potassium-bromate has been researched along with Hypersensitivity* in 1 studies
1 other study(ies) available for potassium-bromate and Hypersensitivity
Article | Year |
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Modulation of hypersensitivity to oxidative DNA damage in ATM defective cells induced by potassium bromate by inhibition of the Poly (ADP-ribose) polymerase (PARP).
The ataxia telangiectasia mutated (ATM) protein is a pivotal multifunctional protein kinase predominantly involved in DNA damage response, as well as in maintaining overall functional integrity of the cells. Apart from playing its major role in regulating the cellular response to DNA damage, ATM, when mutated, can additionally determine oxidative stress, metabolic syndrome, mitochondrial dysfunction and neurodegeneration. In the present paper we aim to investigate the levels of oxidative stress potentially induced by the oxidizing rodent renal carcinogen KBrO Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Bromates; Cells, Cultured; DNA Damage; DNA Repair; Humans; Hypersensitivity; Lymphocytes; Oxidative Stress; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors | 2018 |