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potassium chloride and Cerebral Ischemia

potassium chloride has been researched along with Cerebral Ischemia in 40 studies

Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.

Research Excerpts

ExcerptRelevanceReference
"Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated."7.68Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992)
" Rats which survived hypoglycemia by insulin, hypoxia by 10% O2, or ischemia by carotid ligation and hypotension to 40 mm Hg, evidenced no changes in cerebrospinal fluid (CSF) uridine."7.68Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. ( Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA, 1990)
"Effect of minaprine on hypoxia- or hypoxia/hypoglycemia (ischemia)-induced impairment of 2-deoxyglucose (2DG) uptake by rat hippocampal slices was evaluated."3.68Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia. ( Kodama, K; Shibata, S; Ueki, S, 1992)
" Rats which survived hypoglycemia by insulin, hypoxia by 10% O2, or ischemia by carotid ligation and hypotension to 40 mm Hg, evidenced no changes in cerebrospinal fluid (CSF) uridine."3.68Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. ( Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA, 1990)
"In conclusion, focal cerebral ischemia and reperfusion impaired vasoconstrictor responses in remote brain arteries of rats by a mechanism involving free radicals."1.36Decreased vasoconstrictor responses in remote cerebral arteries after focal brain ischemia and reperfusion in the rat, in vitro. ( Albert, M; Benedek, A; Hársing, LG; Kovács, A; Móricz, K; Szénási, G, 2010)
"These data suggest that acute cerebral ischemia may specifically disturb cardiac function and calcium homeostasis, which are related to increase of Ca(v)1."1.36Cerebral ischemia elicits aberration in myocardium contractile function and intracellular calcium handling. ( Ai, J; Hang, P; Li, J; Lu, Y; Sun, L; Wang, N; Wu, W; Yang, B; Zhang, R; Zhang, T, 2010)
"Cerebral ischemic model was made by middle cerebral artery occlusion (MCAO)."1.35Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia. ( Du, J; Pan, G; Sun, L; Wang, L; Yang, B; Zhang, G; Zhang, Y, 2008)
"Status epilepticus and cerebral ischemia stimulate persistent neurogenesis in the adult brain, but both conditions cause neuronal damage."1.33Induced spreading depression activates persistent neurogenesis in the subventricular zone, generating cells with markers for divided and early committed neurons in the caudate putamen and cortex. ( Kikuchi, H; Miyamoto, S; Nagata, I; Nakajo, Y; Nakano, Y; Tohnai, N; Xue, JH; Yanamoto, H, 2005)
"Focal brain infarcts are surrounded by extended perilesional zones that comprise the partially ischemic penumbra but also completely non-ischemic cortex of the remote ipsilateral hemisphere."1.32Transcriptional response to circumscribed cortical brain ischemia: spatiotemporal patterns in ischemic vs. remote non-ischemic cortex. ( Jander, S; Küry, P; Schroeter, M, 2004)
"When hyperglycemia was induced 30 minutes before SD, c-fos induction was enhanced by 388% and COX-2 expression by 53%, whereas the induction of PKCdelta and HO-1 was reduced to 54% and 51%, respectively."1.30Spreading depression-induced gene expression is regulated by plasma glucose. ( Chan, PH; Koistinaho, J; Pasonen, S; Yrjänheikki, J, 1999)
