podophyllotoxin has been researched along with Neoplasms in 223 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 124 (55.61) | 18.7374 |
| 1990's | 15 (6.73) | 18.2507 |
| 2000's | 17 (7.62) | 29.6817 |
| 2010's | 53 (23.77) | 24.3611 |
| 2020's | 14 (6.28) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, X; Shao, L; Wang, S; Zhang, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Kamal, A; Kumar, BA; Kumar, MS; Shankaraiah, N; Suresh, P | 1 |
| Janaki Ramaiah, M; Kamal, A; Kumar, BA; Lavanya, A; Mallareddy, A; Pal-Bhadra, M; Pushpavalli, SN; Raju, P; Sarma, P; Suresh, P; Vinay Gopal, J | 1 |
| Chen, SW; Ding, YL; Huang, WT; Hui, L; Liu, J; Liu, JF | 1 |
| Akula, B; Bharathi, EV; Billa, VK; Cosenza, SC; Gallo, JM; Lv, H; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR | 1 |
| Amewu, RK; Burrell-Saward, H; Chadwick, J; Hussain, A; Janneh, O; Miguel, C; O'Neill, PM; Panda, S; Rinki, R; Vivas, L; Ward, SA | 1 |
| Aksenov, AV; Aksenov, NA; Aksenova, IV; Brenner, AJ; Bryan, BA; Cavazos, DA; Correa, J; De Carvalho, A; Frolova, LV; Johnston, RK; Kiss, R; Kornienko, A; Lefranc, F; Magedov, IV; Mathieu, V; Nguyen, G; Pendleton, AL; Reisenauer, MR; Rogelj, S; Rubin, M; Smirnov, AN | 1 |
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| Jones, AT; Kandil, S; Kariuki, BM; McGuigan, C; Westwell, AD; Wymant, JM | 1 |
| Bahulayan, AK; Kabeer, FA; Madhusoodhanan, AR; Nair, MS; Prakasan, N; Prathapan, R; Rajalekshmi, DS; Varughese, S | 1 |
| Bueno, O; Camarasa, MJ; Díaz, JF; Estévez-Gallego, J; Liekens, S; Noppen, S; Pérez-Pérez, MJ; Priego, EM; Quesada, E; Tobajas, G | 1 |
| Behera, C; Chanda, D; Fatima, K; Gupta, AK; Hasanain, M; Khwaja, S; Kour, A; Luqman, S; Mondhe, DM; Negi, AS; Sarkar, J; Shanker, K; Singh, A | 1 |
| Liu, Y; Xu, Z; Zhao, SJ | 1 |
| Gao, Y; Liu, J; Ma, X; Qu, Y; Wu, L; Zhang, C | 1 |
| Liang, B; Zhou, D | 1 |
| Li, M; Wang, W; Xuan, Y; Zhang, L; Zhang, S; Zhang, W; Zhao, Y; Zhi, D | 1 |
| Chen, H; Li, M; Lin, K; Liu, Z; Ma, P; Sun, J; Zhang, S; Zhang, W; Zhao, Y; Zhen, Y | 1 |
| Ahmed, F; Aktar, A; Bachar, SC; Biswas, B; Fukase, K; Hossain, ME; Mazumder, K; Monjur-Al-Hossain, ASM; Roy, P; Sarkar, KK | 1 |
| Abbaszadeh, H; Mottaghi, S | 1 |
| Al-Omari, B; Calina, D; Cho, WC; Ekiert, H; Jafernik, K; Motyka, S; Sharifi-Rad, J; Szopa, A | 1 |
| Han, J; Hou, Y; Hu, S; Hu, Y; Liu, P; Su, H; Sun, X; Xu, Y; Yang, Y; Zhang, C; Zhang, Z | 1 |
| Fan, ZC; Fu, Y; Guo, N; Hao, T; Liu, Y; Teng, YO; Wei, L; Xiang, C; Yu, P | 1 |
| Ding, ZT; Hu, JM; Jiang, ZH; Kong, QH; Li, HM; Yang, L; Yang, XZ; Zhou, J; Zi, CT | 1 |
| Chaurasiya, B; Chen, D; Li, Y; Shen, Y; Sun, R; Tang, B; Tu, J; Yu, C; Yu, Y; Zu, C | 1 |
| Du, Y; Ismail, M; Ling, L; Qi, J; Yu, H; Zhu, Y | 1 |
| Cong, Y; Li, HM; Li, S; Li, YZ; Qi, Q; Shen, Y; Tang, YJ; Zhang, Y; Zhao, W | 1 |
| Gohar, UF; Jamshed, I; Manea, R; Moga, M; Mukhtar, H; Mushtaq, A; Popovici, B; Shah, Z; Toma, SI; Zia-Ui-Haq, M | 1 |
| Bosch, M; Danyluk, P; Dusyk, T; Elemary, M; Hahn, L; Lim, H; Sabry, W; Stakiw, J | 1 |
| Bombarde, O; Calsou, P; Frit, P; Gomes, B; Gomez, D; Guilbaud, N; Larminat, F; Racca, C | 1 |
| Asiri, AM; Manukumar, HM; Marwani, HM; Qin, HL; Rakesh, KP; Shantharam, CS; Zhang, X | 1 |
| Behbahani, FS; Delpazir, S; Ghodsi, R; Malayeri, SO; Rashidi, R; Tayarani-Najaran, Z | 1 |
| Tang, YJ; Zhang, QY; Zhao, W | 1 |
| Alliot, J; Doris, E; Ducongé, F; Forier, C; Gravel, E; Nguyen, DV; Theodorou, I | 1 |
| Defant, A; Mancini, I | 1 |
| Kamal, A; Kankala, S; Nerella, S; Paidakula, S; Vadde, R | 1 |
| Benham, V; Bernard, JJ; Bernard, MP; Bullard, B; Dexheimer, TS; Liby, KT; Neubig, RR | 1 |
| Kolygin, BA; Kuleva, SA | 1 |
| Kumar, D; Kumari, A; Yadav, R; Yadav, SK | 1 |
| Kou, L; Lee, KH; Liu, YQ; Morris-Natschke, SL; Nan, X; Wang, LT; Wang, MJ; Yang, L; Zhao, XB | 1 |
| Bai, XY; Wang, CH; Wang, CY | 1 |
| Tang, L; Tang, Y; Wang, H; Yuan, Z | 1 |
| Hasinoff, BB; Patel, D; Wu, X; Yadav, AA; Yalowich, JC | 1 |
| Hussaini, SM; Kamal, A; Malik, MS | 1 |
| Ernsting, MJ; Li, SD; Roy, A; Undzys, E | 1 |
| Ali Hussaini, SM; Kamal, A; Rahim, A; Riyaz, S | 1 |
| Allodji, RS; Benabdennebi, A; Chavaudra, J; Dayet, F; de Vathaire, F; Deutsch, E; Diallo, I; Diop, F; Haddy, N; Jackson, A; Labbé, M; Le Deley, MC; Lefkopoulos, D; Llanas, D; Oberlin, O; Rubino, C; Schwartz, B; Veres, C; Vu Bezin, J | 1 |
| Lu, GH; Pang, YJ; Qi, JL; Qiu, HY; Sun, WX; Wang, X; Wang, XM; Wang, ZZ; Yang, YH; Yu, FG; Zhang, YH | 1 |
| Nandagopal, K; Routh, S | 1 |
| Du, Y; He, R; Hou, Y; Ismail, M; Li, X; Ling, L; Yao, C; Zhang, Y | 1 |
| Fliniaux, MA; Lautié, E; Quintero, R; Villarreal, ML | 1 |
| Annereau, JP; Bailly, C; Barret, JM; Brel, V; Delcros, JG; Guilbaud, N; Guminski, Y; Imbert, T; Kruczynski, A; Lansiaux, A; Vispé, S | 1 |
| Du, W; He, Q; Hu, C; Hu, Y; Lou, J; Qian, S; Wang, L; Xu, D; Yang, B | 1 |
| Chanotiya, CS; Darokar, MP; Faridi, U; Gupta, A; Gupta, MM; Kumar, JK; Luqman, S; Negi, AS; Shanker, K; Singh, P; Srivastava, S | 1 |
| Allard, A; Chompret, A; de Vathaire, F; Diallo, I; Haddy, N; Lassalle, M; Le Deley, MC; Lefkopoulos, D; Quiniou, E; Rubino, C; Samsaldin, A | 1 |
| Cao, J; He, Q; Hu, C; Hu, Y; Li, L; Lou, J; Qian, S; Weng, Q; Xu, D; Yang, B; Zhu, D; Zhu, H | 1 |
| Azeeza, S; Bharathi, EV; Kamal, A; Malik, MS; Shetti, RV | 1 |
| Hansch, C; Verma, RP | 1 |
| Dubey, A; Kumar, R; Naik, PK | 1 |
| Fang, JH; Ge, CW; Wang, CN; Wu, ZH; Zhao, Y; Zhu, L | 1 |
| Axelson, M; Fryknäs, M; Girnita, L; Hashemi, J; Jernberg-Wiklund, H; Karimi, M; Larsson, C; Larsson, O; Lui, WO; Rudduck, C; Sulaiman, L; Vasilcanu, D; Weng, WH; Worrall, C | 1 |
| Juvekar, A; Kamal, A; Kumar, BA; Suresh, P; Zingde, S | 1 |
| Alegria, AE; Kumar, A; Kumar, V; Malhotra, SV | 1 |
| Chengniu, W; Chunyan, N; Li, Z; Xiaodong, Z; Yu, Z; Zhonghua, W | 1 |
| Jiang, B; Ma, N; Shi, F; Tu, S; Zeng, XN; Zhang, G | 1 |
| Bailly, C; Ballot, C; Formstecher, P; Jendoubi, M; Jonneaux, A; Kluza, J; Laine, W; Marchetti, P | 1 |
| Dutta, A; Gupta, ML | 1 |
| Imthiajali, S; Kamal, A; Lavanya, A; Mallareddy, A; Pal-Bhadra, M; Pushpavalli, SN; Ramaiah, MJ; Suresh, P | 1 |
| Bailly, C | 1 |
| Joerger, M | 1 |
| Abad, A; Del Olmo, E; Guerrero, E; López-Pérez, JL; Montenegro, G; San Feliciano, A | 1 |
| Aparicio Urtasun, J; Díaz Beveridge, R | 1 |
| SELIGER, H | 2 |
| COLSKY, J; GREENSPAN, EM; SCHOENBACH, EB; SHEAR, MJ | 1 |
| LEITER, J; PARADIS, AD; WARAVDEKAR, VS | 1 |
| BELKIN, M; KLINE, I; LEIGHTON, J; ORR, HC | 1 |
| GEILING, EM; KOCSIS, JJ; WALASZEK, EJ | 1 |
| NEWTON, KA; WESTBURY, G; WHITE, WF | 1 |
| GRAUWILER, J; KALBERER, F; MEIER-RUGE, W | 1 |
| DOWNING, V; HARTWELL, JL; LEITER, J; SHEAR, MJ | 1 |
| GREENSPAN, EM; LEITER, J; SHEAR, MJ | 1 |
| WATERMAN, N | 1 |
| Blokhin, DIu | 1 |
| Gobel, BH | 1 |
| Brambilla, G; Castagna, L; Magagnoli, M; Masci, G; Morenghi, E; Pedicini, V; Poretti, D; Santoro, A | 1 |
