Page last updated: 2024-09-04

pomalidomide and Benign Neoplasms

pomalidomide has been researched along with Benign Neoplasms in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's8 (53.33)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Chen, J; Ding, X; Elvassore, N; Jiang, B; Kong, Y; Liu, H; Liu, L; Mi, Q; Qiu, X; Ren, C; Shao, Y; Yang, X; Yin, Q; Zhao, Q1
Che, J; Chen, D; Dong, X; Li, J; Luo, X; Mi, T; Rao, Z; Tian, T; Wang, H; Wu, Y; Xu, Y; Zhou, Y; Zhou, Z; Zhu, CL1
An, J; Chen, D; Chen, L; Gu, Z; He, B; Lin, S; Yan, W; Zeng, Z1
Schmidt, C1
Edil, BH; Fujiwara, Y; He, J; Schulick, RD; Sun, Y; Torphy, RJ; Yanaga, K; Zhu, Y1
Agarwal, S; Eddins, MJ; Kodrasov, MP; Kumar, S; LaRocque, JP; Marblestone, JG; Mattern, MR; Nicholson, B; Sterner, DE; Wu, J1
Cervantes, F; Gale, RP; Hudgens, S; Khan, ZM; Mesa, R; Passamonti, F; Rivera, C; Tefferi, A; Tencer, T; Verstovsek, S1
de Rezende, LC; GuimarĂ£es, MC; Rangel, LB; Silva, IV1
Bodera, P; Stankiewicz, W1
Lentzsch, S; Pan, B1
Bokar, J; Cooney, MM; Dowlati, A; Dreicer, R; Gibbons, J; Krishnamurthi, S; Ness, A; Nock, C; Remick, SC; Rodal, MB1
Clarke, IA; Dalgleish, AG; Dredge, K; Marriott, JB; Muller, G; Stirling, D1
Chandula, RS; Chen, RS; Chen, Y; Muller, GW; Stirling, DI; Teo, SK; Thomas, SD1
Bartlett, JB; Dalgleish, AG; Dredge, K1
Corral, LG; Fleming, YW; Stein, B; Zhu, D1

Reviews

5 review(s) available for pomalidomide and Benign Neoplasms

ArticleYear
Discovery of Therapeutic Deubiquitylase Effector Molecules: Current Perspectives.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:7

    Topics: Animals; Catalytic Domain; Drug Design; Drug Screening Assays, Antitumor; Fluorescence Resonance Energy Transfer; Humans; Lenalidomide; Ligands; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Conformation; Thalidomide; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitin-Specific Proteases

2014
Regulatory T cell as a target for cancer therapy.
    Archivum immunologiae et therapiae experimentalis, 2010, Volume: 58, Issue:3

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Humans; Immunotherapy; Lenalidomide; Mice; Models, Animal; Myeloablative Agonists; Neoplasms; T-Lymphocytes, Regulatory; Thalidomide; Vidarabine

2010
Immunomodulatory properties of thalidomide analogs: pomalidomide and lenalidomide, experimental and therapeutic applications.
    Recent patents on endocrine, metabolic & immune drug discovery, 2011, Volume: 5, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Drug Evaluation, Preclinical; Humans; Immunomodulation; Lenalidomide; Neoplasms; Patents as Topic; Thalidomide

2011
The application and biology of immunomodulatory drugs (IMiDs) in cancer.
    Pharmacology & therapeutics, 2012, Volume: 136, Issue:1

    Topics: Humans; Immunologic Factors; Lenalidomide; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Second Primary; Thalidomide

2012
The evolution of thalidomide and its IMiD derivatives as anticancer agents.
    Nature reviews. Cancer, 2004, Volume: 4, Issue:4

    Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents; Antineoplastic Agents; Clinical Trials as Topic; Humans; Lenalidomide; Multiple Myeloma; Neoplasms; T-Lymphocytes; Thalidomide; Tumor Necrosis Factor-alpha

