G1
López, V1
Vallejos, C1
Silva, D1
Lautenschläger, I1
Pless-Petig, G1
Middel, P1
de Groot, H2
Stojanovic, T1
Wang, D1
Zhang, X2
Qu, D1
Han, J1
Meng, F1
Xu, M1
Zheng, Q1
Sugimoto, K1
Nomura, S1
Shirao, S1
Inoue, T1
Ishihara, H1
Kawano, R1
Kawano, A1
Oka, F1
Suehiro, E1
Sadahiro, H1
Shinoyama, M1
Oku, T1
Maruta, Y1
Hirayama, Y1
Hiyoshi, K1
Kiyohira, M1
Yoneda, H1
Okazaki, K1
Dreier, JP1
Suzuki, M1
Wang, H3
Jing, R1
Trexler, C1
Li, Y1
Tang, H1
Pan, Z1
Zhu, S1
Zhao, B1
Fang, X1
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Song, X1
Kunz, WS1
Goussakov, IV1
Beck, H1
Elger, CE1
Mitani, Y1
Maruyama, J1
Maruyama, K1
Sakurai, M1
Uesaka, T1
Chiba, Y1
Ihaya, A1
Nara, M1
Niwa, H1
Muraoka, R1
Otsuka, H1
Ueda, K1
Jung, O1
Jung, W1
Malinski, T1
Wiemer, G1
Schoelkens, BA1
Linz, W1
Jolma, P1
Kalliovalkama, J1
Tolvanen, JP1
Kööbi, P1
Kähönen, M1
Hutri-Kähönen, N1
Wu, X1
Pörsti, I1
Ohkohchi, N1
Oikawa, K1
Sasaki, K1
Satomi, S1
Ruiz-Marcos, FM1
Ortíz, MC1
Fortepiani, LA1
Nadal, FJ1
Atucha, NM1
García-Estañ, J1
Keeling, IM1
Obermayr, RP1
Schneider, B1
Spieckermann, PG1
Skoczyńska, A1
Wróbel, J1
Andrzejak, R1
Ma, W1
Pancrazio, JJ1
Andreadis, JD1
Shaffer, KM1
Stenger, DA1
Li, BS1
Zhang, L1
Barker, JL1
Maric, D1
Amano, H1
Amano, T1
Matsubayashi, H1
Ishihara, K1
Serikawa, T1
Sasa, M1
Zhang, ZD1
Yamini, B1
Komuro, T1
Ono, S1
Johns, L1
Marton, LS1
Weir, B1
Macdonald, RL1
Shelkovnikov, SA1
Gonick, HC1
Flores, CM1
Leong, AS1
Dussor, GO1
Harding-Rose, C1
Hargreaves, KM1
Kilo, S1
Slaght, SJ1
Leresche, N1
Deniau, JM1
Crunelli, V1
Charpier, S1
Ellis, RJ1
Pryor, W1
Ebert, A1
Opie, LH1
Bruyneel, K1
Owen, P1
Okumura, F1
Crocker, BD1
Denborough, MA1
Hansen, TR1
Bohr, DF1
Zipes, DP1
Fischer, J1
King, RM1
Jolly, WW1
Overbeck, HW1
Clark, DW1
Crocker, JF1
Stewart, AG1
Sparling, JM1
Bruneau, ME1
Adachi, N1
Itoh, Y1
Oishi, R1
Saeki, K1
Marcek, JM1
Seaman, WJ1
Weaver, RJ1
Jolly, SR1
Keaton, N1
Movahed, A1
Rose, GC1
Reeves, WC1
Shvilkin, AV1
Levitskiĭ, DO1
Serebriakova, LI1
Tskitishvili, OV1
Sadretdinov, SM1
Borok, Z1
Schneider, SM1
Fraley, DS1
Adler, S1
Bourgoignie, JJ1
Gavellas, G1
Van Putten, V1
Berl, T1
Kaufman, T1
Eichenlaub, EH1
Angel, MF1
Levin, M1
Futrell, JW1
Grimm, RJ1
Frazee, JG1
Ozbay, S1
Paukov, VS1
Ovsiannikov, AM1
Frolov, VA1
Gorodinskaia, VIa1
Schneiderman, B1
Isaacson, RL1
Van Hartesveldt, C1
Hofmann, WW1
Ruprecht, EO1
Hübner, G1
Appelgren, KL1
Lewis, DH1
Groh, J1
Zdánský, P1
Brátová, M1
Truhlárová, J1
Synková, J1
Bajusz, E1
Homburger, F1
Baker, JR1
Bogdonoff, P1
Pokk, LR1
Levinson, RS1
McIlduff, JB1
Selye, H1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Extracoporeal Shock Wave Therapy (ESWT) for the Treatment of Detrusor Underactivity/ Underactive Bladder (DU/UAB) - a Single Center, Randomized, Double-blind, Placebo-controlled, Prospective Study[NCT04161183]11 participants (Actual)Interventional2019-10-15Completed
Can Acupoint Low Intensity Shockwave Therapy Improve Bladder Voiding Efficiency: A Pilot Study.[NCT06020963]100 participants (Anticipated)Interventional2023-08-11Recruiting
Sodium-Glucose Cotransporter-2 Inhibitors: A Potential Novel Treatment for Epilepsy[NCT05512130]Early Phase 118 participants (Anticipated)Interventional2022-08-17Recruiting
Custodiol-HTK Solution as a Cardioplegic Agent- A Prospective Non-Inferiority Randomized Clinical Trial[NCT01681095]Phase 2110 participants (Actual)Interventional2012-08-31Completed
Major Cations Targeted Fluid Therapy In Renal Transplantation.[NCT03846869]50 participants (Anticipated)Interventional2019-02-01Active, not recruiting
Comparison of Honey and Povidone-iodine in Wound Healing on Acute Laceration Wounds: A Randomized Controlled Trial Study[NCT03641053]Phase 335 participants (Actual)Interventional2018-01-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

All Cause Mortality

Number of participants with all-cause mortality AS reported in the Society of Thoracic Surgeons (STS) database after 30 days postoperative (NCT01681095)
Timeframe: 30 days post procedure

Interventionparticipants (Number)
Cardioplegia: Custodiol HTK Solution0
Cold Blood Cardioplegia0

Biochemical Marker - Creatine Kinase MB Isoenzyme (CK-MB)

CK-MB measured 24 hours post-operatively (NCT01681095)
Timeframe: 24 hours post procedure

Interventionng/mL (Mean)
Cardioplegia: Custodiol HTK Solution20
Cold Blood Cardioplegia24

Biochemical Marker - Creatine Kinase MB Isoenzyme (CK-MB)

CK-MB measured 48 hours post-operatively (NCT01681095)
Timeframe: 48 hours post procedure

Interventionng/mL (Mean)
Cardioplegia: Custodiol HTK Solution6.0
Cold Blood Cardioplegia7.8

Biochemical Marker - Creatine Kinase MB Isoenzyme (CK-MB)

CK-MB measured pre-operatively (NCT01681095)
Timeframe: pre-operative

Interventionng/mL (Mean)
Cardioplegia: Custodiol HTK Solution1.9
Cold Blood Cardioplegia2.6

Cardiac Dysrhythmias

Number of participants with new or worsening of cardiac dysrhythmias (NCT01681095)
Timeframe: up to 36 hrs post surgery

Interventionparticipants (Number)
Cardioplegia: Custodiol HTK Solution24
Cold Blood Cardioplegia30

Cardiac Marker - Troponin-I

Troponin-I measured 24 hours post-operative (NCT01681095)
Timeframe: 24 hours post procedure

Interventionng/mL (Mean)
Cardioplegia: Custodiol HTK Solution5.7
Cold Blood Cardioplegia7.8

Cardiac Marker - Troponin-I

Troponin-I measured 48 hours post-operative (NCT01681095)
Timeframe: 48 hours post procedure

Interventionng/mL (Mean)
Cardioplegia: Custodiol HTK Solution3.0
Cold Blood Cardioplegia4.8

Cardiac Marker - Troponin-I

Troponin-I measured pre-operatively (NCT01681095)
Timeframe: pre-operatively

Interventionng/mL (Mean)
Cardioplegia: Custodiol HTK Solution.03
Cold Blood Cardioplegia.03

Cardiovascular Mortality

Number of participants with cardiovascular-related mortality AS reported in the Society of Thoracic Surgeons (STS) database after 30 days postoperative (NCT01681095)
Timeframe: 30 days post procedure

Interventionparticipants (Number)
Cardioplegia: Custodiol HTK Solution0
Cold Blood Cardioplegia0

Change in Creatine Phosphokinase-MB Isoenzyme (CK-MB)

Creatine phosphokinase MB isoenzyme (CK-MB) difference from baseline 7 hours post surgery (NCT01681095)
Timeframe: Baseline and 7 hours post surgery

Interventionng/mL (Median)
Cardioplegia: Custodiol HTK Solution18.8
Cold Blood Cardioplegia22.2

Change in Troponin I

Troponin I values, difference from baseline 7 hours post surgery (NCT01681095)
Timeframe: Baseline and 7 hours post surgery