| Axelson, M; Girnita, A; Girnita, L; Larsson, C; Larsson, O; Lui, WO; Vasilcanu, D; Vasilcanu, R; Weng, WH | 1 |
| Brooks, SL; Buchanan, GR; Eshelman, DA; Fischbach, L; Harris, TR; Long, ZB; Oeffinger, KC; Tomlinson, GE | 1 |
| Hartmann, JT; Lipp, HP | 1 |
| Axelson, M; Girnita, A; Girnita, L; Larsson, O; Natalishvili, N; Rosengren, L; Sehat, B; Vasilcanu, D; Vasilcanu, R; Yin, S | 1 |
| Li, X; Xu, W | 1 |
| Fliniaux, MA; Fliniaux, O; Hano, C; Lainé, E; Lamblin, F; Mesnard, F | 1 |
| Arnold, AM; Whitehouse, JM | 1 |
| Tatarinov, YS | 1 |
| Jungi, WF | 1 |
| Płuzańska, A; Robak, T | 1 |
| Fer, MF; Greco, FA; Hainsworth, JD; Hande, KR; McKay, CM; Wolff, SN | 1 |
| Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ | 1 |
| Belanger, R; Dennery, JM; Gerin-Lajoie, J; Hopkins, HS; Hugenholtz, H; Montpetit, V; Nundy, D; Prior, J; Richard, MT; Stewart, DJ | 1 |
| de Vries, EG; Meinesz, AF; Mulder, NH; Postmus, PE; Sleijfer, DT; Vriesendorp, R | 1 |
| Etcubanas, E; Evans, W; Hayes, FA; Hutson, P; Sinkule, JA | 1 |
| Greco, FA; Hande, KR; Noone, RM; Wedlund, PJ; Wilkinson, GR; Wolff, SN | 1 |
| Schmoll, H | 1 |
| Fuerst, ML | 1 |
| Eagan, RT | 1 |
| Klastersky, J; Sculier, JP | 1 |
| Bergevin, PR; Bloomfield, CD; Cuttner, J; Ellison, RR; Falkson, G; Holland, JF; Kennedy, BJ; Kung, F; Leone, LA; Nissen, NI; Pajak, TF; Silver, RT; Weiss, RB | 1 |
| Achterrath, W; Niederle, N; Schmoll, HJ | 1 |
| Issell, BF | 1 |
| Cavalli, F | 1 |
| Macbeth, FR | 1 |
| Curry, ME; Issell, BF; Tihon, C | 1 |
| Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA | 1 |
| Aisner, J; Van Echo, DA; Whitacre, M; Wiernik, PH | 1 |
| Dicato, M | 1 |
| Bamberg, M; Holfeld, H | 1 |
| Creagan, ET; Eagan, RT; Kvols, LK | 1 |
| Antman, K; Canellos, G; Karp, G | 1 |
| Schulz, JJ; Speckhart, VJ; Spremulli, E; Wampler, GL | 1 |
| Dercksen, MW; Dirkson, MK; Gerritsen, WR; Pinedo, HM; Rodenhuis, S; Schaasberg, WP; Slaper-Cortenbach, IC; van der Schoot, CE; von dem Borne, AE | 1 |
| Sinha, BK | 1 |
| Bendix, G; Bjelle, A; Holmberg, E | 1 |
| D'Incalci, M; De Fusco, M; Gentili, D; Reichert, S; Zucchetti, M | 1 |
| D'Incalci, M; De Fusco, M; Fröhlich, A; Reichert, S; Sessa, C; Zucchetti, M | 1 |
| Kobayashi, K; Ratain, MJ | 1 |
| Bendix, G; Bjelle, A | 1 |
| Ager, S; Baglin, TP; Barker, P; Bass, G; Bloxham, DM; Boraks, PA; Hood, IM; Jestice, HK; Johnson, D; Mahendra, P; Marcus, RE; Scott, MA | 1 |
| Cavalli, F; D'Incalci, M; De Fusco, M; de Jong, J; Hanauske, A; Kaeser-Fröhlich, A; Pagani, O; Sessa, C; Zucchetti, M | 1 |
| Burris, HA; Muggia, FM | 1 |
| Hanauske, AR; Kaeser-Fröhlich, A; Rassmann, I; Rastetter, J; Schilling, T; Schrödel, H; Zucchetti, M | 1 |
| Devereux, S; Goldstone, AH; Leverett, D; Linch, DC; Peniket, AJ; Perry, AR; Sullivan, AM; Watts, MJ; Williams, CD | 1 |
| Blair, IA; Cheung, NK; Felix, CA; Lange, BJ; Lovett, BD; Nowell, PC; Rebbeck, TR; Walker, AH; Williams, TM; Winick, NJ | 1 |
| Chao, Y; Chen, LL; Chen, LT; Chen, MH; Huang, TS; Lee, CC; Shu, CH; Whang-Peng, J; Yuan, CC | 1 |
| Dutcher, JP; Marcoullis, G; Novik, Y; O'Boyle, K; Secco, C; Wiernik, PH | 1 |
| Boddy, AV; Dick, GS; Estlin, EJ; Griffin, MJ; Hale, JP; Little, MA; Morland, B; Parry, A; Pearson, AD; Price, E; Veal, GJ; Welbank, H; Yule, SM | 1 |
| Markman, M; Zanotti, KM | 1 |
| Falkson, G; Falkson, HC; van den Bergh, JA; van der Merwe, AM; van Dyk, JJ; van Eden, EB | 1 |
| Beckmann, C; Flury, R; Frei, P; Holdener, E; Jungi, WF; Senn, HJ | 1 |
| Hansen, HH; Lau, ME; Nissen, NI; Pedersen, H | 1 |
| Bleyer, WA; Chard, RL; Hammond, D; Krivit, W | 1 |
| Crooke, ST; Issell, BF | 1 |
| Arnold, AM | 1 |
| Crooke, ST; Gutierrez, ML | 1 |
| Cox, PJ; Farmer, PB | 1 |
| Smythies, JR | 1 |
| Brunner, KW; Cavalli, F; Ryssel, HJ; Sonntag, RW | 1 |
| Pohlschmidt, L; Trüb, CL | 1 |
| Carter, SK; Livingston, RB | 1 |
| Allen, LM; Creaven, PJ | 3 |
| Amiel, JL; Mathé, G; Misset, JL; Oldham, R; Pouillart, P; Schwarzenberg, L; Weiner, R | 1 |
| Donsimoni, R; Gerota, J; Gumus, Y; Hingh, B; Lam, Y; Lotz, JP; Machover, D; Malassagne, B; Marsiglia, H; Tulliez, M | 1 |
| Carde, P; Ganem, G; Gouyette, A | 1 |
| Bugat, R; Canal, P; Chatelut, E; Chevreau, C; De Forni, M; Houin, G | 1 |
| Crom, WR; Evans, WE; Madden, T; Petros, WP; Relling, MV; Rodman, JH; Sunderland, M | 1 |
| McVie, G; Muggia, FM | 1 |
| Long, BH; Stringfellow, DA | 1 |
| Kimura, K; Niitani, H; Yamada, K | 1 |
| Cummings, J; Cunningham, D; Forrest, GJ; McTaggart, L; Soukop, M; Stuart, JF | 1 |
| Lysholm, J; Weitoft, T | 1 |
| Cummings, J; Cunningham, D; Forrest, GJ; Gilchrist, NL; Soukop, M | 1 |
| de Vries, EG; Mulder, NH; Postmus, PE; Sleijfer, DT; Vriesendorp, R; Willemse, PH | 1 |
| Maroun, JA; Nundy, D; Prior, J; Stewart, DJ; Tetreault, L | 1 |
| Hashimoto, S; Kano, A; Kawamoto, K; Konno, K; Sakata, Y; Sato, S; Takahashi, H; Wakui, A; Yokoyama, M; Yoshida, Y | 1 |
| Gouyette, A; Hartmann, O; Pico, JL | 1 |
| Schoental, R | 2 |
| Larsen, V; Nissen, NI; Pedersen, H; Thomsen, K | 1 |
| COHEN, W; FRANK, SB | 1 |
| FISCHER, R | 1 |
| WARAVDEKAR, VS | 1 |
| HUBACHER, O | 4 |
| GOLDENBERG, DM | 1 |
| DESTRO, G | 2 |
| DOGLIOTTI, GC | 1 |
| KELLNER, B; SUGAR, J | 1 |
| DEJAGER, ME; FALKSON, G | 1 |
| FALKSON, G; SCHULZ, EJ | 1 |
| KAYMAKCALAN, S | 1 |
| CHEVALIER, P; DECHEVEZ, C; DROCHMANS, A; KENIS, Y; MINET, P; STRYCKMANS, P | 1 |
| AQUILINI, E | 1 |
| FRIDRICH, R; ZDANSKY, E | 1 |
| BERNHARDT, H; DAWSON, DF; DUCKWORTH, JK; YOUNG, JM | 1 |
| MASSEI, V; MITI, L | 1 |
| FRIDRICH, R | 1 |
| ECKMANN, L | 1 |
| GUTH, EP; LORAN, MR | 1 |
| GARRET, HD; SMITH, LM | 1 |
| HOLLINGSWORTH, JB; KOHLMOOS, HW; McNAUGHT, RC | 1 |
| Chakravorty, RC; Mukerji, B; Sarkar, SK; Sen, S | 1 |
| Paeschke, KD; Pohl, J | 1 |
| Grewal, TS; Rastogi, DC; Sachdev, DL; Samual, KC | 1 |
| Amiel, JL; Beyer, HP; de Vassal, F; Fajbisowicz, S; Hayat, M; Jasmin, C; Mathé, G; Pouillart, P; Schneider, M; Schwarzenberg, L; Weiner, R | 1 |
| Dombernowsky, P; Larsen, V; Nissen, NI | 1 |
| van Os, FH | 1 |
| Seidenglanz, G | 1 |
| Hansen, HH; Muggia, FM; Selawry, OS | 1 |
| Heckmann, U | 1 |
| Clément, F | 1 |
| Fanchamps, A | 1 |
| Motti, VJ | 1 |
| Diefenthaeler, E; Herter, NT | 1 |
| Schärtl, W | 1 |
| Bosnar, M; Krieg, R; Ringleb, D; Sauer, D; Steckenmesser, R | 1 |
| Furue, H; Hattori, T; Kubo, A; Nakao, I; Yamana, T | 1 |
| Furue, H; Hattori, T; Koizumi, H; Nishi, I; Yokoyama, T | 1 |
| Biswas, S; Datta, H | 1 |
| Messmer, B | 1 |
| Hironaka, T; Kitagawa, S; Motoyama, Y; Nishimura, K; Teramura, Y | 1 |
| Lipozencić, M; Padovan, I | 1 |
| Busch, W; Goldschmidt, F | 1 |
| Lipozencić, M; Padovan, I; Sipus, N | 1 |
| Bîrzu, I | 1 |
43 review(s) available for podophyllotoxin and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2019 |
A Review on Mechanistic Insight of Plant Derived Anticancer Bioactive Phytocompounds and Their Structure Activity Relationship.
