potassium chloride has been researched along with Coronary Disease in 101 studies
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively." | 3.67 | [Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension]. ( Barnatskiĭ, VN; Korsunskiĭ, VN; Moiseev, AA; Stoliarov, VP; Vikhrov, NI, 1984) |
| " In our study we compared myocardial protection in isolated coronary bypass with a short period of ischemia using low dosage HTK and cold crystalloid cardioplegia." | 2.71 | Low-dose histidine-tryptophan-ketoglutarate solution for myocardial protection. ( Akay, T; Arslan, A; Aslamaci, S; Gultekin, B; Ozkan, S; Sezgin, A; Tasdelen, A; Uguz, E, 2005) |
| "Although some factors of gram-negative septicemia were identified in retrospect, others were masked by the clinical setting in which it occurred." | 1.27 | Cardioplegic solution: a contamination crisis. ( Baird, DK; Grant, AF; Hughes, CF; Leckie, BD, 1986) |
| " In contrast other solutions, such as the Bretschneider solution, which have extremes of electrolyre concentration, are associated with a complex dose-response relationship." | 1.26 | Protection of the ischemic myocardium. Volume-duration relationships and the efficacy of myocardial infusates. ( Braimbridge, MV; Hearse, DJ; Jynge, P, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 73 (72.28) | 18.7374 |
| 1990's | 21 (20.79) | 18.2507 |
| 2000's | 7 (6.93) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MANCINI, D | 1 |
| BUZZI, A | 1 |
| FRANCHELLA, JL | 1 |
| ZAGREANU, I | 1 |
| MANASIA, M | 1 |
| Norris, W | 1 |
| Kunzelman, KS | 1 |
| Bussell, S | 1 |
| Rohweder, L | 1 |
| Cochran, RP | 1 |
| Arslan, A | 1 |
| Sezgin, A | 1 |
| Gultekin, B | 1 |
| Ozkan, S | 1 |
| Akay, T | 1 |
| Uguz, E | 1 |
| Tasdelen, A | 1 |
| Aslamaci, S | 1 |
| Golbasi, I | 1 |
| Tasatargil, A | 1 |
| Aksoy, NH | 1 |
| Sadan, G | 1 |
| Karasu, E | 1 |
| Turkay, C | 1 |
| Bayezid, O | 1 |
| Stambulova, GG | 1 |
| Nikolaeva, SA | 1 |
| Bendikov, EA | 2 |
| Mitrofanov, VS | 2 |
| Korsunskiĭ, VN | 1 |
| Moiseev, AA | 1 |
| Barnatskiĭ, VN | 1 |
| Stoliarov, VP | 1 |
| Vikhrov, NI | 1 |
| Ginsburg, R | 1 |
| Bristow, MR | 1 |
| Davis, K | 1 |
| Dibiase, A | 1 |
| Billingham, ME | 1 |
| Shine, KI | 1 |
| Douglas, AM | 1 |
| Vouhé, PR | 1 |
| Hélias, J | 1 |
| Robert, P | 1 |
| Grondin, CM | 1 |
| Pivovarov, IuI | 1 |
| Kryzhanovskiĭ, GN | 1 |
| Heineman, FW | 1 |
| MacGregor, DC | 1 |
| Wilson, GJ | 2 |
| Ninomiya, J | 1 |
| Salerno, TA | 1 |
| Wasan, SM | 1 |
| Charrette, EJ | 1 |
| Turlapaty, PD | 1 |
| Altura, BM | 1 |
| Ettinger, PO | 1 |
| Moore, RJ | 1 |
| Calabro, J | 1 |
| Oldewurtel, HA | 1 |
| Regan, TJ | 1 |
| Noyez, L | 1 |
| van Son, JA | 1 |
| van der Werf, T | 1 |
| Knape, JT | 1 |
| Gimbrère, J | 1 |
| van Asten, WN | 1 |
| Lacquet, LK | 1 |
| Flameng, W | 1 |
| Lydrup, ML | 1 |
| Nilsson, BO | 1 |
| Miller, AA | 1 |
| Megson, IL | 1 |
| Gray, GA | 1 |
| Sunderdiek, U | 1 |
| Feindt, P | 1 |
| Gams, E | 1 |
| Demers, P | 1 |
| Elkouri, S | 1 |
| Sirois, MG | 1 |
| Cartier, R | 1 |
| Jones, JJ | 1 |
| Dietz, NJ | 1 |
| Heaps, CL | 1 |
| Parker, JL | 1 |
| Sturek, M | 1 |
| Jynge, P | 2 |
| Hearse, DJ | 5 |
| Braimbridge, MV | 2 |
| Matveĭkov, GP | 1 |
| Ziuzenkov, MV | 1 |
| So, CS | 1 |
| Oversohl, K | 1 |
| Lolley, DM | 1 |
| Ray, JF | 1 |
| Myers, WO | 1 |
| Sautter, RD | 1 |
| Tewksbury, DA | 1 |
| Conti, F | 1 |
| Fabbri, A | 1 |
| Tappainer, E | 1 |
| Ghidelli, L | 1 |
| Furlan, G | 1 |
| Besa, G | 1 |
| Senges, J | 1 |
| Brachmann, J | 1 |
| Pelzer, D | 1 |
| Mizutani, T | 1 |
| Kübler, W | 1 |
| Di Summa, M | 1 |
| Carletta, C | 1 |
| Morea, M | 1 |
| Nunnally, RL | 1 |
| Hollis, DP | 1 |
| Vanina, LV | 1 |
| Kretova, NE | 1 |
| Smirnova, AA | 1 |
| Glukhova, PA | 1 |
| Ebert, PA | 1 |
| Scott, WC | 1 |
| Shemin, RJ | 1 |
| Gaudiani, VA | 1 |
| Conkle, DM | 1 |
| Barg, IA | 1 |
| Lisnianskaia, RIa | 1 |
| Novikov, VT | 1 |
| Al'perovich, BR | 1 |
| Clark, RE | 1 |
| Ferguson, TB | 1 |
| West, PN | 1 |