"The histamine output was markedly reduced by intraperitoneal injection of alpha-fluoromethylhistidine (100 mg/kg), an irreversible inhibitor of histidine decarboxylase, or (R)-alpha-methylhistamine (5 mg/kg), a potent and specific H3-receptor agonist."1.28Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion. ( Adachi, N; Itoh, Y; Oishi, R; Saeki, K, 1992)
"In dogs global cerebral ischemia was produced by clamping reversibly the left subclavian and brachiocephalic arteries, supplying the head."1.27Measurement of ischemic changes in cerebral blood flow by the hydrogen clearance technique and brain cortical temperature. Influence of flunarizine. ( Edmonds, HL; Marrannes, R; Melis, W; Van Loon, J; Wauquier, A, 1986)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.50)18.7374
1990's12 (30.00)18.2507
2000's17 (42.50)29.6817
2010's7 (17.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Oğuz, S1
Aşgün, HF1
Büyük, B1
Sugimoto, K1
Nomura, S1
Shirao, S1
Inoue, T1
Ishihara, H1
Kawano, R1
Kawano, A1
Oka, F1
Suehiro, E1
Sadahiro, H1
Shinoyama, M1
Oku, T1
Maruta, Y1
Hirayama, Y1
Hiyoshi, K1
Kiyohira, M1
Yoneda, H1
Okazaki, K1
Dreier, JP1
Suzuki, M1
Inui, T1
Alessandri, B1
Heimann, A1
Nishimura, F1
Frauenknecht, K1
Sommer, C1
Kempski, O1
Sun, L2
Du, J1
Zhang, G1
Zhang, Y1
Pan, G1
Wang, L1
Yang, B2
van Rensburg, R1
Errington, DR1
Ennaceur, A1
Lees, G1
Obrenovitch, TP2
Chazot, PL1
Farkas, E1
Institóris, Á1
Bari, F1
Luccini, E1
Romei, C1
Di Prisco, S1
Raiteri, M1
Raiteri, L1
Kovács, A1
Móricz, K1
Albert, M1
Benedek, A1
Hársing, LG1
Szénási, G1
Ai, J1
Wang, N1
Zhang, R1
Li, J1
Zhang, T1
Wu, W1
Hang, P1
Lu, Y1
Carter, RE1
Aiba, I1
Dietz, RM1
Sheline, CT1
Shuttleworth, CW1
Mayevsky, A1
Barbiro-Michaely, E1
Ligeti, L1
MacLaughlin, AC1
Wiggins, AK1
Shen, PJ1
Gundlach, AL1
Christensen, T1
Bruhn, T1
Diemer, NH1
Selman, WR1
Lust, WD1
Pundik, S1
Zhou, Y1
Ratcheson, RA1
Küry, P1
Schroeter, M1
Jander, S1
Bancila, V1
Nikonenko, I1
Dunant, Y1
Bloc, A1
Persson, M1
Brantefjord, M1
Hansson, E1
Rönnbäck, L1
Yanamoto, H2
Miyamoto, S1
Tohnai, N1
Nagata, I2
Xue, JH1
Nakano, Y1
Nakajo, Y1
Kikuchi, H2
Kofler, J1
Otsuka, T1
Zhang, Z2
Noppens, R1
Grafe, MR1
Koh, DW1
Dawson, VL1
de Murcia, JM1
Hurn, PD1
Traystman, RJ1
Shirasaki, Y1
Kanazawa, Y1
Morishima, Y1
Makino, M1
Muramatsu, H1
Welsh, FA1
Karikó, K1
Han, F1
Shioda, N1
Moriguchi, S1
Qin, ZH1
Fukunaga, K1
Chiou, GC1
Hong, SJ1
Yamashima, T1
Takita, M1
Akaike, S1
Hirano, M1
Miyakawa, A1
Miyazawa, A1
Kudo, Y1
Yoshioka, T1
Calò, G1
Sbrenna, S1
Bianchi, C1
Beani, L1
Marrelli, SP1
Johnson, TD1
Khorovets, A1
Childres, WF1
Bryan, RM1
Koistinaho, J2
Pasonen, S1
Yrjänheikki, J1
Chan, PH1
Dijkhuizen, RM1
Beekwilder, JP1
van der Worp, HB1
Berkelbach van der Sprenkel, JW1
Tulleken, KA1
Nicolay, K1
Mizuta, I1
Xue, J1
Kurkinen, K1
Keinänen, R1
Li, W1
Holmin, S1
von Gertten, C1
Sandberg-Nordqvist, AC1
Lendahl, U1
Mathiesen, T1
Kodama, K1
Shibata, S1
Ueki, S1
Juurlink, BH1
Chen, Y1
Hertz, L1
Adachi, N1
Itoh, Y1
Oishi, R1
Saeki, K1
Katusić, ZS1
Michenfelder, JD1
Milde, JH1
Boakye, P1
White, EJ1
Clark, JB1
Mueller, RA1
McCown, TJ1
Hunt, RD1
Lundberg, C1
Breese, GR1
Marrannes, R1
Edmonds, HL1
Wauquier, A1
Melis, W1
Van Loon, J1
Yasuda, H1
Izumi, N1
Nakanishi, M1
Anami, K1
Maruyama, Y1
Wendling, WW1
Harakal, C1