Topics: Antineoplastic Agents; Humans; Neoplasms; Plants; Podophyllotoxin; Structure-Activity Relationship | 2022 |
A comprehensive insight into the antineoplastic activities and molecular mechanisms of deoxypodophyllotoxin: Recent trends, challenges, and future outlook.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Drugs, Chinese Herbal; Humans; Lignans; Neoplasms; Phosphatidylinositol 3-Kinases; Podophyllotoxin | 2022 |
Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy.
Topics: Antineoplastic Agents; Antiviral Agents; Humans; Lignans; Neoplasms; Podophyllotoxin | 2023 |
Challenges and potential for improving the druggability of podophyllotoxin-derived drugs in cancer chemotherapy.
Topics: Antineoplastic Agents; Drug Design; Humans; Neoplasms; Podophyllotoxin | 2021 |
Podophyllotoxin: History, Recent Advances and Future Prospects.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; COVID-19 Drug Treatment; Cytokine Release Syndrome; Drug Discovery; Drug Repositioning; Humans; Neoplasms; Podophyllotoxin; Podophyllum | 2021 |
Podophyllotoxin derivatives as an excellent anticancer aspirant for future chemotherapy: A key current imminent needs.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neoplasms; Podophyllotoxin; Structure-Activity Relationship | 2018 |
[Long-term consequences of anticancer therapy in children].
Topics: Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Chemotherapy, Adjuvant; Child; Humans; Iatrogenic Disease; Metals, Heavy; Neoplasms; Podophyllotoxin; Radiotherapy Dosage; Radiotherapy, Adjuvant; Surgical Procedures, Operative; Time Factors | 2012 |
Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development.
Topics: Alkaloids; Amphibian Venoms; Animals; Antineoplastic Agents, Phytogenic; Berberine; Diterpenes; Drug Combinations; Drug Discovery; Drugs, Chinese Herbal; Epoxy Compounds; Flavonoids; Humans; Matrines; Medicine, Chinese Traditional; Molecular Conformation; Molecular Targeted Therapy; Neoplasms; Phenanthrenes; Plants, Medicinal; Podophyllotoxin; Quinolizines | 2014 |
Recent developments towards podophyllotoxin congeners as potential apoptosis inducers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Humans; Molecular Structure; Neoplasms; Podophyllotoxin | 2015 |
Podophyllotoxin derivatives: a patent review (2012 - 2014).
Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Neoplasms; Patents as Topic; Podophyllotoxin | 2015 |
Patent Survey of Resveratrol, Taxol, Podophyllotoxin, Withanolides and Their Derivatives Used in Anticancer Therapy.
Topics: Humans; Neoplasms; Paclitaxel; Patents as Topic; Podophyllotoxin; Resveratrol; Stilbenes; Withanolides | 2017 |
Search for new and novel chemotherapeutics for the treatment of human malignancies.
Topics: Antineoplastic Agents; Benzodiazepines; Benzothiadiazines; Humans; Naphthalimides; Neoplasms; Podophyllotoxin; Pyrimidines; Thiones | 2010 |
Synthetic and application perspectives of azapodophyllotoxins: alternative scaffolds of podophyllotoxin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chemistry Techniques, Synthetic; Humans; Neoplasms; Podophyllotoxin; Podophyllum | 2011 |
Stress-mediated adaptive response leading to genetic diversity and instability in metabolite contents of high medicinal value: an overview on Podophyllum hexandrum.
Topics: Adaptation, Biological; Antineoplastic Agents; Biotechnology; Flavonoids; Genetic Variation; Humans; Neoplasms; Podophyllotoxin; Podophyllum; Radiation-Protective Agents; Stress, Physiological | 2011 |
Contemporary challenges in the design of topoisomerase II inhibitors for cancer chemotherapy.
Topics: Animals; Biological Products; Cell Line, Tumor; DNA Topoisomerases, Type II; Drug Design; Humans; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors | 2012 |
[Therapy-related acute leukaemia and myelodysplastic syndrome].
Topics: Acute Disease; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Bone Marrow Transplantation; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Second Primary; Palliative Care; Podophyllotoxin; Prognosis | 2003 |
[The multidrug tumor cell resistance phenotype caused by the impaired cell death program].
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Disease Progression; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, p53; Humans; Mitoxantrone; Neoplasms; Phenotype; Podophyllotoxin; Radiation Tolerance; Tumor Cells, Cultured | 2004 |
Chemotherapy-induced hypersensitivity reactions.
Topics: Antineoplastic Agents; Asparagine; Drug Hypersensitivity; Humans; Neoplasms; Oncology Nursing; Platinum Compounds; Podophyllotoxin; Risk Assessment; Risk Factors; Taxoids | 2005 |
Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Enzyme Inhibitors; Humans; Neoplasms; Podophyllotoxin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2006 |
Recent patents therapeutic agents for cancer.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Humans; Neoplasms; Organoplatinum Compounds; Patents as Topic; Podophyllotoxin; Taxoids | 2006 |
[Interest of lignans in prevention and treatment of cancers].
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Humans; Lignans; Neoplasms; Phytoestrogens; Podophyllotoxin | 2008 |
Teniposide: a review of 12 years of experience.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide | 1984 |
Review of etoposide single-agent activity.
Topics: Animals; Drug Administration Schedule; Etoposide; Female; Humans; Male; Neoplasms; Podophyllotoxin | 1982 |
The podophyllotoxin derivatives VP16-213 and VM26.
Topics: Animals; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
VP16-213 (etoposide). A critical review of its activity.
Topics: Drug Evaluation; Etoposide; Humans; Neoplasms; Podophyllotoxin; Research Design | 1982 |
VM26: phase I and II studies.
Topics: Drug Evaluation; Humans; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
Topoisomerase inhibitors. A review of their therapeutic potential in cancer.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Irinotecan; Neoplasms; Podophyllotoxin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan | 1995 |
Pharmacodynamics and long-term toxicity of etoposide.
Topics: Child; Etoposide; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Neoplasms; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Testicular Neoplasms | 1994 |
Peripheral blood progenitor cell transplantation: a single centre experience comparing two mobilisation regimens in 67 patients.
Topics: Adolescent; Adult; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmustine; Cell Movement; Colony-Forming Units Assay; Cyclophosphamide; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Kidney Diseases; Leukapheresis; Leukocyte Count; Male; Melphalan; Middle Aged; Neoplasms; Podophyllotoxin; Retrospective Studies; Thiotepa; Transplantation Conditioning | 1996 |
Clinical development of topoisomerase-interactive drugs.
Topics: Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Neoplasms; Podophyllotoxin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan | 1994 |
20th-century advances in drug therapy in oncology--Part. II.
Topics: Antineoplastic Agents; Bridged-Ring Compounds; Camptothecin; Drug Therapy; Humans; Neoplasms; Podophyllotoxin; Taxoids; Topoisomerase I Inhibitors; Vinca Alkaloids | 2000 |
Prevention and management of antineoplastic-induced hypersensitivity reactions.
Topics: Antineoplastic Agents; Asparaginase; Docetaxel; Drug Hypersensitivity; Humans; Neoplasms; Organoplatinum Compounds; Paclitaxel; Podophyllotoxin; Taxoids | 2001 |
Etoposide (VP-16-213).
Topics: Adult; Animals; Bone Marrow; Cell Cycle; Child; Digestive System; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Rats | 1979 |
Podophyllotoxin derivative VP 16-213.
Topics: Animals; Bronchial Neoplasms; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Etoposide; Humans; In Vitro Techniques; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Lymphoma; Mice; Neoplasms; Podophyllotoxin; Rabbits; Rats; Sarcoma | 1979 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Towards selectivity? Approaches to the design of new anti-tumour agents--II.
Topics: Altretamine; Amino Acids; Antineoplastic Agents; Carbohydrates; Chelating Agents; Colchicine; Coloring Agents; Dacarbazine; Daunorubicin; Doxorubicin; Drug Interactions; Ellipticines; Folic Acid Antagonists; Heart Diseases; Humans; Lectins; Neoplasms; Nitrosourea Compounds; Peptide Hydrolases; Podophyllotoxin; Polymers; Structure-Activity Relationship | 1977 |
Plant products in cancer chemotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Lymphoma; Neoplasms; Phytotherapy; Plants, Medicinal; Podophyllotoxin; Vinblastine; Vinca Alkaloids; Vincristine | 1976 |
[Prolonged intravenous infusion chemotherapy. General review of theoretical bases and results].