| Shuchleib, RC | 1 |
| Henry, PD | 1 |
| Brodskiĭ, MD | 1 |
| Rossi, A | 1 |
| Ziacchi, V | 1 |
| Sigurd, B | 1 |
| Olesen, KH | 1 |
| Wennevold, A | 1 |
| Opie, LH | 1 |
| Todd, GJ | 1 |
| Tyers, GF | 1 |
| Leshchinskiĭ, LA | 1 |
| Shinkareva, IA | 1 |
| Stanley, AW | 1 |
| Moraski, RE | 1 |
| Russell, RO | 1 |
| Rogers, WJ | 1 |
| Mantle, JA | 1 |
| Kreisberg, RA | 1 |
| McDaniel, HG | 1 |
| Rackley, CE | 1 |
| Denchuk, NI | 1 |
| Uchida, Y | 1 |
| Martinez-Leon, J | 1 |
| Carbonell-Canti, C | 1 |
| Ortega-Serrano, J | 1 |
| Sargent, CA | 1 |
| Vesterqvist, O | 1 |
| McCullough, JR | 1 |
| Ogletree, ML | 1 |
| Grover, GJ | 1 |
| Mankad, PS | 1 |
| Chester, AH | 1 |
| Yacoub, MH | 1 |
| Liu, JJ | 1 |
| Gu, XH | 1 |
| Casley, DJ | 1 |
| Nayler, WG | 1 |
| Brunner, E | 1 |
| Tian, GH | 1 |
| Mainwood, GW | 1 |
| Biro, GP | 1 |
| Smith, KE | 1 |
| Butler, KW | 1 |
| Lawrence, D | 1 |
| Deslauriers, R | 1 |
| Jennings, RB | 1 |
| Murry, CE | 1 |
| Reimer, KA | 1 |
| Magovern, JA | 1 |
| Pae, WE | 1 |
| Waldhausen, JA | 1 |
| Murashita, T | 1 |
| Avkiran, M | 1 |
| Esumi, K | 1 |
| Nishida, M | 1 |
| Shaw, D | 1 |
| Smith, TW | 1 |
| Marsh, JD | 1 |
| Schnabel, PA | 1 |
| Richter, J | 1 |
| Gebhard, MM | 1 |
| Mall, G | 1 |
| Schmiedl, A | 1 |
| Clavien, HJ | 1 |
| Bretschneider, HJ | 2 |
| Sellke, FW | 1 |
| Quillen, JE | 1 |
| Brooks, LA | 1 |
| Harrison, DG | 1 |
| Andĕl, M | 1 |
| Táborský, J | 1 |
| Martínek, J | 1 |
| Kohout, M | 1 |
| Kocandrle, V | 1 |
| Slabochová, Z | 1 |
| Baker, JE | 1 |
| Boerboom, LE | 1 |
| Olinger, GN | 1 |
| Galinanes, M | 1 |
| Armiger, LC | 1 |
| Harland-Smith, SJ | 1 |
| Eagar, RL | 1 |
| Kwan, YW | 1 |
| Wadsworth, RM | 1 |
| Kane, KA | 1 |
| Sakurada, T | 1 |
| Kuribayashi, R | 1 |
| Sekine, S | 1 |
| Aida, H | 1 |
| Seki, K | 1 |
| Goto, Y | 1 |
| Shibata, Y | 1 |
| Meguro, A | 1 |
| Hayashi, R | 1 |
| Saito, S | 1 |
| Axford-Gatley, RA | 1 |
| Feindel, CM | 1 |
| Kempsford, RD | 1 |
| Stier, A | 1 |
| Finch, SA | 1 |
| Schäfer, H | 1 |
| Gebhardt, MM | 1 |
| Allen, BS | 3 |
| Okamoto, F | 2 |
| Buckberg, GD | 4 |
| Bugyi, H | 2 |
| Leaf, J | 3 |
| Schwaiger, M | 1 |
| Yeatman, L | 1 |
| Tillisch, J | 1 |
| Kawata, N | 1 |
| Messenger, J | 1 |
| Lee, C | 1 |
| Pelleg, A | 1 |
| Mitamura, H | 1 |
| Price, R | 1 |
| Kaplinsky, E | 1 |
| Menduke, H | 1 |
| Dreifus, LS | 1 |
| Michelson, EL | 1 |
| Gallandat Huet, RC | 1 |
| Karliczek, GF | 1 |
| van der Heide, JN | 1 |
| Brenken, U | 1 |
| Mooi, B | 1 |
| van der Broeke, JJ | 1 |
| Jenkins, I | 1 |
| de Geus, AF | 1 |
| Blake, K | 1 |
| Clusin, WT | 1 |
| Franz, MR | 1 |
| Smith, NA | 1 |
| Houston, MC | 1 |
| Johnston, PE | 1 |
| Stahl, LD | 1 |
| Aversano, T | 1 |
| Ambrosio, G | 1 |
| Becker, LC | 1 |
| Kuz'min, AI | 1 |
| Shul'zhenko, VS | 1 |
| Medvedev, OS | 1 |
| Kapel'ko, VI | 1 |
| Vinten-Johansen, J | 2 |
| Rosenkranz, ER | 2 |
| Hughes, CF | 1 |
| Grant, AF | 1 |
| Leckie, BD | 1 |
| Baird, DK | 1 |
| Sukhorukova, ES | 1 |
| Solov'ev, VV | 1 |
| Myers, CL | 1 |
| Weiss, SJ | 1 |
| Kirsh, MM | 1 |
| Shepard, BM | 1 |
| Shlafer, M | 1 |
| Onishchenko, NA | 1 |
| Lubiako, AA | 1 |
| Majid, PA | 1 |
| Sharma, B | 1 |
| Meeran, MK | 1 |
| Taylor, SH | 1 |
| Zil'berman, DB | 1 |
| Taĭkh, IaI | 1 |
| Krasheninikova, NG | 1 |
| Kozlova, LL | 1 |
| Kamenetskaia, IIa | 1 |
| Chechik, EA | 1 |
| Kaminskiĭ, VG | 1 |
| Kravtsov, VL | 1 |
| Aleksentseva, LN | 1 |
| Jacobs, E | 1 |
| Pringot, J | 1 |
| Hübner, G | 1 |
| Kaverina, NV | 1 |
| Rozonov, IuB | 1 |
| Kots, IaI | 1 |
| Pyzik, Z | 1 |
| Raffo, M | 1 |
| Biddau, C | 1 |
| Bina, M | 1 |
| Fonzo, R | 1 |
| Perpignano, G | 1 |
| Chessa, A | 1 |
| Cherchi, A | 1 |
| Dhurandhar, RW | 1 |
| Teasdale, SJ | 1 |
| Mahon, WA | 1 |
| Kaiser, W | 1 |
| Klepzig, H | 1 |
| Chernogorov, IA | 1 |
| Kozhevnikov, IuA | 1 |
| Voskanov, MA | 1 |
| Buiuklian, AM | 1 |
| Radzivil, VF | 1 |
| Fedyshin, PS | 1 |
| Furkalo, NK | 1 |
| Korkushko, OV | 1 |
| Hentzer, L | 1 |