Trials

1 trial available for potassium chloride and Cerebral Ischemia

ArticleYear
Cilostazol decreases duration of spreading depolarization and spreading ischemia after aneurysmal subarachnoid hemorrhage.
    Annals of neurology, 2018, Volume: 84, Issue:6

    Topics: Aged; Animals; Brain Ischemia; Cerebrovascular Circulation; Cilostazol; Cortical Spreading Depressio

2018

Other Studies

39 other studies available for potassium chloride and Cerebral Ischemia

ArticleYear
Effectiveness of Brain Protection With Histidine-Tryptophan-Ketoglutarate Solutions.
    The heart surgery forum, 2020, Jul-22, Volume: 23, Issue:4

    Topics: Animals; Biopsy; Brain; Brain Ischemia; Cardioplegic Solutions; Disease Models, Animal; Glucose; Mal

2020
Neuroprotective effect of ceftriaxone on the penumbra in a rat venous ischemia model.
    Neuroscience, 2013, Jul-09, Volume: 242

    Topics: Animals; Anti-Bacterial Agents; Brain Ischemia; Ceftriaxone; Cerebral Infarction; Cortical Spreading

2013
Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2008, Volume: 22, Issue:1-4

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Brain Ischemia; Caffeine; Calcium; Calcium Channel

2008
A new model for the study of high-K(+)-induced preconditioning in cultured neurones: role of N-methyl-d-aspartate and alpha7-nicotinic acetylcholine receptors.
    Journal of neuroscience methods, 2009, Mar-15, Volume: 177, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Brain Ischemia; Calcium-Calmodulin-Dependen

2009
Effects of early aging and cerebral hypoperfusion on spreading depression in rats.
    Neurobiology of aging, 2011, Volume: 32, Issue:9

    Topics: Aging; Animals; Brain Ischemia; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Cor

2011
Ionic dysregulations typical of ischemia provoke release of glycine and GABA by multiple mechanisms.
    Journal of neurochemistry, 2010, Volume: 114, Issue:4

    Topics: Animals; Brain Ischemia; Exocytosis; gamma-Aminobutyric Acid; Glycine; Hippocampus; Mice; Mitochondr

2010
Decreased vasoconstrictor responses in remote cerebral arteries after focal brain ischemia and reperfusion in the rat, in vitro.
    European journal of pharmacology, 2010, Oct-10, Volume: 644, Issue:1-3

    Topics: Animals; Brain Ischemia; Cerebral Arteries; Free Radical Scavengers; Glycine; Infarction, Middle Cer

2010
Cerebral ischemia elicits aberration in myocardium contractile function and intracellular calcium handling.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 26, Issue:3

    Topics: Aniline Compounds; Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels, L-T

2010
Spreading depression and related events are significant sources of neuronal Zn2+ release and accumulation.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:4

    Topics: Animals; Brain Ischemia; Carrier Proteins; Cation Transport Proteins; Chelating Agents; Cortical Spr

2011
Effects of euthanasia on brain physiological activities monitored in real-time.
    Neurological research, 2002, Volume: 24, Issue:7