Interventionng/mL (Median)
Cardioplegia: Custodiol HTK Solution9.65
Cold Blood Cardioplegia10.15

Changes in Left Ventricular (LV) Ejection Fraction (EF) by Transthoracic Echocardiogram (TTE)

LV ejection fraction by TTE, difference from baseline at 24 hours post surgery (NCT01681095)
Timeframe: Baseline and 24 hours post surgery

Intervention% LV volume (Mean)
Cardioplegia: Custodiol HTK Solution-0.06
Cold Blood Cardioplegia1.9

Duration of Vasopressor / Inotropic Agent

Total time in minutes on any vasopressor or inotropic agent, including norepinephrine, epinephrine, vasopressin, milrinone, dobutamine, dopamine and/or neo-synephrine (NCT01681095)
Timeframe: up to 36 hours post procedure

Interventionminutes (Median)
Cardioplegia: Custodiol HTK Solution340
Cold Blood Cardioplegia582

Intensive Care Unit (ICU) Length of Stay

Duration of stay in ICU, from ICU admission to ICU discharge (NCT01681095)
Timeframe: up to 100 days after admission

Interventiondays (Median)
Cardioplegia: Custodiol HTK Solution3
Cold Blood Cardioplegia3

Myocardial Infarction

Number or participants fulfilling at least two of the following 3 criteria: (1) CK-MB of 100 ug/L or more and/or troponin-I of 3.0 ug/L or more, (2) appearance of new postoperative Q waves on the EKG of more than 0.03 seconds, and (3) a new hypokinetic or akinetic area in the left or right ventricle by echocardiography. (NCT01681095)
Timeframe: up to 36 hours post procedure

Interventionparticipants (Number)
Cardioplegia: Custodiol HTK Solution0
Cold Blood Cardioplegia0

Postoperative Inotropic Infusion >20 Minutes

Number of patients receiving vasopressor or inotropic infusion for greater than 20 minutes in the operating room, including norepinephrine, epinephrine, vasopressin, milrinone, dobutamine, dopamine and/or neo-synephrine. (NCT01681095)
Timeframe: during operative procedure

Interventionparticipants (Number)
Cardioplegia: Custodiol HTK Solution47
Cold Blood Cardioplegia43

Time on Mechanically Assisted Ventilation

time in hours from intubation to extubation, with intervening transport to the cardiac critical care unit. (NCT01681095)
Timeframe: up to 36 hours post procedure

Interventionhours (Median)
Cardioplegia: Custodiol HTK Solution10.5
Cold Blood Cardioplegia11.4

Reviews

2 reviews available for potassium chloride and Disease Models, Animal

ArticleYear
[Combined effect of beta-adrenoblockaders with other pharmacologic agents (review of the literature)].
    Vrachebnoe delo, 1971, Volume: 7

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, Inhalation; Angina Pectoris;

1971
Electron microscopic investigation of cardioplegia. Electron microscopy of various forms of cardiac arrest in correlation with myocardial function.
    Methods and achievements in experimental pathology, 1971, Volume: 5

    Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Citrates; Coronary Disease; Disease Models, Animal; D

1971

Trials

1 trial available for potassium chloride and Disease Models, Animal

ArticleYear
Cilostazol decreases duration of spreading depolarization and spreading ischemia after aneurysmal subarachnoid hemorrhage.
    Annals of neurology, 2018, Volume: 84, Issue:6

    Topics: Aged; Animals; Brain Ischemia; Cerebrovascular Circulation; Cilostazol; Cortical Spreading Depressio

2018

Other Studies

242 other studies available for potassium chloride and Disease Models, Animal

ArticleYear
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas.
    BMC anesthesiology, 2021, 09-01, Volume: 21, Issue:1

    Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental;

2021
Carotid smooth muscle contractility changes after severe burn.
    Scientific reports, 2021, 09-10, Volume: 11, Issue:1

    Topics: Animals; Biomarkers; Burns; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Dr

2021
Bretschneider Solution and Two Antianginal Drugs Protect Peripheral Tissue in an Animal Model of Hemorrhagic Shock.
    Journal of cardiovascular pharmacology, 2022, 06-01, Volume: 79, Issue:6

    Topics: Allopurinol; Animals; Cardiovascular Agents; Disease Models, Animal; Glucose; Glutathione; Insulin;

2022
Rat Model of Ménière's Attack: Intratympanic Injection of Potassium Chloride Produces Direction-Changing Spontaneous Nystagmus and Hearing Fluctuations.
    Audiology & neuro-otology, 2019, Volume: 24, Issue:5

    Topics: Animals; Disease Models, Animal; Hearing; Injection, Intratympanic; Male; Meniere Disease; Nystagmus

2019
The acute kidney injury to chronic kidney disease transition in a mouse model of acute cardiorenal syndrome emphasizes the role of inflammation.
    Kidney international, 2020, Volume: 97, Issue:1

    Topics: Acute Kidney Injury; Animals; Cardio-Renal Syndrome; Cardiopulmonary Resuscitation; Disease Models,

2020
OX
    Neuropsychopharmacology reports, 2020, Volume: 40, Issue:1

    Topics: Animals; Behavior, Animal; Calcium; Chronic Pain; Disease Models, Animal; Ganglia, Spinal; Hyperalge

2020
A novel histidine-tryptophan-ketoglutarate formulation ameliorates intestinal injury in a cold storage and ex vivo warm oxygenated reperfusion model in rats.
    Bioscience reports, 2020, 05-29, Volume: 40, Issue:5

    Topics: Animals; Cold Ischemia; Disease Models, Animal; Glucose; Humans; Intestinal Mucosa; Intestine, Small

2020
Effectiveness of Brain Protection With Histidine-Tryptophan-Ketoglutarate Solutions.
    The heart surgery forum, 2020, Jul-22, Volume: 23, Issue:4

    Topics: Animals; Biopsy; Brain; Brain Ischemia; Cardioplegic Solutions; Disease Models, Animal; Glucose; Mal

2020
A novel ultrasound-guided mouse model of sudden cardiac arrest.
    PloS one, 2020, Volume: 15, Issue:12

    Topics: Animals; Death, Sudden, Cardiac; Disease Models, Animal; Female; Heart Arrest; Heart Ventricles; Kid

2020
Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.
    Scientific reports, 2021, 04-14, Volume: 11, Issue:1

    Topics: Adrenergic Antagonists; Animals; Calcium; Cortical Spreading Depression; Disease Models, Animal; Fem

2021
An Oxygenated and Transportable Machine Perfusion System Fully Rescues Liver Grafts Exposed to Lethal Ischemic Damage in a Pig Model of DCD Liver Transplantation.
    Transplantation, 2017, Volume: 101, Issue:7

    Topics: Allografts; Animals; Biomarkers; Disease Models, Animal; Energy Metabolism; Equipment Design; Female

2017
Control of in vivo ictogenesis via endogenous synaptic pathways.
    Scientific reports, 2017, 05-02, Volume: 7, Issue:1

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Humans; Midline Thalamic Nucl

2017
Fetal alcohol exposure reduces responsiveness of taste nerves and trigeminal chemosensory neurons to ethanol and its flavor components.
    Journal of neurophysiology, 2017, 08-01, Volume: 118, Issue:2

    Topics: Animals; Capsaicin; Central Nervous System Depressants; Chorda Tympani Nerve; Dietary Sucrose; Disea

2017
Evaluation of silybum marinaum efficacy on University of Wisconsin and histidine-tryptophan-ketoglutarate solutions latter the damage of the perfused liver.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:6

    Topics: Adenosine; Allopurinol; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Model

2017
Agmatine attenuates intestinal ischemia and reperfusion injury by reducing oxidative stress and inflammatory reaction in rats.
    Life sciences, 2017, Nov-15, Volume: 189

    Topics: Agmatine; Animals; Carbachol; Disease Models, Animal; Inflammation; Intestine, Small; Male; Malondia

2017
Protective Effects of Antimuscarinics on the Bladder Remodeling After Bladder Outlet Obstruction.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 44, Issue:3

    Topics: Animals; Benzofurans; Cell Line; Cell Proliferation; Collagen; Cytokines; Disease Models, Animal; Fe

2017
Chronic Intermittent Hypobaric Hypoxia (4600 M) Attenuates Pulmonary Vasodilation Induced by Acetylcholine or Sodium Nitroprusside.
    High altitude medicine & biology, 2018, Volume: 19, Issue:2

    Topics: Acetylcholine; Altitude; Altitude Sickness; Animals; Blood Pressure; Body Weight; Chronic Disease; D

2018
Cold Storage Injury to Rat Small-bowel Transplants-Beneficial Effect of a Modified HTK Solution.
    Transplantation, 2018, Volume: 102, Issue:10

    Topics: Alanine; Animals; Cell Hypoxia; Cold Ischemia; Disease Models, Animal; Glucose; Glycine; Humans; Int

