ponalrestat has been researched along with Alloxan Diabetes in 53 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " To compare the relative importance of sorbitol dehydrogenase versus aldose reductase inhibition on sugar cataract formation, cataract formation was monitored in 50% galactose-fed and diabetic rats treated with/without the sorbitol dehydrogenase inhibitors SDH-1 or SDH-2 or the aldose reductase inhibitors AL 1576 or Ponalrestat." | 7.70 | Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats. ( Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF, 1998) |
| " To compare the relative importance of sorbitol dehydrogenase versus aldose reductase inhibition on sugar cataract formation, cataract formation was monitored in 50% galactose-fed and diabetic rats treated with/without the sorbitol dehydrogenase inhibitors SDH-1 or SDH-2 or the aldose reductase inhibitors AL 1576 or Ponalrestat." | 3.70 | Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats. ( Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF, 1998) |
| "The relative importance of sorbitol formation versus nonenzymatic glycosylation and advanced glycosylation end products (AGEs) on sugar cataract formation was examined in diabetic rats." | 3.70 | Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats. ( Blessing, K; Fujisawa, S; Kador, PF; Lee, JW; Lou, MF, 2000) |
| "Pretreatment with ponalrestat (25 mg kg-1, daily) prevented both the enhanced maximum contractile responses to phenylephrine and the depressed endothelium-dependent relaxations to carbachol in aortae from 14-day diabetic rats." | 1.29 | The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats. ( Chess-Williams, R; Otter, DJ, 1994) |
| "4." | 1.28 | Diabetes-induced changes in cardiac beta-adrenoceptor responsiveness: effects of aldose reductase inhibition with ponalrestat. ( Austin, CE; Chess-Williams, R, 1991) |
| "Ponalrestat treatment prevented both changes in the 30-day study but did not prevent a depression of responses to acetylcholine in the 6-month study." | 1.28 | Effects of diabetes on cholinergic transmission in two rat gut preparations. ( Lucas, PD; Sardar, AM, 1991) |
| "Ponalrestat treatment completely prevented the characteristic nerve conduction slowing and structural abnormalities of the node of Ranvier for 4 mo despite only partial preservation of axonal integrity." | 1.28 | Preventive effect of long-term aldose reductase inhibition (ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic Bio-Breeding rat. ( Chakrabarti, S; Greene, DA; Prashar, A; Sima, AA; Zhang, WX, 1990) |
| "Myo-inositol treatment also partially prevented the rise in adrenal adrenaline." | 1.28 | Tissue noradrenaline and the polyol pathway in experimentally diabetic rats. ( Lucas, PD; Qirbi, A, 1989) |
| "With ponalrestat treatment, the increase in contraction time was only 11%, and relaxation was only slowed by 4% (p less than 0." | 1.28 | Contractile properties of cardiac papillary muscle in streptozotocin-diabetic rats and the effects of aldose reductase inhibition. ( Cameron, NE; Cotter, MA; Robertson, S, 1989) |
| "Myo-inositol treatment did not affect nerve levels." | 1.28 | The effect of aldose reductase inhibition on the pattern of nerve conduction deficits in diabetic rats. ( Cameron, NE; Cotter, MA; Robertson, S, 1989) |