Topics: Antineoplastic Agents; Bleomycin; Cell Cycle; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Humans; Infusions, Parenteral; Neoplasms; Podophyllotoxin; Time Factors; Vinca Alkaloids | 1985 |
Clinical pharmacology of cancer chemotherapy in children.
Topics: Adult; Age Factors; Antibiotics, Antineoplastic; Child; Child, Preschool; Humans; Neoplasms; Phosphoramide Mustards; Podophyllotoxin; Vinca Alkaloids | 1989 |
[Plants with cytostatic effect].
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine | 1970 |
[Chemotherapy of malignant tumors. 44].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Androgens; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Azirines; Carbamates; Colchicine; Dichlorodiphenyldichloroethane; Esters; Estrogens; Ethers, Cyclic; Ethylamines; Excitatory Amino Acid Antagonists; Folic Acid Antagonists; Heterocyclic Compounds; Hormones; Hydrazines; Mannitol; Neoplasms; Phytotherapy; Pipobroman; Plants, Medicinal; Plants, Toxic; Podophyllum; Purines; Pyrimidines; Sulfonic Acids; Triazines; Vinblastine; Vincristine | 1970 |
22 trial(s) available for podophyllotoxin and Neoplasms
| Article | Year |
|---|---|
[New antineoplastic drugs of the podophyllotoxin derivative group].
Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1983 |
Teniposide: a review of 12 years of experience.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide | 1984 |
Clinical trial of VP 16--213 (NSC 141540) I.V. twice weekly in advanced neoplastic disease: a study by the Cancer and Leukemia Group B.
Topics: Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Female; Humans; Injections, Intravenous; Male; Neoplasms; Podophyllotoxin; Remission, Spontaneous | 1980 |
[Etoposide VP 16--213)--a podophyllotoxinderivative with high antitumor activity (author's transl)].
Topics: Animals; Chemical Phenomena; Chemistry; Clinical Trials as Topic; DNA, Neoplasm; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; RNA, Neoplasm | 1981 |
High-performance liquid chromatographic assay for the determination of the novel etoposide derivative dimethylaminoetoposide (NK611) and its metabolites in urine of cancer patients.
Topics: Administration, Oral; Antineoplastic Agents; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Neoplasms; Podophyllotoxin; Quality Control; Spectrophotometry, Ultraviolet | 1995 |
Peripheral blood progenitor cell transplantation: a single centre experience comparing two mobilisation regimens in 67 patients.
Topics: Adolescent; Adult; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carmustine; Cell Movement; Colony-Forming Units Assay; Cyclophosphamide; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Kidney Diseases; Leukapheresis; Leukocyte Count; Male; Melphalan; Middle Aged; Neoplasms; Podophyllotoxin; Retrospective Studies; Thiotepa; Transplantation Conditioning | 1996 |
Clinical and pharmacokinetic study of oral NK611, a new podophyllotoxin derivative.
Topics: Administration, Oral; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neutropenia; Podophyllotoxin; Thrombocytopenia | 1996 |
Clinical and pharmacokinetic phase I trial of oral dimethylaminoetoposide (NK611) administered for 21 days every 35 days.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Cell Count; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Neutropenia; Podophyllotoxin | 1996 |
A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin.
Topics: Adolescent; Antineoplastic Agents; Area Under Curve; Child; Child, Preschool; Cholesterol; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Infant; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Liposomes; Male; Neoplasms; Podophyllin; Podophyllotoxin; Time Factors; Triglycerides | 2001 |
Phase I trial of a new form of an oral administration of VP-16-213.
Topics: Administration, Oral; Adult; Aged; Capsules; Clinical Trials as Topic; Drug Evaluation; Etoposide; Female; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasms; Podophyllotoxin | 1979 |
Phase II study of VM-26 in acute leukemia, neuroblastoma, and other refractory childhood malignancies: a report from the Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Neoplasms; Neuroblastoma; Podophyllotoxin; Remission, Spontaneous; Teniposide | 1979 |
Podophyllotoxin derivative VP 16-213.
Topics: Animals; Bronchial Neoplasms; Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Etoposide; Humans; In Vitro Techniques; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Lymphoma; Mice; Neoplasms; Podophyllotoxin; Rabbits; Rats; Sarcoma | 1979 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Phase I-II study of two consecutive courses of high-dose epipodophyllotoxin, ifosfamide, and carboplatin with autologous bone marrow transplantation for treatment of adult patients with solid tumors.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Central Nervous System Diseases; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation; Female; Hematologic Diseases; Humans; Ifosfamide; Male; Middle Aged; Neoplasms; Podophyllotoxin; Pregnancy; Transplantation, Autologous | 1991 |
[Prolonged intravenous infusion chemotherapy. General review of theoretical bases and results].
Topics: Antineoplastic Agents; Bleomycin; Cell Cycle; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Humans; Infusions, Parenteral; Neoplasms; Podophyllotoxin; Time Factors; Vinca Alkaloids | 1985 |
[Phase I clinical study of NK 171 (etoposide)].
Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Podophyllotoxin | 1985 |
Bioavailability, pharmacokinetics, and clinical effects of an oral preparation of etoposide.
Topics: Administration, Oral; Biological Availability; Capsules; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Granulocytes; Half-Life; Humans; Infusions, Parenteral; Kinetics; Leukocyte Count; Nausea; Neoplasms; Platelet Count; Podophyllotoxin; Random Allocation | 1985 |
Epipodophyllotoxin VP 16213 in treatment of acute leukaemias, haematosarcomas, and solid tumours.
Topics: Adult; Aged; Agranulocytosis; Alopecia; Antineoplastic Agents; Female; Glycosides; Hodgkin Disease; Humans; Lactones; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Nausea; Neoplasms; Neutrophils; Podophyllotoxin; Remission, Spontaneous; Thrombocytopenia; Vomiting | 1973 |
Phase I clinical trial of a new antitumor agent, 4'-demethylepipodophyllotoxin 9-(4,6-O-ethylidene- -D-glucopyranoside) (NSC-141540; VP-16-213).
Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Glycosides; Haplorhini; Hemoglobins; Hodgkin Disease; Humans; Lethal Dose 50; Macaca; Mice; Neoplasm Transplantation; Neoplasms; Podophyllotoxin; Remission, Spontaneous; Solubility; Time Factors; Transplantation, Homologous | 1972 |
Clinical screening of epipodophyllotoxin VM26 in malignant lymphomas and solid tumours.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Alopecia; Anemia, Aplastic; Antineoplastic Agents; Blood Platelet Disorders; Child; Clinical Trials as Topic; Female; Gastrointestinal Diseases; Glycosides; Hematopoiesis; Hodgkin Disease; Humans; Lactones; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Remission, Spontaneous; Thiophenes; Urinary Bladder Neoplasms | 1972 |
Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819).
Topics: Aged; Antineoplastic Agents; Astrocytoma; Clinical Trials as Topic; Esophageal Neoplasms; Evaluation Studies as Topic; Fibroblasts; Glycosides; Humans; Hypotension; Lactones; Leiomyosarcoma; Leukopenia; Liver Neoplasms; Lung Neoplasms; Melanoma; Middle Aged; Mitosis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Structure-Activity Relationship; Thiophenes; Thrombocytopenia | 1971 |
[5-year results of combined treatment with the cobalt bomb and the cytostatic preparation SP-G and SP-I (Sandoz)].
Topics: Antineoplastic Agents; Cobalt Isotopes; Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1965 |
163 other study(ies) available for podophyllotoxin and Neoplasms
| Article | Year |
|---|---|
CHMIS-C: a comprehensive herbal medicine information system for cancer.
Topics: Antineoplastic Agents, Phytogenic; Databases, Factual; Internet; National Institutes of Health (U.S.); Neoplasms; Phytotherapy; Plant Preparations; United States; United States Food and Drug Administration | 2005 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
Topics: Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Chlorides; DNA Topoisomerases, Type II; Halogenation; Humans; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Zirconium | 2011 |
Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Comet Assay; DNA; DNA Damage; Drug Screening Assays, Antitumor; Etoposide; Humans; Neoplasms; Podophyllotoxin | 2011 |
Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Drugs, Chinese Herbal; Enzyme Activation; Fluorouracil; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Neoplasms; Podophyllotoxin | 2012 |
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood-Brain Barrier; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Design; Drug Resistance, Neoplasm; HCT116 Cells; Humans; K562 Cells; MCF-7 Cells; Mice; Mice, Nude; Microtubules; Neoplasms; Polymerization; Sulfonamides; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
Topics: Antimalarials; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Dimerization; Humans; Malaria, Falciparum; Neoplasms; Plasmodium falciparum; Tetraoxanes | 2013 |
Activity of 2-aryl-2-(3-indolyl)acetohydroxamates against drug-resistant cancer cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cells, Cultured; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fibroblasts; Humans; Hydroxamic Acids; Indoles; Neoplasms; Neoplastic Stem Cells; Structure-Activity Relationship | 2015 |
Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Humans; MCF-7 Cells; Microtubules; Molecular Docking Simulation; Neoplasms; Podophyllotoxin; Stereoisomerism; Tubulin; Tubulin Modulators | 2016 |
Anticancer activity studies of cubebin isolated from Piper cubeba and its synthetic derivatives.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Humans; Lignans; Models, Molecular; Neoplasms; Piper; Seeds | 2016 |
Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity.