2018
Astragalin and dihydromyricetin as adjuncts to histidine‑tryptophan‑ketoglutarate cardioplegia enhances protection during cardioplegic arrest.
    Molecular medicine reports, 2018, Volume: 18, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Cardioplegic Solutions; Cardiotonic Agents; Cytokines; Disease Model

2018
Deletion of IP
    Journal of gastroenterology, 2019, Volume: 54, Issue:5

    Topics: Animals; Carbachol; Cholinergic Agonists; Colon; Disease Models, Animal; Gastrointestinal Transit; I

2019
Propranolol prevents cerebral blood flow changes and pain-related behaviors in migraine model mice.
    Biochemical and biophysical research communications, 2019, 01-08, Volume: 508, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Di

2019
Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368.
    BMC anesthesiology, 2019, 01-08, Volume: 19, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Gap Junc

2019
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
    International urology and nephrology, 2019, Volume: 51, Issue:4

    Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol

2019
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
    International urology and nephrology, 2019, Volume: 51, Issue:4

    Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol

2019
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
    International urology and nephrology, 2019, Volume: 51, Issue:4

    Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol

2019
Long-term functional change of cryoinjury-induced detrusor underactivity and effects of extracorporeal shock wave therapy in a rat model.
    International urology and nephrology, 2019, Volume: 51, Issue:4

    Topics: Actins; Animals; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Carbachol; Chol

2019
The Novel N,N-bis-2-Hydroxyethyl-2-Aminoethanesulfonic Acid-Gluconate-Polyethylene Glycol-Hypothermic Machine Perfusion Solution Improves Static Cold Storage and Reduces Ischemia/Reperfusion Injury in Rat Liver Transplant.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2019, Volume: 25, Issue:9

    Topics: Alkanesulfonic Acids; Allografts; Animals; Cold Ischemia; Disease Models, Animal; Gluconates; Glucos

2019
Long-term Effects of Hypothermic Ex Situ Perfusion on Skeletal Muscle Metabolism, Structure, and Force Generation After Transplantation.
    Transplantation, 2019, Volume: 103, Issue:10

    Topics: Amputation, Traumatic; Animals; Cold Ischemia; Disease Models, Animal; Glucose; Hindlimb; Humans; Ma

2019
CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice.
    Neuropharmacology, 2013, Volume: 75

    Topics: Age Factors; Animals; Animals, Newborn; Central Nervous System; Chemokine CCL5; Colforsin; D-Asparti

2013
Isoflurane suppresses cortical spreading depolarizations compared to propofol--implications for sedation of neurocritical care patients.
    Experimental neurology, 2014, Volume: 252

    Topics: Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Disease Models, Animal; Dose-Re

2014
Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 3

    Topics: Animals; Disease Models, Animal; Hyperalgesia; Ion Transport; Male; Microelectrodes; Neurons; Nocice

2014
Autocrine C-peptide mechanism underlying INS1 beta cell adaptation to oxidative stress.
    Diabetes/metabolism research and reviews, 2014, Volume: 30, Issue:7

    Topics: Adaptation, Physiological; Animals; Apoptosis; Autocrine Communication; C-Peptide; Cell Line, Tumor;

2014
Effects of chronic treatment with cilostazol, a phosphodiesterase 3 inhibitor, on female rat bladder in a partial bladder outlet obstruction model.
    Urology, 2014, Volume: 83, Issue:3

    Topics: Animals; Carbachol; Cilostazol; Disease Models, Animal; Electric Stimulation; Female; Muscle Contrac

2014
In vitro smooth muscle contractility before and after relief of experimental obstruction in the rat: application to the surgical management of ileal dilatation.
    Journal of pediatric surgery, 2014, Volume: 49, Issue:3

    Topics: Acetylcholine; Animals; Dilatation, Pathologic; Disease Models, Animal; Electric Stimulation; Gastro

2014
Serotonin depletion can enhance the cerebrovascular responses induced by cortical spreading depression via the nitric oxide pathway.
    The International journal of neuroscience, 2015, Volume: 125, Issue:2

    Topics: Analysis of Variance; Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Disease M

2015
Aberrant glutamate signaling in the prefrontal cortex and striatum of the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder.
    Psychopharmacology, 2014, Volume: 231, Issue:15

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Agents; Corpus Striat

2014
Effects of potassium/lidocaine-induced cardiac standstill during cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:4

    Topics: Animals; Biomarkers; Cardioplegic Solutions; Cardiopulmonary Resuscitation; Disease Models, Animal;

2014
Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy.
    Experimental neurology, 2014, Volume: 257

    Topics: Animals; Calcium; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocam

2014
Androgens are bronchoactive drugs that act by relaxing airway smooth muscle and preventing bronchospasm.
    The Journal of endocrinology, 2014, Volume: 222, Issue:1

    Topics: Androgens; Animals; Bronchial Spasm; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator

2014
Experience salience gates endocannabinoid signaling at hypothalamic synapses.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Apr-30, Volume: 34, Issue:18

    Topics: Analgesics; Animals; Animals, Newborn; Benzoxazines; Disease Models, Animal; Dose-Response Relations

2014
Interactions of PPAR α and GLUT4 in DOCA/salt-induced renal injury in mice.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2013, Dec-20, Volume: 28, Issue:2

    Topics: Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Fenofibrate; Glucose Transporter Type

2013
Presence and release of ATP from the retina in an Alzheimer's disease model.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 43, Issue:1

    Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Disease Models, Animal; Extracellular Space; Fem

2015
Pyruvate oral rehydration solution improved visceral function and survival in shock rats.
    The Journal of surgical research, 2015, Volume: 193, Issue:1

    Topics: Acidosis, Lactic; Animals; Bicarbonates; Disease Models, Animal; Fluid Therapy; Glucose; Lipid Perox

2015
Neuronal hyperactivity recruits microglial processes via neuronal NMDA receptors and microglial P2Y12 receptors after status epilepticus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-06, Volume: 34, Issue:32

    Topics: Animals; Cell Surface Extensions; CX3C Chemokine Receptor 1; Disease Models, Animal; Dose-Response R

2014
Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease.
    Neurobiology of disease, 2014, Volume: 71

    Topics: Action Potentials; Adenine; Adenosine A1 Receptor Antagonists; Animals; Cerebral Cortex; Corpus Stri

2014
Roles of Toll-Like Receptor 4, IκB Kinase, and the Proteasome in the Intestinal Alterations Caused by Sepsis.
    Digestive diseases and sciences, 2015, Volume: 60, Issue:5

    Topics: Acetylcholine; Animals; Cell-Penetrating Peptides; Cytokines; Dinoprostone; Disease Models, Animal;

2015
Altered neurotransmission prior to cognitive decline in AβPP/PS1 mice, a model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition

2015
Evidence for orexinergic mechanisms in migraine.
    Neurobiology of disease, 2015, Volume: 74

    Topics: Animals; Azepines; Benzimidazoles; Central Nervous System Agents; Cortical Spreading Depression; Dis

2015
The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats.
    Interactive cardiovascular and thoracic surgery, 2015, Volume: 20, Issue:3

    Topics: Animals; Cardiac Output; Cardioplegic Solutions; Disease Models, Animal; Glucose; Heart Arrest; Hear

2015
Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis.
    Neurobiology of disease, 2015, Volume: 75

    Topics: Aging; Animals; CADASIL; Cell Survival; Cells, Cultured; Cerebral Arteries; Disease Models, Animal;

2015
Effect of Potassium Citrate on Calcium Phosphate Stones in a Model of Hypercalciuria.
    Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:12

    Topics: Animals; Calcium; Calcium Oxalate; Calcium Phosphates; Calcium, Dietary; Citric Acid; Disease Models

2015
Chronic ouabain treatment induces Rho kinase activation.
    Archives of pharmacal research, 2015, Volume: 38, Issue:10

    Topics: Amides; Animals; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; Myosin-Light-Chain P

2015
Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Acetanilides; Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Atropine; Calcium Chloride; Carb

2015
Postmortem computed tomography findings in the thorax - Experimental evaluation.
    Legal medicine (Tokyo, Japan), 2016, Volume: 19

    Topics: Animals; Asphyxia; Autopsy; Disease Models, Animal; Drowning; Female; Forensic Pathology; Hypothermi

2016
Influence of a modified preservation solution in kidney transplantation: A comparative experimental study in a porcine model.
    Asian journal of surgery, 2017, Volume: 40, Issue:2

    Topics: Adenosine; Allopurinol; Animals; Biopsy, Needle; Disease Models, Animal; Female; Glucose; Glutathion

2017
Effects of apelin-13 in mice model of experimental pain and peripheral nociceptive signaling in rat sensory neurons.
    Journal of receptor and signal transduction research, 2016, Volume: 36, Issue:3

    Topics: Animals; Calcium Signaling; Disease Models, Animal; Fluorescence; Ganglia, Spinal; Hot Temperature;

2016
Mild systemic inflammation and moderate hypoxia transiently alter neuronal excitability in mouse somatosensory cortex.
    Neurobiology of disease, 2016, Volume: 88

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; A

2016
Alcohol-triggered signs of migraine: An animal model.
    Somatosensory & motor research, 2016, Volume: 33, Issue:1

    Topics: Alcohols; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Psychological; Disease Mo

