podophyllotoxin has been researched along with Malignant Melanoma in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D | 1 |
| Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS | 1 |
| Castro, MA; Cuevas, C; de la Iglesia-Vicente, J; del Corral, JM; García, PA; Mollinedo, F; Rojo, MV; San Feliciano, A | 1 |
| All-Ericsson, C; Andersson, S; Axelson, M; Economou, MA; Girnita, A; Girnita, L; Larsson, O; Menu, E; Seregard, S; Vasilcanu, D | 2 |
| All-Ericsson, C; Aström, K; Axelson, M; Economou, MA; Girnita, A; Girnita, L; Larsson, O; Seregard, S | 2 |
| Economou, MA | 1 |
| Hei, TK; Ivanov, VN; Karasic, TB | 1 |
| Axelson, M; Girnita, A; Girnita, L; Larsson, O; Vasilcanu, D; Vasilcanu, R | 1 |
| Axelson, M; Girnita, A; Girnita, L; Sehat, B; Vasilcanu, D; Vasilcanu, R; Yin, S | 1 |
| Courdi, A; Ettore, F; Fischel, JL; Gioanni, J; Lalanne, CM; Lambert, JC; Schneider, M | 1 |
| Bellet, RE; Berd, D; Catalno, RB; Koons, LS; Mastrangelo, MJ | 1 |
| Al-Sarraf, M; Cecil, JW; Coltman, CA; Groppe, CW; Quagliana, JM; Thigpen, T | 1 |
| Ahmann, DL; Bisel, HF; Edmonson, JH; Frytak, S; Hahn, RG; O'Connell, MJ | 1 |
| Lönn, S; Lönn, U; Nylen, U; Winblad, G | 1 |
| FISCHER, R | 1 |
| SOELTZ-SZOETS, J | 1 |
| Ackerman, AB; Connors, RC | 1 |
| Bilder, J; Hornová, J | 1 |
| Hansen, HH; Muggia, FM; Selawry, OS | 1 |
3 trial(s) available for podophyllotoxin and Malignant Melanoma
| Article | Year |
|---|---|
Phase II trial of VM-26 in patients with metastatic malignant melanoma.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide | 1978 |
Phase II study of VP-16-213 versus dianhydrogalactitol in patients with metastatic malignant melanoma.
Topics: Drug Evaluation; Drug Therapy, Combination; Ethers, Cyclic; Etoposide; Female; Galactitol; Humans; Male; Melanoma; Podophyllotoxin; Sugar Alcohols | 1976 |
Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819).
Topics: Aged; Antineoplastic Agents; Astrocytoma; Clinical Trials as Topic; Esophageal Neoplasms; Evaluation Studies as Topic; Fibroblasts; Glycosides; Humans; Hypotension; Lactones; Leiomyosarcoma; Leukopenia; Liver Neoplasms; Lung Neoplasms; Melanoma; Middle Aged; Mitosis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Structure-Activity Relationship; Thiophenes; Thrombocytopenia | 1971 |
19 other study(ies) available for podophyllotoxin and Malignant Melanoma
| Article | Year |
|---|---|
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1991 |
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Synthesis and biological evaluation of new podophyllic aldehyde derivatives with cytotoxic and apoptosis-inducing activities.
Topics: Aldehydes; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma; Molecular Structure; Podophyllotoxin; Tumor Cells, Cultured | 2010 |
Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Proliferation; Cell Survival; Humans; Melanoma; Mice; Mice, SCID; Neoplasm Transplantation; Podophyllotoxin; Receptor, IGF Type 1; Specific Pathogen-Free Organisms; Transplantation, Heterologous; Tumor Cells, Cultured; Uveal Neoplasms; Vascular Endothelial Growth Factor A | 2008 |
Introduction: Uveal melanoma.
