potassium chloride has been researched along with Diabetes Mellitus in 25 studies
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (56.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chatterjee, R | 1 |
| Davenport, CA | 1 |
| Kwee, L | 1 |
| D'Alessio, D | 1 |
| Svetkey, LP | 1 |
| Lin, PH | 1 |
| Slentz, CA | 1 |
| Ilkayeva, O | 1 |
| Johnson, J | 1 |
| Edelman, D | 1 |
| Shah, SH | 1 |
| West, HL | 1 |
| Corbin, KL | 1 |
| D'Angelo, CV | 1 |
| Donovan, LM | 1 |
| Jahan, I | 1 |
| Gu, G | 1 |
| Nunemaker, CS | 1 |
| Dhatariya, K | 1 |
| Levy, N | 1 |
| Hall, GM | 1 |
| Kamath, V | 1 |
| Kyathanahalli, CN | 1 |
| Jayaram, B | 1 |
| Syed, I | 1 |
| Olson, LK | 1 |
| Ludwig, K | 1 |
| Klumpp, S | 1 |
| Krieglstein, J | 1 |
| Kowluru, A | 1 |
| Gonulalan, U | 1 |
| Kosan, M | 1 |
| Hafez, G | 1 |
| Arıoglu, E | 1 |
| Akdemir, O | 1 |
| Ozturk, B | 1 |
| Gur, S | 1 |
| Cetinkaya, M | 1 |
| LENZI, F | 1 |
| CANIGGIA, A | 1 |
| BOULET, P | 1 |
| SERRE, H | 1 |
| MIROUZE, J | 1 |
| BECHARD, C | 1 |
| Hoa, NK | 1 |
| Phan, DV | 1 |
| Thuan, ND | 1 |
| Ostenson, CG | 1 |
| Poy, MN | 1 |
| Eliasson, L | 1 |
| Krutzfeldt, J | 1 |
| Kuwajima, S | 1 |
| Ma, X | 1 |
| Macdonald, PE | 1 |
| Pfeffer, S | 1 |
| Tuschl, T | 1 |
| Rajewsky, N | 1 |
| Rorsman, P | 1 |
| Stoffel, M | 1 |
| Zhang, C | 1 |
| Moriguchi, T | 1 |
| Kajihara, M | 1 |
| Esaki, R | 1 |
| Harada, A | 1 |
| Shimohata, H | 1 |
| Oishi, H | 1 |
| Hamada, M | 1 |
| Morito, N | 1 |
| Hasegawa, K | 1 |
| Kudo, T | 1 |
| Engel, JD | 1 |
| Yamamoto, M | 1 |
| Takahashi, S | 1 |
| STEPHENS, FI | 1 |
| Cardwell, RJ | 1 |
| Webb, RC | 1 |
| Kontos, HA | 1 |
| Tang, J | 1 |
| Pugh, W | 1 |
| Polonsky, KS | 1 |
| Zhang, H | 1 |
| Gray, AM | 1 |
| Flatt, PR | 1 |
| Harken, AH | 1 |
| Ahmad, I | 1 |
| Davis, L | 1 |
| DeFronzo, RA | 1 |
| Sherwin, RS | 1 |
| Dillingham, M | 1 |
| Hendler, R | 1 |
| Tamborlane, WV | 1 |
| Felig, P | 1 |
| Mantha, S | 1 |
| Rao, SM | 1 |
| Sviatelik, GV | 1 |
| Schneider, H | 1 |
| Ziegelasch, HJ | 1 |
| Roediger, PM | 1 |
| Hutchison, JC | 1 |
| Tschudi-Steiner, I | 1 |
| Conn, HO | 1 |
| Krall, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Potassium on Glucose Metabolism in African Americans[NCT02236598] | Phase 2 | 61 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in glucose tolerance, as measured by change in glucose area-under-the-curve (Area Under the Curve (AUC) - measured via the trapezoidal method) of 2 hours from the 3-hour Oral Glucose Tolerance Test (OGTT). (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | AUC - mg*min/dL (Mean) |
|---|---|
| K+ Supplementation | 328 |
| Placebo | 1000 |
Changes in Insulin Secretion as measured by 2-hour insulin area-under-the-curve (AUC - measured via the trapezoidal method) of 2 hours from the 3-hour OGTT. (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | AUC - pg*min/mL (Mean) |
|---|---|
| K+ Supplementation | 71,444 |
| Placebo | 149,327 |
Matsuda Insulin Sensitivity Index was calculated as: 10,000 / square root of [fasting glucose x fasting insulin x mean glucose x mean insulin during Oral Glucose Tolerance Test]). (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | AUC - unitless, (Mean) |
|---|---|
| K+ Supplementation | -0.03 |
| Placebo | -0.87 |
Changes in fasting, 1-hour, and 2-hour post-challenge glucose levels in mg/dL (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | mg/dL (Mean) | ||
|---|---|---|---|
| Change in Fasting Glucose | Change in 1-Hour Glucose | Change in 2-Hour Glucose | |
| K+ Supplementation | -1.0667 | 0.80 | 3.60 |
| Placebo | 6.0833 | 14.17 | 0.75 |
3 reviews available for potassium chloride and Diabetes Mellitus
| Article | Year |
|---|---|
The impact of glycaemic variability on the surgical patient.