2016
Influences of limited resuscitation with plasma or plasma protein solutions on hemostasis and survival of rabbits with noncompressible hemorrhage.
    The journal of trauma and acute care surgery, 2016, Volume: 81, Issue:1

    Topics: Animals; Crystalloid Solutions; Disease Models, Animal; Gluconates; Hemorrhage; Hemostatics; Isotoni

2016
Improvement of surface ECG recording in adult zebrafish reveals that the value of this model exceeds our expectation.
    Scientific reports, 2016, 04-29, Volume: 6

    Topics: Animals; Arrhythmias, Cardiac; Calcium Gluconate; Disease Models, Animal; Electrocardiography; Heart

2016
Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:4

    Topics: Animals; Bicarbonates; Burns; Capillary Permeability; Disease Models, Animal; Dogs; Fluid Therapy; F

2016
Glutamate release and uptake processes are altered in a new mouse model of amyotrophic lateral sclerosis.
    Doklady. Biochemistry and biophysics, 2016, Volume: 468, Issue:1

    Topics: Aging; Amyotrophic Lateral Sclerosis; Animals; Cations, Monovalent; Central Nervous System Agents; C

2016
Pulsed Radiofrequency Attenuates Complete Freund's Adjuvant-Induced Epigenetic Suppression of Potassium Chloride Cotransporter 2 Expression.
    Pain medicine (Malden, Mass.), 2017, 04-01, Volume: 18, Issue:4

    Topics: Animals; Chronic Pain; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic; Freund's Adjuva

2017
The histopathological and pharmacodynamic effects of intradetrusor decorin injected in a rabbit partial bladder outlet obstruction model.
    International urology and nephrology, 2017, Volume: 49, Issue:4

    Topics: Animals; Carbachol; Decorin; Disease Models, Animal; Electric Stimulation; Fibrosis; Injections, Int

2017
Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid.
    Journal of neuroinflammation, 2017, 01-31, Volume: 14, Issue:1

    Topics: Animals; Body Weight; Corpus Striatum; Cytokines; Disease Models, Animal; Dose-Response Relationship

2017
Dual-contrast agent photon-counting computed tomography of the heart: initial experience.
    The international journal of cardiovascular imaging, 2017, Volume: 33, Issue:8

    Topics: Animals; Cicatrix; Contrast Media; Disease Models, Animal; Dogs; Feasibility Studies; Heart; Image I

2017
Effects of taurine on aortic rings isolated from fructose-fed insulin resistance Sprague-Dawley rat are changed.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:6

    Topics: 4-Aminopyridine; Acetylcholine; Administration, Oral; Animals; Aorta; Blood Glucose; Blood Pressure;

2008
Estrogen administration attenuates bladder outlet obstruction induced oxidative stress in the female rabbit.
    Neurourology and urodynamics, 2009, Volume: 28, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Carbachol; Choline O-Acetyltransferase; Cholinergic A

2009
Differential [Ca2+]i signaling of vasoconstriction in mesenteric microvessels of normal and reduced uterine perfusion pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:6

    Topics: Angiotensin II; Animals; Calcium Signaling; Disease Models, Animal; Endothelin-1; Feedback, Physiolo

2008
Involvement of voltage-gated sodium channel Na(v)1.8 in the regulation of the release and synthesis of substance P in adult mouse dorsal root ganglion neurons.
    Journal of pharmacological sciences, 2008, Volume: 108, Issue:2

    Topics: Animals; Capsaicin; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fluor

2008
Effect of protein kinase C and protein kinase A inhibitors on contraction of isolated femoral arteries of SHR and Wistar rats.
    Physiological research, 2009, Volume: 58, Issue:6

    Topics: Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Femoral Artery; Hype

2009
The loss of hypoxic ventilatory responses following resuscitation after cardiac arrest in rats is associated with failure of long-term survival.
    Brain research, 2009, Mar-03, Volume: 1258

    Topics: Animals; Brain Stem; Disease Models, Animal; Heart Arrest; Hypoxia-Ischemia, Brain; Male; Plethysmog

2009
FK506 induces changes in muscle properties and promotes metabosensitive nerve fiber regeneration.
    Journal of neurotrauma, 2009, Volume: 26, Issue:1

    Topics: Animals; Disease Models, Animal; Growth Cones; Immunosuppressive Agents; Lactic Acid; Male; Muscle F

2009
Greater fractalkine expression in mesenteric arteries of female spontaneously hypertensive rats compared with males.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:4

    Topics: Acetylcholine; Animals; Chemokine CCL2; Chemokine CX3CL1; Disease Models, Animal; Female; Hypertensi

2009
Inhibition of Ca(2+)-dependent glutamate release from cerebral cortex synaptosomes of rats with experimental autoimmune encephalomyelitis.
    Journal of neurochemistry, 2009, Volume: 108, Issue:4

    Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Cattle; Cerebral Cortex; Cytosol; Disease Mod

2009
The contribution of Ca2+ signaling and Ca2+ sensitivity to the regulation of airway smooth muscle contraction is different in rats and mice.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:6

    Topics: Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Bronchoconstrictor Agents;

2009
Exposure to supplemental oxygen downregulates antioxidant enzymes and increases pulmonary arterial contractility in premature lambs.
    Neonatology, 2009, Volume: 96, Issue:3

    Topics: Animals; Animals, Newborn; Catalase; Disease Models, Animal; Down-Regulation; Drug Interactions; Ges

2009
Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:7

    Topics: Animals; Disease Models, Animal; Humans; Hypertrophy; In Vitro Techniques; Indoles; Male; Maleimides

2009
Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models.
    Annals of neurology, 2009, Volume: 65, Issue:4

    Topics: Animals; Anticonvulsants; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; El

2009
Time course of alterations in pre- and post-synaptic chemoreceptor function during developmental hyperoxia.
    Respiratory physiology & neurobiology, 2009, Sep-30, Volume: 168, Issue:3

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Calcium; Carotid Body; Catecholamines;

2009
Neuromuscular recovery pattern after medial collateral ligament disruption in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Femoral Nerve; Hindlimb; Knee Injuries; Knee Joint; Lactic

2009
Complete brain-type creatine kinase deficiency in mice blocks seizure activity and affects intracellular calcium kinetics.
    Epilepsia, 2010, Volume: 51, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Calcium; Creatine Kinase; Creatine Kinase, BB Form; Creatine Kinas

2010
Mechanoenergetic function and troponin T release following cardioplegic arrest induced by St Thomas' and histidine-tryptophan-ketoglutarate cardioplegia--an experimental comparative study in pigs.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:4

    Topics: Animals; Bicarbonates; Biomarkers; Calcium Chloride; Cardioplegic Solutions; Cardiopulmonary Bypass;

2009
p70 Ribosomal S6 kinase is required for airway smooth muscle cell size enlargement but not increased contractile protein expression.
    American journal of respiratory cell and molecular biology, 2010, Volume: 42, Issue:6

    Topics: Airway Remodeling; Animals; Asthma; Cell Enlargement; Cells, Cultured; Contractile Proteins; Cytokin

2010
Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:4

    Topics: Acetylcholine; Age Factors; Aging; Animals; Aorta; Blood Pressure; Bridged Bicyclo Compounds, Hetero

2009
Reduction of kidney damage by supplementation of vitamins C and E in rats with deoxycorticosterone-salt-induced hypertension.
    Iranian journal of kidney diseases, 2009, Volume: 3, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Calcium Chloride; Desoxycorticosterone; Dietary Supplements; D

2009
Effects of early aging and cerebral hypoperfusion on spreading depression in rats.
    Neurobiology of aging, 2011, Volume: 32, Issue:9

    Topics: Aging; Animals; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Cor

2011
Susceptibility to stress in young rats after 2-week zinc deprivation.
    Neurochemistry international, 2010, Volume: 56, Issue:3

    Topics: Animals; Brain Chemistry; Corticosterone; Depressive Disorder; Dietary Supplements; Disease Models,

2010
Keratinocytes acting on injured afferents induce extreme neuronal hyperexcitability and chronic pain.
    Pain, 2010, Volume: 148, Issue:1

    Topics: Action Potentials; Analysis of Variance; Animals; Axons; Cell Transplantation; Cells, Cultured; Dise

2010
Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:4

    Topics: Alginates; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Disease Models, A

2010
Role of c-Jun N-terminal kinase in the regulation of vascular tone.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:1

    Topics: Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-R

2010
Thyroid hormone modulates the responsiveness of rat aorta to alpha1-adrenergic stimulation: an effect due to increased activation of beta2-adrenergic signaling.
    International angiology : a journal of the International Union of Angiology, 2009, Volume: 28, Issue:6

    Topics: Acetylcholine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-2 Re

2009
A comparison of hypothermic machine perfusion versus static cold storage in an experimental model of renal ischemia reperfusion injury.
    Transplantation, 2010, Apr-15, Volume: 89, Issue:7

    Topics: Acid-Base Equilibrium; Adenosine; Allopurinol; Animals; Aspartate Aminotransferases; Biomarkers; Cit

