podophyllotoxin has been researched along with Lung Neoplasms in 211 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 164 (77.73) | 18.7374 |
| 1990's | 18 (8.53) | 18.2507 |
| 2000's | 4 (1.90) | 29.6817 |
| 2010's | 19 (9.00) | 24.3611 |
| 2020's | 6 (2.84) | 2.80 |
| Authors | Studies |
|---|---|
| Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D | 1 |
| Chu, DT; Clement, JJ; Klein, LL; McDonald, EJ; Plattner, JJ; Yeung, CM | 1 |
| Feringa, BL; Jansen, JF; Kellogg, RM; Konings, AW; Middel, O; Pras, N; van Oeveren, A; van Uden, W; Woerdenbag, HJ | 1 |
| Hamel, E; Kuo, SC; Lednicer, D; Lee, KH; Li, L; Lin, CM; Wang, HK; Wu, TS | 1 |
| Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS | 1 |
| Castro, MA; Cuevas, C; de la Iglesia-Vicente, J; del Corral, JM; García, PA; Mollinedo, F; Rojo, MV; San Feliciano, A | 1 |
| Guo, S; Huang, Z; Ju, B; Wang, R; Wang, W; Xuan, Y; Zhang, S; Zhao, Y; Zhen, Y; Zhou, Y | 1 |
| Ju, B; Ma, P; Wang, R; Wang, W; Xuan, Y; Zhang, S; Zhao, Y; Zhen, Y | 1 |
| Ai, D; Chen, Q; Gao, J; Lin, H; Liu, Q; Ruan, L; Tao, Y; Wang, L; Wang, X | 1 |
| Chae, JI; Cho, SS; Kim, E; Kwak, AW; Lee, MH; Liu, K; Oh, HN; Shim, JH; Yoon, G | 1 |
| Fei, J; Gong, P; Xiao, C; Yang, M; Zhou, X | 1 |
| Chae, JI; Cho, SS; Kim, E; Kim, HS; Kwak, AW; Lee, MH; Oh, HN; Seo, JH; Shim, JH; Yoon, G | 1 |
| Klassen, T; Li, SD; Roy, A; Szeitz, A; Yang, Y; Zhao, Y | 1 |
| Chen, Y; Tao, N; Wang, J; Xie, Q; Xu, Y; Yang, C; Zeng, X; Zhang, L | 1 |
| Chen, JY; Chiou, YC; Li, WS; Shieh, JM; Tang, YA; Wang, YC | 1 |
| Chen, M; Duan, H; Gao, Q; Jiang, Z; Song, Y; Sun, L; Wang, Y; Wu, M; Zhang, L; Zhang, S; Zhu, X | 1 |
| Chen, SW; Hui, L; Liu, JF; Qin, WW; Sang, CY; Xu, XH | 1 |
| Lubet, RA; Pan, J; Wang, Y; You, M; Zhang, Q | 1 |
| Abrahmsén, L; Akopyan, K; Aleem, E; Axelson, M; Larsson, O; Lindqvist, A; Parrow, V; Strömberg, T; Waraky, A | 1 |
| Bergqvist, M; Bergström, S; Brandén, E; Ekman, S; Harmenberg, J; Holgersson, G; Jerling, M; Klockare, M; Koyi, H; Larsson, O; Lundström, KL; Ringbom, M | 1 |
| Abrahmsen, L; Alvfors, C; Axelson, M; Bergqvist, M; Bergström, S; Ekman, S; Eksborg, S; Frödin, JE; Harmenberg, J; Hedlund, Å; Jerling, M; Larsson, O; Ståhl, B; Wassberg, C | 1 |
| Cho, JH; Choi, JY; Hong, WG; Hwang, SG; Jung, CH; Kim, EM; Kim, J; Park, JK; Um, HD | 1 |
| Bagul, C; Kamal, A; Mallareddy, A; Nayak, VL; Vishnuvardhan, MV | 1 |
| Chen, S; Hui, L; Jia, Q; Ma, M; Sang, C; Wang, D; Wang, M; Wang, X | 1 |
| Cho, JH; Hong, WG; Hwang, SG; Jung, YJ; Lee, E; Lee, J; Park, JK; Um, HD | 1 |
| Cho, JH; Hong, WG; Hwang, SG; Kim, JI; Lee, E; Lee, J; Park, JK; Um, HD | 1 |
| Fu, Y; Guo, L; He, Q; Li, C; Li, J; Wang, X; Zhang, Z; Zhou, M | 1 |
| Andor, G; Bergqvist, M; Bondarenko, I; Grechanaya, E; Harmenberg, J; Holgersson, G; Jerling, M; Klockare, M; Maximovich, A; Thureson, M | 1 |
| Annereau, JP; Bailly, C; Barret, JM; Brel, V; Delcros, JG; Guilbaud, N; Guminski, Y; Imbert, T; Kruczynski, A; Lansiaux, A; Vispé, S | 1 |
| Liang, CY; Liu, X; Tian, XD; Zhang, JM; Zhang, T; Zhou, NK | 1 |
| Chen, MC; Lee, KH; Li, TK; Pan, SL; Shi, Q; Teng, CM; Xiao, Z | 1 |
| Bunn, PA; Simon, GR | 1 |
| Haaxma-Reiche, H; Meinesz, AF; Mulder, NH; Postmus, PE; Sleijfer, DT; Vencken, LM | 1 |
| Antman, K; Canellos, G; Karp, G; Pomfret, E; Skarin, A | 1 |
| Kinameri, K; Kurita, Y; Yokoyama, A | 1 |
| Bender, HW; Foster, JM; Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Prager, RL; Wolff, SN | 1 |
| Caldwell, RD; Case, LD; Harding, RW; Hopkins, JO; Jackson, DV; Muss, HB; Richards, F; Slatkoff, ML; White, DR; Zekan, PJ | 1 |
| De Vries, EG; Meinesz, AF; Mulder, NH; Orie, JL; Postmus, PE; Sleijfer, DT; Van der Geest, S; Vriesendorp, R | 1 |
| Bork, E; Dombernowsky, P; Hansen, HH; Osterlind, K; Pedersen, AG | 1 |
| Arnold, AM; Whitehouse, JM | 1 |
| Bagwell, S; Broder, LE; Charyulu, KN; Ng, A; Selawry, OS | 1 |
| Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, RA; Sonntag, RW | 1 |
| Kessinger, A; Lemon, HM; Tempero, M | 1 |
| Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R; Ryssel, HJ; Sonntag, RW | 1 |
| Kennedy, BJ; Raghavan, D; Vogelzang, NJ | 1 |
| Bunn, PA; Cohen, MH; Hawley, RJ; Ihde, DC; Matthews, MJ; Minna, JD; Smith, MT; Thant, M; West, W | 1 |
| Calciati, A; Conte, PF; Giaccone, G; Musella, R | 1 |
| Cortés Funes, H; Dominguez, P; Lanzos, E; Mendez, M; Mendiola, C; Torrubia, AP | 1 |
| Aisner, J; VanEcho, DA; Wesley, M; Whitacre, M; Wiernik, PH | 1 |
| Gomez, RG; Madrigal, PA; Manga, GP; Palomero, I | 1 |
| Bowden, GT; Giever, RJ; Heusinkveld, RS; Manning, MR | 1 |
| Bitran, JD; DeMeester, TR; Golomb, HM; Hoffman, PC; Newman, SB; Raghavan, V | 1 |
| Bremer, K; Krischke, W; Niederle, N; Schmidt, CG; Seeber, S | 1 |
| Ammon, J; Essers, U; Knechten, H; Seelis, R | 1 |
| Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R | 1 |
| Natale, RB; Wittes, RE | 1 |
| Havemann, K | 1 |
| Agusti, A; Estape, J; Milla, A; Rozman, C; Sanchez-Lloret, J; Santabarbara, P | 1 |
| Cooper, MR; Jackson, DV; Muss, HB; Pope, EK; Richards, F; Spurr, CL; Stuart, JJ; Wells, HB; White, DR | 1 |
| Asbury, RF; Bennett, JM; Rubins, J | 1 |
| Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Wolff, SN | 1 |
| Hansen, HH; Pedersen, AG | 1 |
| Deboer, G; Dill, J; Evans, WK; Feld, R; Osoba, D; Shepherd, FA | 1 |
| Canellos, GP; Garnick, MB; Lederman, GS; Richie, JP | 1 |
| Davis, SL; Goodman, GE; Manning, MM; McMahon, LJ; Miller, TP | 1 |
| Haaxma-Reiche, H; Holthuis, JJ; Mulder, NH; Postmus, PE; Sleijfer, DT; Sluiter, HJ; van Oort, WJ; Vencken, LM | 1 |