| Persson, I | 1 |
| Busch, EW | 1 |
| Gercken, G | 1 |
| Edlich, RF | 2 |
| Quattlebaum, FW | 2 |
| Lillehei, CW | 2 |
| Halmos, PB | 1 |
| Patterson, GC | 1 |
| Wajszczuk, WJ | 1 |
| Cywinski, JK | 1 |
| Fabris, C | 1 |
| Ira, TS | 1 |
| Zinner, EN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Custodiol-HTK Solution as a Cardioplegic Agent- A Prospective Non-Inferiority Randomized Clinical Trial[NCT01681095] | Phase 2 | 110 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of participants with all-cause mortality AS reported in the Society of Thoracic Surgeons (STS) database after 30 days postoperative (NCT01681095)
Timeframe: 30 days post procedure
| Intervention | participants (Number) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 0 |
| Cold Blood Cardioplegia | 0 |
CK-MB measured 24 hours post-operatively (NCT01681095)
Timeframe: 24 hours post procedure
| Intervention | ng/mL (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 20 |
| Cold Blood Cardioplegia | 24 |
CK-MB measured 48 hours post-operatively (NCT01681095)
Timeframe: 48 hours post procedure
| Intervention | ng/mL (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 6.0 |
| Cold Blood Cardioplegia | 7.8 |
CK-MB measured pre-operatively (NCT01681095)
Timeframe: pre-operative
| Intervention | ng/mL (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 1.9 |
| Cold Blood Cardioplegia | 2.6 |
Number of participants with new or worsening of cardiac dysrhythmias (NCT01681095)
Timeframe: up to 36 hrs post surgery
| Intervention | participants (Number) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 24 |
| Cold Blood Cardioplegia | 30 |
Troponin-I measured 24 hours post-operative (NCT01681095)
Timeframe: 24 hours post procedure
| Intervention | ng/mL (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 5.7 |
| Cold Blood Cardioplegia | 7.8 |
Troponin-I measured 48 hours post-operative (NCT01681095)
Timeframe: 48 hours post procedure
| Intervention | ng/mL (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 3.0 |
| Cold Blood Cardioplegia | 4.8 |
Troponin-I measured pre-operatively (NCT01681095)
Timeframe: pre-operatively
| Intervention | ng/mL (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | .03 |
| Cold Blood Cardioplegia | .03 |
Number of participants with cardiovascular-related mortality AS reported in the Society of Thoracic Surgeons (STS) database after 30 days postoperative (NCT01681095)
Timeframe: 30 days post procedure
| Intervention | participants (Number) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 0 |
| Cold Blood Cardioplegia | 0 |
Creatine phosphokinase MB isoenzyme (CK-MB) difference from baseline 7 hours post surgery (NCT01681095)
Timeframe: Baseline and 7 hours post surgery
| Intervention | ng/mL (Median) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 18.8 |
| Cold Blood Cardioplegia | 22.2 |
Troponin I values, difference from baseline 7 hours post surgery (NCT01681095)
Timeframe: Baseline and 7 hours post surgery
| Intervention | ng/mL (Median) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 9.65 |
| Cold Blood Cardioplegia | 10.15 |
LV ejection fraction by TTE, difference from baseline at 24 hours post surgery (NCT01681095)
Timeframe: Baseline and 24 hours post surgery
| Intervention | % LV volume (Mean) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | -0.06 |
| Cold Blood Cardioplegia | 1.9 |
Total time in minutes on any vasopressor or inotropic agent, including norepinephrine, epinephrine, vasopressin, milrinone, dobutamine, dopamine and/or neo-synephrine (NCT01681095)
Timeframe: up to 36 hours post procedure
| Intervention | minutes (Median) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 340 |
| Cold Blood Cardioplegia | 582 |
Duration of stay in ICU, from ICU admission to ICU discharge (NCT01681095)
Timeframe: up to 100 days after admission
| Intervention | days (Median) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 3 |
| Cold Blood Cardioplegia | 3 |