2010
Herpes simplex virus type 1 infection of the rat enteric nervous system evokes small-bowel neuromuscular abnormalities.
    Gastroenterology, 2010, Volume: 138, Issue:5

    Topics: Acetylcholine; Animals; Calcium Chloride; Carbachol; CD3 Complex; Disease Models, Animal; Dose-Respo

2010
Cardioprotection afforded by St Thomas solution is enhanced by emulsified isoflurane in an isolated heart ischemia reperfusion injury model in rats.
    Journal of cardiothoracic and vascular anesthesia, 2010, Volume: 24, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Creatine K

2010
Diffuse brain injury elevates tonic glutamate levels and potassium-evoked glutamate release in discrete brain regions at two days post-injury: an enzyme-based microelectrode array study.
    Journal of neurotrauma, 2010, Volume: 27, Issue:5

    Topics: Animals; Brain Injuries; Diffuse Axonal Injury; Disease Models, Animal; Enzyme Assays; Glutamic Acid

2010
Evaluation of exercise and potassium chloride supplementation on blood pressure and nociceptive threshold in hypertensive rats.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2010, Volume: 35, Issue:2

    Topics: Animals; Blood Pressure; Dietary Supplements; Disease Models, Animal; Exercise Therapy; Hypertension

2010
Altered calcium signaling in an experimental model of glaucoma.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:12

    Topics: Adenosine Triphosphate; Animals; Axons; Calcium; Calcium Signaling; Carbachol; Cholinergic Agonists;

2010
Alterations of glutamate release in the spinal cord of mice with experimental autoimmune encephalomyelitis.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Animals; Aspartic Acid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female;

2010
Generation and analysis of the thiazide-sensitive Na+ -Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome.
    Human mutation, 2010, Volume: 31, Issue:12

    Topics: Animals; Base Sequence; Calcium Channels; Cell Size; Codon, Nonsense; Diet; Disease Models, Animal;

2010
Erythropoietin as additive of HTK preservation solution in cold ischemia/reperfusion injury of steatotic livers.
    The Journal of surgical research, 2012, Volume: 173, Issue:1

    Topics: Animals; Cold Temperature; Disease Models, Animal; Erythropoietin; Fatty Liver; Female; Glucose; Ion

2012
Neuromuscular recovery after medial collateral ligament disruption and eccentric rehabilitation program.
    Medicine and science in sports and exercise, 2011, Volume: 43, Issue:6

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Female; H-Reflex; Hindlimb; Knee Injuries; La

2011
Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors?
    The Annals of thoracic surgery, 2011, Volume: 91, Issue:3

    Topics: Animals; Cold Temperature; Disaccharides; Disease Models, Animal; Electrolytes; Glucose; Glutamates;

2011
[A new experimental model for inducing interstitial cystitis by oxidative stress using bladder instillation of a nitric oxide donor gel].
    Actas urologicas espanolas, 2011, Volume: 35, Issue:5

    Topics: Administration, Intravesical; Animals; Chemotaxis, Leukocyte; Cystitis, Interstitial; Disease Models

2011
Dopamine release from serotonergic nerve fibers is reduced in L-DOPA-induced dyskinesia.
    Journal of neurochemistry, 2011, Volume: 118, Issue:1

    Topics: Adrenergic Agents; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopa Decarboxylase

2011
Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:2

    Topics: Animals; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, D

2011
Effect of hyperglycemia on the changes of intracellular [Ca2+]i in heart myoblast.
    The Chinese journal of physiology, 2010, Oct-31, Volume: 53, Issue:5

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Antioxidants; Calcium; Cardiotonic

2010
The effect of intravesical acetylsalicylic acid instillation on tissue prostaglandin levels after partial bladder outlet obstruction in rabbits.
    Neurourology and urodynamics, 2011, Volume: 30, Issue:8

    Topics: Administration, Intravesical; Animals; Aspirin; Carbachol; Collagen; Dinoprost; Dinoprostone; Diseas

2011
Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d

2011
Impact of venous systemic oxygen persufflation supplemented with nitric oxide gas on cold-stored, warm ischemia-damaged experimental liver grafts.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2012, Volume: 18, Issue:2

    Topics: Animals; Biomarkers; Cold Temperature; Disease Models, Animal; Gases; Glucose; Lipid Peroxidation; L

2012
Impact of Plasma-Lyte pH 7.4 on acid-base status and hemodynamics in a model of controlled hemorrhagic shock.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:11

    Topics: Acid-Base Equilibrium; Animals; Crystalloid Solutions; Disease Models, Animal; Epidemiologic Methods

2011
Ischaemic postconditioning: does cardioplegia influence protection?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2012, Volume: 42, Issue:3

    Topics: Animals; Bicarbonates; Calcium Chloride; Coronary Circulation; Disease Models, Animal; Heart Arrest,

2012
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction.
    Nature medicine, 2012, Mar-04, Volume: 18, Issue:4

    Topics: Analysis of Variance; Animals; Asthma; CD11c Antigen; CD4 Antigens; Dendritic Cells; Disease Models,

2012
The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:11

    Topics: Amides; Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Disease Models, Animal;

2012
Potassium induced cardiac standstill during conventional cardiopulmonary resuscitation in a pig model of prolonged ventricular fibrillation cardiac arrest: a feasibility study.
    Resuscitation, 2013, Volume: 84, Issue:3

    Topics: Animals; Cardioplegic Solutions; Cardiopulmonary Resuscitation; Disease Models, Animal; Feasibility

2013
Study of heparin in intestinal ischemia and reperfusion in rats: morphologic and functional evaluation.
    Transplantation proceedings, 2012, Volume: 44, Issue:8

    Topics: Animals; Cytoprotection; Disease Models, Animal; Electric Stimulation; Enteric Nervous System; Gastr

2012
Effect of ischemic preconditioning on injuries caused by ischemia and reperfusion in rat intestine.
    Transplantation proceedings, 2012, Volume: 44, Issue:8

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Enteric Nervous System; Gastrointestinal Moti

2012
Study of L-arginine in intestinal lesions caused by ischemia-reperfusion in rats.
    Transplantation proceedings, 2012, Volume: 44, Issue:8

    Topics: Animals; Arginine; Cytoprotection; Disease Models, Animal; Electric Stimulation; Enteric Nervous Sys

2012
Effect of adenosine on injury caused by ischemia and reperfusion in rats: functional and morphologic study.
    Transplantation proceedings, 2012, Volume: 44, Issue:8

    Topics: Adenosine; Animals; Cytoprotection; Disease Models, Animal; Electric Stimulation; Enteric Nervous Sy

2012
Atenolol to treat intestinal ischemia and reperfusion in rats.
    Transplantation proceedings, 2012, Volume: 44, Issue:8

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Atenolol; Cytoprotection; Disease Models, Animal; E

2012
Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease.
    BMC neuroscience, 2012, Oct-06, Volume: 13

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Dopaminer

2012
Transsynaptic signaling by activity-dependent cleavage of neuroligin-1.
    Neuron, 2012, Oct-18, Volume: 76, Issue:2

    Topics: Animals; Animals, Newborn; Biotinylation; Calcium-Binding Proteins; Cell Adhesion Molecules, Neurona

2012
Role of PKC and CaV1.2 in detrusor overactivity in a model of obesity associated with insulin resistance in mice.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Adiposity; Amlodipine; Animals; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Cal

2012
Maternal separation increases GABA(A) receptor-mediated modulation of norepinephrine release in the hippocampus of a rat model of ADHD, the spontaneously hypertensive rat.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Attention Deficit Disorder with Hypera

2013
New HTK-N46B cardioplegia provides superior protection during ischemia/reperfusion in failing hearts.
    The Journal of cardiovascular surgery, 2013, Volume: 54, Issue:3

    Topics: Animals; Biomarkers; Cardiac Surgical Procedures; Cardioplegic Solutions; Disease Models, Animal; Gl

2013
Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice.
    The Journal of biological chemistry, 2002, Oct-04, Volume: 277, Issue:40

    Topics: Aging; Animals; Bartter Syndrome; Base Sequence; Cell Membrane; Disease Models, Animal; DNA Primers;

2002
Tempol selectively attenuates angiotensin II evoked vasoconstrictor responses in spontaneously hypertensive rats.
    Journal of hypertension, 2002, Volume: 20, Issue:7

    Topics: Angiotensin II; Animals; Aorta; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship,

2002
Effect of partial outlet obstruction on rabbit urinary bladder smooth muscle function.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:4

    Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; In Vitro Techniques; Isometric Con

2003
Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model.
    Pediatric research, 2003, Volume: 53, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Airway Obstructio

2003
Intravesical protamine sulfate and potassium chloride as a model for bladder hyperactivity.
    Urology, 2003, Volume: 61, Issue:3

    Topics: Administration, Intravesical; Animals; Capsaicin; Cystitis, Interstitial; Disease Models, Animal; Do

2003
Effects of acute rejection on L-arginine/iNOS pathway in canine heart transplantation.
    The Canadian journal of cardiology, 2003, Mar-31, Volume: 19, Issue:4

