Page last updated: 2024-09-04

pomalidomide and HbS Disease

pomalidomide has been researched along with HbS Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Abdulmalik, O; Blobel, GA; Giardine, BM; Hardison, RC; Huang, P; Keller, CA; Khandros, E; Peslak, SA; Sharma, M; Zhang, Z1
Al Abed, Y; Blanc, L; Chung, MC; Costa, FF; de Melo, TRF; de Souza, CM; Dos Santos, JL; Dulmovits, BM; Fernandes, GFDS; He, M; Lanaro, C1
Al-Abed, Y; Allen, SL; An, X; Appiah-Kubi, AO; Blanc, L; Chan, KW; Didier, S; Dulmovits, BM; Gallagher, PG; Gould, M; Hale, J; He, M; Husain-Krautter, S; Lipton, JM; Liu, JM; Marambaud, P; Mohandas, N; Papoin, J; Singh, SA; Taylor, N; Vlachos, A1
Corral, LG; Kutlar, A; Kutlar, F; Meiler, SE; Moutouh-de Parseval, LA; Swerdlow, PS; Wade, M; Xue, Y; Yerigenahally, SD1
Brady, H; Chan, K; Corral, LG; De Parseval, LM; Ferguson, GD; Jensen-Pergakes, K; Jhaveri, U; Morris, CL; Richard, N; Verhelle, D; Wilkey, C; Xie, W1
Brady, H; Chan, K; Corral, LG; Ferguson, GD; Glezer, E; Jensen-Pergakes, K; Morris, CL; Moutouh-de Parseval, LA; Muller, G; Verhelle, D1

Other Studies

6 other study(ies) available for pomalidomide and HbS Disease

ArticleYear
Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Blood, 2020, 05-28, Volume: 135, Issue:22

    Topics: Adult; Anemia, Sickle Cell; Cell Line; Cell Separation; Cells, Cultured; Erythroblasts; Erythroid Cells; Fetal Hemoglobin; Gene Expression Profiling; Hemoglobin A; Humans; Hydroxyurea; Proteomics; RNA, Messenger; Thalidomide

2020
Synthesis and pharmacological evaluation of pomalidomide derivatives useful for sickle cell disease treatment.
    Bioorganic chemistry, 2021, Volume: 114

    Topics: Anemia, Sickle Cell; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Thalidomide

2021
Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
    Blood, 2016, Mar-17, Volume: 127, Issue:11

    Topics: Adult; Anemia, Sickle Cell; beta-Globins; Carrier Proteins; Erythroid Precursor Cells; Erythropoiesis; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation, Developmental; Genetic Vectors; Hematopoietic Stem Cells; Histone Demethylases; Humans; Ikaros Transcription Factor; Kruppel-Like Transcription Factors; Lentivirus; Multiple Myeloma; Neoplasm Proteins; Nuclear Proteins; Proteasome Endopeptidase Complex; Repressor Proteins; RNA Interference; RNA, Small Interfering; SOXD Transcription Factors; Thalidomide; Transcription, Genetic

2016
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice.
    Blood, 2011, Jul-28, Volume: 118, Issue:4

    Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Bone Marrow; Disease Models, Animal; Erythropoiesis; Fetal Hemoglobin; Hydroxyurea; Mice; Mice, Knockout; Mice, Transgenic; Thalidomide

2011
Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2.
    Journal of clinical immunology, 2007, Volume: 27, Issue:2

    Topics: Anemia, Sickle Cell; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Synergism; Gene Expression; Humans; Immunologic Factors; Immunoprecipitation; Lipopolysaccharides; Membrane Proteins; Monocytes; Nitrobenzenes; Prostaglandins; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Thalidomide; Transcription, Genetic

2007
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:1

    Topics: Anemia, Sickle Cell; Antigens, CD34; Antineoplastic Agents; Antisickling Agents; beta-Thalassemia; Blood Transfusion; Cells, Cultured; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Synergism; Erythroid Cells; Erythropoiesis; Fetal Hemoglobin; Humans; Hydroxyurea; Lenalidomide; Models, Biological; Thalidomide; Up-Regulation

2008