Number or participants fulfilling at least two of the following 3 criteria: (1) CK-MB of 100 ug/L or more and/or troponin-I of 3.0 ug/L or more, (2) appearance of new postoperative Q waves on the EKG of more than 0.03 seconds, and (3) a new hypokinetic or akinetic area in the left or right ventricle by echocardiography. (NCT01681095)
Timeframe: up to 36 hours post procedure
| Intervention | participants (Number) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 0 |
| Cold Blood Cardioplegia | 0 |
Number of patients receiving vasopressor or inotropic infusion for greater than 20 minutes in the operating room, including norepinephrine, epinephrine, vasopressin, milrinone, dobutamine, dopamine and/or neo-synephrine. (NCT01681095)
Timeframe: during operative procedure
| Intervention | participants (Number) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 47 |
| Cold Blood Cardioplegia | 43 |
time in hours from intubation to extubation, with intervening transport to the cardiac critical care unit. (NCT01681095)
Timeframe: up to 36 hours post procedure
| Intervention | hours (Median) |
|---|---|
| Cardioplegia: Custodiol HTK Solution | 10.5 |
| Cold Blood Cardioplegia | 11.4 |
4 reviews available for potassium chloride and Coronary Disease
| Article | Year |
|---|---|
Metabolism of free fatty acids, glucose and catecholamines in acute myocardial infarction. Relation to myocardial ischemia and infarct size.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Fatty Acids | 1975 |
Essential hypertension: new insights and controversies in treatment with diuretics.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Dose-Response Relat | 1986 |
[Pharmacological tests in the diagnosis of ischemic heart disease].
Topics: Atropine; Coronary Disease; Dipyridamole; Ergonovine; Glucose; Heart; Humans; Isoproterenol; Nitrogl | 1985 |
Electron microscopic investigation of cardioplegia. Electron microscopy of various forms of cardiac arrest in correlation with myocardial function.
Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Citrates; Coronary Disease; Disease Models, Animal; D | 1971 |
6 trials available for potassium chloride and Coronary Disease
| Article | Year |
|---|---|
Potassium supplementation, diet vs pills: a randomized trial in postoperative cardiac surgery patients.
Topics: Administration, Oral; Aged; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Disease; D | 2004 |
Low-dose histidine-tryptophan-ketoglutarate solution for myocardial protection.
Topics: Adult; Aged; Cardioplegic Solutions; Coronary Artery Bypass; Coronary Disease; Creatine Kinase; Fema | 2005 |
Retrograde versus antegrade delivery of cardioplegic solution in myocardial revascularization. A clinical trial in patients with three-vessel coronary artery disease who underwent myocardial revascularization with extensive use of the internal mammary art
Topics: Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Contraindications; Coronary Disease; Female; | 1993 |
Aortocoronary bypass grafting: a comparison of HTK cardioplegia vs. intermittent aortic cross-clamping.
Topics: Aged; Cardioplegic Solutions; Coronary Artery Bypass; Coronary Disease; Electrocardiography; Female; | 2000 |
The supra-additive natriuretic effect addition of bendroflumethiazide and bumetanide in congestive heart failure. Permutation trial tests in patients in long-term treatment with bumetanide.
Topics: Adult; Bendroflumethiazide; Benzoates; Butylamines; Chlorides; Clinical Trials as Topic; Coronary Di | 1975 |
Clinical effect of Bretschneider-HTK and St. Thomas cardioplegia on hemodynamic performance after bypass measured using an automatic datalogging database system.
Topics: Bicarbonates; Calcium Chloride; Clinical Trials as Topic; Computers; Coronary Artery Bypass; Coronar | 1988 |
91 other studies available for potassium chloride and Coronary Disease
| Article | Year |
|---|---|
[Action of potassium chloride on ventricular repolarization].