    Topics: Animals; Arginine; Coronary Vessels; Dinoprost; Disease Models, Animal; Dogs; Endothelium, Vascular;

2003
Change in lipid profile and impairment of endothelium-dependent relaxation of blood vessels in rats after bile duct ligation.
    Life sciences, 2003, Jul-25, Volume: 73, Issue:10

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteriosclerosis; Bile Ducts; Disease Models, Animal; Dose-

2003
Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle-aged rats.
    Brain research, 2003, Aug-15, Volume: 981, Issue:1-2

    Topics: Aging; Animals; Benzoxazoles; Blood Gas Analysis; Blood Pressure; Carrier Proteins; Cerebral Cortex;

2003
The effects of paroxetine on rat isolated vas deferens.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2003
An electrophysiological model of spinal transmission deficits in mouse experimental autoimmune encephalomyelitis.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1

    Topics: Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Disease Models, Anim

2004
Altered temporal pattern of mechanically evoked C-fiber activity in a model of diabetic neuropathy in the rat.
    Neuroscience, 2003, Volume: 121, Issue:4

    Topics: Action Potentials; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models,

2003
Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition.
    Journal of the Society for Gynecologic Investigation, 2004, Volume: 11, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Female; Fetu

2004
Comparison of hyperkalemic cardioplegia with altered [CaCl2] and [MgCl2] on [Ca2+]i transients and function after warm global ischemia in isolated hearts.
    The Journal of cardiovascular surgery, 2004, Volume: 45, Issue:1

    Topics: Animals; Calcium; Calcium Chloride; Cardioplegic Solutions; Coronary Circulation; Cytosol; Diastole;

2004
Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil.
    Planta medica, 2004, Volume: 70, Issue:4

    Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Desoxycorticosterone; Disease Models, Anima

2004
Intra-arrest cooling improves outcomes in a murine cardiac arrest model.
    Circulation, 2004, Jun-08, Volume: 109, Issue:22

    Topics: Animals; Coronary Circulation; Disease Models, Animal; Female; Heart Arrest; Hyperkalemia; Hypotherm

2004
Evaluation of pelvic contractility in ureteropelvic junction obstruction: an experimental study.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2004, Volume: 14, Issue:2

    Topics: Animals; Disease Models, Animal; Female; Free Radical Scavengers; In Vitro Techniques; Muscle Contra

2004
Regulation of ion channel localization and phosphorylation by neuronal activity.
    Nature neuroscience, 2004, Volume: 7, Issue:7

    Topics: Animals; Animals, Newborn; Blotting, Western; Cadmium Chloride; Calcimycin; Calcium Channel Blockers

2004
Suppressive effect of Saiko-ka-ryukotsu-borei-to, a herbal medicine, on excessive release of glutamate in the hippocampus.
    Brain research bulletin, 2004, Sep-30, Volume: 64, Issue:3

    Topics: Animals; Body Weight; Disease Models, Animal; Drugs, Chinese Herbal; Excitatory Amino Acid Antagonis

2004
Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington's disease.
    Experimental neurology, 2004, Volume: 190, Issue:1

    Topics: Animals; Cell Differentiation; Cell Line; Cell Proliferation; Cells, Cultured; Disease Models, Anima

2004
Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:5

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Canada; Cromakalim; Desoxycorticos

2004
Mechanisms underlying quercetin-induced vasorelaxation in aorta of subchronic diabetic rats: an in vitro study.
    Vascular pharmacology, 2004, Volume: 42, Issue:1

    Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Model

2004
Ocular inflammation alters swelling and membrane characteristics of rat Müller glial cells.
    Journal of neuroimmunology, 2005, Volume: 161, Issue:1-2

    Topics: Analysis of Variance; Animals; Cell Size; Cells, Cultured; Disease Models, Animal; Dose-Response Rel

2005
Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats.
    Journal of neurochemistry, 2005, Volume: 93, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Interactions; Epilepsy; Glutamic Acid; Hippocampus; Kainic Aci

2005
Effects of chronic quercetin treatment in experimental renovascular hypertension.
    Molecular and cellular biochemistry, 2005, Volume: 270, Issue:1-2

    Topics: Animals; Antioxidants; Aorta; Blood Pressure; Body Weight; Diet; Disease Models, Animal; Dose-Respon

2005
Antiepileptic action induced by a combination of vigabatrin and tiagabine.
    Neuroscience, 2005, Volume: 132, Issue:2

    Topics: Action Potentials; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Dru

2005
Phenotypic modifications of vascular smooth muscle cells could be responsible for vascular hyporeactivity to contracting agent in mechanically injured rat carotid artery.
    Atherosclerosis, 2005, Volume: 183, Issue:2

    Topics: Actins; Angioplasty, Balloon; Animals; Blotting, Western; Calcium; Calcium Channels; Calcium-Transpo

2005
Differential inhibitory effects of honokiol and magnolol on excitatory amino acid-evoked cation signals and NMDA-induced seizures.
    Neuropharmacology, 2005, Volume: 49, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Biphenyl Compounds; Calcium; Cells, Cultured; Ce

2005
Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:1

    Topics: Animals; Brain Ischemia; Cardiopulmonary Resuscitation; Cell Death; Disease Models, Animal; Heart Ar

2006
Functional assessment of vascular reactivity after chronic intermittent hypoxia in the rat.
    Respiratory physiology & neurobiology, 2006, Feb-28, Volume: 150, Issue:2-3

    Topics: Analysis of Variance; Animals; Aorta; Carotid Arteries; Chronic Disease; Disease Models, Animal; Dos

2006
Functional role of prostacyclin receptor in rat dorsal root ganglion neurons.
    Neuroscience letters, 2005, Nov-18, Volume: 388, Issue:3

    Topics: Animals; Animals, Newborn; Capsaicin; Cells, Cultured; Cyclic AMP; Cystitis, Interstitial; Disease M

2005
MitoKATP-channel opener protects against neuronal death in rat venous ischemia.
    Neurosurgery, 2005, Volume: 57, Issue:2

    Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Brain Edema; Brain Infarction; Cell Death; Ce

2005
Reversal of cardiac dysfunction by selective ET-A receptor antagonism.
    British journal of pharmacology, 2005, Volume: 146, Issue:6

    Topics: Acetylcholine; Action Potentials; Animals; Aorta, Thoracic; Atrasentan; Body Weight; Collagen; Desox

2005
Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction.
    Endocrinology, 2006, Volume: 147, Issue:3

    Topics: Animals; Arginine; Body Temperature; Catecholamines; Disease Models, Animal; Female; Fetal Growth Re

2006
Effect of pressure overload and its recovery on the rat carotid artery: change of vascular reactivity and remodeling process.
    Heart and vessels, 2006, Volume: 21, Issue:1

    Topics: Acetylcholine; Animals; Apoptosis; Blood Pressure; Blotting, Western; Carotid Artery, Common; Diseas

2006
Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats.
    Neuroscience, 2006, Jun-30, Volume: 140, Issue:2

    Topics: Animals; Cerebral Cortex; Cerebral Infarction; Cortical Spreading Depression; Cyclooxygenase 2; Cycl

2006
Release of vesicular Zn2+ in a rat transient middle cerebral artery occlusion model.
    Brain research bulletin, 2006, May-31, Volume: 69, Issue:6

    Topics: Animals; Brain; Disease Models, Animal; Extracellular Space; Infarction, Middle Cerebral Artery; Mal

2006
Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylamines.
    Brain research, 2006, Jun-20, Volume: 1095, Issue:1

    Topics: Aldehydes; Animals; Behavior, Animal; Cell Line; Cyclic N-Oxides; Disease Models, Animal; Dose-Respo

2006
Decreased vascular reactivity to alpha1 adrenergic stimulation in the presence of hypothyroid state: a part of an adaptive response?
    International angiology : a journal of the International Union of Angiology, 2006, Volume: 25, Issue:2

    Topics: Adaptation, Biological; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Disease Models, Animal;

2006
Protective effect of potassium against the hypertensive cardiac dysfunction: association with reactive oxygen species reduction.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:2

    Topics: Animals; Blood Pressure; Body Weight; Dietary Supplements; Disease Models, Animal; Echocardiography;

2006
Noradrenaline-induced contraction of mice aorta is enhanced in schistosomiasis.
    Vascular pharmacology, 2007, Volume: 46, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Calcium Channels, L-Type; Calcium Signaling; Disea

2007
Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth.
    Experimental brain research, 2007, Volume: 177, Issue:3

    Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Central Nervous System Stimu

2007
Reduced threshold for cortical spreading depression in female mice.
    Annals of neurology, 2007, Volume: 61, Issue:6

    Topics: Animals; Cortical Spreading Depression; Disease Models, Animal; Dose-Response Relationship, Drug; El

2007
Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:6

    Topics: Amino Acids; Analysis of Variance; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Li

2008
Masking epilepsy by combining two epilepsy genes.
    Nature neuroscience, 2007, Volume: 10, Issue:12

    Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Calcium Channel Blockers; Calcium Channels, N-Typ