Topics: Animals; Antineoplastic Agents; Benzodioxoles; Binding Sites; Biomimetics; Cell Line; Cell Proliferation; Chalcones; Drug Design; Endothelial Cells; Humans; Neoplasms; Protein Conformation; Tubulin; Tubulin Modulators | 2018 |
Antiproliferative efficacy of curcumin mimics through microtubule destabilization.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Microtubules; Neoplasms | 2018 |
Synthesis and biological evaluation of NQO1-activated prodrugs of podophyllotoxin as antitumor agents.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Humans; Mice; Mice, Nude; Molecular Docking Simulation; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Podophyllotoxin; Prodrugs; Rats; Transplantation, Heterologous | 2020 |
ROS-Activated homodimeric podophyllotoxin nanomedicine with self-accelerating drug release for efficient cancer eradication.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Liberation; Drug Stability; Female; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Mice, Nude; NAD(P)H Dehydrogenase (Quinone); NADP; Nanoparticles; Neoplasms; Podophyllotoxin; Poloxamer; Polymers; Prodrugs; Reactive Oxygen Species; Tumor Microenvironment; Vitamin K 3; Xenograft Model Antitumor Assays | 2021 |
pH-sensitive hyaluronic acid-targeted prodrug micelles constructed via a one-step reaction for enhanced chemotherapy.
Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Micelles; Neoplasms; Podophyllotoxin; Prodrugs | 2022 |
pH/reduction dual-responsive hyaluronic acid-podophyllotoxin prodrug micelles for tumor targeted delivery.
Topics: Drug Delivery Systems; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Micelles; Neoplasms; Podophyllotoxin; Prodrugs | 2022 |
Discovery of Podofilox as a Potent cGAMP-STING Signaling Enhancer with Antitumor Activity.
Topics: Animals; Immunity, Innate; Membrane Proteins; Mice; Neoplasms; Podophyllotoxin; Signal Transduction | 2023 |
Podophyllotoxin-loaded PEGylated E-selectin peptide conjugate targeted cancer site to enhance tumor inhibition and reduce side effect.
Topics: Drug-Related Side Effects and Adverse Reactions; E-Selectin; Human Umbilical Vein Endothelial Cells; Humans; Ligands; Neoplasms; Peptides; Podophyllotoxin; Polyethylene Glycols; Tumor Microenvironment | 2023 |
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Glucosides; Humans; Inhibitory Concentration 50; Neoplasms; Podophyllotoxin; Structure-Activity Relationship | 2019 |
Highly loaded deoxypodophyllotoxin nano-formulation delivered by methoxy polyethylene glycol-block-poly (D,L-lactide) micelles for efficient cancer therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Delivery Systems; Drugs, Chinese Herbal; Freeze Drying; Humans; Male; Mice; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Particle Size; Podophyllotoxin; Polyesters; Polyethylene Glycols; Time Factors; Tissue Distribution | 2020 |
Synthetic dimeric-drug phospholipid: a versatile liposomal platform for cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Female; Humans; Liposomes; Mice, Inbred BALB C; Neoplasms; Phosphatidylcholines; Podophyllotoxin; Prodrugs; Xenograft Model Antitumor Assays | 2020 |
BeEAM conditioning regimen is a safe, efficacious and economical alternative to BEAM chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Neoplasms; Outcome Assessment, Health Care; Podophyllotoxin; Transplantation Conditioning | 2021 |
The DNA-Binding Polyamine Moiety in the Vectorized DNA Topoisomerase II Inhibitor F14512 Alters Reparability of the Consequent Enzyme-Linked DNA Double-Strand Breaks.
Topics: Apoptosis; BRCA1 Protein; Chromatin; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; Genetic Vectors; Humans; Neoplasms; Podophyllotoxin; Polyamines; Rad51 Recombinase; Topoisomerase II Inhibitors | 2017 |
Synthesis and biological evaluation of benzo[b]furo[3,4-e][1,4]diazepin-1-one derivatives as anti-cancer agents.
Topics: Antineoplastic Agents; Apoptosis; Benzodiazepinones; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Podophyllotoxin; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2018 |
Discover the leading compound of 4β-S-(5-fluorobenzoxazole)-4-deoxy-4'-demethylepipodophyllotoxin with millimolar-potency toxicity by modifying the molecule structure of 4'-demethylepipodophyllotoxin.
Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Drug Design; Halogenation; Hep G2 Cells; Humans; Models, Molecular; Neoplasms; Oxazoles; Podophyllotoxin | 2018 |
Tumor targeted micellar nanocarriers assembled from epipodophyllotoxin-based amphiphiles.
Topics: Animals; Cell Line, Tumor; Drug Carriers; Humans; Mice; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Podophyllotoxin; Polyethylene Glycols; Spectroscopy, Near-Infrared; Transplantation, Heterologous | 2019 |
Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Neoplasms; Podophyllotoxin; Pyridines; Quinolines; rho-Associated Kinases; Stilbenes; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators | 2019 |
Design and synthesis of 4β-Acetamidobenzofuranone-podophyllotoxin hybrids and their anti-cancer evaluation.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Podophyllotoxin; Structure-Activity Relationship | 2019 |
Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay.
Topics: Animals; Antineoplastic Agents; Cell Culture Techniques; Cell Proliferation; Cell Transformation, Neoplastic; Drug Screening Assays, Antitumor; Fibroblast Growth Factor 2; Fibroblasts; Fluvastatin; High-Throughput Screening Assays; Humans; Mice; Models, Biological; Neoplasms; Obesity; Podophyllotoxin; Skin | 2019 |
Encapsulation of podophyllotoxin and etoposide in biodegradable poly-D,L-lactide nanoparticles improved their anticancer activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; CHO Cells; Cricetinae; Cricetulus; Delayed-Action Preparations; Drug Screening Assays, Antitumor; Etoposide; Humans; Nanoparticles; Neoplasms; Podophyllotoxin; Polyesters | 2014 |
Toward synthesis of third-generation spin-labeled podophyllotoxin derivatives using isocyanide multicomponent reactions.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cyanides; Drug Screening Assays, Antitumor; Etoposide; Humans; Neoplasms; Podophyllotoxin; Spin Labels; Structure-Activity Relationship | 2014 |
SAR analysis and biological studies of synthesized podophyllum derivates obtained by N linkage modification at C-4 position.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Neoplasms; Podophyllotoxin; Podophyllum peltatum; Structure-Activity Relationship; Tubulin Modulators | 2014 |
Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia; Molecular Docking Simulation; Mustard Compounds; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors | 2014 |
A highly tumor-targeted nanoparticle of podophyllotoxin penetrated tumor core and regressed multidrug resistant tumors.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Maximum Tolerated Dose; Mice; Nanoparticles; Neoplasm Transplantation; Neoplasms; Particle Size; Podophyllotoxin; Polyethylene Glycols | 2015 |
Risk of Subsequent Leukemia After a Solid Tumor in Childhood: Impact of Bone Marrow Radiation Therapy and Chemotherapy.
Topics: Adolescent; Analysis of Variance; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Bone Marrow; Case-Control Studies; Child; Child, Preschool; Confidence Intervals; Female; Humans; Infant; Leukemia; Leukemia, Radiation-Induced; Male; Neoplasms; Neoplasms, Second Primary; Odds Ratio; Platinum Compounds; Podophyllotoxin; Radiation Dosage | 2015 |
Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Neoplasms; Oxadiazoles; Podophyllotoxin; Quantitative Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2017 |
Assembled liposomes of dual podophyllotoxin phospholipid: preparation, characterization and in vivo anticancer activity.
Topics: Antineoplastic Agents; Cell Proliferation; HeLa Cells; Humans; Liposomes; MCF-7 Cells; Neoplasms; Phospholipids; Podophyllotoxin | 2017 |
Selection methodology with scoring system: application to Mexican plants producing podophyllotoxin related lignans.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Humans; Lignans; Mexico; Neoplasms; Phytotherapy; Plant Extracts; Plants, Medicinal; Podophyllotoxin; Research Design | 2008 |
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.
Topics: Animals; Binding, Competitive; Biogenic Polyamines; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Delivery Systems; Etoposide; Female; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2008 |
Novel 4 beta-anilino-podophyllotoxin derivatives: design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents.
Topics: Aniline Compounds; Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; Humans; Mice; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2010 |
Design and synthesis of C-ring lactone- and lactam-based podophyllotoxin analogues as anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Erythrocytes; Hemolysis; Humans; Lactams; Lactones; Molecular Structure; Neoplasms; Podophyllotoxin | 2010 |
Role of radiation dose in the risk of secondary leukemia after a solid tumor in childhood treated between 1980 and 1999.
Topics: Adolescent; Algorithms; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bone Marrow; Case-Control Studies; Child; Child, Preschool; Dose-Response Relationship, Radiation; Female; France; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Leukemia, Radiation-Induced; Likelihood Functions; Male; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasms; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Radiotherapy Dosage; Risk Assessment | 2010 |
5k, a novel β-O-demethyl-epipodophyllotoxin analogue, inhibits the proliferation of cancer cells in vitro and in vivo via the induction of G2 arrest and apoptosis.
Topics: Animals; Apoptosis; Caffeine; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; G2 Phase Cell Cycle Checkpoints; Herpes Simplex Virus Protein Vmw65; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Podophyllotoxin; Proto-Oncogene Proteins c-bcl-2; Topoisomerase II Inhibitors | 2011 |
A QSAR study on the cytotoxicity of podophyllotoxin analogues against various cancer cell lines.
Topics: Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; K562 Cells; Molecular Conformation; Neoplasms; Podophyllotoxin; Quantitative Structure-Activity Relationship; Stereoisomerism | 2010 |
Development of predictive quantitative structure-activity relationship models of epipodophyllotoxin derivatives.
Topics: Algorithms; Animals; Antineoplastic Agents, Phytogenic; Humans; Models, Molecular; Models, Statistical; Molecular Structure; Neoplasms; Podophyllotoxin; Quantitative Structure-Activity Relationship | 2010 |
Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors.
Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type II; HCT116 Cells; Hep G2 Cells; Humans; Neoplasms; Podophyllotoxin; Podophyllum; Thiourea; Topoisomerase II Inhibitors | 2011 |
Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).
Topics: Allelic Imbalance; Cell Line, Tumor; Chromosome Aberrations; Cluster Analysis; Comparative Genomic Hybridization; DNA Copy Number Variations; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genotype; Humans; In Situ Hybridization, Fluorescence; Metaphase; Neoplasms; Podophyllotoxin; Proto-Oncogene Proteins c-myc; Reproducibility of Results; RNA, Small Interfering; Spectral Karyotyping | 2011 |
Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Etoposide; Humans; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors | 2011 |
Synthesis and cytotoxicity evaluation of novel podophyllotoxin derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; HCT116 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Neoplasms; Podophyllotoxin; Spectrum Analysis; Structure-Activity Relationship | 2011 |
Facile synthesis of new 4-aza-podophyllotoxin analogs via microwave-assisted multi-component reactions and evaluation of their cytotoxic activity.
