potassium chloride has been researched along with Cardiovascular Diseases in 24 studies
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our aims was to determine to what extent salts of potassium could substitute sodium chloride and potassium-rich soya flour could replace wheat flour without detrimental effect on acceptability, and to measure the bioavailability of a potassium salt added to bread." | 2.74 | Partial substitution of sodium with potassium in white bread: feasibility and bioavailability. ( Braschi, A; Gill, L; Naismith, DJ, 2009) |
| " Our clinical pathway for sustained release potassium chloride creates dosing restrictions designed to prevent hyperkalemia, while allowing exceptions for patients with high requirements." | 1.46 | Potassium Chloride Sustained Release Dosing Pathway in an Academic Medical Center. ( Carter, DM; Cook, BM; Dell'Orfano, H; Matta, L, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, DW | 1 |
| Clark, D | 1 |
| Morgan, TO | 1 |
| He, FJ | 1 |
| Jacobson, MF | 1 |
| Campbell, NRC | 2 |
| Marklund, M | 1 |
| Singh, G | 1 |
| Greer, R | 1 |
| Cudhea, F | 1 |
| Matsushita, K | 1 |
| Micha, R | 1 |
| Brady, T | 1 |
| Zhao, D | 1 |
| Huang, L | 1 |
| Tian, M | 1 |
| Cobb, L | 1 |
| Neal, B | 1 |
| Appel, LJ | 1 |
| Mozaffarian, D | 1 |
| Wu, JHY | 1 |
| Chatterjee, R | 1 |
| Davenport, CA | 1 |
| Kwee, L | 1 |
| D'Alessio, D | 1 |
| Svetkey, LP | 1 |
| Lin, PH | 1 |
| Slentz, CA | 1 |
| Ilkayeva, O | 1 |
| Johnson, J | 1 |
| Edelman, D | 1 |
| Shah, SH | 1 |
| Cook, BM | 1 |
| Carter, DM | 1 |
| Dell'Orfano, H | 1 |
| Matta, L | 1 |
| Farrand, C | 1 |
| MacGregor, G | 1 |
| Webster, J | 1 |
| Bruder-Nascimento, T | 1 |
| Campos, DH | 1 |
| Cicogna, AC | 1 |
| Cordellini, S | 1 |
| Braschi, A | 1 |
| Gill, L | 1 |
| Naismith, DJ | 1 |
| Cherng, TW | 1 |
| Campen, MJ | 1 |
| Knuckles, TL | 1 |
| Gonzalez Bosc, L | 1 |
| Kanagy, NL | 1 |
| Chung, AW | 1 |
| Yang, HH | 1 |
| Kim, JM | 1 |
| Sigrist, MK | 1 |
| Chum, E | 1 |
| Gourlay, WA | 1 |
| Levin, A | 1 |
| Kapil, V | 1 |
| Milsom, AB | 1 |
| Okorie, M | 1 |
| Maleki-Toyserkani, S | 1 |
| Akram, F | 1 |
| Rehman, F | 1 |
| Arghandawi, S | 1 |
| Pearl, V | 1 |
| Benjamin, N | 1 |
| Loukogeorgakis, S | 1 |
| Macallister, R | 1 |
| Hobbs, AJ | 1 |
| Webb, AJ | 1 |
| Ahluwalia, A | 1 |
| Bosnjak, JJ | 1 |
| Terata, K | 1 |
| Miura, H | 1 |
| Sato, A | 1 |
| Nicolosi, AC | 1 |
| McDonald, M | 1 |
| Manthei, SA | 1 |
| Saito, T | 1 |
| Hatoum, OA | 1 |
| Gutterman, DD | 1 |
| Garlicki, M | 1 |
| Fortuño, A | 1 |
| Rodríguez, A | 1 |
| Gómez-Ambrosi, J | 1 |
| Frühbeck, G | 1 |
| Díez, J | 1 |
| PENNA, M | 1 |
| ILLANES, A | 1 |
| PUPKIN, M | 1 |
| Chang, HY | 1 |
| Hu, YW | 1 |
| Yue, CS | 1 |
| Wen, YW | 1 |
| Yeh, WT | 1 |
| Hsu, LS | 1 |
| Tsai, SY | 1 |
| Pan, WH | 1 |
| Chow, CK | 1 |
| Wattanapitayakul, SK | 1 |
| Weinstein, DM | 1 |
| Holycross, BJ | 1 |
| Bauer, JA | 1 |
| Okatani, Y | 1 |
| Wakatsuki, A | 1 |
| Reiter, RJ | 1 |
| Gorodinskaia, VIa | 1 |
| Günther, KH | 1 |
| Goulon, M | 1 |
| Giec, L | 1 |
| Schou, M | 1 |
| Amdisen, A | 1 |
