ponalrestat has been researched along with Autoimmune Diabetes in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proteinuria was attributed to an increase in albumin and an array of proteins having molecular weights between 30,000 and 100,000 daltons." | 5.28 | Comparison of sorbinil and ponalrestat (Statil) diminution of proteinuria in the BB rat. ( Beyer-Mears, A; Cruz, E; Murray, FT; Rountree, J; Sciadini, M, 1992) |
| " Ponalrestat administration at a dosage of 600 mg daily for 12 months has no significant effect on the course of minimal retinopathy in diabetic patients." | 2.67 | The effects of an aldose reductase inhibitor on the progression of diabetic retinopathy. ( Barendsen, BC; Hooymans, JM; Tromp, A; van Doormaal, JJ, 1991) |
| "Proteinuria was attributed to an increase in albumin and an array of proteins having molecular weights between 30,000 and 100,000 daltons." | 1.28 | Comparison of sorbinil and ponalrestat (Statil) diminution of proteinuria in the BB rat. ( Beyer-Mears, A; Cruz, E; Murray, FT; Rountree, J; Sciadini, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 13 (86.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamijo, M | 1 |
| Cherian, PV | 1 |
| Sima, AA | 2 |
| Boland, OM | 1 |
| Blackwell, CC | 1 |
| Clarke, BF | 1 |
| Ewing, DJ | 1 |
| Tebbs, SE | 2 |
| Lumbwe, CM | 1 |
| Tesfaye, S | 1 |
| Gonzalez, AM | 2 |
| Wilson, RM | 2 |
| Beyer-Mears, A | 1 |
| Murray, FT | 1 |
| Cruz, E | 1 |
| Rountree, J | 1 |
| Sciadini, M | 1 |
| Rosenbloom, AL | 1 |
| Buithieu, M | 1 |
| Jelliffe, KA | 1 |
| Aitchison, RD | 1 |
| Truglia, JA | 1 |
| Ziegler, D | 1 |
| Mayer, P | 1 |
| Rathmann, W | 1 |
| Gries, FA | 1 |
| Tromp, A | 1 |
| Hooymans, JM | 1 |
| Barendsen, BC | 1 |
| van Doormaal, JJ | 1 |
| Passa, P | 1 |
| Leblanc, H | 1 |
| Billault, B | 1 |
| Ramirez, LC | 1 |
| Arauz, C | 1 |
| Pruneda, L | 1 |
| Hammon, K | 1 |
| Rosenstock, J | 1 |
| Raskin, P | 1 |
| Pedersen, MM | 1 |
| Christiansen, JS | 1 |
| Mogensen, CE | 1 |
| Price, DE | 2 |
| Alani, SM | 1 |
| Wales, JK | 2 |
| Ghahary, A | 1 |
| Chakrabarti, S | 1 |
| Murphy, LJ | 1 |
| Airey, CM | 1 |
| Kemp, JV | 1 |
| Perkins, CM | 1 |
| Rillaerts, EG | 1 |
| Vertommen, JJ | 1 |
| De Leeuw, IH | 1 |
1 review available for ponalrestat and Autoimmune Diabetes
| Article | Year |
|---|---|
[Prevention of terminal kidney failure in insulin-dependent diabetics. Current status and prospects].
Topics: Acute Kidney Injury; Aldehyde Reductase; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive A | 1991 |
8 trials available for ponalrestat and Autoimmune Diabetes
| Article | Year |
|---|---|
Effects of ponalrestat, an aldose reductase inhibitor, on neutrophil killing of Escherichia coli and autonomic function in patients with diabetes mellitus.
Topics: Aldehyde Reductase; Analysis of Variance; Autonomic Nervous System; Blood Pressure; Diabetes Mellitu | 1993 |
Effect of an aldose reductase inhibiting agent on limited joint mobility in IDDM.
Topics: Adult; Aldehyde Reductase; Blood Pressure; Diabetes Mellitus, Type 1; Double-Blind Method; Female; G | 1992 |
One-year treatment with the aldose reductase inhibitor, ponalrestat, in diabetic neuropathy.
Topics: Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dou | 1991 |
The effects of an aldose reductase inhibitor on the progression of diabetic retinopathy.
Topics: Adolescent; Adult; Aldehyde Reductase; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabeti | 1991 |
The effect of aldose reductase inhibition with ponalrestat on the width of the capillary basement membrane in diabetes mellitus.
Topics: Aldehyde Reductase; Analysis of Variance; Basement Membrane; Capillaries; Diabetes Mellitus, Type 1; | 1991 |
Reduction of glomerular hyperfiltration in normoalbuminuric IDDM patients by 6 mo of aldose reductase inhibition.
Topics: Adult; Albuminuria; Aldehyde Reductase; Blood Pressure; Diabetes Mellitus, Type 1; Glomerular Filtra | 1991 |
Effect of aldose reductase inhibition on resistance to ischemic conduction block in diabetic subjects.
Topics: Aldehyde Reductase; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double- | 1991 |
The effect of aldose reductase inhibition on erythrocyte polyols and galactitol accumulation in diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, | 1989 |
6 other studies available for ponalrestat and Autoimmune Diabetes
| Article | Year |
|---|---|
The preventive effect of aldose reductase inhibition on diabetic optic neuropathy in the BB/W-rat.
Topics: Aldehyde Reductase; Animals; Atrophy; Axons; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Diabe | 1993 |
The influence of aldose reductase on the oxidative burst in diabetic neutrophils.
Topics: Aldehyde Reductase; Blood Glucose; Diabetes Mellitus, Type 1; Female; Foot Ulcer; Glucose; Glycated | 1992 |
Comparison of sorbinil and ponalrestat (Statil) diminution of proteinuria in the BB rat.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Ty | 1992 |
The role of aldose reductase inhibition in diabetic neutrophil phagocytosis and killing.
Topics: Adult; Aged; Aldehyde Reductase; Candida albicans; Diabetes Mellitus, Type 1; Female; Glucose; Human | 1991 |
Effect of insulin and statil on aldose reductase expression in diabetic rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Blotting, Northern; Body Weight; Diabetes Mellitus, Type | 1991 |
Effect of statil (ICI 128436) on erythrocyte viscosity in vitro.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Erythrocyte Deformability; Erythrocytes; Female; Hu | 1988 |