Topics: Coronary Disease; Electrocardiography; Humans; Potassium; Potassium Chloride | 1960 |
[OBSERVATIONS ON THE POTASSIUM CHLORIDE TEST IN THE ELECTROCARDIOGRAPHIC DIAGNOSIS OF CORONARY INSUFFICIENCY].
Topics: Chlorides; Coronary Artery Disease; Coronary Disease; Electrocardiography; Pharmacology; Potassium; | 1964 |
A functional and histopathological comparison of proximal and distal saphenous vein contractility and morphology.
Topics: Aged; Coronary Artery Bypass; Coronary Disease; Female; Humans; In Vitro Techniques; Male; Middle Ag | 2005 |
[The post-tachycardial syndrome].
Topics: Adult; Coronary Disease; Electrocardiography; Humans; Hypokalemia; Male; Potassium Chloride; Tachyca | 1966 |
[Coronary insufficiency and myocardial necroses caused by potassium chloride injection into the lateral ventricles of the cat brain].
Topics: Animals; Brain Injuries; Cardiomyopathies; Cats; Cerebral Ventricles; Coronary Disease; Electrocardi | 1966 |
[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension].
Topics: Bicarbonates; Coronary Disease; Humans; Hypertension; Injections, Intravenous; Potassium; Potassium | 1984 |
Quantitative pharmacologic responses of normal and atherosclerotic isolated human epicardial coronary arteries.
Topics: Calcium; Carbachol; Coronary Disease; Coronary Vessels; Ergonovine; Histamine; Humans; In Vitro Tech | 1984 |
Low calcium reperfusion of ischemic myocardium.
Topics: Adenosine Triphosphate; Animals; Calcium; Coronary Disease; Creatine; Electric Stimulation; Myocardi | 1983 |
Myocardial protection through cold cardioplegia with potassium or diltiazem. Experimental evidence that diltiazem provides better protection even when coronary flow is impaired by a critical stenosis.
Topics: Animals; Benzazepines; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Heart Arrest, Induce | 1982 |
[Effect of hyperactivation of the anterior amygdaloid nucleus on heart work in altered reactivity].
Topics: Amygdala; Animals; Coronary Disease; Coronary Vessels; Epinephrine; Heart; Heart Rate; Ligation; Pot | 1982 |
Regional and transmural myocardial temperature distribution in cold chemical cardioplegia: significance of critical coronary arterial stenosis.
Topics: Animals; Body Temperature; Cardiopulmonary Bypass; Coronary Disease; Dogs; Heart; Heart Arrest, Indu | 1981 |
Glucose substrate in myocardial protection.
Topics: Biopsy; Cardiopulmonary Bypass; Coronary Disease; Glucose; Glucose Solution, Hypertonic; Glycogen; H | 1980 |
Magnesium deficiency produces spasms of coronary arteries: relationship to etiology of sudden death ischemic heart disease.
Topics: Acetylcholine; Angiotensin II; Animals; Calcium; Coronary Disease; Coronary Vessels; Death, Sudden; | 1980 |
Ventricular tachyarrhythmias in regional myocardial hyperkalemia: efficacy of three antiarrhythmic agents.
Topics: Animals; Coronary Disease; Disease Models, Animal; Dogs; Electrocardiography; Heart Conduction Syste | 1980 |
Acute and long-term effects of 17 beta-oestradiol on agonist-stimulated force in rat tail artery.
Topics: Animals; Arteries; Cocaine; Coronary Disease; Enzyme Inhibitors; Estradiol; Female; Humans; In Vitro | 1996 |
Inducible nitric oxide synthase-derived superoxide contributes to hypereactivity in small mesenteric arteries from a rat model of chronic heart failure.
Topics: Animals; Arginine; Coronary Disease; Dose-Response Relationship, Drug; Endothelium; Heart Failure; I | 2000 |
Coronary artery endothelial dysfunction after ischemia-reperfusion and acute untreated rejection in a canine heterotopic heart transplantation model.
Topics: Animals; Coronary Disease; Dogs; Endothelium, Vascular; Female; Graft Rejection; GTP-Binding Protein | 2001 |
Calcium buffering in coronary smooth muscle after chronic occlusion and exercise training.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Buffers; Caffeine; Calcium; Cells, Culture | 2001 |
Protection of the ischemic myocardium. Volume-duration relationships and the efficacy of myocardial infusates.
Topics: Animals; Calcium Chloride; Coronary Disease; Drug Evaluation, Preclinical; Heart Arrest, Induced; Hy | 1978 |
[Polarizing mixtures in emergency cardiology].
Topics: Adult; Aged; Coronary Disease; Drug Combinations; Drug Evaluation; Emergencies; Female; Fibrinolysin | 1976 |
The clinical significance of the potassium stress ECG.
Topics: Cardiomegaly; Coronary Disease; Electrocardiography; Evaluation Studies as Topic; Humans; Potassium | 1978 |
Importance of preoperative myocardial glycogen levels in human cardiac preservation. Preliminary report.
Topics: Aorta; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Constriction; Coronary Artery Bypass; Coro | 1979 |
[Progress in myocardial protection during anoxic arrest. Combination of deep local hypothermia with coronary perfusion with cold cardioplegic solutions].