| Trap-Jensen, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Potassium on Glucose Metabolism in African Americans[NCT02236598] | Phase 2 | 61 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Investigation of the Sex Differences in Oral Microbiota and Their Effect on Circulating Nitrite Levels[NCT01583803] | 24 participants (Anticipated) | Observational | 2012-06-30 | Active, not recruiting | |||
| The Acute Effect of Beetroot Juice on Circulating Nitrate and Nitrite Levels and Blood Pressure in Normotensives and Hypertensives[NCT01236872] | 15 participants (Actual) | Interventional | 2009-12-31 | Completed | |||
| Angiogenesis Inhibitors and Hypertension: Clinical Aspects[NCT00511511] | 80 participants (Anticipated) | Observational | 2007-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in glucose tolerance, as measured by change in glucose area-under-the-curve (Area Under the Curve (AUC) - measured via the trapezoidal method) of 2 hours from the 3-hour Oral Glucose Tolerance Test (OGTT). (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | AUC - mg*min/dL (Mean) |
|---|---|
| K+ Supplementation | 328 |
| Placebo | 1000 |
Changes in Insulin Secretion as measured by 2-hour insulin area-under-the-curve (AUC - measured via the trapezoidal method) of 2 hours from the 3-hour OGTT. (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | AUC - pg*min/mL (Mean) |
|---|---|
| K+ Supplementation | 71,444 |
| Placebo | 149,327 |
Matsuda Insulin Sensitivity Index was calculated as: 10,000 / square root of [fasting glucose x fasting insulin x mean glucose x mean insulin during Oral Glucose Tolerance Test]). (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | AUC - unitless, (Mean) |
|---|---|
| K+ Supplementation | -0.03 |
| Placebo | -0.87 |
Changes in fasting, 1-hour, and 2-hour post-challenge glucose levels in mg/dL (NCT02236598)
Timeframe: Baseline to 3 months
| Intervention | mg/dL (Mean) | ||
|---|---|---|---|
| Change in Fasting Glucose | Change in 1-Hour Glucose | Change in 2-Hour Glucose | |
| K+ Supplementation | -1.0667 | 0.80 | 3.60 |
| Placebo | 6.0833 | 14.17 | 0.75 |
2 reviews available for potassium chloride and Cardiovascular Diseases
| Article | Year |
|---|---|
Adipose tissue as an endocrine organ: role of leptin and adiponectin in the pathogenesis of cardiovascular diseases.
Topics: Adiponectin; Adipose Tissue; Angiotensin II; Animals; Calcium; Cardiovascular Diseases; Cations, Div | 2003 |
[Combined effect of beta-adrenoblockaders with other pharmacologic agents (review of the literature)].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, Inhalation; Angina Pectoris; | 1971 |
4 trials available for potassium chloride and Cardiovascular Diseases
| Article | Year |
|---|---|
Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease.
Topics: Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Female; Glucose; Humans; Male; Mass Spect | 2020 |
Partial substitution of sodium with potassium in white bread: feasibility and bioavailability.
Topics: Adult; Biological Availability; Bread; Cardiovascular Diseases; Consumer Behavior; Cross-Over Studie | 2009 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.