| "Ponalrestat treatment was started at day 3 after streptozotocin injection and was continued for the whole experimental period, i." | 1.28 | Impaired nerve regeneration in streptozotocin-diabetic rats. Effects of treatment with an aldose reductase inhibitor. ( Ekström, AR; Tomlinson, DR, 1989) |
| "This study examined the effect of streptozotocin diabetes of 5 weeks duration on the profile of slow orthogradely transported radiolabelled protein in rat sciatic motoneurones." | 1.27 | Slow orthograde axonal transport of radiolabelled protein in sciatic motoneurones of rats with short-term experimental diabetes: effects of treatment with an aldose reductase inhibitor or myo-inositol. ( Mayer, JH; McLean, WG; Tomlinson, DR, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (45.28) | 18.7374 |
| 1990's | 28 (52.83) | 18.2507 |
| 2000's | 1 (1.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lipinski, CA | 1 |
| Aldinger, CE | 1 |
| Beyer, TA | 2 |
| Bordner, J | 1 |
| Burdi, DF | 1 |
| Bussolotti, DL | 1 |
| Inskeep, PB | 1 |
| Siegel, TW | 2 |
| Mylari, BL | 1 |
| Wrobel, J | 1 |
| Millen, J | 1 |
| Sredy, J | 1 |
| Dietrich, A | 1 |
| Gorham, BJ | 1 |
| Malamas, M | 1 |
| Kelly, JM | 1 |
| Bauman, JG | 1 |
| Harrison, MC | 1 |
| Jones, LR | 1 |
| Negoro, T | 1 |
| Murata, M | 1 |
| Ueda, S | 1 |
| Fujitani, B | 1 |
| Ono, Y | 1 |
| Kuromiya, A | 1 |
| Komiya, M | 1 |
| Suzuki, K | 1 |
| Matsumoto, J | 1 |
| Mayer, JH | 1 |
| Tomlinson, DR | 10 |
| McLean, WG | 3 |
| Zoubi, SA | 1 |
| Williams, MD | 1 |
| Mayhew, TM | 3 |
| Sparrow, RA | 1 |
| Lightman, S | 1 |
| Soulis-Liparota, T | 1 |
| Cooper, ME | 1 |
| Dunlop, M | 1 |
| Jerums, G | 1 |
| Otter, DJ | 1 |
| Chess-Williams, R | 2 |
| Taylor, PD | 2 |
| Poston, L | 2 |
| Wickenden, AD | 1 |
| Mirrlees, DJ | 2 |
| Calcutt, NA | 4 |
| Mizisin, AP | 1 |
| Kalichman, MW | 1 |
| Phillips, SA | 2 |
| Mirrlees, D | 2 |
| Thronalley, PJ | 1 |
| Thornalley, PJ | 1 |
| Cotter, MA | 4 |
| Cameron, NE | 4 |
| Robertson, S | 4 |
| Ewing, I | 1 |
| Belai, A | 1 |
| Carrington, AL | 1 |
| Diemel, LT | 1 |
| Burnstock, G | 1 |
| Kador, PF | 2 |
| Inoue, J | 1 |
| Secchi, EF | 1 |
| Lizak, MJ | 1 |
| Rodriguez, L | 1 |
| Mori, K | 1 |
| Greentree, W | 1 |
| Blessing, K | 2 |
| Lackner, PA | 1 |
| Sato, S | 1 |
| Lee, JW | 1 |
| Fujisawa, S | 1 |
| Lou, MF | 1 |
| Yasuda, H | 1 |
| Sonobe, M | 1 |
| Hisanaga, T | 1 |
| Kawabata, T | 1 |
| Maeda, K | 1 |
| Kikkawa, R | 1 |
| Shigeta, Y | 1 |
| Williams, M | 1 |
| Bradbury, MW | 1 |
| Lightman, SL | 1 |
| Yuen, L | 1 |
| Pinter, GG | 1 |
| Kamijo, M | 1 |
| Yagihashi, S | 1 |
| Austin, CE | 1 |
| Lucas, PD | 3 |
| Sardar, AM | 1 |
| Chang, WP | 1 |
| Dimitriadis, E | 1 |
| Allen, T | 1 |
| Dunlop, ME | 1 |
| Cooper, M | 1 |
| Larkins, RG | 1 |
| Law, SC | 1 |
| King, RG | 1 |
| Sima, AA | 1 |
| Prashar, A | 1 |
| Zhang, WX | 1 |
| Chakrabarti, S | 1 |
| Greene, DA | 1 |
| Mizuno, A | 1 |
| Toshima, S | 1 |
| Mori, Y | 1 |
| Pekiner, C | 1 |
| Townsend, J | 3 |
| Fretten, P | 1 |
| Sidenius, P | 1 |
| Larsen, JR | 1 |
| Whiteley, SJ | 1 |
| Willars, GB | 5 |
| Dahlin, LB | 1 |
| Archer, DR | 1 |
| Robinson, JP | 1 |
| Keen, P | 1 |
| Compton, AM | 1 |
| Churchill, RD | 1 |
| Daniels, BS | 1 |