2007
Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Down-Regulation; Excitator

2008
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.
    Cardiovascular research, 2008, Apr-01, Volume: 78, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Blotti

2008
ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro.
    Biochemical and biophysical research communications, 2008, Mar-28, Volume: 368, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Connexins; Cyclic AMP-Dependent Protein Kinases; Dis

2008
Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Animals; Arterioles; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Anima

2008
Attenuated cold storage injury of rat livers using a modified HTK solution.
    The Journal of surgical research, 2008, May-01, Volume: 146, Issue:1

    Topics: Animals; Apoptosis; Bile; Blood Pressure; Cryopreservation; Disease Models, Animal; Glucose; Heart R

2008
Effect of exercise training on aortic tone in chronic renal insufficiency.
    American journal of hypertension, 2008, Volume: 21, Issue:5

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Disease Models, Animal; Dose-Response Relationship, Drug; M

2008
Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veins.
    Journal of vascular surgery, 2008, Volume: 48, Issue:2

    Topics: Angiotensin II; Animals; Biomarkers; Disease Models, Animal; Endothelium, Vascular; Immunoblotting;

2008
Hypophosphaturia impairs the renal defense against metabolic acidosis.
    Kidney international, 1984, Volume: 26, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Bicarbonates; Chlorides; Creatinine; Disease Models, Anima

1984
Seizure-like spreading depression in immature rabbit hippocampus in vitro.
    Brain research, 1984, Volume: 316, Issue:1

    Topics: Animals; Bicuculline; Disease Models, Animal; Electrophysiology; Epilepsy; Hippocampus; In Vitro Tec

1984
Force generation in experimental tetanus, KCl contracture, and oxygen and glucose deficiency contracture in mammalian myocardium.
    Pflugers Archiv : European journal of physiology, 1983, Volume: 396, Issue:4

    Topics: Animals; Cats; Disease Models, Animal; Glucose; Myocardial Contraction; Oxygen; Potassium Chloride;

1983
New theory of the development of myocardial infarction.
    Acta physiologica Academiae Scientiarum Hungaricae, 1982, Volume: 59, Issue:3

    Topics: Animals; Disease Models, Animal; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Hypoxia; Mal

1982
Ventricular tachyarrhythmias in regional myocardial hyperkalemia: efficacy of three antiarrhythmic agents.
    Journal of electrocardiology, 1980, Volume: 13, Issue:2

    Topics: Animals; Coronary Disease; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction Syste

1980
Percutaneous transluminal angioplasty in a canine model of cerebral vasospasm: angiographic, histologic, and pharmacologic evaluation.
    Surgical neurology, 1995, Volume: 44, Issue:2

    Topics: Angioplasty; Animals; Catheterization; Cerebral Angiography; Disease Models, Animal; Dogs; Dose-Resp

1995
Effect of partial outlet obstruction on contractility: comparison between severe and mild obstruction.
    Neurourology and urodynamics, 1993, Volume: 12, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Disease Models, Animal; Electri

1993
Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; B

1994
Magnesium modulates endothelial dysfunction produced by elevated glucose incubation.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Acetylcholine; Analysis of Variance; Animals; Aorta; Diabetes Mellitus, Experimental; Disease Models

1994
Prevention and reduction of neural damage in ischemic strokes by w-(N,N'-diethylamino)-n-alkyl-3,4,5-trimethoxybenzoate compounds.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Animals; Aorta; Brain Ischemia; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex;

1995
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An

1995
SB 201823-A antagonizes calcium currents in central neurons and reduces the effects of focal ischemia in rats and mice.
    Stroke, 1995, Volume: 26, Issue:9

    Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cereb

1995
Vascular reactivity to vasoconstrictors in aorta and renal vasculature of hyperthyroid and hypothyroid rats.
    Pharmacology, 1994, Volume: 49, Issue:4

    Topics: Animals; Aorta, Thoracic; Barium Compounds; Blood Pressure; Chlorides; Disease Models, Animal; Dose-

1994
Third place winner of the Conrad Jobst Award in the gold medal paper competition. Prevention of spinal cord dysfunction in a new model of spinal cord ischemia.
    The American surgeon, 1995, Volume: 61, Issue:1

    Topics: Acetates; Animals; Aorta; Cardioplegic Solutions; Disease Models, Animal; Drug Evaluation, Preclinic

1995
Tolerance of the developing heart to ischemia: impact of hypoxemia from birth.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Age Factors; Animals; Animals, Newborn; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Crea

1995
Time course of perfusion-induced myocardial edema resolution in rats.
    The Journal of surgical research, 1994, Volume: 57, Issue:6

    Topics: Animals; Bicarbonates; Body Water; Calcium Chloride; Disease Models, Animal; Edema, Cardiac; Magnesi

1994
Preservation of peripheral nerve grafts: a comparison of normal saline, HTK organ preservation solution, and DMEM Schwann cell culture medium.
    Journal of reconstructive microsurgery, 1995, Volume: 11, Issue:6

    Topics: Animals; Cardioplegic Solutions; Cell Division; Cell Survival; Cryopreservation; Culture Media; Dise

1995
Augmented responses to 5-HT2-receptor-mediated vasoconstrictions in atherosclerotic rabbit common carotid arteries.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriosclerosis; Carotid Arteries; Disease Models,

1995
Vascular hyporesponsiveness in aorta from portal hypertensive rats: possible sites of involvement.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:2

    Topics: Animals; Aorta; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Muscle

1996
Modification of aortic contractility in the cardiomyopathic hamster.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cricetinae; Disease Models, Animal; Dose-Re

1996
Loss of endothelium-mediated vascular relaxation as a response to various clamping pressures.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1996, Volume: 10, Issue:8

    Topics: Adrenergic alpha-Agonists; Animals; Carbachol; Constriction; Dilatation, Pathologic; Disease Models,

1996
Intranigral ventral mesencephalic grafts and nigrostriatal injections of glial cell line-derived neurotrophic factor restore dopamine release in the striatum of 6-hydroxydopamine-lesioned rats.
    Experimental brain research, 1998, Volume: 119, Issue:3

    Topics: Animals; Behavior, Animal; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; Do

1998
Use of abdominal fascia to create partial outlet obstruction in rabbits.
    Neurourology and urodynamics, 1998, Volume: 17, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbachol; Disease Models, Animal; Electric Stimulation; Male; Musc

1998
Advantages of continuous hyperpolarized arrest with pinacidil over St. Thomas' Hospital solution during prolonged ischemia.
    The Journal of thoracic and cardiovascular surgery, 1998, Volume: 116, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Bicarbonates; Body Water; Calcium Chloride; Cardioplegic Solutions; C

1998
Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemia followed by reoxygenation.
    Pharmacology, 1998, Volume: 57, Issue:3

    Topics: Animals; Carbachol; Cell Hypoxia; Disease Models, Animal; Electric Stimulation; Glucose; In Vitro Te

1998
Function of adult pig hearts after 2 and 12 hours of cold cardioplegic preservation.
    The Annals of thoracic surgery, 1998, Volume: 66, Issue:1

    Topics: Animals; Bicarbonates; Blood; Calcium Chloride; Cardiac Catheterization; Cardiac Output; Cardioplegi

1998
Effects of moderate, central fluid percussion traumatic brain injury on nitric oxide synthase activity in rats.
    Journal of neurotrauma, 1998, Volume: 15, Issue:8

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Brain Injuries; Cerebral Cortex; Cerebrovas

1998
Experimental study on the scavenging effects of ginsenosides on oxygen free radicals using model of heterotopic heart transplantation in rats.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 1998, Volume: 4, Issue:4

    Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Disease Models, Animal; Female; Fre

1998
Altered mitochondrial oxidative phosphorylation in hippocampal slices of kainate-treated rats.
    Brain research, 1999, May-01, Volume: 826, Issue:2

    Topics: Animals; Benzimidazoles; Calcium; Chelating Agents; Coloring Agents; Disease Models, Animal; Egtazic

1999
Exercise training does not alter acetylcholine-induced responses in isolated pulmonary artery from rat.
    The European respiratory journal, 1999, Volume: 13, Issue:3

    Topics: Acetylcholine; Animals; Cardiomegaly; Culture Techniques; Dinoprost; Disease Models, Animal; Male; M

1999
Low-potassium University of Wisconsin solution for cardioplegia: improved protection of the isolated ischemic neonatal rabbit heart.
    Cardiovascular surgery (London, England), 1999, Volume: 7, Issue:7

    Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Animals, Newborn; Bicarbonates; Calcium Chl

1999
Effects of cortical spreading depression on cortical blood flow, impedance, DC potential, and infarct size in a rat venous infarct model.
    Experimental neurology, 2000, Volume: 162, Issue:1

    Topics: Acute Disease; Animals; Blood Gas Analysis; Brain Mapping; Cerebral Infarction; Cerebral Veins; Cere

2000
Ischemic preconditioning and infarct mass: the effect of hypercholesterolemia and endothelial dysfunction.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2000, Volume: 22, Issue:2