| Araya, Y; Dosaka, H; Isobe, H; Ito, M; Kawakami, Y; Miyamoto, H; Onodera, S; Shimizu, T; Takaoka, K | 1 |
| Edmundson, JM; Shiu, W; Steward, WP; Thatcher, N; Wilkinson, PM | 1 |
| Díaz Pérez, MA; García de Paredes, ML; González Larriba, JL; Montero García, JM; Ordóñez Gallego, A; Zamora, P | 1 |
| Gregor, A; Smyth, JF | 1 |
| Płuzańska, A; Robak, T | 1 |
| Fujita, K; Murayama, T; Sayama, T | 1 |
| Gozzelino, F; Lodico, D; Pescetti, G; Scagliotti, G | 1 |
| Fukuoka, M; Kimura, I; Kuraishi, Y; Ogawa, M; Ohnoshi, T; Ota, K; Oyama, A; Sanpi, K; Takada, M; Yoshida, S | 1 |
| Jameson, CH; Solanki, DL | 1 |
| Galligioni, E; Grigoletto, E; Santarossa, M; Tirelli, U; Trovo', MG; Tumolo, S; Veronesi, A; Zagonel, V | 1 |
| Brattain, MG; Long, BH; Musial, ST | 3 |
| Araya, Y; Dosaka, H; Inoue, S; Isobe, H; Ito, M; Kawakami, Y; Miyamoto, H; Mizuno, S; Takaoka, K | 1 |
| Broggini, M; Colombo, T; D'Incalci, M | 1 |
| Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Morasca, L; Torti, L; Ubezio, P; Vaghi, M | 1 |
| D'Incalci, M; Erba, E; Morasca, L; Vaghi, M | 1 |
| Gralla, RJ; Itri, LM | 1 |
| Eagan, RT | 1 |
| Klastersky, J; Longeval, E; Nicaise, C; Weerts, D | 1 |
| Berdel, WE; Diehl, V; Fink, U; Fischer, M; Graubner, M; Gropp, C; Liesenfeld, A; Mitrou, PS; Schmidt, M; Weissenfels, I | 1 |
| Klastersky, J; Longeval, E | 1 |
| Dombernowsky, P; Hansen, HH; Nissen, NI; Pedersen, AG | 1 |
| Casper, ES; Chapman, RA; Golbey, RB; Gralla, RJ; Itri, LM; Kelsen, DP | 1 |
| Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Torti, L | 1 |
| Casper, E; Chapman, R; Golbey, R; Gralla, R; Itri, L; Kelsen, D | 1 |
| Bianchi, C; Casali, W; Cogo, R; Marsoni, S; Morasca, L; Piazza, E; Pisoni, MB; Scapaticci, R; Vago, G | 1 |
| Anderson, G; Broderick, NJ; Cheong, CM; Peel, ET | 1 |
| Dicato, M | 1 |
| Creagan, ET; Eagan, RT; Kvols, LK | 1 |
| Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R; Kaplan, S; Obrecht, JP; Sonntag, R; Weber, W | 1 |
| Anderson, G; Bowyer, F; Williams, L | 1 |
| Cantwell, B | 1 |
| Jensen, PB | 1 |
| Gemba, K; Kiura, K; Matsumura, T; Moritaka, T; Ohnoshi, T; Segawa, Y; Shibayama, T; Tabata, M; Takigawa, N; Ueoka, H | 1 |
| Fujimoto, K; Kobunai, T; Nomura, M; Shibata, J; Sugimoto, Y; Terada, T; Wierzba, K; Yamada, Y; Yamashita, J; Yamazaki, R | 1 |
| Cordier, JF; Trillet-Lenoir, V | 1 |
| Bestry, I; Dańczak-Ginalska, Z; Rowińska-Zakrzewska, E; Starzyńska, T; Wiatr, E; Zych, J | 1 |
| Campling, BG; Jain, N; Lam, YM; Pym, J | 1 |
| Cavalli, F; D'Incalci, M; De Fusco, M; de Jong, J; Hanauske, A; Kaeser-Fröhlich, A; Pagani, O; Sessa, C; Zucchetti, M | 1 |
| Schacter, L | 1 |
| Goto, T; Kozuru, M; Kumagawa, M; Muta, K; Suehiro, Y; Uike, N | 1 |
| Choe, YH; Conover, CD; Greenwald, RB; Guan, S; Martinez, A; Pendri, A; Shum, KL; Wu, D; Yao, Z | 1 |
| Bastow, KF; Krishnan, P; Lee, KH; Tachibana, Y; Zhu, XK | 1 |
| Berhane, K; Boggaram, V; Margana, RK | 1 |
| Carr, DT; Eagan, RT; Frytak, S; Lee, RE; Rubin, J | 1 |
| Falkson, G; Falkson, HC; van den Bergh, JA; van der Merwe, AM; van Dyk, JJ; van Eden, EB | 1 |
| Beckmann, C; Flury, R; Frei, P; Holdener, E; Jungi, WF; Senn, HJ | 1 |
| Dombernowsky, P; Hansen, HH; Hansen, M; Hirsch, F | 1 |
| Weiss, RB | 1 |
| Ferguson, A; Hewitson, R; Levin, W; Sealy, R; Tucker, RD; Van Wyk, C | 1 |
| Baker, LH; Fraile, RJ; Samson, MK; Talley, RW | 1 |
| Fontana, JA | 1 |
| Bunn, PA; Ihde, DC; Radice, PA | 1 |
| Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD | 1 |
| Gautier, H; Huguenin, P; Lheritier, J; Mathé, G; Morin, P; Palangie, T; Parrot, R; Poisson, M; Pouillart, P | 1 |
| Brunner, KW; Cavalli, F; Jungi, F; Senn, HJ; Sonntag, RW | 1 |
| Crooke, ST; Issell, BF | 1 |
| Creagan, ET; Eagan, RT; Fleming, TR; Frytak, S; Ingle, JN; Kvols, LK; Rubin, J | 1 |
| Creagan, ET; Eagan, RT; Frytak, S; Ingle, JN; Kvols, LK; McMachon, RT; Rubin, J | 1 |
| Agusti, A; Estape, J; Lloret, JS; Milla, A; Palacin, A; Soriano, E | 1 |
| Brunner, KW; Cavalli, F; Hasler, E; Martin, J; Ryssel, HJ; Sonntag, RW; Tschopp, L | 1 |
| Barouh, M; Carpentier, Y; Cattan, A; Cattan, E; Pourny, C | 2 |
| Coldman, AJ; Klasa, RJ; Murray, N | 1 |
| D'Incalci, M; Figoli, F; Montaldo, PG; Sorio, R; Tirelli, U; Zanette, ML; Zucchetti, M | 1 |
| Babaya, K; Hirao, Y; Kubota, K; Natsume, O; Okajima, E; Ozono, S; Tsumatani, K; Yoshie, T | 1 |
| Briese, V; Straube, W; Szabo, DG; Than, GN; Willroth, PO | 1 |
| Heffner, JE; Milam, MG | 1 |
| Cellerino, R; Di Furia, L; Gramazio, A; Guidi, F; Menichetti, E; Tummarello, D | 1 |
| Barnes, S; Bartholomew, MJ; Dixon, R; Gordon, R; Harvey, HA; Lipton, A; Valdivia, D; Walker, B; Warzawski, N; White-Hershey, D | 1 |
| Roed, H; Vindeløv, LL | 1 |
| McVie, G; Muggia, FM | 1 |
| Bye, P; Crombie, C; Fox, RM; Green, D; Peretz, G; Raghavan, D; Stuart-Harris, R; Teriana, N; Tiver, K; Young, I | 1 |
| D'Incalci, M; Figoli, F; Lestuzzi, C; Monfardini, S; Sorio, R; Tirelli, U; Urso, R; Zanette, ML | 1 |
| Arkles, B; Cosolo, W; Morstyn, G; Zalcberg, JR; Zimet, AS | 1 |
| Bonardi, GM; Calciati, A; Donadio, M; Giaccone, G; Testore, F | 1 |
| Bearden, JD; Caldwell, RD; Case, LD; Cooper, MR; Jackson, DV; Muss, HB; Nelson, EC; Powell, BL; Richards, F; Zekan, PJ | 1 |
| Abad-Esteve, A; Fernández-Marcial, C; Moreno, I; Ribas Mundó, M; Rosell, R; Roselló, M | 1 |
| Bonardi, G; Calciati, A; Donadio, M; Giaccone, G; Testore, F | 1 |
| de Camargo, B; Lederman, H; Pinus, J; Saba, L | 1 |
| Brunner, KW; Cerny, T; Joss, RA; Pedrazzini, A | 1 |
| Berendsen, HH; Haaxma-Reiche, H; Postmus, PE | 1 |