Topics: Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Coronary Vessels; Glucose; Heart Arres | 1979 |
Effects of some components of ischemia on electrical activity and reentry in the canine ventricular conducting system.
Topics: Acidosis; Action Potentials; Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Coronary Dis | 1979 |
[Myocardial protection from cardioplegic and hypothermia during aortic cross-clamping (author's ttrans)].
Topics: Adenosine Triphosphate; Aorta; Calcium Chloride; Cardiac Surgical Procedures; Constriction; Coronary | 1979 |
Adenosine triphosphate compartmentation in living hearts: a phosphorus nuclear magnetic resonance saturation transfer study.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Creatine Kinase; Heart; Magnetic Resonance Spectr | 1979 |
[Differential diagnosis of climacteric cardiopathy and ischemic heart disease].
Topics: Cardiomyopathies; Climacteric; Coronary Disease; Diagnosis, Differential; Electrocardiography; Exerc | 1979 |
Aspects of myocardial protection.
Topics: Aorta; Cardiac Surgical Procedures; Cold Temperature; Constriction; Coronary Disease; Heart Arrest, | 1978 |
Limits of myocardial protection with potassium cardioplegia.
Topics: Animals; Aorta; Cardiopulmonary Bypass; Constriction; Coronary Disease; Dogs; Heart Arrest, Induced; | 1978 |
Myocardial protection during ischemic cardiac arrest. A possible hazard with calcium-free cardioplegic infusates.
Topics: Animals; Aorta; Calcium; Cardiopulmonary Bypass; Coronary Circulation; Coronary Disease; Coronary Ve | 1977 |
[Differential diagnosis of ischemic heart disease and cardialgia by means of pharmacological tests in the polyclinical practice].
Topics: Adult; Ambulatory Care; Anti-Arrhythmia Agents; Coronary Disease; Diagnosis, Differential; Electroca | 1977 |
Pharmacological preservation of the ischemic heart.
Topics: Animals; Calcium; Calcium Chloride; Cardiopulmonary Bypass; Coronary Disease; Dogs; Female; Heart Fa | 1977 |
[Simultaneous inderal-potassium test].
Topics: Adult; Aged; Coronary Disease; Diagnosis, Differential; Electrocardiography; Female; Heart Diseases; | 1977 |
[The oral potassium loading test in the evaluation of the isolated T-wave anomaly].
Topics: Administration, Oral; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Diagnostic Er | 1977 |
Amelioration of the effects of ischemic cardiac arrest by the intracoronary administration of cardioplegic solutions.
Topics: Animals; Cardiac Output; Cardiopulmonary Bypass; Citrates; Coronary Circulation; Coronary Disease; C | 1975 |
[Certain methods of drug therapy of ischemic heart disease].
Topics: Anabolic Agents; Coronary Disease; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Gl | 1975 |
Effects of glucose-insulin-potassium on myocardial substrate availability and utilization in stable coronary artery disease. Studies on myocardial carbohydrate, lipid and oxygen arterial-coronary sinus differences in patients with coronary artery disease.
Topics: Adult; Aged; Blood Glucose; Coronary Disease; Fatty Acids, Nonesterified; Glucose; Humans; Infusions | 1975 |
[Potassium chloride test-load for differentiation of electrocardiographic indicators of repolarization disorders in coronary insufficiency].
Topics: Adult; Aged; Coronary Disease; Electrocardiography; Female; Heart; Humans; Male; Middle Aged; Potass | 1975 |
Tachypnea after stimulation of afferent cardiac sympathetic nerve fibers.
Topics: Action Potentials; Animals; Coronary Disease; Coronary Vessels; Dogs; Electric Stimulation; Electrop | 1976 |
Myocardial protection by retrograde cardioplegic perfusion in the presence of acute coronary artery obstruction. An experimental study.
Topics: Animals; Aorta; Blood Pressure; Body Water; Cardioplegic Solutions; Cardiopulmonary Bypass; Contrast | 1992 |
Effect of the phospholipase A2 inhibitors quinacrine and 7,7-dimethyleicosadienoic acid in isolated globally ischemic rat hearts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Ischaemic endothelial dysfunction after single or multidose cardioplegia.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Circulation; Coronary Dise | 1992 |
Reoxygenation, but neither hypoxia nor intermittent ischemia, increases [125I]endothelin-1 binding to rat cardiac membranes.
Topics: Acidosis; Aerobiosis; Animals; Cell Hypoxia; Coronary Disease; Endothelins; In Vitro Techniques; Iod | 1990 |
A nonparametric estimator of the shift effect for repeated observations.
Topics: Animals; Atrioventricular Node; Cardioplegic Solutions; Coronary Disease; Dogs; Glucose; In Vitro Te | 1991 |
The effect of high buffer cardioplegia and secondary cardioplegia on cardiac preservation and postischemic functional recovery: a 31P NMR and functional study in Langendorff perfused pig hearts.
Topics: Adenosine Triphosphate; Animals; Bicarbonates; Buffers; Calcium; Calcium Chloride; Cardioplegic Solu | 1991 |
Energy metabolism in preconditioned and control myocardium: effect of total ischemia.