Topics: Blood Pressure; Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Cyclic GMP; Double-Bli | 2010 |
Effect of potassium-enriched salt on cardiovascular mortality and medical expenses of elderly men.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Health Care Costs; Humans; International Cl | 2006 |
18 other studies available for potassium chloride and Cardiovascular Diseases
| Article | Year |
|---|---|
Potassium-Enriched Salt Substitution as a Population Strategy to Prevent Cardiovascular Disease.
Topics: Cardiovascular Diseases; Humans; Mutation, Missense; Potassium; Potassium Chloride; Sodium, Dietary | 2022 |
Potassium labeling of foods: Potential benefit for blood pressure.
Topics: Blood Pressure; Cardiovascular Diseases; Feeding Behavior; Food Labeling; Humans; Hypertension; Pota | 2019 |
Estimated population wide benefits and risks in China of lowering sodium through potassium enriched salt substitution: modelling study.
Topics: Adult; Aged; Blood Pressure; Cardiovascular Diseases; China; Diet, Sodium-Restricted; Female; Humans | 2020 |
Potassium Chloride Sustained Release Dosing Pathway in an Academic Medical Center.
Topics: Academic Medical Centers; Cardiovascular Diseases; Critical Pathways; Delayed-Action Preparations; D | 2017 |
Potential use of salt substitutes to reduce blood pressure.
Topics: Blood Pressure; Cardiovascular Diseases; Delivery of Health Care; Diet, Sodium-Restricted; Humans; H | 2019 |
Chronic stress improves NO- and Ca2+ flux-dependent vascular function: a pharmacological study.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Calcium; Calcium Chloride; Cardiovascular Diseases; Cortic | 2015 |
Impairment of coronary endothelial cell ET(B) receptor function after short-term inhalation exposure to whole diesel emissions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Air Pollutants; Animals; Cardiov | 2009 |
Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease.
Topics: Acetylcholine; Arteries; Calcinosis; Cardiovascular Diseases; Elasticity; Enzyme Activation; Humans; | 2009 |
Mechanism of thrombin-induced vasodilation in human coronary arterioles.
Topics: Adult; Aged; Arterioles; Cardiovascular Diseases; Charybdotoxin; Chlorates; Coronary Vessels; Endoth | 2003 |
May preservation solution affect the incidence of graft vasculopathy in transplanted heart?
Topics: Adenosine; Adult; Allopurinol; Cardiovascular Diseases; Coronary Vessels; Disaccharides; Electrolyte | 2003 |
Effects of adenosinetriphosphate and potassium chloride on ventricular fibrillation induced by lack of substrates.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Cardiovascular Diseases; Potassium Chloride; Ventricula | 1962 |
Does potassium-enriched salt or sodium reduction reduce cardiovascular mortality and medical expenses?
Topics: Cardiovascular Diseases; Evidence-Based Medicine; Health Care Costs; Humans; Potassium Chloride | 2006 |
Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cardiovascular Diseases; Endothelium, Vascu | 2000 |
Melatonin counteracts potentiation by homocysteine of KCL-induced vasoconstriction in human umbilical artery: relation to calcium influx.
Topics: Antioxidants; Calcium Signaling; Cardiovascular Diseases; Drug Interactions; Female; Free Radical Sc | 2001 |
Control of diuretic treatment in clinical practice.
Topics: Cardiovascular Diseases; Diuretics; Humans; Hypokalemia; Potassium Chloride; Triamterene; Water-Elec | 1973 |
[Acute tranquilizer poisoning].
Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Coma; Diuresis; Female; Gastric Lavage; Glucose; | 1972 |
[Electrocardiographic picture of atrial depolarization in the potassium test].
Topics: Cardiovascular Diseases; Electrocardiography; Humans; Neurocirculatory Asthenia; Potassium Chloride | 1967 |
Lithium poisoning.
Topics: Adult; Aged; Bipolar Disorder; Body Temperature; Body Weight; Carbonates; Cardiovascular Diseases; C | 1968 |