| Hostetter, TH | 1 |
| Qirbi, A | 1 |
| Vicario, PP | 1 |
| Slater, EE | 1 |
| Saperstein, R | 1 |
| Ekström, AR | 1 |
| Carson, FL | 1 |
| Sharma, AK | 2 |
| Poulsom, R | 1 |
| Kurkinen, M | 1 |
| Prockop, DJ | 1 |
| Boot-Handford, RP | 1 |
| Kofo-Abayomi, A | 1 |
| Bhoyrul, S | 1 |
| Stribling, D | 2 |
| Mirrlees, DD | 1 |
| Peterson, RG | 1 |
| Farber, MO | 1 |
| Thomas, PK | 1 |
| Sochor, M | 1 |
| Kunjara, S | 1 |
| McLean, P | 1 |
| Price, DE | 1 |
| Airey, CM | 1 |
| Alani, SM | 1 |
| Wales, JK | 1 |
| Terubayashi, H | 1 |
| Akagi, Y | 1 |
| Takahashi, Y | 1 |
| Ikebe, H | 1 |
| Miyamoto, Y | 1 |
| Ibaraki, N | 1 |
| Yokoi, N | 1 |
| Tutumi, M | 1 |
| Itoi, M | 1 |
| Naeser, P | 1 |
| Brolin, SE | 1 |
| Eriksson, UJ | 1 |
| Harrison, HE | 1 |
| Earl, DC | 1 |
1 review available for ponalrestat and Alloxan Diabetes
| Article | Year |
|---|---|
Does aldose reductase have a role in the development of the ocular complications of diabetes?
Topics: Aldehyde Reductase; Animals; Cataract; Clinical Trials as Topic; Corneal Diseases; Diabetes Mellitus | 1993 |
52 other studies available for ponalrestat and Alloxan Diabetes
| Article | Year |
|---|---|
Hydantoin bioisosteres. In vivo active spiro hydroxy acetic acid aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Chromans; Diabetes Mellitus, Experimental; Dose-Response Relationship, | 1992 |
A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners.
Topics: Alcohol Dehydrogenase; Aldehyde Reductase; Animals; Chemical Phenomena; Chemistry; Diabetes Mellitus | 1991 |
Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Cattle; Chemical Phenomena; Chemistry; Diabetes M | 1991 |
Novel, highly potent aldose reductase inhibitors: (R)-(-)-2-(4-bromo-2-fluorobenzyl)-1,2,3,4- tetrahydropyrrolo[1,2-a]pyrazine -4-spiro-3'-pyrrolidine-1,2',3,5'-tetrone (AS-3201) and its congeners.
Topics: Aldehyde Reductase; Animals; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Enzyme Inhibit | 1998 |
Slow orthograde axonal transport of radiolabelled protein in sciatic motoneurones of rats with short-term experimental diabetes: effects of treatment with an aldose reductase inhibitor or myo-inositol.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Carbohydrate Metabolism; Diabetes Mellitus, Experimen | 1984 |
Number and ultrastructure of epithelial cells in crypts and villi along the streptozotocin-diabetic small intestine: a quantitative study on the effects of insulin and aldose reductase inhibition.
Topics: Animals; Cell Count; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Epithelium; Insulin; Intest | 1995 |
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat.
Topics: Albuminuria; Aldehyde Reductase; Animals; Antioxidants; Blood Glucose; Body Weight; Butylated Hydrox | 1995 |
The effects of aldose reductase inhibition with ponalrestat on changes in vascular function in streptozotocin diabetic rats.
Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Carbachol; Colforsin; Diabetes Mellitus, Experimental; | 1994 |
The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Hyperglycemia; In | 1994 |
Endothelial function in the isolated perfused mesentery and aortae of rats with streptozotocin-induced diabetes: effect of treatment with the aldose reductase inhibitor, ponalrestat.