Topics: Adenine Nucleotides; Animals; Coronary Disease; Dogs; Energy Metabolism; Female; Glycogen; Glycolysi | 1991 |
Age-related changes in the efficacy of crystalloid cardioplegia.
Topics: Aging; Animals; Aorta; Bicarbonates; Calcium Chloride; Coronary Disease; Heart Arrest, Induced; Hemo | 1991 |
Effects of diltiazem as an additive to St Thomas's Hospital cardioplegic solution in isolated neonatal and adult rabbit hearts.
Topics: Aging; Animals; Bicarbonates; Calcium Chloride; Coronary Disease; Diltiazem; Dose-Response Relations | 1991 |
NADH measurements in adult rat myocytes during simulated ischemia.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cell Movement; Coronary Disease; Cyanides; Deo | 1991 |
Ultrastructural effects induced by global ischaemia on the AV node compared with the working myocardium. A qualitative and morphometric investigation on the canine heart.
Topics: Animals; Atrioventricular Node; Cardioplegic Solutions; Coronary Disease; Dogs; Glucose; Heart Condu | 1990 |
Endothelial modulation of the coronary vasculature in vessels perfused via mature collaterals.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Calcimycin; Collateral Circulation; Coronary Circulat | 1990 |
Cardioprotective conditioning with glucose and insulin prior to cardiac surgery involving ischaemic cold arrest.
Topics: Adult; Catheterization, Central Venous; Coronary Artery Bypass; Coronary Disease; Glucose; Heart Arr | 1990 |
Cardioplegia-induced damage to ischemic immature myocardium is independent of oxygen availability.
Topics: Animals; Bicarbonates; Buffers; Calcium Chloride; Cardiac Output; Cardioplegic Solutions; Coronary C | 1990 |
Assessment of ischemic injury and protective interventions: the Langendorff versus the working rat heart preparation.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Disease; Heart; Magnesium; | 1990 |
Induction of fine structural alteration in cardiac Purkinje cells by ischaemic metabolites depends on oxygen tension.
Topics: Animals; Coronary Disease; Dogs; Heart Conduction System; Hydrogen-Ion Concentration; Microscopy, El | 1990 |
Effects of neuropeptide Y and calcitonin gene-related peptide on sheep coronary artery rings under oxygenated, hypoxic and simulated myocardial ischaemic conditions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcitonin Gene-Related | 1990 |
[Clinical study on the use of retrograde cardioplegia with St. Thomas' Hospital solution].
Topics: Adult; Aorta; Aortic Valve; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Coronary Artery | 1990 |
Comparison of blood-based and asanguineous cardioplegic solutions administered at 4 degrees C. An ultrastructural morphometric study in the dog.
Topics: Animals; Aorta; Blood; Cardioplegic Solutions; Cold Temperature; Constriction; Coronary Disease; Dog | 1990 |
Protection of the immature myocardium during global ischemia. A comparison of four clinical cardioplegic solutions in the rabbit heart.
Topics: Acetates; Animals; Animals, Newborn; Bicarbonates; Calcium Chloride; Cardiac Output; Cardioplegic So | 1989 |
31P-NMR spectroscopy of phosphate compartmentation during ischaemia in hearts protected by cardioplegic treatment.
Topics: Animals; Cardioplegic Solutions; Coronary Disease; Dogs; Glucose; Hydrogen-Ion Concentration; Magnet | 1989 |
Reperfusion conditions: critical importance of total ventricular decompression during regional reperfusion.
Topics: Animals; Aspartic Acid; Calcium; Cardiac Catheterization; Coronary Circulation; Coronary Disease; Di | 1986 |
Early recovery of regional wall motion in patients following surgical revascularization after eight hours of acute coronary occlusion.
Topics: Aspartic Acid; Citrates; Citric Acid; Coronary Circulation; Coronary Disease; Glucose; Glutamates; G | 1986 |
Extracellular potassium ion dynamics and ventricular arrhythmias in the canine heart.
Topics: Animals; Coronary Disease; Dogs; Electrocardiography; Extracellular Space; Female; Male; Myocardial | 1989 |
Mechanism of depolarization in the ischaemic dog heart: discrepancy between T-Q potentials and potassium accumulation.
Topics: Action Potentials; Animals; Calcium Chloride; Coronary Disease; Dogs; Electrocardiography; Heart; In | 1988 |
Effect of repeated episodes of drug-induced ventricular dyskinesia on subsequent regional function in the dog: comparison with myocardial stunning produced by repeated coronary occlusions.
Topics: Animals; Cardiac Catheterization; Cardiomyopathies; Coronary Circulation; Coronary Disease; Dogs; Dy | 1987 |
[Relationship between adenine nucleotide breakdown and catecholamine losses in myocardial ischemia and the recovery of contractile function during reperfusion].
Topics: Adenine Nucleotides; Animals; Catecholamines; Cesium; Chlorides; Coronary Disease; Desipramine; Guin | 1987 |
Metabolic and histochemical benefits of regional blood cardioplegic reperfusion without cardiopulmonary bypass.
Topics: Animals; Aspartic Acid; Blood; Calcium; Cardiopulmonary Bypass; Coronary Circulation; Coronary Disea | 1986 |
High oxygen requirements of dyskinetic cardiac muscle.