Topics: Antineoplastic Agents; Aza Compounds; Cell Line, Tumor; Cell Proliferation; Drug Design; Humans; Inhibitory Concentration 50; Microwaves; Molecular Structure; Neoplasms; Podophyllotoxin | 2011 |
Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; G2 Phase Cell Cycle Checkpoints; Humans; Inhibitor of Apoptosis Proteins; Mice; Neoplasms; Podophyllotoxin; Repressor Proteins; Survivin; Topoisomerase II Inhibitors | 2012 |
Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Comet Assay; DNA Breaks; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Etoposide; Humans; Neoplasms; Podophyllotoxin; Podophyllum | 2012 |
Prevention and handling of acute allergic and infusion reactions in oncology.
Topics: Anaphylaxis; Antibodies, Monoclonal; Asparaginase; Drug Hypersensitivity; Humans; Immunoglobulin E; Neoplasms; Platinum; Podophyllotoxin; Procarbazine; Taxoids | 2012 |
Analgesic and anti-inflammatory activity of podophyllotoxin derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carbazoles; Cell Line, Tumor; Disease Models, Animal; Drugs, Chinese Herbal; HT29 Cells; Humans; Indomethacin; Inflammation; Juniperus; Male; Mice; Naphthalenes; Neoplasms; Pain; Plant Leaves; Podophyllotoxin | 2013 |
[Clinical experiences in therapy of malignant tumors with podophyllotoxin].
Topics: Humans; Neoplasms; Podophyllin; Podophyllotoxin | 1953 |
Response of patients with advanced neoplasms to the intravenous administration of alpha-peltatin.
Topics: Administration, Intravenous; Neoplasms; Podophyllin; Podophyllotoxin | 1954 |
Enzyme changes induced in normal and malignant tissues with chemical agents. IV. Effect of alpha-peltatin on glucose utilization by sarcoma 37 and on the adenosinetriphosphatase, hexokinase, aldolase, and pyridine nucleotide levels of sarcoma 37.
Topics: Adenosine Triphosphatases; Animals; Enzymes; Fructose-Bisphosphate Aldolase; Glucose; Hexokinase; Neoplasms; Nucleotides; Podophyllin; Podophyllotoxin; Pyridines; Sarcoma 37; Sarcoma, Experimental | 1955 |
[Results in podophyllotoxin therapy of malignant tumors].
Topics: Humans; Neoplasms; Podophyllin; Podophyllotoxin; Podophyllum | 1955 |
Effects of a podophyllotoxin derivative on tissue culture systems in which human cancer invades normal tissue.
Topics: Antineoplastic Agents; Humans; Neoplasms; Podophyllin; Podophyllotoxin; Research Design; Tissue Culture Techniques | 1957 |
Disposition of biosynthetically labeled C-14 podophyllotoxin in normal and tumor-bearing animals.
Topics: Neoplasms; Personality; Podophyllin; Podophyllotoxin | 1957 |
INFERIOR vena caval occlusion.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease; Doxorubicin; Female; Humans; Neoplasms; Podophyllotoxin; Pregnancy; Pregnancy Complications; Vascular Diseases; Veins; Vena Cava, Inferior; Vincristine | 1960 |
INTRA-ARTERIAL ADMINISTRATION OF 2-ETHYLHYDRAZIDE OF PODOPHYLLIC ACID (NSC-72274) IN LOCALIZED MALIGNANT DISEASE.
Topics: Antineoplastic Agents; Biomedical Research; Drug Therapy; Hydrazines; Injections, Intra-Arterial; Neoplasms; Podophyllotoxin; Podophyllum; Toxicology | 1964 |
[THE DISTRIBUTION OF THE ANTIMITOTIC AGENT, ETHYLHYDRAZIDE OF PODOPHYLLIC ACID (SP-I 77) IN THE BODY AND IN HUMAN MALIGNANT TUMORS].
Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Autoradiography; Carcinoma; Colonic Neoplasms; Dogs; Glioma; Humans; Intestines; Kidney; Liver; Lymph Nodes; Metabolism; Neoplasms; Pharmacology; Podophyllin; Podophyllotoxin; Podophyllum; Tritium | 1964 |
Damage induced in sarcoma 37 with podophyllin, podophyllotoxin alpha-peltatin, beta-peltatin, and quercetin.
Topics: Animals; Humans; Neoplasms; Podophyllin; Podophyllotoxin; Quercetin; Sarcoma 37 | 1950 |
Effect of alpha-peltatin, beta-peltatin, podophyllotoxin on lymphomas and other transplanted tumors.
Topics: Humans; Lymphoma; Neoplasm Transplantation; Neoplasms; Podophyllin; Podophyllotoxin | 1950 |
On some chemotherapeutic experiments with podophyllotoxin.
Topics: Humans; Leukemia; Neoplasms; Podophyllin; Podophyllotoxin | 1950 |
Prophylaxis of central venous catheter-related thrombosis with minidose warfarin in patients treated with high-dose chemotherapy and peripheral-blood stem-cell transplantation: retrospective analysis of 228 cancer patients.
Topics: Administration, Oral; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Catheterization, Central Venous; Cytarabine; Female; Hemorrhage; Humans; Male; Melphalan; Neoplasms; Peripheral Blood Stem Cell Transplantation; Platelet Count; Podophyllotoxin; Retrospective Studies; Risk Factors; Transplantation, Homologous; Venous Thrombosis; Warfarin | 2006 |
The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Multidrug Resistance-Associated Proteins; Neoplasms; Phosphorylation; Podophyllotoxin; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2006 |
Incidence and clinical relevance of abnormal complete blood counts in long-term survivors of childhood cancer.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Blood Cell Count; Child; Child, Preschool; Cohort Studies; Female; Follow-Up Studies; Hematologic Diseases; Humans; Incidence; Infant; Infant, Newborn; Male; Neoplasms; Podophyllotoxin; Prognosis; Survivors | 2006 |
Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and beta-arrestin1.
Topics: Animals; Aorta; Apoptosis; Arrestins; beta-Arrestins; Blotting, Western; Cell Proliferation; Cells, Cultured; Down-Regulation; Flow Cytometry; Humans; Immunoprecipitation; Insulin-Like Growth Factor I; Mice; Neoplasms; Podophyllotoxin; Proto-Oncogene Proteins c-mdm2; Receptor, IGF Type 1; Receptor, Insulin; Swine; Ubiquitin | 2008 |
Etoposide: a new anti-cancer agent.
Topics: Animals; Drug Evaluation; Etoposide; Female; Humans; Kinetics; Lung Neoplasms; Male; Mitosis; Neoplasms; Podophyllotoxin; Testicular Neoplasms | 1981 |
The diagnostic value of circulating trophoblast-specific beta 1-glycoprotein (TSG) in cancer patients.
Topics: Female; Humans; Hydrazines; Male; Neoplasms; Podophyllin; Podophyllotoxin; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1980 |
Etoposide single-agent chemotherapy for solid tumors.
Topics: Carcinoma, Hepatocellular; Etoposide; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Sarcoma; Soft Tissue Neoplasms | 1982 |
High-dose VP-16-213 and autologous bone marrow transplantation for refractory malignancies: a phase I study.
Topics: Adolescent; Adult; Aged; Blood Cell Count; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Evaluation; Drug Resistance; Etoposide; Female; Humans; Male; Middle Aged; Neoplasms; Podophyllotoxin | 1983 |
Penetration of VP-16 (etoposide) into human intracerebral and extracerebral tumors.
Topics: Brain Neoplasms; Etoposide; Glioma; Half-Life; Humans; Kinetics; Necrosis; Neoplasms; Podophyllotoxin | 1984 |
High-dose etoposide for refractory malignancies: a phase I study.
Topics: Adult; Aged; Bone Marrow; Diarrhea; Drug Evaluation; Erythema; Etoposide; Female; Humans; Male; Middle Aged; Mouth Diseases; Neoplasm Metastasis; Neoplasms; Paresthesia; Podophyllotoxin; Reflex | 1984 |
Pharmacokinetics of etoposide (VP16) in children and adolescents with refractory solid tumors.
Topics: Adolescent; Adult; Child; Child, Preschool; Cisplatin; Etoposide; Female; Humans; Kinetics; Leukemia; Male; Metabolic Clearance Rate; Neoplasms; Podophyllotoxin | 1984 |
Pharmacokinetics of high-dose etoposide (VP-16-213) administered to cancer patients.
Topics: Etoposide; Half-Life; Humans; Kinetics; Neoplasms; Podophyllotoxin | 1984 |
New anticancer drug class.
Topics: Child; Etoposide; Humans; Legislation, Drug; Neoplasms; Podophyllotoxin; Teniposide; United States | 1983 |
Pilot studies of various combinations of dibromodulcitol, VP-16, and AMSA.
Topics: Aged; Aminoacridines; Amsacrine; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Middle Aged; Mitolactol; Neoplasms; Pilot Projects; Podophyllotoxin | 1982 |
[Prospects of new chemotherapies].
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Neoplasms; Podophyllotoxin; Vinblastine; Vindesine | 1982 |
Etoposide (VP16-213) and teniposide (VM26) comparative in vitro activities in human tumors.
Topics: Antineoplastic Agents; Cells, Cultured; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Teniposide | 1982 |
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
A phase I trial of continuous infusion VP16-213 (etoposide).
Topics: Adult; Aged; Drug Evaluation; Etoposide; Female; Heart Diseases; Hematologic Diseases; Humans; Infusions, Parenteral; Male; Middle Aged; Neoplasms; Podophyllotoxin | 1982 |
The International Symposium on the Podophyllotoxins in Cancer Therapy, Southhampton, England, July 8-9, 1981.
Topics: Humans; Neoplasms; Podophyllotoxin | 1982 |
Proceedings of the German Cancer Society (Clinical Oncology Section) and Bristol-Myers GmbH Symposium on Etoposide (VP-16). Current status and new developments. Frankfurt, 21-22 May 1981.