| Anderson, PN; Baker, LH; Comis, RL; Daniels, JR; Einhorn, LH; Harvey, HA; Issell, BF; Lanzotti, VA; Lawson, RD; Wampler, GL | 1 |
| D'Incalci, M; Mangioni, C; Rossi, C; Roviaro, G; Sessa, C | 1 |
| Greco, FA; Grosh, WW; Hainsworth, JD; Hande, KR; Johnson, DH; Porter, LL; Wolff, SN | 1 |
| Klastersky, J; Sculier, JP; Stryckmans, P | 1 |
| Fukuoka, M; Hirano, M; Honma, T; Hoshino, A; Meguro, S; Nakamura, T; Ogawa, M; Shirakawa, S; Toki, H; Yoshida, S | 1 |
| Abratt, RP; Levin, W | 1 |
| Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ; Wittes, RE | 1 |
| Ahmedzai, S; Banham, S; Burnett, A; Cunningham, D; Dorward, A; Hutcheon, A; Kaye, S; Lucie, N; Soukop, M | 1 |
| Greco, FA; Hainsworth, JD; Hande, KR; Johnson, DH; Porter, LL; Wolff, SN | 1 |
| Bateman, NT; Bellamy, D; Calman, FM; Costello, J; Farebrother, M; Rubens, RD; Slevin, ML; Timothy, AR | 1 |
| Kimura, K; Niitani, H; Yamada, K | 1 |
| Tanneberger, S | 1 |
| Adelstein, DJ; Hines, JD | 1 |
| Danigel, H; Dellbrügge, J; Jungclas, H; Pflüger, KH; Schmidt, L | 1 |
| Chikata, E; Hara, K; Ito, F; Kado, M; Kanda, T; Matsui, Y; Nakayama, M; Ohshima, S; Sakai, S; Shimokata, K | 1 |
| Harvey, VJ; Joel, SP; Johnston, A; Slevin, ML; Wrigley, PF | 1 |
| Kimura, K; Niitani, H | 1 |
| Ahmedzai, S; Banham, SW; Cunningham, D; Dorward, A; Hutcheon, AH; Kaye, SB; Soukop, M; Stack, BR; Stevenson, RD; Tansey, P | 1 |
| Dang, P; Deboer, G; Evans, WK; Feld, R; Osoba, D; Shepherd, FA | 1 |
| Furuse, K | 1 |
| Harvey, VJ; Joel, SP; Johnston, A; Slevin, ML; Smythe, MM; Wrigley, PF | 1 |
| Hara, K; Kado, M; Kanda, T; Matsui, Y; Oshima, S; Shima, K; Shimokata, K; Takenaka, S | 1 |
| Bakaert, AB; De Broe, ME; Holthuis, JJ; Van de Vyver, FL; van Oort, WJ; Verleun, H | 1 |
| Livingston, RB | 1 |
| Bork, E; Dombernowsky, P; Hansen, HH; Hansen, M; Hansen, SW; Pedersen, AG | 1 |
| Hiraga, Y; Ito, T; Konno, K; Nagahama, F; Nakabayashi, T; Nakai, Y; Oizumi, K; Sato, M; Takebe, K; Tamura, M | 1 |
| Kinameri, K; Kurita, Y; Matsuura, N; Sano, K; Yokoyama, A | 1 |
| Hara, K; Ikebe, A; Ishizaki, T; Iwasaki, H; Kanda, T; Koteda, T; Nakano, M; Oka, M; Okuno, K; Tsutsumi, T | 1 |
| Choo, YC; Ma, HK; Wong, LC | 1 |
| Birch, R; Greco, FA; Sarma, P; Wolff, SN | 1 |
| Bentley, DP; Littlewood, TJ; Smith, AP | 1 |
| Eguchi, K; Morinaga, S; Saijo, N; Sakurai, M; Sano, T; Sasaki, Y; Shinkai, T; Suga, J; Tamura, T | 1 |
| Cummings, J; Cunningham, D; Forrest, GJ; McTaggart, L; Soukop, M; Stuart, JF | 1 |
| Brandes, A; Chiarion Sileni, V; De Besi, P; Fornasiero, A; Fosser, VP; Paccagnella, A; Pappagallo, GL; Salvagno, L; Simioni, G; Vinante, O | 1 |
| Bagatella, M; Bonardi, G; Calciati, A; Ciuffreda, L; Donadio, M; Ferrati, P; Giaccone, G | 1 |
| Drings, P; Gropp, C; Hans, K; Havemann, K; Heim, M; Holle, R; Klapsing, J; Manke, HG; Schroeder, M; Viktor, N | 1 |
| Coles, DT; Creagan, ET; Eagan, RT; Frytak, S; Jett, JL; Lee, RE; Richardson, RL | 1 |
| Abad-Esteve, A; Fernandez, C; Monras, P; Moreno, I; Morera, J; Ribas-Mundo, M; Rosell, R; Ruiz, J | 1 |
| Creger, RJ; Diaz, D; Lazarus, HM | 1 |
| Akiba, T; Eguchi, K; Fujiwara, Y; Miyamoto, K; Saijo, N; Sakurai, M; Sasaki, Y; Shinkai, T; Tamura, T; Uei, Y | 1 |
| Amato, G; Broggini, M; Colombo, T; D'Incalci, M; Erba, E; Vaghi, M | 1 |
| Nishikawa, K; Okamoto, K; Takahashi, K; Uchida, T | 1 |
| Christensen, IJ; Hansen, HH; Roed, H; Spang-Thomsen, M; Vindelov, LL | 1 |
| Calabresi, F; Greco, C; Sacchi, A; Zupi, G | 1 |
| Anderson, G; Payne, H | 1 |
| Bentley, DP; Littlewood, TJ; Spragg, BP | 1 |
| Buccheri, G; Curcio, A; Ferrigno, D; Mattalia, E; Vola, F | 1 |
| Hering, KG; Meydam, K | 1 |
| Nishikawa, K; Okamoto, K; Seki, T; Shibasaki, C; Takahashi, K; Uchida, T | 1 |
| Bertrand, M; Blayney, DW; Carr, BI; Cecchi, G; Doroshow, JH; Emont, E; Goldberg, D; Multhauf, P; Presant, C; Rappaport, D | 1 |
| Fairchild, C; Gottlieb, HE; Nudelman, A; Ruse, M | 1 |
| Hansen, HH; Muggia, FM; Selawry, OS | 1 |
| Anderson, JM; Hutchison, J | 1 |
| Clément, F | 1 |
| Ishii, Y; Kihara, A; Noguchi, H; Noto, J; Ohara, H | 1 |
| Assmann, H | 1 |
| Massei, V | 1 |
| Altaner, C; Svec, F | 1 |
| Beumer, HM; Porton, WM | 1 |
| Hatzenberger, H | 1 |
16 review(s) available for podophyllotoxin and Lung Neoplasms
| Article | Year |
|---|---|
Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): recent developments.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Docetaxel; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Microtubules; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Paclitaxel; Palliative Care; Podophyllotoxin; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Taxoids; Teniposide; Treatment Outcome; Vinblastine; Vinorelbine | 2003 |
[Etoposide. A new highly effective cytostatic agent in anaplastic small-cell bronchial carcinoma, other solid tumors and hemoblastoses].
Topics: Bronchial Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Small Cell; Cell Division; Choriocarcinoma; Etoposide; Female; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Podophyllotoxin; Pregnancy; Testicular Neoplasms; Uterine Neoplasms | 1981 |
Etoposide (VP-16) in the treatment of lung cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Time Factors | 1983 |
Management of small cell cancer: intensive chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Humans; Lomustine; Lung Neoplasms; Methotrexate; Podophyllotoxin; Procarbazine; Prognosis; Time Factors; Vincristine | 1984 |
The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review.