Topics: Animals; Blood; Calcium; Coronary Circulation; Coronary Disease; Dogs; Heart Arrest, Induced; Moveme | 1986 |
Cardioplegic solution: a contamination crisis.
Topics: Acute Disease; Aged; Aneurysm, Infected; Blood Coagulation Tests; Cardiac Tamponade; Coronary Diseas | 1986 |
Effects of supplementing hypothermic crystalloid cardioplegic solution with catalase, superoxide dismutase, allopurinol, or deferoxamine on functional recovery of globally ischemic and reperfused isolated hearts.
Topics: Allopurinol; Animals; Bicarbonates; Blood Pressure; Calcium Chloride; Catalase; Coronary Circulation | 1986 |
[Anti-ischemic protection of the myocardium by cardioplegic solutions].
Topics: Animals; Coronary Disease; Dogs; Heart Arrest, Induced; Magnesium; Magnesium Chloride; Potassium Chl | 1985 |
Insulin and glucose in the treatment of heart-failure.
Topics: Administration, Oral; Aged; Blood Glucose; Blood Pressure; Cardiac Output; Coronary Disease; Drug Sy | 1972 |
[Experience in the use of a polarizing mixture in the acute period of myocardial infarct by a specialized first aid emergency center].
Topics: Acute Kidney Injury; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Disease; Emergenci | 1968 |
[Potassium chloride test in evaluating electrocardiograms in aviation medical expertise].
Topics: Adult; Aerospace Medicine; Coronary Disease; Electrocardiography; Humans; Middle Aged; Potassium Chl | 1972 |
Gastric ulcers due to the intake of potassium chloride.
Topics: Adult; Coronary Disease; Female; Humans; Male; Obesity; Potassium Chloride; Radiography; Stomach Ulc | 1973 |
[New data on the mechanism of the action of nitrites on coronary circulation].
Topics: Angina Pectoris; Animals; Blood Circulation; Cats; Central Nervous System; Coronary Disease; Coronar | 1967 |
[Use of potassium chloride in cardiovascular diseases].
Topics: Administration, Oral; Adult; Arrhythmias, Cardiac; Coronary Disease; Dyspepsia; Female; Gastrointest | 1970 |
[Clinical evaluation of the potassium chloride and Gynergen tests for the differentiation of the changes of heart repolarization in the electrocardiogram].
Topics: Adolescent; Adult; Aged; Coronary Disease; Diagnosis, Differential; Electrocardiography; Ergonovine; | 1969 |
[On the action of oral potassium on the electrocardiogram during exercise in normal subjects, hypersympathotonic subjects and patients with coronary disease or pericarditis].
Topics: Adolescent; Adult; Coronary Disease; Dysautonomia, Familial; Electrocardiography; Female; Heart; Hum | 1970 |
Bretylium tosylate in the management of refractory ventricular fibrillation.
Topics: Adult; Age Factors; Aged; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Bretyl | 1971 |
[Can the digitalis induced changes of the stress electrocardiogram be prevented by potassium administration?].
Topics: Adult; Coronary Disease; Diagnosis, Differential; Digitalis Glycosides; Electrocardiography; Humans; | 1967 |
[Treatment of stenocardia with potassium chloride in conjunction with substances increasing cellular permeability].
Topics: Aminophylline; Angina Pectoris; Cell Membrane Permeability; Coronary Disease; Glucose; Humans; Insul | 1967 |
[Treatment of arrhythmias].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Diet, Sodium-Restricted; Humans; Hyp | 1967 |
Small bowel ulceration. An evaluation of thiazide therapy.
Topics: Aged; Bendroflumethiazide; Biphenyl Compounds; Burns, Chemical; Coronary Disease; Delayed-Action Pre | 1968 |
[Degradation of purine nucleotides and carbohydrates in the KC1-arrested rabbit heart and ischemic dog heart].
Topics: Adenine; Adenine Nucleotides; Animals; Coronary Disease; Dogs; Glycogen; Heart Arrest; Hypoxanthines | 1969 |
Effect of norepinephrine upon coronary collateral blood flow after experimental coronary artery occlusion.
Topics: Animals; Blood Pressure; Cardiac Output; Collateral Circulation; Coloring Agents; Coronary Disease; | 1969 |
Measurement of coronary collateral blood flow using radioactive rubidium chloride.
Topics: Animals; Blood Flow Velocity; Cardiac Output; Catheterization; Collateral Circulation; Coronary Dise | 1969 |
Effect of atrial fibrillation on cardiac output.
Topics: Adult; Aged; Atrial Fibrillation; Cardiac Output; Coronary Disease; Digitalis Glycosides; Electric C | 1965 |
Observations on D. C. and very low frequency components of the electrocardiogram.
Topics: Animals; Coronary Disease; Dogs; Electrocardiography; Ischemia; Potassium Chloride; Rabbits; Sodium | 1966 |
[Contribution to the study of polarizing therapy in anoxic myocardial diseases].
Topics: Coronary Disease; Humans; In Vitro Techniques; Infusions, Parenteral; Potassium Chloride | 1966 |
Small bowel ulceration.
Topics: Aged; Coronary Disease; Diagnosis, Differential; Female; Humans; Hydrochlorothiazide; Ileum; Intesti | 1966 |