polidocanol and Skin-Neoplasms

Topics: Anemia; Child; Duodenum; Endoscopy, Gastrointestinal; Female; Gastrointestinal Hemorrhage; Gastrointestinal Neoplasms; Humans; Injections, Intralesional; Nevus, Blue; Polidocanol; Sclerosing Solutions; Sclerotherapy; Skin Neoplasms; Treatment Outcome; Vascular Malformations

We report the cases of two women aged 28 and 34 years who presented recurrent glomus tumors of the hand after surgery for marginal resection of the tumor mass. The pathological study of the surgical specimen confirmed the diagnosis of recurrent glomus tumor. Due to the vascular origin of this tumor, sclerotherapy was delivered. The functional outcomes were good with dramatic pain relief within a few days. At 3-year mean follow-up, the cosmetic and functional results were very satisfactory.

Topics: Adult; Female; Finger Injuries; Fingers; Glomus Tumor; Humans; Nail Diseases; Neoplasm Recurrence, Local; Polidocanol; Polyethylene Glycols; Remission Induction; Sclerosing Solutions; Sclerotherapy; Skin Neoplasms; Treatment Outcome

Infantile hemangiomas (IH) are at risk of incomplete regression with remnant permanent sequelae, ranging from passive waiting for spontaneous regression to active systemic administration. The application of traditional therapy involving injection of a sclerosing agent is limited due to the difficulty in achieving cosmetic improvement. This study aimed to explore a new injection method that could not only promote tumor regression but also achieve cosmetic improvement. A total of 122 IH (from 109 children) injected intralesionally with lauromacrogol in the Plastic Surgery Department of Fujian Medical University Union Hospital between 1 January 2012 and 1 June 2019 were enrolled in this study. The mean follow-up time was 2.9 years. Of 122 lesions studied, 111 (91.0%) achieved complete regression, 10 (8.2%) achieved significant regression and one (0.8%) achieved moderate regression. In terms of aesthetic appearance, 70 (57.4%) IH had no sequelae and the A score was 5/5. Twenty-one (17.2%) IH had minimal hyperpigmentation, hypopigmentation or telangiectasia and the A score was 4/5. Thirty-one (25.4%) IH had left mild or relatively obvious sequelae and the A score was 1-3/5. None of the 122 IH involved had rebound growth after terminating the treatment. Hyper- or hypopigmentation gradually faded over time and part of the IH had already returned to normal appearance by the time of long-term follow up. The results indicated that this new type of injection therapy significantly promoted the regression of uncomplicated IH and helped achieve the expected cosmetic appearance.

Topics: Child; Esthetics; Follow-Up Studies; Hemangioma; Humans; Infant; Injections, Intralesional; Polidocanol; Retrospective Studies; Skin Neoplasms; Treatment Outcome

Topics: Adolescent; Anemia, Iron-Deficiency; Blood Transfusion; Capsule Endoscopy; Gastrointestinal Neoplasms; Humans; Ileum; Jejunum; Male; Melena; Nevus, Blue; Polidocanol; Recurrence; Sclerosing Solutions; Single-Balloon Enteroscopy; Skin Neoplasms; Treatment Outcome

Topics: Female; Gastrointestinal Neoplasms; Humans; Injections, Intralesional; Intestinal Neoplasms; Nevus, Blue; Polidocanol; Polyethylene Glycols; Sclerosing Solutions; Skin Neoplasms; Young Adult

Topics: Adult; Humans; Male; Nevus, Blue; Polidocanol; Polyethylene Glycols; Sclerosing Solutions; Sclerotherapy; Skin Neoplasms; Syndrome

Topics: Cryosurgery; Diagnosis, Differential; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Nevus, Blue; Polidocanol; Polyethylene Glycols; Sclerosing Solutions; Sclerotherapy; Skin Neoplasms; Syndrome; Thorax; Tissue Adhesives; Young Adult

While sclerotherapy in chronic venous insufficiency and in hemorrhoids is well established, the use of sclerotherapy for hemangiomas of the skin is widely unknown.. The aim of the study was to analyze the clinical value of sclerotherapy with polidocanol in a larger population.. Over a period of 20 years (1975-1995) we performed sclerotherapy of hemangiomas and vascular malformations in a total of 157 patients. Their ages ranged from 3 months to 75 years. Among these were 87 (55.4%) children and adolescents (up to the age of 18). Sclerotherapy with polidocanol was carried out mostly at monstrous or rapidly growing cavernous hemangiomas mainly localized in the face.. One to three injections was usually sufficient to obtain the sclerosis effect; aesthetically, long-term results were convincing. Severe complications were not observed.. Sclerotherapy of hemangiomas is a relatively simple, effective, and inexpensive method that is a valuable and promising treatment.

Topics: Adolescent; Adult; Child; Female; Follow-Up Studies; Hemangioma; Humans; Infant; Male; Polidocanol; Polyethylene Glycols; Sclerosing Solutions; Sclerotherapy; Skin Neoplasms; Treatment Outcome

We report a case of sudoriparous angioma on the dorsum and plantar aspect of the left foot which increased in size on standing, and which was accompanied by sweating in the overlying epidermis and throbbing pain. The lesion regressed considerably following intravascular injection of 1% aethoxysclerol.

Topics: Child; Female; Foot Diseases; Hemangioma; Humans; Phlebography; Polidocanol; Polyethylene Glycols; Sclerosing Solutions; Skin Neoplasms; Sweating