Topics: Administration, Oral; Animals; Humans; Melanoma; Neoplasm Metastasis; Podophyllotoxin; Prognosis; Proto-Oncogene Proteins c-met; Receptor, IGF Type 1; Uveal Neoplasms; Vascular Endothelial Growth Factor A | 2008 |
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Extracellular Matrix Proteins; Humans; Matrix Metalloproteinase Inhibitors; Melanoma; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Phosphorylation; Podophyllotoxin; Receptor, IGF Type 1; Transplantation, Heterologous; Uveal Neoplasms | 2008 |
Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Mice; Mice, SCID; Neoplasm Transplantation; Podophyllotoxin; Receptor, IGF Type 1; Transplantation, Heterologous; Uveal Neoplasms; Vascular Endothelial Growth Factor A | 2008 |
Uveal melanoma and macular degeneration: molecular biology and potential therapeutic applications.
Topics: Animals; Biomarkers; Humans; Macular Degeneration; Melanoma; Mice; Molecular Biology; Podophyllotoxin; Prognosis; Receptor, IGF Type 1; Signal Transduction; Uveal Neoplasms; Vascular Endothelial Growth Factor A | 2008 |
Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: a new potential therapy for the treatment of melanoma.
Topics: Apoptosis; Cell Survival; Humans; Melanoma; Podophyllotoxin; Receptor, IGF Type 1; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2010 |
The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Cell Survival; Fibroblasts; Humans; Insulin Receptor Substrate Proteins; Kinetics; Melanoma; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Podophyllotoxin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Recombinant Proteins; Transfection | 2004 |
The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
Topics: Animals; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, SCID; Neoplasm Invasiveness; Phosphorylation; Podophyllotoxin; Receptor, IGF Type 1; Uveal Neoplasms; Xenograft Model Antitumor Assays | 2006 |
Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
Topics: Cell Survival; Enzyme Activation; Enzyme Induction; Glioblastoma; Humans; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; RNA, Small Interfering; Signal Transduction; Transfection; Tumor Cells, Cultured; Ubiquitination | 2008 |
Establishment, characterization, and response to cytotoxic and radiation treatment of three human melanoma cell lines.
Topics: Aged; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Chromosomes; Clone Cells; Cobalt Radioisotopes; Female; Humans; Karyotyping; Male; Melanocytes; Melanoma; Middle Aged; Organoids; Podophyllotoxin | 1983 |
Evaluation of VP-16-213 in malignant lymphoma and melanoma.
Topics: Adult; Drug Evaluation; Etoposide; Female; Hodgkin Disease; Humans; Lymphoma; Male; Melanoma; Podophyllotoxin | 1978 |
Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide).
Topics: DNA Replication; DNA, Neoplasm; Etoposide; Humans; Kinetics; Melanoma; Podophyllotoxin; Teniposide; Thymidine; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1989 |
[A case of melanocarcinoma of the temporal region improved by podophyllin].
Topics: Face; Facial Neoplasms; Head; Melanoma; Neoplasms; Podophyllin; Podophyllum; Temporal Lobe | 1960 |
[CELL CULTURE STUDIES ON MELANOMA THERAPY].
Topics: Antineoplastic Agents; Cyclophosphamide; Humans; Melanoma; Podophyllum; Quinones; Tissue Culture Techniques | 1963 |
Histologic pseudomalignancies of the skin.
Topics: Carcinoma; Condylomata Acuminata; Cysts; Dermatitis, Contact; Diagnosis, Differential; Fibroma; Humans; Hyperplasia; Keratoacanthoma; Keratosis; Lymphoma; Melanoma; Nevus; Pityriasis; Plants, Medicinal; Plants, Toxic; Podophyllum; Skin; Skin Diseases; Skin Neoplasms | 1976 |
[Proresid-methotrexate combination in chemotherapy of orofacial carcinoma].
Topics: Agranulocytosis; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Humans; Infections; Injections, Intra-Arterial; Leukopenia; Lip Neoplasms; Melanoma; Methotrexate; Mouth Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Tongue Neoplasms | 1970 |