Topics: Blood Glucose; Critical Illness; Diabetes Mellitus; Glucose; Glycated Hemoglobin; Humans; Hyperglyce | 2016 |
The surgical significance of the oxyhemoglobin dissociation curve.
Topics: Anemia; Angina Pectoris; Animals; Blood; Diabetes Mellitus; Diphosphoglyceric Acids; Erythrocytes; H | 1977 |
[Adverse effects of important long-term-therapeutics].
Topics: Acidosis; Animals; Antidepressive Agents; Antitubercular Agents; Biguanides; Central Nervous System; | 1970 |
2 trials available for potassium chloride and Diabetes Mellitus
| Article | Year |
|---|---|
Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease.
Topics: Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Female; Glucose; Humans; Male; Mass Spect | 2020 |
The influence of Rauwolfia serpentina crude root on the fasting blood sugar.
Topics: Aged; Bendroflumethiazide; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Female; Human | 1969 |
20 other studies available for potassium chloride and Diabetes Mellitus
| Article | Year |
|---|---|
Postnatal maturation of calcium signaling in islets of Langerhans from neonatal mice.
Topics: Aging; Animals; Animals, Newborn; Calcium; Calcium Channels, L-Type; Calcium Signaling; Diabetes Mel | 2021 |
Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells.
Topics: Adult; Animals; ATP Citrate (pro-S)-Lyase; Cell Line; Cytosol; Diabetes Mellitus; Energy Metabolism; | 2010 |
The effect of diabetes mellitus on α1-adrenergic receptor subtypes in the bladder of rats.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Diabetes Mellitus; In Vitro Techniques; Male; Muscle | 2012 |
[Potassium chloride poisoning during diabetic coma; significance of the surface potassium gradient on the origin of ECG modifications by action of potassium chloride].
Topics: Diabetes Mellitus; Diabetic Coma; Electrocardiography; Potassium; Potassium Chloride | 1951 |
[Landry's syndrome and myocardial insufficiency in malignant diabetic acidosis; spectacular action of potassium chloride].
Topics: Diabetes Mellitus; Diabetic Ketoacidosis; Heart Failure; Myocardium; Paralysis; Potassium; Potassium | 1952 |
Insulin secretion is stimulated by ethanol extract of Anemarrhena asphodeloides in isolated islet of healthy Wistar and diabetic Goto-Kakizaki Rats.
Topics: Anemarrhena; Animals; Diabetes Mellitus; Electrophysiology; Ethanol; In Vitro Techniques; Insulin; I | 2004 |
A pancreatic islet-specific microRNA regulates insulin secretion.
Topics: Animals; Calcium Signaling; Cell Line; Cloning, Molecular; Diabetes Mellitus; Exocytosis; Gene Expre | 2004 |
MafA is a key regulator of glucose-stimulated insulin secretion.
Topics: Animals; Arginine; Cells, Cultured; Diabetes Mellitus; Female; Gene Expression Regulation; Gene Targ | 2005 |
Paralysis due to reduced serum potassium concentration during treatment of diabetic acidosis; report of case treated with 33 grams of potassium chloride intravenously.
Topics: Acidosis; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Potassium; Potassium Chloride | 1949 |
Diabetes and reactivity of isolated human saphenous vein.
Topics: Aged; Angiotensin II; Blood Vessels; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Hu | 1984 |
Intractable syncope.
Topics: Bradycardia; Diabetes Mellitus; Diagnosis, Differential; Electrocardiography; Female; Fludrocortison | 1981 |
Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Varia | 1996 |
Insulin-secreting activity of the traditional antidiabetic plant Viscum album (mistletoe).
Topics: 1-Methyl-3-isobutylxanthine; Alanine; Analysis of Variance; Animals; Cell Line; Diabetes Mellitus; G | 1999 |
Management of diabetic patients with low blood pH.
Topics: Adult; Bicarbonates; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Hydrogen-Ion Concentration; I | 1977 |
Influence of basal insulin and glucagon secretion on potassium and sodium metabolism. Studies with somatostatin in normal dogs and in normal and diabetic human beings.
Topics: Adult; Animals; Diabetes Mellitus; Dogs; Female; Glucagon; Humans; Insulin; Insulin Secretion; Male; | 1978 |
Peri-operative management of diabetes mellitus.
Topics: Diabetes Mellitus; Glucose; Humans; Insulin; Intraoperative Period; Postoperative Care; Potassium Ch | 1991 |
[Evaluation of the use of potassium salts in the treatment of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Diabetes Mellitus; Drug Evaluation; Female; Humans; Male; Middle Aged; Pota | 1974 |
[Remission phases in diabetes mellitus].
Topics: Acid-Base Equilibrium; Blood Glucose; Diabetes Mellitus; Diabetic Nephropathies; Follow-Up Studies; | 1973 |
Cirrhosis and diabetes. IV. Effect of potassium chloride administration on glucose and insulin metabolism.
Topics: Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Liver | 1970 |
[Potassium deficiency and potassium deficiency test in diabetics with treatment difficulties].
Topics: Carbohydrate Metabolism; Diabetes Mellitus; Humans; Potassium Chloride; Potassium Deficiency | 1965 |