potassium-bicarbonate and Muscular-Atrophy

potassium-bicarbonate has been researched along with Muscular-Atrophy* in 2 studies

Trials

2 trial(s) available for potassium-bicarbonate and Muscular-Atrophy

Article	Year
Whey protein with potassium bicarbonate supplement attenuates the reduction in muscle oxidative capacity during 19 days of bed rest. Journal of applied physiology (Bethesda, Md. : 1985), 2016, 10-01, Volume: 121, Issue:4 The effectiveness of whey protein plus potassium bicarbonate-enriched diet (WP+KHCO Topics: Administration, Oral; Adult; Bed Rest; Bicarbonates; Dietary Supplements; Humans; Male; Muscular Atrophy; Oxidation-Reduction; Oxygen Consumption; Potassium Compounds; Treatment Outcome; Whey Proteins	2016
Whey protein plus bicarbonate supplement has little effects on structural atrophy and proteolysis marker immunopatterns in skeletal muscle disuse during 21 days of bed rest. Journal of musculoskeletal & neuronal interactions, 2014, Volume: 14, Issue:4 To investigate the effect of whey protein plus potassium bicarbonate supplement on disused skeletal muscle structure and proteolysis after bed rest (BR).. Soleus (SOL) and vastus lateralis (VL) biopsies were sampled from ten (n=10) healthy male subjects (aged 31±6 years) who did BR once with and once without protein supplement as a dietary countermeasure (cross-over study design). The structural changes (myofibre size and type distribution) were analysed by histological sections, and muscle protein breakdown indirectly via the proteolysis markers, calpain 1 and 3, calpastatin, MuRF1 and 2, both in muscle homogenates and by immunohistochemistry.. BR caused size-changes in myofiber cross-sectional area (FCSA, SOL, p=0,004; VL, p=0.03), and myofiber slow-to-fast type transition with increased hybrids (SOL, p=0.043; VL, p=0.037) however with campaign differences in SOL (p<0.033). No significant effect of BR and supplement was found by any of the key proteolysis markers.. Campaign differences in structural muscle adaptation may be an issue in cross-over design BR studies. The whey protein plus potassium bicarbonate supplement did not attenuate atrophy and fibre type transition during medium term bed rest. Alkaline whey protein supplements may however be beneficial as adjuncts to exercise countermeasures in disuse. Topics: Adult; Bed Rest; Bicarbonates; Cross-Over Studies; Dietary Supplements; Humans; Immunohistochemistry; Male; Milk Proteins; Muscular Atrophy; Potassium Compounds; Proteolysis; Whey Proteins; Young Adult	2014

Article

Year

Whey protein with potassium bicarbonate supplement attenuates the reduction in muscle oxidative capacity during 19 days of bed rest.

Journal of applied physiology (Bethesda, Md. : 1985), 2016, 10-01, Volume: 121, Issue:4

The effectiveness of whey protein plus potassium bicarbonate-enriched diet (WP+KHCO

Topics: Administration, Oral; Adult; Bed Rest; Bicarbonates; Dietary Supplements; Humans; Male; Muscular Atrophy; Oxidation-Reduction; Oxygen Consumption; Potassium Compounds; Treatment Outcome; Whey Proteins

2016

Whey protein plus bicarbonate supplement has little effects on structural atrophy and proteolysis marker immunopatterns in skeletal muscle disuse during 21 days of bed rest.

Journal of musculoskeletal & neuronal interactions, 2014, Volume: 14, Issue:4

To investigate the effect of whey protein plus potassium bicarbonate supplement on disused skeletal muscle structure and proteolysis after bed rest (BR).. Soleus (SOL) and vastus lateralis (VL) biopsies were sampled from ten (n=10) healthy male subjects (aged 31±6 years) who did BR once with and once without protein supplement as a dietary countermeasure (cross-over study design). The structural changes (myofibre size and type distribution) were analysed by histological sections, and muscle protein breakdown indirectly via the proteolysis markers, calpain 1 and 3, calpastatin, MuRF1 and 2, both in muscle homogenates and by immunohistochemistry.. BR caused size-changes in myofiber cross-sectional area (FCSA, SOL, p=0,004; VL, p=0.03), and myofiber slow-to-fast type transition with increased hybrids (SOL, p=0.043; VL, p=0.037) however with campaign differences in SOL (p<0.033). No significant effect of BR and supplement was found by any of the key proteolysis markers.. Campaign differences in structural muscle adaptation may be an issue in cross-over design BR studies. The whey protein plus potassium bicarbonate supplement did not attenuate atrophy and fibre type transition during medium term bed rest. Alkaline whey protein supplements may however be beneficial as adjuncts to exercise countermeasures in disuse.

Topics: Adult; Bed Rest; Bicarbonates; Cross-Over Studies; Dietary Supplements; Humans; Immunohistochemistry; Male; Milk Proteins; Muscular Atrophy; Potassium Compounds; Proteolysis; Whey Proteins; Young Adult

2014