potassium chloride has been researched along with Alzheimer Disease in 15 studies
Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
potassium chloride : A metal chloride salt with a K(+) counterion.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because aging is a risk factor for Alzheimer's disease, we sought to identify changes in PS1 and Syt-1 association during aging in primary neurons in vitro and mouse brain sections ex vivo." | 1.56 | Presenilin 1 increases association with synaptotagmin 1 during normal aging. ( Berezovska, O; Keller, LJ; Maesako, M; Sekula, NM; Svirsky, S; Zoltowska, KM, 2020) |
| "In the hippocampal formation of Alzheimer's disease (AD) patients, both focal and diffuse deposits of Aβ peptides appear in a subregion- and layer-specific manner." | 1.37 | Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms. ( Cynis, H; Demuth, HU; Hartlage-Rübsamen, M; Jäger, C; Koch, B; Morawski, M; Rossner, S; Schilling, S; Schliebs, R; Waniek, A; Zeitschel, U, 2011) |
| "A tetraethylammonium-induced increase of intracellular concentrations of calcium, [Ca2+]i, a response that depends on functional 113-picosiemen potassium channels, was also eliminated or markedly reduced by 10 nM beta-amyloid." | 1.29 | Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels. ( Alkon, DL; Etcheberrigaray, R; Ito, E; Kim, CS, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Keller, LJ | 1 |
| Sekula, NM | 1 |
| Svirsky, S | 1 |
| Maesako, M | 1 |
| Zoltowska, KM | 1 |
| Berezovska, O | 1 |
| Perez de Lara, MJ | 1 |
| Pintor, J | 1 |
| Hascup, KN | 1 |
| Hascup, ER | 1 |
| Lazzari, C | 1 |
| Kipanyula, MJ | 1 |
| Agostini, M | 1 |
| Pozzan, T | 1 |
| Fasolato, C | 1 |
| Deshpande, A | 1 |
| Kawai, H | 1 |
| Metherate, R | 1 |
| Glabe, CG | 1 |
| Busciglio, J | 1 |
| Takaya, T | 1 |
| Okamoto, M | 1 |
| Yodoi, K | 1 |
| Hata, K | 1 |
| Kijima, Y | 1 |
| Nakajima, H | 1 |
| Nishikawa, Y | 1 |
| Kita, T | 1 |
| Ito, M | 1 |
| Seo, T | 1 |
| Kawashima, S | 1 |
| Hartlage-Rübsamen, M | 1 |
| Morawski, M | 1 |
| Waniek, A | 1 |
| Jäger, C | 1 |
| Zeitschel, U | 1 |
| Koch, B | 1 |
| Cynis, H | 1 |
| Schilling, S | 1 |
| Schliebs, R | 1 |
| Demuth, HU | 1 |
| Rossner, S | 1 |
| Zassler, B | 1 |
| Weis, C | 1 |
| Humpel, C | 1 |
| Hook, VY | 1 |
| Reisine, TD | 1 |
| Pierrot, N | 1 |
| Santos, SF | 1 |
| Feyt, C | 1 |
| Morel, M | 1 |
| Brion, JP | 1 |
| Octave, JN | 1 |
| Chow, N | 1 |
| Bell, RD | 1 |
| Deane, R | 1 |
| Streb, JW | 1 |
| Chen, J | 1 |
| Brooks, A | 1 |
| Van Nostrand, W | 1 |
| Miano, JM | 1 |
| Zlokovic, BV | 1 |
| Yoon, SY | 1 |
| Choi, JE | 1 |
| Choi, JM | 1 |
| Kim, DH | 1 |
| Etcheberrigaray, R | 1 |
| Ito, E | 1 |
| Kim, CS | 1 |
| Alkon, DL | 1 |
| Sunaga, K | 1 |
| Takahashi, H | 1 |
| Chuang, DM | 1 |
| Ishitani, R | 1 |
| Kourie, JI | 1 |
| Henry, CL | 1 |
| Farrelly, P | 1 |
15 other studies available for potassium chloride and Alzheimer Disease
| Article | Year |
|---|---|
Presenilin 1 increases association with synaptotagmin 1 during normal aging.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Brain; Calcium; Cells, Cultured; F | 2020 |
Presence and release of ATP from the retina in an Alzheimer's disease model.
Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Disease Models, Animal; Extracellular Space; Fem | 2015 |
Altered neurotransmission prior to cognitive decline in AβPP/PS1 mice, a model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cognition | 2015 |
Aβ42 oligomers selectively disrupt neuronal calcium release.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Cells, Cultured; Cytosol; Endoplasmic Re | 2015 |
A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Calmodulin-Binding Proteins; Carrier Prote | 2009 |
Torsades de Pointes with QT prolongation related to donepezil use.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Colitis; Donepezil; Electrocardiogr | 2009 |
Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-An | 2011 |
Tumor necrosis factor-alpha triggers cell death of sensitized potassium chloride-stimulated cholinergic neurons.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Alzheimer Disease; Animals; Basal Nucleus of Meynert; Ce | 2003 |
Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Ac | 2003 |
Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Calcium; Cell Polarity; Cells, Cultured; | 2006 |
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.
Topics: Alzheimer Disease; Animals; Cells, Cultured; Cerebral Arteries; Humans; Mice; Mice, Inbred C57BL; Nu | 2007 |
Dynein cleavage and microtubule accumulation in okadaic acid-treated neurons.
Topics: Acetylation; Alzheimer Disease; Animals; Biological Transport; Calcium Chloride; Calcium Hydroxide; | 2008 |
Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Bombesin; Calcium; Cell Line; Cells, Cultured; Dimethyl Su | 1994 |
Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer's brain.
Topics: Alzheimer Disease; Amyloid; Animals; Antibodies, Monoclonal; Apoptosis; Blotting, Western; Cells, Cu | 1995 |
Diversity of amyloid beta protein fragment [1-40]-formed channels.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cations; Cesium; Chlorides; Humans; Ion Channel Gating; Io | 2001 |