Topics: Animals; Antineoplastic Agents; Etoposide; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lung Neoplasms; Podophyllotoxin; Teniposide | 1980 |
Differential sensitivity patterns in small cell lung cancer cell lines: detection and circumvention of resistance to topoisomerase II targeting drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Humans; Lung Neoplasms; Phenotype; Podophyllotoxin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
[Origin of small cell lung cancers].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Neoplasm Metastasis; Platinum; Podophyllotoxin | 1993 |
Etoposide phosphate: what, why, where, and how?
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms; Organophosphorus Compounds; Podophyllotoxin | 1996 |
Small-cell carcinoma of the lung: therapeutic management.
Topics: Alkylating Agents; Altretamine; Antineoplastic Agents; Brain; Carcinoma, Small Cell; Doxorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Podophyllotoxin; Procarbazine; Vinblastine; Vincristine | 1978 |
VM 26 and VP 16-213: a comparative analysis.
Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1977 |
Etoposide (VP-16-213).
Topics: Adult; Animals; Bone Marrow; Cell Cycle; Child; Digestive System; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Rats | 1979 |
Dose-intensity meta-analysis of chemotherapy regimens in small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Meta-Analysis as Topic; Podophyllotoxin; Vincristine | 1991 |
A phase II study with teniposide (VM26) in patients with progressed or relapsed small cell lung cancer (SCLC).
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Retrospective Studies; Teniposide | 1989 |
Can human small-cell lung cancer cell lines be applied for optimizing chemotherapy?
Topics: Animals; Carcinoma, Small Cell; Colony-Forming Units Assay; DNA, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Nitrosourea Compounds; Platinum; Podophyllotoxin; Tumor Cells, Cultured | 1989 |
Etoposide (VP-16-213). Current status of an active anticancer drug.
Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution | 1985 |
Current chemotherapy of small cell lung cancer.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Complement Membrane Attack Complex; Complement System Proteins; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Mitomycin; Mitomycins; Podophyllotoxin; Procarbazine; Prognosis; Time Factors; Vincristine | 1986 |
27 trial(s) available for podophyllotoxin and Lung Neoplasms
| Article | Year |
|---|---|
A phase I pilot study of the insulin-like growth factor 1 receptor pathway modulator AXL1717 in combination with gemcitabine HCl and carboplatin in previously untreated, locally advanced, or metastatic non-small cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cohort Studies; Deoxycytidine; Female; Follow-Up Studies; Gemcitabine; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pilot Projects; Podophyllotoxin; Prognosis; Receptor, IGF Type 1; Tissue Distribution | 2015 |
A novel oral insulin-like growth factor-1 receptor pathway modulator and its implications for patients with non-small cell lung carcinoma: A phase I clinical trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Molecular Targeted Therapy; Neutropenia; Podophyllotoxin; Prospective Studies; Receptor, IGF Type 1; Signal Transduction; Treatment Outcome | 2016 |
Phase II randomized study of the IGF-1R pathway modulator AXL1717 compared to docetaxel in patients with previously treated, locally advanced or metastatic non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Disease Progression; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction; Survival Analysis; Taxoids; Treatment Outcome | 2017 |
VP-16-213 in combination chemotherapy with chest irradiation for small-cell lung cancer: a randomized trial of the Piedmont Oncology Association.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Vincristine | 1984 |
A controlled clinical trial testing two potentially non-cross-resistant chemotherapeutic regimens in small-cell carcinoma of the lung.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methotrexate; Podophyllotoxin; Procarbazine; Prognosis; Time Factors | 1981 |
VP-16-213 (etoposide): the mandrake root from Issyk-Kul.
Topics: Animals; Breast Neoplasms; Carcinoma, Small Cell; Cell Cycle; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dysgerminoma; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Mice; Podophyllotoxin | 1982 |
Doxorubicin, Cyclophosphamide and VP16-213 (ACE) in the treatment of small cell lung cancer.
Topics: Adult; Aged; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Lack of potentiation of vincristine-induced neurotoxicity by VP-16-213.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nervous System Diseases; Podophyllotoxin; Random Allocation; Vincristine | 1983 |
[New antineoplastic drugs of the podophyllotoxin derivative group].
Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1983 |
[The role of radiotherapy in combined treatment of limited small cell lung cancer in relation to results of induction chemotherapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Remission Induction; Survival Rate; Vincristine | 1995 |
Clinical and pharmacokinetic study of oral NK611, a new podophyllotoxin derivative.
Topics: Administration, Oral; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neutropenia; Podophyllotoxin; Thrombocytopenia | 1996 |
VP-16-213 versus polychemotherapy in patients with advanced small cell lung cancer.
Topics: Adult; Aged; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Podophyllotoxin; Prognosis; Vincristine | 1976 |
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide | 1979 |
Treatment of malignant gliomas and brain metastases in adults using a combination of adriamycine, VM 26, and CCNU. Results of a type II trial.
Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Glioma; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Podophyllotoxin; Teniposide | 1977 |
VP-16-213 monotherapy for remission induction of small cell lung cancer: a randomized trial using three dosage schedules.
Topics: Carcinoma; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin | 1978 |
Dose-intensity meta-analysis of chemotherapy regimens in small-cell carcinoma of the lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation; Etoposide; Humans; Lung Neoplasms; Meta-Analysis as Topic; Podophyllotoxin; Vincristine | 1991 |
Chemotherapy plus RA233 in the treatment of oat cell lung cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Double-Blind Method; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mopidamol; Podophyllotoxin; Prospective Studies; Pyrimidines; Random Allocation; Vincristine | 1989 |
Improvement of long-term survival in extensive small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prognosis; Random Allocation; Vincristine | 1988 |
Etoposide (VP-16-213). Current status of an active anticancer drug.
Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution | 1985 |
[Phase I clinical study of NK 171 (etoposide)].
Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Podophyllotoxin | 1985 |
Randomized dose-response evaluation of etoposide in small cell carcinoma of the lung: a Southeastern Cancer Study Group Trial.
Topics: Carcinoma, Small Cell; Clinical Trials as Topic; Dose-Response Relationship, Drug; Etoposide; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin; Random Allocation | 1986 |
Cisplatin plus vindesine versus cisplatin plus VP16 versus doxorubicin plus cytoxan in non-small-cell carcinoma of the lung. A randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Random Allocation; Vindesine | 1986 |
Two randomized trials for alternating polychemotherapy of small cell lung cancer.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Humans; Ifosfamide; Lomustine; Lung Neoplasms; Methotrexate; Podophyllotoxin; Random Allocation; Sex Factors; Smoking; Time Factors; Vincristine; Vindesine | 1986 |
A randomized study comparing platinum, doxorubicin, and VP-16 with platinum, 4'-epidoxorubicin, and VP-16 in patients with non-small-cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Epirubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Platinum; Podophyllotoxin; Random Allocation | 1987 |
Response rate and toxicity of etoposide (VP-16) in squamous carcinoma of the lung: report from the Lung Cancer Treatment Study Group.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin | 1985 |
Clinical studies with a new podophyllotoxin derivative, epipodophyllotoxin, 4'-demethyl-9-(4,6-O-2-thenylidine- -D-glucopyranoside) (NSC-122819).
Topics: Aged; Antineoplastic Agents; Astrocytoma; Clinical Trials as Topic; Esophageal Neoplasms; Evaluation Studies as Topic; Fibroblasts; Glycosides; Humans; Hypotension; Lactones; Leiomyosarcoma; Leukopenia; Liver Neoplasms; Lung Neoplasms; Melanoma; Middle Aged; Mitosis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Structure-Activity Relationship; Thiophenes; Thrombocytopenia | 1971 |
Long-term chemotherapy for cancer of the lung.
Topics: Aged; Carcinoma, Squamous Cell; Catheterization; Clinical Trials as Topic; Fluorouracil; Humans; Injections, Intravenous; Long-Term Care; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum | 1968 |
170 other study(ies) available for podophyllotoxin and Lung Neoplasms
| Article | Year |
|---|---|
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1991 |
Synthesis and antitumor activity of structural analogues of the epipodophyllotoxins.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Etoposide; Humans; Indans; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured | 1991 |
Synthesis and cytotoxicity of novel lignans.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Humans; Lignans; Lung Neoplasms; Tumor Cells, Cultured | 1995 |
Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cattle; Cell Division; Central Nervous System Neoplasms; Colonic Neoplasms; Female; Humans; Leukemia; Lung Neoplasms; Molecular Structure; Polymers; Quinolones; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1994 |
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Synthesis and biological evaluation of new podophyllic aldehyde derivatives with cytotoxic and apoptosis-inducing activities.
