polidocanol and Gastritis

Bleeding non-neoplastic lesions of the upper gastrointestinal tract, not due to portal hypertension, are a frequent cause of emergency admission. In the present paper we report our retrospective experience in hemostatic injection treatment of these lesions. From May 1990 to May 1994, 164 patients were admitted to our institution for a bleeding gastrointestinal lesion. In 124 cases an ulcer classified according Forrest's criteria was detected. Four patients underwent immediate surgery. The second group of 86 patients (FIIa/FIIb/FIII) were treated conservatively. The third group of 34 patients (FIa/FIb/FIIa) underwent perilesional injection of adrenaline 1:10,000 and polidocanol 1% saline solution during endoscopic examination; 29% (25 pts) of the second group re-bled during the first 72 h vs 8.8% (3 pts) of the third group. The postoperative morbidity in the rebleeding patients was higher in the second group: 38.4% vs 0%. The importance of immediate, inexpensive, and simple hemostatic treatment extended to Forrest IIa lesions is emphasized.

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Duodenal Ulcer; Epinephrine; Female; Gastritis; Gastroscopy; Hemostatic Techniques; Humans; Injections; Male; Middle Aged; Peptic Ulcer Hemorrhage; Polidocanol; Polyethylene Glycols; Retrospective Studies; Sclerosing Solutions; Sclerotherapy; Stomach Ulcer

For a duration of three years, endoscopic hemostasis was carried out in the Department for Gastroenterology at the State Hospital of the Canton of St. Gall on 20 patients suffering from acute upper gastrointestinal hemorrhage. 13 cases were of the hemorrhage type Forest IA, seven cases of the type Forest IB. By way of injecting adrenalin and/or Polidocanol, in all cases an initial hemostasis and in 80% of the cases a definite effect was attained. We judge the injection-method to be a simple, effective and inexpensive way of stopping hemorrhage. This method helps to avoid operating on high-risk patients to stop hemorrhage in the upper gastrointestinal parts.

Topics: Adult; Aged; Aged, 80 and over; Esophagitis; Female; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; Middle Aged; Peptic Ulcer Hemorrhage; Polidocanol; Polyethylene Glycols; Sclerosing Solutions