ponalrestat has been researched along with Complications of Diabetes Mellitus in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To update readers on research being conducted with the aldose reductase inhibitor (ARI) tolrestat in treating complications of diabetes mellitus." | 4.78 | Aldose reductase inhibitors: an update. ( Burnakis, TG; Tsai, SC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Florkowski, CM | 1 |
| Tsai, SC | 1 |
| Burnakis, TG | 1 |
| Nishinaka, T | 1 |
| Yabe-Nishimura, C | 1 |
| Collier, A | 1 |
| Small, M | 1 |
| Hotta, N | 1 |
| Sakamoto, N | 1 |
| Kador, PF | 1 |
| Kinoshita, JH | 1 |
| Sharpless, NE | 1 |
3 reviews available for ponalrestat and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Aldose reductase inhibitors: an update.
Topics: Aldehyde Reductase; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Imi | 1993 |
[Clinical application of aldose reductase inhibitors--prevention and therapy of diabetic complications].
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies | 1987 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; | 1985 |
1 trial available for ponalrestat and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
The role of aldose reductase inhibitors in the treatment of diabetic peripheral neuropathy.
Topics: Aldehyde Reductase; Diabetes Complications; Diabetic Neuropathies; Double-Blind Method; Humans; Phth | 1993 |
2 other studies available for ponalrestat and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
EGF receptor-ERK pathway is the major signaling pathway that mediates upregulation of aldose reductase expression under oxidative stress.
Topics: Aldehyde Reductase; Animals; Cell Line; Cell Survival; Diabetes Complications; Diabetes Mellitus; Er | 2001 |
The role of the polyol pathway in diabetes mellitus.
Topics: Aldehyde Reductase; Diabetes Complications; Diabetes Mellitus; Glycolysis; Glycosylation; Humans; Hy | 1991 |