Topics: Acetylcholine; Aldehyde Reductase; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vas | 1994 |
Aldose reductase inhibition, Doppler flux and conduction in diabetic rat nerve.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Female; La | 1994 |
Modification of the glyoxalase system in streptozotocin-induced diabetic rats and the effect of the aldose reductase inhibitor Statil.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Lactates; Lactoylglutathione Lyase; Le | 1993 |
Modification of the glyoxalase system in streptozotocin-induced diabetic rats. Effect of the aldose reductase inhibitor Statil.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Kidney; Lactates; Lacto | 1993 |
Polyol pathway-related skeletal muscle contractile and morphological abnormalities in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Male; Muscle Contraction; Muscles; Mus | 1993 |
Enteric neuropeptides in streptozotocin-diabetic rats; effects of insulin and aldose reductase inhibition.
Topics: Aldehyde Reductase; Animals; Antibody Specificity; Axons; Calcitonin Gene-Related Peptide; Diabetes | 1996 |
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes | 1998 |
Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Diabetes Mellitus, Experimental; Enzyme Inhibito | 2000 |
A combination of the aldose reductase inhibitor, statil, and the prostaglandin E1 analogue, OP1206.alpha CD, completely improves sciatic motor nerve conduction velocity in streptozocin-induced chronically diabetic rats.
Topics: Aldehyde Reductase; Alprostadil; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hy | 1992 |
Responses of enterocyte microvilli in experimental diabetes to insulin and an aldose reductase inhibitor (ponalrestat).
Topics: Aldehyde Reductase; Animals; Body Weight; Diabetes Mellitus, Experimental; Epithelium; Hypoglycemic | 1992 |
Permeability of blood-brain and blood-nerve barriers in experimental diabetes mellitus in the anaesthetized rat.
Topics: Aldehyde Reductase; Animals; Blood Gas Analysis; Blood Glucose; Blood-Brain Barrier; Body Weight; Ca | 1991 |
[Diabetes mellitus and its complications in Japan. Polyol pathway and diabetic neuropathy: selective preventive effect of aldose reductase inhibitor on the experimental diabetic neuropathy].
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Peripheral Nerv | 1991 |
Diabetes-induced changes in cardiac beta-adrenoceptor responsiveness: effects of aldose reductase inhibition with ponalrestat.
Topics: Aldehyde Reductase; Animals; Calcium; Colforsin; Diabetes Mellitus, Experimental; Dihydroalprenolol; | 1991 |
Effects of diabetes on cholinergic transmission in two rat gut preparations.
Topics: Aldehyde Reductase; Animals; Cholinergic Fibers; Diabetes Mellitus, Experimental; Esophagus; Ileum; | 1991 |
The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus.
Topics: 6-Ketoprostaglandin F1 alpha; Albuminuria; Aldehyde Reductase; Animals; Blood Glucose; Body Weight; | 1991 |
Effects of ponalrestat on depressor responses to arachidonic acid in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Body Weight; Diabe | 1990 |
Changes in skeletal muscle contractile properties in streptozocin-induced diabetic rats and role of polyol pathway and hypoinsulinemia.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet; Hypoglycemic Agen | 1990 |
Preventive effect of long-term aldose reductase inhibition (ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic Bio-Breeding rat.
Topics: Aldehyde Reductase; Animals; Axons; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropa | 1990 |
Confirmation of lens hydration by Raman spectroscopy.
Topics: Aldehyde Reductase; Animals; Body Water; Cataract; Diabetes Mellitus, Experimental; Hypoglycemic Age | 1990 |
Impaired induction of nerve ornithine decarboxylase activity in the streptozotocin-diabetic rat is prevented by the aldose reductase inhibitor ponalrestat.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Ind | 1990 |
Prevention of defective axonal transport in streptozocin-diabetic rats by treatment with "Statil" (ICI 128436), an aldose reductase inhibitor.