    Topics: Amides; Animals; Brain; Brain Ischemia; Carbon Dioxide; Cats; Cerebrovascular Circulation; Drug Comb

2002
Atrial natriuretic peptide expression is increased in rat cerebral cortex following spreading depression: possible contribution to sd-induced neuroprotection.
    Neuroscience, 2003, Volume: 118, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Brain Ischemia; Cell Survival; Cerebral Cortex; Cerebral Infarct

2003
The free radical spin-trap alpha-PBN attenuates periinfarct depolarizations following permanent middle cerebral artery occlusion in rats without reducing infarct volume.
    Brain research, 2003, Nov-14, Volume: 990, Issue:1-2

    Topics: Animals; Body Temperature; Brain Ischemia; Cerebrovascular Circulation; Cortical Spreading Depressio

2003
Compromised metabolic recovery following spontaneous spreading depression in the penumbra.
    Brain research, 2004, Mar-05, Volume: 999, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Cortical Spre

2004
Transcriptional response to circumscribed cortical brain ischemia: spatiotemporal patterns in ischemic vs. remote non-ischemic cortex.
    The European journal of neuroscience, 2004, Volume: 19, Issue:7

    Topics: AIDS-Related Complex; Animals; Brain Ischemia; Carrier Proteins; Cathepsin K; Cathepsins; Cdc20 Prot

2004
Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus.
    Journal of neurochemistry, 2004, Volume: 90, Issue:5

    Topics: 4-Aminopyridine; Animals; Animals, Newborn; Brain Ischemia; Chelating Agents; Chlorocebus aethiops;

2004
Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-alpha.
    Glia, 2005, Aug-01, Volume: 51, Issue:2

    Topics: Animals; Animals, Newborn; Astrocytes; Brain Ischemia; Cell Communication; Cells, Cultured; Dose-Res

2005
Induced spreading depression activates persistent neurogenesis in the subventricular zone, generating cells with markers for divided and early committed neurons in the caudate putamen and cortex.
    Stroke, 2005, Volume: 36, Issue:7

    Topics: Animals; Antimetabolites; Apoptosis; Biomarkers; Brain; Brain Ischemia; Bromodeoxyuridine; Cell Diff

2005
Differential effect of PARP-2 deletion on brain injury after focal and global cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2006, Volume: 26, Issue:1

    Topics: Animals; Brain Ischemia; Cardiopulmonary Resuscitation; Cell Death; Disease Models, Animal; Heart Ar

2006
Involvement of calmodulin in neuronal cell death.
    Brain research, 2006, Apr-14, Volume: 1083, Issue:1

    Topics: Animals; Binding Sites; Brain; Brain Ischemia; Calcium; Calcium Signaling; Calmodulin; Cell Death; C

2006
Cerebral preconditioning using cortical application of hypertonic salt solutions: upregulation of mRNAs encoding inhibitors of inflammation.
    Brain research, 2006, Jun-30, Volume: 1097, Issue:1

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Hypertonic Solutions; Male; Potassium Chloride; Rats; Rats

2006
Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Down-Regulation; Excitator

2008
Prevention and reduction of neural damage in ischemic strokes by w-(N,N'-diethylamino)-n-alkyl-3,4,5-trimethoxybenzoate compounds.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Animals; Aorta; Brain Ischemia; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex;

1995
Temperature-dependent Ca2+ mobilization induced by hypoxia-hypoglycemia in the monkey hippocampal slices.
    Biochemical and biophysical research communications, 1994, Dec-30, Volume: 205, Issue:3

    Topics: Animals; Brain Ischemia; Calcium; Hippocampus; Hypoglycemia; Hypoxia, Brain; Immunohistochemistry; I

1994
Immediate and delayed effects of in vitro ischemia on glutamate efflux from guinea-pig cerebral cortex slices.
    Brain research, 1997, Mar-21, Volume: 751, Issue:2