Topics: Aldehydes; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma; Molecular Structure; Podophyllotoxin; Tumor Cells, Cultured | 2010 |
Self-Assembly of Podophyllotoxin-Loaded Lipid Bilayer Nanoparticles for Highly Effective Chemotherapy and Immunotherapy via Downregulation of Programmed Cell Death Ligand 1 Production.
Topics: Animals; Apoptosis; Cell Line, Tumor; Down-Regulation; Immunologic Factors; Immunotherapy; Ligands; Lipid Bilayers; Lung Neoplasms; Mice; Nanoparticles; Podophyllotoxin; Tumor Microenvironment | 2022 |
Cationic Nanoparticulate System for Codelivery of MicroRNA-424 and Podophyllotoxin as a Multimodal Anticancer Therapy.
Topics: Animals; B7-H1 Antigen; Cell Line, Tumor; Ecosystem; Lung Neoplasms; Mice; MicroRNAs; Podophyllotoxin; Tumor Microenvironment | 2022 |
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Phenylacetates; Phosphatidylinositol 3-Kinases; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Tubulin | 2023 |
Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Molecular Docking Simulation; Molecular Targeted Therapy; Podophyllotoxin; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met | 2021 |
Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; gamma-Synuclein; Gene Knockdown Techniques; Glucose; Humans; Inflammation; Insulin-Like Growth Factor I; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Proteins; Podophyllotoxin; Receptor, IGF Type 1; Tumor Necrosis Factor-alpha; Tumor Stem Cell Assay | 2021 |
Deoxypodophyllotoxin Inhibits Cell Growth and Induces Apoptosis by Blocking EGFR and MET in Gefitinib-Resistant Non-Small Cell Lung Cancer.
Topics: Antineoplastic Agents; Apiaceae; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Podophyllotoxin; Proto-Oncogene Proteins c-met; Signal Transduction | 2021 |
Selective targeting and therapy of metastatic and multidrug resistant tumors using a long circulating podophyllotoxin nanoparticle.
Topics: Animals; Antineoplastic Agents; Carboxymethylcellulose Sodium; Cell Line, Tumor; Delayed-Action Preparations; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Nanoparticles; Ovarian Neoplasms; Podophyllotoxin; Polyethylene Glycols | 2017 |
Novel hybrids of podophyllotoxin and formononetin inhibit the growth, migration and invasion of lung cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 8; Cattle; Cell Line, Tumor; Cell Movement; Drug Screening Assays, Antitumor; Humans; Isoflavones; Lung Neoplasms; Mice; Molecular Docking Simulation; Podophyllotoxin; Rats; Tubulin; Tubulin Modulators; Vimentin | 2019 |
A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Damage; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stress; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mice; Microtubules; Mitosis; Models, Biological; Podophyllotoxin; Protein Multimerization; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Deoxypodophyllotoxin triggers necroptosis in human non-small cell lung cancer NCI-H460 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Culture Techniques; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Necrosis; Podophyllotoxin; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2013 |
DPMA, a deoxypodophyllotoxin derivative, induces apoptosis and anti-angiogenesis in non-small cell lung cancer A549 cells.
Topics: Adenosine; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Line, Tumor; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Neovascularization, Physiologic; Podophyllotoxin; Signal Transduction; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2013 |
Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Humans; Lung Neoplasms; Mice; Podophyllotoxin; Receptor, IGF Type 1 | 2015 |
Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism.
Topics: Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Survival; Centrosome; Cyclin B1; Cyclin-Dependent Kinases; Enzyme Activation; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Lung Neoplasms; MCF-7 Cells; Microtubules; Mitosis; Podophyllotoxin; Receptor, IGF Type 1; Receptors, Somatomedin; RNA Interference; Signal Transduction; Time Factors; Transfection; Tubulin; Xenograft Model Antitumor Assays | 2014 |
Podophyllotoxin acetate triggers anticancer effects against non-small cell lung cancer cells by promoting cell death via cell cycle arrest, ER stress and autophagy.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Microtubules; Podophyllotoxin | 2015 |
Investigation of the mechanism and apoptotic pathway induced by 4β cinnamido linked podophyllotoxins against human lung cancer cells A549.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cytochromes c; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Molecular Structure; Podophyllotoxin; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species | 2015 |
Newly synthesized podophyllotoxin derivative, LJ12, induces apoptosis and mitotic catastrophe in non-small cell lung cancer cells in vitro.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Methionine; Microtubules; Mitosis; Neoplasm Proteins; Podophyllotoxin | 2016 |
Γ-Ionizing radiation-induced activation of the EGFR-p38/ERK-STAT3/CREB-1-EMT pathway promotes the migration/invasion of non-small cell lung cancer cells and is inhibited by podophyllotoxin acetate.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Gamma Rays; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Podophyllotoxin; Signal Transduction; Transcription Factors | 2016 |
Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis.
Topics: A549 Cells; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Lung Neoplasms; Microtubules; Mitogen-Activated Protein Kinases; Podophyllotoxin; Topoisomerase Inhibitors | 2016 |
Tertiary amine mediated targeted therapy against metastatic lung cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mice, Inbred Strains; Molecular Structure; Molecular Targeted Therapy; Piperazines; Podophyllotoxin; Propylamines; Structure-Activity Relationship; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system.
Topics: Animals; Binding, Competitive; Biogenic Polyamines; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Delivery Systems; Etoposide; Female; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays | 2008 |
[Comparison of the biodistribution and PET imaging with (11)C-PDT and (18)F-FDG in the mouse model of lung adenocarcinoma].
Topics: Adenocarcinoma; Animals; Carbon Radioisotopes; Cell Line, Tumor; Fluorodeoxyglucose F18; Kidney; Liver; Lung Neoplasms; Mice; Myocardium; Podophyllotoxin; Positron-Emission Tomography; Tissue Distribution | 2010 |
QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells.
Topics: Adenocarcinoma; Antigens, Neoplasm; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Caspase 3; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Flow Cytometry; Humans; Lung Neoplasms; Piperidines; Podophyllotoxin; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2012 |
Remission of brain metastases from small-cell lung cancer after high-dose chemotherapy.
Topics: Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1984 |
Phase II trial of etoposide in previously treated small cell carcinoma of the lung.
Topics: Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Podophyllotoxin | 1984 |
[Cisplatin, adriamycin and VP-16 (CAV) in the treatment of small cell carcinoma of the lung].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1984 |
The feasibility of adjuvant surgery in limited-stage small cell carcinoma: a prospective evaluation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prospective Studies; Vincristine | 1984 |
Feasibility of high dose VP 16-213 as single agent or in combination with cyclophosphamide and autologous bone marrow transplantation (ABMT).
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Germ Cell and Embryonal; Podophyllotoxin | 1984 |
Phase II study of teniposide in small cell carcinoma of the lung.
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1984 |
Etoposide: a new anti-cancer agent.
Topics: Animals; Drug Evaluation; Etoposide; Female; Humans; Kinetics; Lung Neoplasms; Male; Mitosis; Neoplasms; Podophyllotoxin; Testicular Neoplasms | 1981 |
Cis-dichlorodiammineplatinum (II) and VP 16-213 combination chemotherapy for non-small cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1981 |
VP-16-213 therapy in patients with small-cell carcinoma of the lung after failure on combination chemotherapy.
Topics: Adult; Aged; Carcinoma, Small Cell; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1981 |
Possible enhancement of vincristine neuropathy by VP-16.
Topics: Aged; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Electrophysiology; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Muscles; Nervous System Diseases; Peripheral Nerves; Podophyllotoxin; Vincristine | 1982 |
Combination chemotherapy for metastatic brain tumors.
Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Doxorubicin; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Nitrosourea Compounds; Podophyllotoxin; Prognosis; Teniposide; Tomography, X-Ray Computed | 1981 |
Treatment of small cell lung cancer with a combination of VP16-213 and cyclophosphamide with cisplatin or radiotherapy.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Time Factors | 1982 |
VP16-213 combined with cis-platinum (CDDP) in the treatment of small cell carcinoma of the lung (SCLC).