2004

Trials

3 trial(s) available for pomalidomide and Benign Neoplasms

ArticleYear
Use of the Functional Assessment of Cancer Therapy--anemia in persons with myeloproliferative neoplasm-associated myelofibrosis and anemia.
    Clinical therapeutics, 2014, Apr-01, Volume: 36, Issue:4

    Topics: Anemia; Bayes Theorem; Double-Blind Method; Female; Glucocorticoids; Humans; Male; Myeloproliferative Disorders; Neoplasms; Prednisone; Primary Myelofibrosis; Quality of Life; Thalidomide; Treatment Outcome

2014
Phase I trial of pomalidomide given for patients with advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Immunologic Factors; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Thalidomide; Treatment Outcome; Young Adult

2012
Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells.
    Clinical and experimental immunology, 2002, Volume: 130, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Antibodies, Monoclonal; Antigens, CD; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammation; Lenalidomide; Lipopolysaccharides; Lymphocyte Activation; Male; Middle Aged; Neoplasms; Phosphodiesterase Inhibitors; Receptors, Interleukin-2; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Signal Transduction; Solubility; Thalidomide; Tumor Necrosis Factor-alpha

2002

Other Studies

7 other study(ies) available for pomalidomide and Benign Neoplasms

ArticleYear
Discovery of novel BCR-ABL PROTACs based on the cereblon E3 ligase design, synthesis, and biological evaluation.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Animals; Cell Proliferation; Dasatinib; Drug Design; Fusion Proteins, bcr-abl; Half-Life; Humans; K562 Cells; Lenalidomide; Ligands; Mice; Neoplasms; Protein Kinase Inhibitors; Proteolysis; Structure-Activity Relationship; Thalidomide; Transplantation, Heterologous; Ubiquitin-Protein Ligases

2021
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: Cell Line, Tumor; Drug Design; Humans; Neoplasms; Proteolysis; Proto-Oncogene Proteins c-akt

2022
Serendipitous discovery of Class I HDAC inhibitors from rational design of molecular glue degraders targeting HDAC.
    European journal of medicinal chemistry, 2024, Jan-05, Volume: 263

    Topics: Histone Deacetylase Inhibitors; Humans; Neoplasms; Thalidomide

2024
The struggle to do no harm in clinical trials.
    Nature, 2017, 12-21, Volume: 552, Issue:7685

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD19; Child; Clinical Trials as Topic; Drug-Related Side Effects and Adverse Reactions; Humans; Immunotherapy; Inflammation; Lenalidomide; Male; Neoplasms; Nivolumab; Prognosis; Programmed Cell Death 1 Receptor; Risk Management; T-Lymphocytes; Thalidomide; Treatment Outcome; Vidarabine

2017
Pomalidomide Inhibits PD-L1 Induction to Promote Antitumor Immunity.
    Cancer research, 2018, 12-01, Volume: 78, Issue:23

    Topics: Animals; Antineoplastic Agents; B7-H1 Antigen; Cell Line, Tumor; Cytotoxicity, Immunologic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunity; Immunologic Factors; Immunomodulation; Melanoma, Experimental; Mice; Neoplasms; T-Lymphocyte Subsets; Thalidomide

2018
Chiral inversion of the second generation IMiD CC-4047 (ACTIMID ) in human plasma and phosphate-buffered saline.
    Chirality, 2003, May-05, Volume: 15, Issue:4

    Topics: Adjuvants, Immunologic; Antineoplastic Agents; Humans; In Vitro Techniques; Neoplasms; Sodium Chloride; Stereoisomerism; Thalidomide

2003
Immunomodulatory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation.
    Cancer immunology, immunotherapy : CII, 2008, Volume: 57, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coculture Techniques; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Killer Cells, Natural; Lenalidomide; Leukocytes, Mononuclear; Lymphoma, Non-Hodgkin; Male; Neoplasms; Prostatic Neoplasms; Thalidomide

2008