Topics: Etoposide; Humans; Neoplasms; Podophyllotoxin | 1982 |
[Etoposide: VP-16].
Topics: Etoposide; Humans; Lung Neoplasms; Lymphoma; Neoplasms; Podophyllotoxin | 1982 |
[General principles and new trends of cytostatic tumor therapy].
Topics: Antineoplastic Agents; Cisplatin; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Neoplasms; Nitrosourea Compounds; Podophyllotoxin; Radiation-Sensitizing Agents; Razoxane | 1980 |
Preliminary study of the combination, dianhydrogalactitol, cis-diaminedichloroplatinum (II), and VP-16-213 in patients with advanced cancer.
Topics: Brain Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Dianhydrogalactitol; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pilot Projects; Podophyllotoxin; Sugar Alcohols | 1981 |
VP-16-213. A phase II trial using a weekly schedule.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Etoposide; Humans; Neoplasms; Podophyllotoxin | 1981 |
Phase II study of VM-26 in adult malignancies.
Topics: Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide; Thrombocytopenia | 1980 |
Expression of adhesion molecules on CD34+ cells: CD34+ L-selectin+ cells predict a rapid platelet recovery after peripheral blood stem cell transplantation.
Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Marrow; Bone Marrow Cells; Carboplatin; Carmustine; Cell Adhesion Molecules; Cell Movement; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Epirubicin; Etoposide; Female; Fluorouracil; Gene Expression; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Ifosfamide; L-Selectin; Leukocyte Count; Male; Melphalan; Middle Aged; Neoplasms; Neutrophils; Platelet Count; Podophyllotoxin; Receptors, Very Late Antigen; Thiotepa | 1995 |
Cancer morbidity in rheumatoid arthritis patients treated with Proresid or parenteral gold.
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Cohort Studies; Female; Gold Sodium Thiomalate; Humans; Infusions, Parenteral; Male; Morbidity; Neoplasms; Podophyllin; Podophyllotoxin; Risk Factors; Sweden | 1995 |
High-performance liquid chromatographic assay for the determination of the novel podophyllotoxin derivative dimethylaminoetoposide (NK611) in human plasma.
Topics: Antineoplastic Agents; Biological Availability; Chromatography, High Pressure Liquid; Humans; Metabolic Clearance Rate; Neoplasms; Podophyllotoxin; Quality Control; Sensitivity and Specificity | 1994 |
Proresid therapy in rheumatoid arthritis. A comparison with injectable gold using life-table analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cohort Studies; Female; Gold; Humans; Incidence; Injections; Life Tables; Male; Middle Aged; Neoplasms; Patient Compliance; Patient Dropouts; Podophyllin; Podophyllotoxin; Prognosis; Risk Factors; Treatment Outcome | 1993 |
Back-up bone marrow is frequently ineffective in patients with poor peripheral-blood stem-cell mobilization.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Transfusion; Bone Marrow; Carmustine; Combined Modality Therapy; Cryopreservation; Cyclophosphamide; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Neoplasms; Podophyllotoxin; Treatment Failure | 1998 |
Association of CYP3A4 genotype with treatment-related leukemia.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Chromosome Mapping; Chromosomes, Human, Pair 11; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Ethnicity; Female; Histone-Lysine N-Methyltransferase; Humans; Karyotyping; Leukemia; Male; Mixed Function Oxygenases; Myeloid-Lymphoid Leukemia Protein; Neoplasms; Neoplasms, Second Primary; Phenotype; Podophyllotoxin; Proto-Oncogenes; Racial Groups; Transcription Factors; United States | 1998 |
A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Death; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Etoposide; Humans; Neoplasms; Podophyllotoxin; Tumor Cells, Cultured | 1999 |
A clinical trial of the oral form of 4'-demethyl-epipodophyllotoxin-beta-D ethylidene glucoside (NSC 141540) VP 16-213.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Glucosides; Humans; Leukemia, Myeloid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mesothelioma; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Urinary Bladder Neoplasms | 1975 |
[Therapeutic experiences using the new podophyllotoxin derivative VP 16-213 in malignant human tumors].
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Prostatic Neoplasms; Remission, Spontaneous | 1975 |
Prostaglandins and cancer.
Topics: Amino Acid Sequence; Animals; Anthralin; Binding Sites; Cathartics; Cell Transformation, Neoplastic; Humans; Models, Molecular; Neoplasms; Neoplasms, Experimental; Phorbol Esters; Podophyllotoxin; Polyamines; Prostaglandins; Receptors, Prostaglandin | 1979 |
Lack of severe hypotension with VP-16-213 administered directly lv.
Topics: Adult; Aged; Blood Pressure; Etoposide; Humans; Infusions, Parenteral; Middle Aged; Neoplasms; Podophyllotoxin | 1977 |
[Catamnestic-statistical results of Proresid treatment of malignant tumors].
Topics: Drug Evaluation; Humans; Neoplasms; Podophyllotoxin | 1978 |
EPEG, a new antineoplastic epipodophyllotoxin.
Topics: Adult; Antineoplastic Agents; Drug Evaluation; Humans; Infusions, Parenteral; Middle Aged; Neoplasms; Podophyllotoxin; Time Factors | 1975 |
PTG, a new antineoplastic epipodyphyllotoxin.
Topics: Adult; Antineoplastic Agents; Drug Evaluation; Humans; Infusions, Parenteral; Middle Aged; Neoplasms; Podophyllotoxin | 1975 |
Comparison of the human pharmacokinetics of VM-26 and VP-16, two antineoplastic epipodophyllotixin glucopyranoside derivatives.
Topics: Body Water; Etoposide; Humans; Metabolic Clearance Rate; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1975 |
Combination chemotherapy based on a model of cell recruitment by partial synchronization.
Topics: Drug Therapy, Combination; Humans; Mitosis; Mitotic Index; Models, Biological; Neoplasm Metastasis; Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Time Factors; Vincristine | 1975 |
[Phase I trial and pharmacokinetics of VM 26 combined with cisplatin administered by the intraperitoneal route without mixing time].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Humans; Injections, Intraperitoneal; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide | 1989 |
Treatment strategies in relation to drug action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Inhibitors of topoisomerase II: structure-activity relationships and mechanism of action of podophyllin congeners.
Topics: Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Resistance; Humans; Neoplasms; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1988 |
Etoposide: a pharmacokinetic profile including an assessment of bioavailability.
Topics: Administration, Oral; Biological Availability; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Hodgkin Disease; Humans; Injections, Intravenous; Kinetics; Lung Neoplasms; Lymphoma; Male; Neoplasms; Podophyllotoxin | 1986 |
Side effects of Proresid in the treatment of chronic arthritis.
Topics: Aged; Amyloidosis; Arthritis; Diarrhea; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Neoplasms; Podophyllin; Podophyllotoxin | 1988 |
Influence of polysorbate 80 (Tween 80) and etoposide (VP-16-213) on the pharmacokinetics and urinary excretion of adriamycin and its metabolites in cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Interactions; Etoposide; Female; Humans; Kinetics; Male; Middle Aged; Neoplasms; Pharmaceutical Vehicles; Podophyllotoxin; Polysorbates | 1986 |
High-dose teniposide for refractory malignancies: a phase I study.
Topics: Adult; Aged; Alopecia; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Middle Aged; Nausea; Neoplasms; Podophyllotoxin; Skin Diseases; Teniposide | 1986 |
[A phase I study of VP-16-213 (VP, etoposide) by single and 5-day intravenous administration].
Topics: Adult; Aged; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Kinetics; Leukopenia; Male; Middle Aged; Neoplasms; Podophyllotoxin; Thrombocytopenia | 1986 |
Pharmacokinetics of high-dose melphalan in children and adults.
Topics: Adolescent; Adult; Carmustine; Child; Child, Preschool; Diuresis; Dose-Response Relationship, Drug; Furosemide; Half-Life; Humans; Kinetics; Melphalan; Middle Aged; Neoplasms; Podophyllotoxin; Procarbazine | 1986 |
Proceedings: Zearalenone in the diet, podophyllotoxin in the wood shavings bedding, are likely to affect the incidence of "spontaneous" tumours among laboratory animals.
Topics: Animal Feed; Animals; Animals, Laboratory; Carcinogens; Diet; Estrogens; Fusarium; Lactones; Mycotoxins; Neoplasms; Podophyllotoxin; Resorcinols; Wood | 1974 |
Letter: Role of podophyllotoxin in the bedding and dietary zearalenone on incidence of spontaneous tumors in laboratory animals.
Topics: Animals; Animals, Laboratory; Carcinogens; Diet; Environmental Exposure; Estrogens; Housing, Animal; Lactones; Liver Neoplasms; Mammary Glands, Animal; Mice; Mice, Inbred C3H; Mycotoxins; Neoplasms; Podophyllotoxin; Resorcinols | 1974 |
Failure of resin of podophyllum in the treatment of verruca vulgaris.
Topics: Adenoma; Humans; Neoplasms; Podophyllin; Podophyllum; Warts | 1947 |
[A case of melanocarcinoma of the temporal region improved by podophyllin].
Topics: Face; Facial Neoplasms; Head; Melanoma; Neoplasms; Podophyllin; Podophyllum; Temporal Lobe | 1960 |
Some biochemical responses of normal and malignant tissues to tumor-necrotizing agents.
Topics: Antineoplastic Agents; Humans; Neoplasms; Podophyllin; Podophyllum | 1959 |
[Possibilities and limitations of additional control of malignant tumors by cytostatics, especially by podophyllin derivatives].
Topics: Cytostatic Agents; Humans; Neoplasms; Podophyllin; Podophyllum; Radiotherapy | 1962 |
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine | 1963 |
[CHANGES IN LIP MUCOSA AND SKIN OF RATS RECEIVING PODOPHYLLIN].
Topics: Lip; Lip Neoplasms; Mucous Membrane; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Podophyllin; Podophyllum; Rats; Research; Toxicology | 1963 |
[EARLY DIAGNOSIS AND MEDICAL THERAPY OF MALIGNANT TUMORS].
Topics: Antineoplastic Agents; Busulfan; Colchicine; Early Diagnosis; Hodgkin Disease; Mechlorethamine; Mercaptopurine; Neoplasms; Phenylalanine; Podophyllum; Triethylenemelamine; Vinblastine | 1963 |
COMPARATIVE STUDIES OF THE ACTION OF CHEMOTHERAPEUTICS ON INDUCED AND TRANSPLANTED TUMORS.