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Enhanced radiation reaction following combination chemotherapy for small cell carcinoma of the lung, possibly secondary to VP16-213.
Topics: Aged; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Radiotherapy; Vincristine | 1982 |
VP16-213 in combined modality treatment of small cell carcinoma of the lung.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Methotrexate; Nausea; Neoplasm Staging; Podophyllotoxin | 1982 |
Small-cell bronchogenic carcinoma--primary and relapse therapy with etoposide (VP-16), methotrexate and CCNU.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Drug Therapy, Combination; Etoposide; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Podophyllotoxin | 1982 |
Etoposide after ACO treatment for small-cell bronchogenic carcinoma.
Topics: Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Vincristine | 1982 |
Etoposide as single agent and in combination chemotherapy of bronchogenic carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Combination cis-platinum and etoposide in small-cell lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Combination chemotherapy of small-cell bronchogenic carcinoma with etoposide (VP-16), ifosfamide and vindesine (VPIV), and with adriamycin, cis-platinum and vincristine (APO).
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Podophyllotoxin; Vinblastine; Vincristine; Vindesine | 1982 |
VP-16 plus cyclophosphamide in the treatment of advanced lung cancer.
Topics: Adult; Aged; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Probability | 1983 |
Etoposide in small cell lung cancer resistant to prior chemotherapy.
Topics: Carcinoma, Small Cell; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1983 |
High-dose etoposide as single-agent chemotherapy for small cell carcinoma of the lung.
Topics: Adult; Aged; Carcinoma, Small Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1983 |
VP-16 alone and in combination with cisplatin in previously treated patients with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Thrombocytopenia; Time Factors | 1984 |
Chemotherapy of refractory germ cell cancer with Etoposide.
Topics: Adolescent; Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Choriocarcinoma; Cisplatin; Dysgerminoma; Etoposide; Humans; Lung Neoplasms; Male; Mesonephroma; Nausea; Neoplasms, Germ Cell and Embryonal; Podophyllotoxin; Retroperitoneal Neoplasms; Testicular Neoplasms | 1983 |
Treatment of small cell lung cancer with VP-16, vincristine, doxorubicin (Adriamycin), cyclophosphamide (EVAC), and high-dose chest radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Humans; Leukopenia; Lung Neoplasms; Nausea; Nervous System Diseases; Podophyllotoxin; Vincristine | 1983 |
Penetration of VP 16-213 into cerebrospinal fluid after high-dose intravenous administration.
Topics: Adult; Aged; Blood-Brain Barrier; Brain Neoplasms; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Humans; Injections, Intravenous; Lung Neoplasms; Middle Aged; Podophyllotoxin; Tomography, X-Ray Computed | 1984 |
Etoposide (VP 16-213; VePesid).
Topics: Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Podophyllotoxin; Testicular Neoplasms | 1984 |
[Effects of oral etoposide in small cell carcinoma of the lung].
Topics: Administration, Oral; Adult; Aged; Capsules; Carcinoma, Small Cell; Etoposide; Humans; Leukopenia; Lung Neoplasms; Male; Nausea; Podophyllotoxin; Thrombocytopenia | 1984 |
Etoposide infusions for treatment of metastatic lung cancer.
Topics: Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Etoposide; Follow-Up Studies; Humans; Infusions, Parenteral; Kinetics; Lung Neoplasms; Neoplasm Metastasis; Podophyllotoxin | 1984 |
[Treatment of bronchopulmonary small cell carcinoma with a combination of cyclophosphamide and VP-16].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1984 |
[Effect of etoposide for pulmonary metastases from urogenital tract cancer].
Topics: Adenocarcinoma; Administration, Oral; Aged; Carcinoma, Transitional Cell; Etoposide; Humans; Infusions, Parenteral; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prostatic Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms | 1984 |
Etoposide by oral route in the treatment of unresectable non-small cell lung cancer.
Topics: Administration, Oral; Aged; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1984 |
[Phase I study of an oral administration of VP 16-213].
Topics: Administration, Oral; Adult; Aged; Capsules; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Lymphoma; Male; Middle Aged; Podophyllotoxin | 1983 |
Stevens-Johnson syndrome associated with etoposide therapy.
Topics: Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Stevens-Johnson Syndrome | 1983 |
cis-platinum and etoposide combination chemotherapy of advanced non-oat cell bronchogenic carcinoma.
Topics: Adult; Aged; Carcinoma, Bronchogenic; Cisplatin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1983 |
Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship.
Topics: Adenocarcinoma; Cell Line; Cell Survival; DNA; DNA Repair; Etoposide; Humans; Kinetics; Lung Neoplasms; Podophyllotoxin; Structure-Activity Relationship; Teniposide | 1984 |
[Etoposide effect on cell cycle kinetics of a human lung cancer cell line].
Topics: Cell Count; Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA, Neoplasm; Etoposide; Flow Cytometry; Humans; Lung Neoplasms; Podophyllotoxin | 1984 |
Activity and pharmacokinetics of teniposide in Lewis lung carcinoma-bearing mice.
Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Half-Life; Kinetics; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Tissue Distribution | 1983 |
Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma.
Topics: Animals; Cell Cycle; Cell Line; DNA, Neoplasm; Etoposide; Flow Cytometry; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin | 1983 |
In vitro cytotoxicity of VP 16 on primary tumor and metastasis of Lewis lung carcinoma.
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; Podophyllotoxin; Thymidine | 1982 |
A review of etoposide in patients with non-small-cell lung cancer (NSCLC).
Topics: Cisplatin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin | 1982 |
Etoposide alone and in combination with cyclophosphamide, adriamycin and cis-platinum in patients with Mo and Mi non-small-cell lung cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Podophyllotoxin | 1982 |
Etoposide and cis-platinum in non-small-cell bronchogenic carcinoma.
Topics: Carcinoma, Bronchogenic; Cisplatin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin | 1982 |
Treatment of inoperable non-small-cell bronchogenic carcinoma with etoposide and cis-platinum.
Topics: Carcinoma, Bronchogenic; Cisplatin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Combination chemotherapy with cisplatin and etoposide in bronchogenic squamous cell carcinoma and adenocarcinoma. A study by the EORTC lung cancer working party (Belgium).
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin | 1982 |
Phase II trial of VP-16-213 in non-small-cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bone Marrow; Carcinoma, Squamous Cell; Digestive System; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
Pharmacokinetics of VP16-213 in Lewis lung carcinoma bearing mice.
Topics: Animals; Etoposide; Kinetics; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Podophyllotoxin; Tissue Distribution | 1982 |
Phase II trial of VP16-213 in non-small cell lung cancer (NSCLC).
Topics: Adult; Aged; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
VP16-213 and cyclophosphamide in non oat cell bronchogenic carcinoma.
Topics: Carcinoma, Bronchogenic; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Podophyllotoxin | 1982 |
Etoposide--an effective single drug for treating bronchogenic carcinoma.
Topics: Bone Marrow; Carcinoma, Bronchogenic; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1982 |
[Etoposide: VP-16].
Topics: Etoposide; Humans; Lung Neoplasms; Lymphoma; Neoplasms; Podophyllotoxin | 1982 |
Preliminary study of the combination, dianhydrogalactitol, cis-diaminedichloroplatinum (II), and VP-16-213 in patients with advanced cancer.
Topics: Brain Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Dianhydrogalactitol; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pilot Projects; Podophyllotoxin; Sugar Alcohols | 1981 |
[Chemotherapy of non-small-cell bronchial cancer with a combination of Cis-diamminedichloroplatinum (II) and VP 16-213].
Topics: Adenocarcinoma; Body Weight; Carcinoma; Carcinoma, Squamous Cell; Cisplatin; Drug Therapy, Combination; Etoposide; Humans; Leukocyte Count; Lung Neoplasms; Podophyllotoxin; Vomiting | 1981 |
Oral VP-16-213 in advanced bronchogenic carcinoma and toxic effects when combined with methotrexate.
Topics: Bone Marrow Diseases; Doxorubicin; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Methotrexate; Podophyllotoxin; Vincristine | 1981 |
Oral VP-16-213 in advanced bronchogenic carcinoma.
Topics: Bone Marrow Diseases; Carcinoma, Bronchogenic; Drug Combinations; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Vincristine | 1981 |
[In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.
Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Mechanisms of resistance of human small cell lung cancer lines selected in VP-16 and cisplatin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Chloride; Carcinoma, Small Cell; Cell Line; Chlorides; Cisplatin; Cross Reactions; DNA; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Lung Neoplasms; Metallothionein; Platinum Compounds; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Vinca Alkaloids | 1996 |
Therapy-related acute myeloid leukemia with minimal myeloid differentiation (AML-M0) associated with a t(11;19)(q23;p13.3) translocation.
Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chromosomes, Human, Pair 11; Cyclophosphamide; DNA-Binding Proteins; Doxorubicin; Gene Rearrangement; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Myeloid-Lymphoid Leukemia Protein; Podophyllotoxin; Proto-Oncogenes; Transcription Factors; Translocation, Genetic; Vincristine; Zinc Fingers | 1997 |
Drug delivery of anticancer agents: water soluble 4-poly (ethylene glycol) derivatives of the lignan, podophyllotoxin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Leukemia P388; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Nuclear Magnetic Resonance, Biomolecular; Podophyllotoxin; Polyethylene Glycols; Solubility; Transplantation, Heterologous; Tumor Cells, Cultured; Water | 1999 |
Characterization of human lung cancer cells resistant to 4'-O-demethyl-4beta-(2"-nitro-4"-fluoroanilino)-4-desoxypodophyllotoxin , a unique compound in the epipodophyllotoxin antitumor class.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Drug Interactions; Drug Resistance, Neoplasm; Genes, MDR; Humans; KB Cells; Lung Neoplasms; Membrane Proteins; Phosphorylation; Podophyllotoxin; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Verapamil | 2000 |
Characterization of rabbit SP-B promoter region responsive to downregulation by tumor necrosis factor-alpha.
Topics: Adenocarcinoma; Animals; Cell Line; Cell Nucleus; Cytosol; DNA-Binding Proteins; Gene Expression Regulation; Hepatocyte Nuclear Factor 3-alpha; Humans; Lung Neoplasms; Mutagenesis, Site-Directed; NF-kappa B; Nuclear Proteins; Podophyllin; Podophyllotoxin; Promoter Regions, Genetic; Proteolipids; Pulmonary Surfactants; Rabbits; Thyroid Nuclear Factor 1; Transcription Factors; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
A clinical trial of the oral form of 4'-demethyl-epipodophyllotoxin-beta-D ethylidene glucoside (NSC 141540) VP 16-213.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Glucosides; Humans; Leukemia, Myeloid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mesothelioma; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Urinary Bladder Neoplasms | 1975 |
Epipodophyllotoxin (VP 16-213) in the treatmetn of diffuse histiocytic lymphoma.
Topics: Adult; Aged; Carcinoma, Small Cell; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Prospective Studies; Remission, Spontaneous | 1975 |
[Therapeutic experiences using the new podophyllotoxin derivative VP 16-213 in malignant human tumors].
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Prostatic Neoplasms; Remission, Spontaneous | 1975 |
Treatment of small cell anaplastic carcinoma of the lung with the oral solution of VP-16-213 (NSC 141540, 4'-demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside).
Topics: Administration, Oral; Aged; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Solutions | 1977 |
Chemotherapy of small cell carcinoma of the lung with V.P. 16-213.
Topics: Bone Marrow; Carcinoma, Small Cell; Disability Evaluation; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Podophyllotoxin; Recurrence; Remission, Spontaneous; Time Factors | 1978 |
VM26 (NSC-122819): a clinical study in advanced cancer of the lung and ovary.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Thrombocytopenia | 1978 |
Radiation recall associated with VP-16-213 therapy.
Topics: Carcinoma, Small Cell; Erythema; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Radiation Injuries; Radiation-Sensitizing Agents; Time Factors | 1979 |
VP-16, cyclophosphamide, adriamycin and cis-platinum (V:CAP-I) in patients with metastatic adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Remission, Spontaneous; Time Factors; Vomiting | 1979 |
VP-16-213 chemotherapy for advanced squamous cell carcinoma and adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Time Factors | 1978 |
VP 16-213 (VP 16) and cyclophosphamide in the treatment of primitive lung cancer in phase M 1.
Topics: Adult; Aged; Bone Marrow; Cyclophosphamide; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prednisone; Remission, Spontaneous; Vincristine | 1979 |
[VP 16-213 in combination with endoxan, methotrexate and oncovin as polychemotherapy for bronchogenic carcinoma].
Topics: Adenocarcinoma; Anaplasia; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Etoposide; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis; Podophyllotoxin; Remission, Spontaneous; Vincristine | 1977 |
Effect of hemostasis modifiers of the activity of VP 16 213 on Lewis lung carcinoma.
Topics: Animals; Aspirin; Etoposide; Hemostasis; Heparin; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Transplantation, Homologous | 1977 |
Antimetastasis effect of two derivatives of epiposophyllotoxin in mice.
Topics: Animals; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Solvents; Teniposide; Time Factors | 1976 |
Pharmacokinetics of intrapleural versus intravenous etoposide (VP 16) and teniposide (VM 26) in patients with malignant pleural effusion.
Topics: Aged; Etoposide; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Pleural Effusion; Podophyllotoxin; Teniposide | 1990 |
[Complete remission obtained in advanced testicular cancer treated by etoposide (NK-171)].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Etoposide; Humans; Lung Neoplasms; Lymph Node Excision; Male; Peplomycin; Podophyllotoxin; Teratoma; Testicular Neoplasms; Vincristine | 1986 |
[Levels of tumor markers (orosomucoid, pregnancy-associated alpha 2-glycoprotein, pregnancy protein-1, placental specific-tissue protein 10, placental specific-tissue protein 12, alpha 1-fetoprotein) in the serum of patients with bronchial carcinoma].
Topics: Aged; alpha-Fetoproteins; Carcinoma, Bronchogenic; Female; Glycoproteins; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Proteins; Lung Neoplasms; Male; Middle Aged; Orosomucoid; Podophyllin; Podophyllotoxin; Pregnancy Proteins | 1986 |
Sarcoid-like hilar and mediastinal lymphadenopathy in a patient with metastatic testicular cancer.
Topics: Adult; Biopsy, Needle; Bleomycin; Cisplatin; Diagnosis, Differential; Granuloma; Humans; Lung Neoplasms; Lymph Nodes; Lymphoma; Male; Orchiectomy; Podophyllotoxin; Sarcoidosis; Teratoma; Testicular Neoplasms | 1987 |
Treatment strategies in relation to drug action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Chemotherapy for small cell lung cancer: induction and reinduction with VOCA.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Vincristine | 1987 |
Pharmacokinetics of VM 26 given intrapericardially or intravenously in patients with malignant pericardial effusion.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Pericardial Effusion; Pericardium; Podophyllotoxin; Teniposide | 1987 |
Flare responses in small cell carcinoma of the lung.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Carcinoma, Small Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Podophyllotoxin; Radionuclide Imaging | 1988 |
Teniposide (VM26): an effective treatment for brain metastases of small cell carcinoma of the lung.
Topics: Aged; Brain Neoplasms; Carcinoma, Small Cell; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide; Thrombocytopenia | 1988 |
[VP-16, vincristine, adriamycin and cyclophosphamide (EVAC) in patients with small-cell lung cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Time Factors; Vincristine | 1988 |
Teniposide in the treatment of small-cell lung cancer: the influence of prior chemotherapy.
Topics: Aged; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prognosis; Teniposide | 1988 |
Intrascrotal metastasis from Wilms' tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Combined Modality Therapy; Dactinomycin; Doxorubicin; Genital Neoplasms, Male; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Podophyllotoxin; Scrotum; Vincristine; Wilms Tumor | 1988 |
Unexpected high toxicity in a phase II study of teniposide (VM-26) in elderly patients with untreated small cell lung cancer (SCLC).
Topics: Aged; Aged, 80 and over; Carcinoma, Small Cell; Drug Evaluation; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1988 |
Podophyllotoxins for brain metastases of small cell lung cancer.
Topics: Brain Neoplasms; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1988 |
Multicenter Phase II trial of etoposide in refractory small cell lung cancer.
Topics: Carcinoma, Small Cell; Drug Evaluation; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Multi-Institutional Systems; Nausea; Podophyllotoxin; Vomiting | 1985 |
Pharmacokinetics of etoposide in gestochoriocarcinoma.