Topics: Animals; Autonomic Fibers, Preganglionic; Axonal Transport; Blood Glucose; Choline O-Acetyltransfera | 1985 |
Slow component-a of axonal transport, nerve myo-inositol, and aldose reductase inhibition in streptozocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Diabetes Mellitus, Experimental; Fructose; Ganglia, S | 1986 |
Fast anterograde axonal transport in wasted and non-wasted diabetic rats; effects of aldose reductase inhibition.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Blood Glucose; Body Temperature; Diabetes Mellitus, E | 1986 |
Reduced anterograde and retrograde accumulation of axonally transported phosphofructokinase in streptozotocin-diabetic rats: effects of insulin and the aldose reductase inhibitor 'Statil'.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Blood Glucose; Body Weight; Diabetes Mellitus, Experi | 1987 |
Treatment with an aldose reductase inhibitor can reduce the susceptibility of fast axonal transport following nerve compression in the streptozotocin-diabetic rat.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Diabetes Mellitus, Experimental; Diabetic Neuropathie | 1987 |
Axonal transport and tissue contents of substance P in rats with long-term streptozotocin-diabetes. Effects of the aldose reductase inhibitor 'statil'.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Body Weight; Diabetes Mellitus, Experimental; Ganglia | 1987 |
Studies on peripheral nerve and lens in long-term experimental diabetes: effects of the aldose reductase inhibitor statil.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Body Weight; Carbohydrates; Choline O-Acetyltransfera | 1988 |
Aldose reductase inhibition and glomerular abnormalities in diabetic rats.
Topics: Albuminuria; Aldehyde Reductase; Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimenta | 1989 |
Tissue noradrenaline and the polyol pathway in experimentally diabetic rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Experimental; Diet; I | 1989 |
Contractile properties of cardiac papillary muscle in streptozotocin-diabetic rats and the effects of aldose reductase inhibition.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Electric Stimulation; Heart Ventricles | 1989 |
The effect of ponalrestat on sorbitol levels in the lens of obese and diabetic mice.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Insu | 1989 |
The effect of aldose reductase inhibition on the pattern of nerve conduction deficits in diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inositol; Kinet | 1989 |
Impaired nerve regeneration in streptozotocin-diabetic rats. Effects of treatment with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Nerve Crush | 1989 |
Small intestinal morphology in experimental diabetic rats: a stereological study on the effects of an aldose reductase inhibitor (ponalrestat) given with or without conventional insulin therapy.
Topics: Analysis of Variance; Animals; Body Weight; Diabetes Mellitus, Experimental; Drug Therapy, Combinati | 1989 |
Increased steady-state levels of laminin B1 mRNA in kidneys of long-term streptozotocin-diabetic rats. No effect of an aldose reductase inhibitor.
Topics: Aging; Aldehyde Reductase; Animals; Collagen; Diabetes Mellitus, Experimental; DNA; DNA Restriction | 1988 |
Muscarinic receptor density is reduced in diabetic rat atria, an effect prevented by the aldose reductase inhibitor, Statil.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Kinetics; Male; Myocardium; Phthalazin | 1987 |
Ultrastructural observations on myelinated fibres in experimental diabetes: effect of the aldose reductase inhibitor ponalrestat given alone or in conjunction with insulin therapy.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Therapy, Combinati | 1988 |
The effect of aldose reductase inhibitor Statil (ICI 128436) on the glucose over-utilization in kidney of diabetic rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Glucose; Glucuronates; Kidney; Lactates; Orga | 1988 |
Statil-sensitive polyol formation in nerve of galactose-fed mice.
Topics: Aldehyde Reductase; Animals; Carbohydrates; Diabetes Mellitus, Experimental; Galactitol; Galactose; | 1988 |
Effect of aldose reductase inhibition on nerve conduction velocity and resistance to ischemic conduction block in experimental diabetes.
Topics: Action Potentials; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Inositol; Insulin; | 1988 |
[Prevention of experimental diabetic corneal endotheliopathy with a new aldose reductase inhibitor].
Topics: Aldehyde Reductase; Animals; Corneal Diseases; Diabetes Mellitus, Experimental; Endothelium, Corneal | 1988 |
Sorbitol metabolism in the retina, optic nerve, and sural nerve of diabetic rats treated with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Female; L-Iditol 2-Dehydrogenase; Opti | 1988 |
Properties of ICI 128,436, a novel aldose reductase inhibitor, and its effects on diabetic complications in the rat.
Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Diabetes Mellitus, Experimental; Dogs; Erythrocytes; | 1985 |