Topics: Antineoplastic Agents; Colchicine; Cyclophosphamide; Mannomustine; Melphalan; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Podophyllum; Research; Skin Neoplasms | 1964 |
CATALASE ACTIVITY IN THE EPIDERMIS OF PATIENTS WITH ADVANCED CANCER.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbamates; Catalase; Clinical Enzyme Tests; Cobalt Isotopes; Cyclophosphamide; Drug Therapy; Epidermis; Fluorouracil; Humans; Neoplasms; Podophyllum; Skin | 1964 |
[THERAPY OF TERMINAL CANCER STAGES WITH SP-G AND SP-I. 1ST AND PRELIMINARY COMMUNICATION].
Topics: Antineoplastic Agents; Biomedical Research; Communication; Humans; Neoplasms; Podophyllum | 1964 |
SKIN CHANGES CAUSED BY CANCER CHEMOTHERAPY.
Topics: Alopecia; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dermatology; Erythema; Ethoglucid; Fluorouracil; Neoplasms; Pathology; Podophyllum; Skin; Sweat Glands; Toxicology; Ulcer | 1964 |
FATAL POISONING WITH PODOPHYLLUM RESIN.
Topics: Antineoplastic Agents; Female; Humans; Neoplasms; Ovarian Neoplasms; Plant Poisoning; Podophyllin; Podophyllum; Resins, Synthetic; Toxicology | 1964 |
[ATTEMPTED TREATMENT OF CANCER IN AN ADVANCED STAGE BY PODOPHYLLIN DERIVATIVES].
Topics: Antineoplastic Agents; Drug Therapy; Geriatrics; Neoplasms; Podophyllin; Podophyllum; Toxicology | 1964 |
[ON GENERAL AND LOCAL ANTIMITOTIC THERAPY OF GENITAL CARCINOMA WITH THE PODOPHYLLINIC DERIVATIVES SP-I AND SP-G].
Topics: Antimitotic Agents; Antineoplastic Agents; Carcinoma; Female; Genital Neoplasms, Female; Geriatrics; Humans; Neoplasms; Podophyllin; Podophyllum; Toxicology | 1964 |
[TRIAL OF A CHEMOTHERAPEUTIC PREVENTION OF RECURRENCE AND METASTASIS OF OPERATIVE AND SUBSEQUENTLY IRRADIATED BREAST CARCINOMA].
Topics: Breast Neoplasms; Carcinoma; Drug Therapy; Humans; Mastectomy; Neoplasm Recurrence, Local; Neoplasms; Podophyllum | 1964 |
GIANT CONDYLOMA AND VERRUCOUS CARCINOMA OF THE GENITAL AREA.
Topics: Buschke-Lowenstein Tumor; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Genitalia, Male; Humans; Lymphatic Metastasis; Male; Neoplasms; Papilloma; Pathology; Penile Neoplasms; Podophyllin; Podophyllum; Scrotum; Skin Neoplasms; Surgical Procedures, Operative | 1965 |
[RESULTS OF OUR EXPERIENCE WITH SP-I AND SP-G IN THE TREATMENT OF MALIGNANT NEOPLASMS].
Topics: Antineoplastic Agents; Neoplasms; Podophyllin; Podophyllum; Toxicology | 1963 |
[THE VALUE OF THE ADDITION OF A PODOPHYLLUM TOXIN COMPOUND TO THE SURGICAL AND RADIOLOGICAL TREATMENT OF MAMMARY CARCINOMAS].
Topics: Antineoplastic Agents; Breast Neoplasms; Humans; Neoplasms; Podophyllin; Podophyllum; Toxicology | 1965 |
[LATEST RESEARCH ON ALTERATIONS OF THE MUCOSA AND SKIN OF THE LIP OF THE RAT CAUSED BY PODOPHYLLIN].
Topics: Carcinogens; Lip; Mucous Membrane; Necrosis; Neoplasms; Neoplasms, Experimental; Podophyllin; Podophyllum; Rats; Research; Skin Ulcer; Toxicology | 1965 |
[A SUPPLEMENT TO CANCER OPERATIONS BY PODOPHYLLIN DERIVATIVES].
Topics: Antineoplastic Agents; Dietary Supplements; Humans; Neoplasms; Podophyllin; Podophyllum; Surgical Procedures, Operative | 1964 |
Preliminary report of lysis of mouse sarcoma 37 by a component isolated from resin of podophyllum.
Topics: Animals; Mice; Neoplasms; Podophyllin; Podophyllum; Resins, Plant; Sarcoma; Sarcoma 37 | 1951 |
Resin of Podophyllum in treatment of cancerous and precancerous conditions of skin.
Topics: Humans; Keratosis; Keratosis, Actinic; Neoplasms; Podophyllum; Precancerous Conditions; Skin | 1950 |
Treatment of juvenile papilloma of the larynx with resin of podophyllum; a preliminary report.
Topics: Adolescent; Humans; Larynx; Neoplasms; Papilloma; Podophyllin; Podophyllum; Resins, Plant | 1950 |
Human anticancer effect of podophyllum derivatives (SPG and SPI): a preliminary report.
Topics: Adult; Deglutition Disorders; Esophageal Neoplasms; Gingiva; Humans; Injections, Intra-Arterial; Male; Mandibular Neoplasms; Mouth; Mouth Neoplasms; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1967 |
[Action mechanism of cytostatic podophyllum derivates].
Topics: Animals; Female; Humans; L-Lactate Dehydrogenase; Malate Dehydrogenase; Mice; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1967 |
SPI and SPG in the treatment of advanced malignant lesions.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Hormones; Humans; Leukopenia; Neoplasms; Paralysis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1967 |
[Clinical trial of chemotherapeutic combinations based on the notion of attempted cellular synchronization. Preliminary administration of an antimitotic followed by the use of cycle-dependent or phase dependent product(s)].
Topics: Amino Sugars; Anthraquinones; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Daunorubicin; DNA; Drug Combinations; Drug Tolerance; Female; Hodgkin Disease; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mitosis; Neoplasm Metastasis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Prognosis; Time Factors | 1972 |
Clinical investigation of a new podophyllum derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidene- -D-glucopyranoside) (NSC-122819), in patients with malignant lymphomas and solid tumors.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Female; Glycosides; Haplorhini; Hodgkin Disease; Humans; Immunosuppression Therapy; Lactones; Lymphoma; Male; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Rats; Thiophenes | 1972 |
[New possibilities in testing resistance of human carcinoma tissue to cytostatic agents in vivo].
Topics: Animals; Cyclophosphamide; Humans; Methotrexate; Neoplasm Transplantation; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Rats; Thiotepa; Triaziquone | 1967 |
[The chemotherapy of cancer].
Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Sarcoma, Ewing; Thiotepa; Vincristine | 1967 |
[Experimental bases and clinical aspects of the use of 2 antimitotic derivatives of podophyllum].
Topics: Animals; Antineoplastic Agents; Cell Division; Humans; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Rats | 1965 |
[Considerations on the use of Proresid (SPI-SPG Sandoz) as an adjuvant in the treatment of tumors (preliminart communication)].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Child; Female; Humans; Male; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1968 |
[Therapeutic effects of podophyllin derivatives on malignant neoplasms].
Topics: Aged; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1968 |
[Internal treatment of carcinoma with the cytostatic Proresid].
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Infusions, Parenteral; Kidney Neoplasms; Lymphoma, Large B-Cell, Diffuse; Middle Aged; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Peritonitis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Pleural Neoplasms; Pleurisy; Podophyllum; Stomach Neoplasms; Uterine Neoplasms | 1966 |
[Studies on the understanding of problems of radiologic cytostatic combination treatment. 6. Further syncytostatic studies with 5-fluorouracil, natulan and proresid].
Topics: Amides; Animals; Antineoplastic Agents; Cyclophosphamide; Ear, External; Female; Fluorouracil; Granulation Tissue; Hydrazines; Mice; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Radiation Effects; Radiation Injuries, Experimental; Radiotherapy Dosage; Statistics as Topic; Tail; Wound Healing | 1969 |
[Clinical studies of the method of application of antineoplastic agents].
Topics: Antineoplastic Agents; Blood Cell Count; Bone Marrow Examination; Cyclophosphamide; Fluorouracil; Humans; Hydrazines; Injections; Mitomycins; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1970 |
[Clinical experiences with SP-I].
Topics: Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1967 |
Effect of podophyllum products S.P.I.&S.P.G. on malignant diseases.
Topics: Antineoplastic Agents; Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1968 |
[Plasma iron turnover before and following cytostatic therapy and its signifiance as indicator of tumor activity].
Topics: Antineoplastic Agents; Breast Neoplasms; Female; Follow-Up Studies; Humans; Iron; Iron Isotopes; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Prostatic Neoplasms; Rectal Neoplasms; Thyroid Neoplasms; Time Factors; Urinary Bladder Neoplasms | 1968 |
[Clinical use of podophyllin derivatives SP-I and SP-G in the treatment of cancer].
Topics: Adult; Female; Humans; Male; Middle Aged; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1968 |
[Cytostatic therapy of metastatic and advanced malignant tumors of the ENT region with podophyllin derivatives (SPI-SPG)].
Topics: Humans; Neoplasms; Otorhinolaryngologic Diseases; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1965 |
[On the treatment of malignant tumors with podophyllotoxin derivatives].
Topics: Antineoplastic Agents; Cell Division; Culture Techniques; Hematopoiesis; Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1965 |
A five-year follow-up of treating cancer with cobalt radiation and cytotoxic drugs.
Topics: Cobalt Isotopes; Follow-Up Studies; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1966 |
[Submicroscopic changes in human cancer cells under the effect of SP-I and SP-G "Sandoz"].
Topics: Aged; Antineoplastic Agents; Female; Humans; Male; Microscopy, Electron; Middle Aged; Neoplasms; Otorhinolaryngologic Diseases; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1966 |
[Treatment of malignant tumors with SP-I/SP-G Sandoz (Proresid)].
Topics: Adult; Antineoplastic Agents; Female; Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1966 |