    Topics: Animals; Brain Ischemia; Calcium; Cerebral Cortex; Female; Glutamic Acid; Guinea Pigs; Hypoxia; In V

1997
Altered function of inward rectifier potassium channels in cerebrovascular smooth muscle after ischemia/reperfusion.
    Stroke, 1998, Volume: 29, Issue:7

    Topics: Animals; Barium Compounds; Brain Ischemia; Cerebral Arteries; Chlorides; Endothelium, Vascular; Male

1998
Spreading depression-induced gene expression is regulated by plasma glucose.
    Stroke, 1999, Volume: 30, Issue:1

    Topics: Animals; Blood Gas Analysis; Blood Glucose; Brain Chemistry; Brain Ischemia; Cortical Spreading Depr

1999
Correlation between tissue depolarizations and damage in focal ischemic rat brain.
    Brain research, 1999, Sep-04, Volume: 840, Issue:1-2

    Topics: Animals; Brain; Brain Ischemia; Cortical Spreading Depression; Electrophysiology; Ischemic Attack, T

1999
Infarct tolerance accompanied enhanced BDNF-like immunoreactivity in neuronal nuclei.
    Brain research, 2000, Sep-22, Volume: 877, Issue:2

    Topics: Animals; Astrocytes; Brain; Brain Infarction; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cor

2000
Preconditioning with spreading depression activates specifically protein kinase Cdelta.
    Neuroreport, 2001, Feb-12, Volume: 12, Issue:2

    Topics: Animals; Blotting, Northern; Brain Ischemia; Cortical Spreading Depression; Cytosol; Enzyme Activati

2001
Induction of astrocytic nestin expression by depolarization in rats.
    Neuroscience letters, 2001, Nov-16, Volume: 314, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Brain Injuries; Brain Ischemia; Cell Differentiation; Cerebral Corte

2001
Protective effect of minaprine against the abnormal changes of 2-deoxyglucose uptake by rat hippocampal slices induced by hypoxia/hypoglycemia.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:1

    Topics: Acetylcholine; Animals; Brain Ischemia; Central Nervous System Stimulants; Deoxyglucose; Hippocampus

1992
Use of cell cultures to differentiate among effects of various ischemia factors on astrocytic cell volume.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70 Suppl

    Topics: Animals; Animals, Newborn; Astrocytes; Body Water; Brain Ischemia; Cells, Cultured; Extracellular Sp

1992
Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:3

    Topics: Animals; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Disease Models, Anim

1992
Ischemia-reperfusion does not affect reactivity of isolated canine basilar artery.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:5

    Topics: Animals; Basilar Artery; Bradykinin; Brain Ischemia; Cerebrovascular Circulation; Dogs; Endothelium;

1991
Protection of ischaemic synaptosomes from calcium overload by addition of exogenous lactate.
    Journal of neurochemistry, 1991, Volume: 57, Issue:1

    Topics: Acetylcholine; Animals; Brain Ischemia; Calcium; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lact

1991
Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection.
    Cellular and molecular neurobiology, 1990, Volume: 10, Issue:3

    Topics: Animals; Blood; Brain Ischemia; Heart Arrest; Hypoglycemia; Hypoxanthine; Hypoxanthines; Hypoxia; In

1990
Measurement of ischemic changes in cerebral blood flow by the hydrogen clearance technique and brain cortical temperature. Influence of flunarizine.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 281, Issue:2

    Topics: Animals; Body Temperature; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Cinnarizine

1986
[Pharmacological studies on Y-8894. (IV). Ameliorative effect on a cerebral energy metabolism disorder induced by KCN].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Energy Metabolism; Hypoxia, Brain; Male; Mice; Mice, Inbred Strains;

1986
Comparative actions of pentobarbital and verapamil on canine cerebral and peripheral arteries in vitro.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:2

    Topics: Animals; Arteries; Brain Ischemia; Calcium; Cerebral Arteries; Dinoprost; Dogs; Female; In Vitro Tec

1985