ponalrestat has been researched along with Muscle Contraction in 4 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with ponalrestat (25 mg kg-1, daily) prevented both the enhanced maximum contractile responses to phenylephrine and the depressed endothelium-dependent relaxations to carbachol in aortae from 14-day diabetic rats." | 1.29 | The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats. ( Chess-Williams, R; Otter, DJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Otter, DJ | 1 |
| Chess-Williams, R | 1 |
| Taylor, PD | 1 |
| Wickenden, AD | 1 |
| Mirrlees, DJ | 1 |
| Poston, L | 1 |
| Cotter, MA | 2 |
| Cameron, NE | 2 |
| Robertson, S | 2 |
| Ewing, I | 1 |
4 other studies available for ponalrestat and Muscle Contraction
| Article | Year |
|---|---|
The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats.
Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Carbachol; Colforsin; Diabetes Mellitus, Experimental; | 1994 |
Endothelial function in the isolated perfused mesentery and aortae of rats with streptozotocin-induced diabetes: effect of treatment with the aldose reductase inhibitor, ponalrestat.
Topics: Acetylcholine; Aldehyde Reductase; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vas | 1994 |
Polyol pathway-related skeletal muscle contractile and morphological abnormalities in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Male; Muscle Contraction; Muscles; Mus | 1993 |
Changes in skeletal muscle contractile properties in streptozocin-induced diabetic rats and role of polyol pathway and hypoinsulinemia.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Hypoglycemic Agen | 1990 |