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Calcimycin; Cholesterol; Diet, Atherogenic; Disease Mode

2000
High-calcium diet enhances vasorelaxation in nitric oxide-deficient hypertension.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium, Di

2000
Assessment of viability of the liver graft in different cardiac arrest models.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Alanine Transaminase; Animals; Carbon Dioxide; Disease Models, Animal; Graft Survival; Heart Arrest;

2000
Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: Acetylcholine; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Disease Models, Animal; D

2001
Postischemic cardiac function recovery in the isolated rat heart: effects of adenosine deaminase and nucleoside transport inhibition.
    Langenbeck's archives of surgery, 2000, Volume: 385, Issue:8

    Topics: Adenine; Adenosine Deaminase; Affinity Labels; Animals; Cardioplegic Solutions; Disease Models, Anim

2000
Lead-cadmium interaction effect on the responsiveness of rat mesenteric vessels to norepinephrine and angiotensin II.
    Toxicology, 2001, May-21, Volume: 162, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Animals; Cadmium Poisoning; Calcium; Dinoprostone; Disease Mod

2001
A reliable, nondestructive animal model for interstitial cystitis: intravesical low-dose protamine sulfate combined with physiological concentrations of potassium chloride.
    Urology, 2001, Volume: 57, Issue:6 Suppl 1

    Topics: Animals; Cystitis, Interstitial; Disease Models, Animal; Female; Heparin Antagonists; Potassium Chlo

2001
Ethanol blocks cytosolic Ca2+ responses triggered by activation of GABA(A) receptor/Cl- channels in cultured proliferating rat neuroepithelial cells.
    Neuroscience, 2001, Volume: 104, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Divisi

2001
Enhanced calcium influx in hippocampal CA3 neurons of spontaneously epileptic rats.
    Epilepsia, 2001, Volume: 42, Issue:3

    Topics: Animals; Calcium; Calcium Channels; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationshi

2001
Vasospasm in monkeys resolves because of loss of and encasement of subarachnoid blood clot.
    Stroke, 2001, Volume: 32, Issue:8

    Topics: Analysis of Variance; Animals; Basilar Artery; Cerebral Angiography; Disease Models, Animal; Disease

2001
Influence of lead on rat thoracic aorta contraction and relaxation.
    American journal of hypertension, 2001, Volume: 14, Issue:9 Pt 1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium; Disease Models, Animal; Dose-Response Relationship

2001
Capsaicin-evoked CGRP release from rat buccal mucosa: development of a model system for studying trigeminal mechanisms of neurogenic inflammation.
    The European journal of neuroscience, 2001, Volume: 14, Issue:7

    Topics: Animals; Bradykinin; Calcimycin; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Dinoprostone;

2001
Activity of thalamic reticular neurons during spontaneous genetically determined spike and wave discharges.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Mar-15, Volume: 22, Issue:6

    Topics: Action Potentials; Animals; Disease Models, Animal; Electric Stimulation; Electrodes; Electroencepha

2002
Advantages of potassium cardioplegia and perfusion hypothermia in left ventricular hypertrophy.
    The Annals of thoracic surgery, 1977, Volume: 24, Issue:4

    Topics: Adenosine Triphosphate; Animals; Cardiomegaly; Creatine Kinase; Disease Models, Animal; Dogs; Electr

1977
Effects of glucose, insulin and potassium infusion on tissue metabolic changes within first hour of myocardial infarction in the baboon.
    Circulation, 1975, Volume: 52, Issue:1

    Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Creatine; Disease Models, Animal; Dogs; Female; G

1975
Identification of susceptibility to malignant hyperpyrexia in swine.
    British journal of anaesthesia, 1979, Volume: 51, Issue:3

    Topics: Animals; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Tec

1979
Hypertension, transmural pressure, and vascular smooth muscle response in rats.
    Circulation research, 1975, Volume: 36, Issue:5

    Topics: Animals; Arteries; Calcium; Calcium Chloride; Desoxycorticosterone; Disease Models, Animal; Epinephr

1975
Termination of ventricular fibrillation in dogs by depolarizing a critical amount of myocardium.
    The American journal of cardiology, 1975, Volume: 36, Issue:1

    Topics: Animals; Cardiopulmonary Bypass; Coronary Vessels; Disease Models, Animal; Dogs; Electroshock; Heart

1975
Vasodilator responses to K+ in genetic hypertensive and in renal hypertensive rats.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:6

    Topics: Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Hypertension; Hypertension,

1975
Steroid-induced polycystic kidneys in the newborn rat.
    The American journal of pathology, 1976, Volume: 82, Issue:2

    Topics: Animals; Animals, Newborn; Bicarbonates; Disease Models, Animal; Electrolytes; Female; Kidney Diseas

1976
Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:3

    Topics: Animals; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Disease Models, Anim

1992
A novel approach for the determination of the pain-producing potential of intravenously injected substances in the conscious rat.
    Pharmaceutical research, 1992, Volume: 9, Issue:2

    Topics: Animals; Disease Models, Animal; Injections, Intravenous; Male; Morphine; Pain; Pain Measurement; Po

1992
Effect of hyperkalemia on experimental myocardial depression by verapamil.
    American heart journal, 1991, Volume: 121, Issue:2 Pt 1

    Topics: Acute Disease; Animals; Bradycardia; Calcium; Depression, Chemical; Disease Models, Animal; Dogs; Dr

1991
[A method of modeling of occlusion-reperfusion induced myocardial infarction and quantitative evaluation of the effectiveness of limitation of its size].
    Kardiologiia, 1990, Volume: 30, Issue:7

    Topics: Animals; Carotid Arteries; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Mat

1990
A rat model for hyperkalemia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 185, Issue:1

    Topics: Amiloride; Animals; Disease Models, Animal; Hyperkalemia; Male; Potassium; Potassium Chloride; Rats;

1987
Potassium-aldosterone response in dogs with chronic renal insufficiency.
    Mineral and electrolyte metabolism, 1985, Volume: 11, Issue:3

    Topics: Aldosterone; Animals; Disease Models, Animal; Dogs; Female; Glomerular Filtration Rate; Kidney Failu

1985
Topical acidification promotes healing of experimental deep partial thickness skin burns: a randomized double-blind preliminary study.
    Burns, including thermal injury, 1985, Volume: 12, Issue:2

    Topics: Administration, Topical; Animals; Buffers; Burns; Disease Models, Animal; Double-Blind Method; Femal

1985
After-discharge bursts in cobalt and penicillin foci in primate cortex.
    Electroencephalography and clinical neurophysiology, 1973, Volume: 34, Issue:3

    Topics: Action Potentials; Alpha Rhythm; Animals; Cerebral Cortex; Cobalt; Cortical Spreading Depression; Di

1973
[Ultrastructural basis for one type of block of ectopic excitation in the myocardium].
    Kardiologiia, 1971, Volume: 11, Issue:6

    Topics: Animals; Disease Models, Animal; Dogs; Heart Block; Inclusion Bodies; Lipids; Methods; Microscopy, E

1971
The effects of spreading depression on penicillin-induced epileptiform activity in rat brain.
    Epilepsia, 1972, Volume: 13, Issue:5

    Topics: Animals; Cerebral Cortex; Corpus Callosum; Cortical Spreading Depression; Disease Models, Animal; El

1972
Observations on the efficiency of dystrophic muscle in vitro.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:4

    Topics: Animals; Caffeine; Disease Models, Animal; Electric Stimulation; Fatigue; In Vitro Techniques; Mice;

1973
Capillary flow and capillary transport in dog skeletal muscle in hemorrhagic shock.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1972, Volume: 4, Issue:1

    Topics: Animals; Autoradiography; Biological Transport; Blood Pressure; Capillary Permeability; Capillary Re

1972
[Influence of air mixed with 10 per cent CO2 inhalation on the electrocardiogram in hyperkalemia].
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1969, Volume: 12, Issue:5

    Topics: Air; Animals; Blood; Carbon Dioxide; Disease Models, Animal; Electrocardiography; Hydrogen-Ion Conce

1969
Dissociation of factors influencing myocardial degeneration and generalized cardiocirculatory failure.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Aspartic Acid; Cricetinae; Diet; Digitoxin; Disease Models, Animal; Edema; Epinephrine; Fem

1969
[Effect of electrolytes and cyanocobalamine on the development of experimental cardiac necrosis].
    Kardiologiia, 1969, Volume: 9, Issue:3

    Topics: Animals; Cardiomyopathies; Chlorides; Disease Models, Animal; Electrocardiography; Immobilization; M

1969
Comparison of polarizing solution and isovolumic KCl in digitalis-induced ventricular tachycardia.
    American heart journal, 1970, Volume: 80, Issue:1

    Topics: Animals; Digitalis; Disease Models, Animal; Dogs; Glucose; Heart Ventricles; Infusions, Parenteral;

1970
Stress and aging.
    Journal of the American Geriatrics Society, 1970, Volume: 18, Issue:9

    Topics: Adaptation, Physiological; Aging; Anabolic Agents; Animals; Calcium Metabolism Disorders; Chlorides;

1970