Topics: Choriocarcinoma; Etoposide; Female; Half-Life; Humans; Kinetics; Lung; Lung Neoplasms; Myometrium; Podophyllotoxin; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms | 1985 |
Extensive-stage small-cell bronchogenic carcinoma: intensive induction chemotherapy with high-dose cyclophosphamide plus high-dose etoposide.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Podophyllotoxin; Thrombocytopenia; Vincristine | 1985 |
Late intensification in small-cell lung cancer: a phase I study of high doses of cyclophosphamide and etoposide with autologous bone marrow transplantation.
Topics: Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carcinoma, Small Cell; Cyclophosphamide; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Podophyllotoxin | 1985 |
[Phase II study of VP-16 (capsule) in solid tumors. A cooperative study].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Capsules; Carcinoma, Hepatocellular; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin; Soft Tissue Neoplasms; Thrombocytopenia | 1985 |
Probable cure of small cell carcinoma of the lung by etoposide.
Topics: Carcinoma, Small Cell; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Radiography; Smoking | 1985 |
The role of VP-16 in the treatment of small-cell lung cancer: studies of the West of Scotland Lung Cancer Group.
Topics: Carcinoma, Small Cell; Cyclophosphamide; Drug Resistance; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Verapamil | 1985 |
High-dose etoposide (VP-16) in small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin | 1985 |
Single-dose etoposide in combination with vincristine and doxorubicin in the treatment of small-cell lung cancer (SCLC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Vincristine | 1985 |
[Antineoplastic chemotherapy for bronchial carcinoma].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Humans; Lomustine; Lung Neoplasms; Methotrexate; Podophyllotoxin; Procarbazine; Vinblastine; Vincristine; Vindesine | 1985 |
Bone marrow morphologic changes after combination chemotherapy including VP-16.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Erythrocytes; Etoposide; Female; Hematopoiesis; Humans; Lung Neoplasms; Male; Mitosis; Podophyllotoxin; Vincristine | 1985 |
Drug monitoring of etoposide (VP16-213). I. A combined method of liquid chromatography and mass spectrometry.
Topics: Californium; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Computers; Etoposide; Half-Life; Humans; Kinetics; Lung Neoplasms; Mass Spectrometry; Podophyllotoxin | 1985 |
[A phase II study of oral VP-16 in primary lung cancer].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Anorexia; Capsules; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1985 |
The effect of food and concurrent chemotherapy on the bioavailability of oral etoposide.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Carcinoma, Small Cell; Drug Interactions; Etoposide; Food; Humans; Kinetics; Lung Neoplasms; Podophyllotoxin | 1985 |
[A phase II study of NK171 (etoposide)].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Alopecia; Anorexia; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1985 |
High-dose cyclophosphamide and VP 16 as late dosage intensification therapy for small cell carcinoma of lung.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Follow-Up Studies; Humans; Lung Neoplasms; Podophyllotoxin | 1985 |
VP-16 and cisplatin as first-line therapy for small-cell lung cancer.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Small Cell; Cisplatin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Podophyllotoxin; Thrombocytopenia; Time Factors | 1985 |
[A phase II study of etoposide (NK 171) in small cell lung cancer--comparison of results between intravenous administration and oral administration].
Topics: Administration, Oral; Adult; Aged; Alopecia; Anorexia; Carcinoma, Small Cell; Drug Evaluation; Etoposide; Fatigue; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1985 |
Variable bioavailability following repeated oral doses of etoposide.
Topics: Adult; Biological Availability; Carcinoma, Small Cell; Drug Administration Schedule; Etoposide; Humans; Kinetics; Lung Neoplasms; Mesothelioma; Podophyllotoxin; Time Factors | 1985 |
[A phase II study of etoposide (VP-16) injection in primary lung cancer by cooperative study group].
Topics: Adenocarcinoma; Adult; Aged; Alopecia; Anorexia; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Injections; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1986 |
Pharmacokinetic evaluation of increasing dosages of etoposide in a chronic hemodialysis patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Kidney Failure, Chronic; Kinetics; Lung Neoplasms; Male; Mathematics; Middle Aged; Podophyllotoxin; Renal Dialysis | 1985 |
Teniposide (VM-26), an overlooked highly active agent in small-cell lung cancer. Results of a phase II trial in untreated patients.
Topics: Aged; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Humans; Lung Neoplasms; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide | 1986 |
[A phase II study of intravenous VP-16-213 in small cell and non-small cell carcinoma of the lung].
Topics: Adult; Aged; Alopecia; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin | 1986 |
[Phase II study of etoposide in patients with lung cancer, with special reference to small cell carcinoma].
Topics: Adenocarcinoma; Aged; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1986 |
[Phase II study of VP-16 in patients with primary bronchogenic carcinoma, with special reference to small cell carcinoma--a multi-institutional cooperative study].
Topics: Administration, Oral; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin | 1986 |
Primary oral etoposide therapy in gestational trophoblastic disease. An update.
Topics: Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin; Etoposide; Female; Humans; Hydatidiform Mole; Hysterectomy; Lung Neoplasms; Neoplasm Recurrence, Local; Podophyllotoxin; Pregnancy; Risk; Trophoblastic Neoplasms; Uterine Neoplasms; Vaginal Neoplasms | 1986 |
DNA breakage in human lung carcinoma cells and nuclei that are naturally sensitive or resistant to etoposide and teniposide.
Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Small Cell; Cell Division; Cell Nucleus; Cells, Cultured; DNA; DNA, Single-Stranded; Drug Resistance; Etoposide; Humans; Intercalating Agents; Lung Neoplasms; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1986 |
High-dose etoposide with autologous bone marrow transplantation as initial treatment of small cell lung cancer--a negative report.
Topics: Bone Marrow Diseases; Bone Marrow Transplantation; Carcinoma, Small Cell; Combined Modality Therapy; Etoposide; Humans; Lung Neoplasms; Middle Aged; Mouth Mucosa; Podophyllotoxin; Stomatitis; Transplantation, Autologous | 1986 |
A case of small cell lung cancer successfully treated with VM26.
Topics: Aged; Carcinoma, Small Cell; Drug Evaluation; Humans; Lung Neoplasms; Male; Podophyllotoxin; Teniposide | 1986 |
Etoposide: a pharmacokinetic profile including an assessment of bioavailability.
Topics: Administration, Oral; Biological Availability; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Hodgkin Disease; Humans; Injections, Intravenous; Kinetics; Lung Neoplasms; Lymphoma; Male; Neoplasms; Podophyllotoxin | 1986 |
Teniposide in the treatment of non-small cell lung carcinoma.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1987 |
Cyclophosphamide, etoposide, and infusion cisplatin in refractory small cell lung cancer. A preliminary report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Vincristine | 1987 |
Simple method for the administration of high-dose etoposide during autologous bone marrow transplantation.
Topics: Adult; Aged; Bone Marrow Transplantation; Drug Evaluation; Etoposide; Humans; Infusions, Parenteral; Leukemia; Lung Neoplasms; Middle Aged; Podophyllotoxin | 1986 |
A case of adenocarcinoma of the lung which was successfully treated by chemotherapy with patient survival without recurrence for more than three years.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Podophyllotoxin; Smoking; Vincristine; Vindesine | 1987 |
Comparison between VP 16 and VM 26 in Lewis lung carcinoma of the mouse.
Topics: Animals; Body Weight; Cell Count; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Kinetics; Leukocyte Count; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Podophyllotoxin; Teniposide | 1986 |
[Combination of etoposide with cisplatin or cyclophosphamide in the treatment of mouse Lewis lung carcinoma].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Drug Synergism; Etoposide; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Podophyllotoxin | 1986 |
The effect of the two epipodophyllotoxin derivatives etoposide (VP-16) and teniposide (VM-26) on cell lines established from patients with small cell carcinoma of the lung.
Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Line; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Etoposide; Lung Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Etoposide prior to cis-diamminedichloroplatinum in combination chemotherapy: in vitro and in vivo studies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Lung Neoplasms; Mice; Mice, Inbred C57BL; Podophyllotoxin | 1985 |
Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide.
Topics: Adenocarcinoma; Aminoacridines; Amsacrine; Cells, Cultured; DNA; DNA Repair; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide | 1985 |
When is autologous bone marrow transplantation safe after high-dose treatment with etoposide?
Topics: Adult; Aged; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; Etoposide; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Neutrophils; Podophyllotoxin; Reticulocytes; Time Factors; Transplantation, Autologous | 1985 |
MACC (methotrexate, doxorubicin, cyclophosphamide and lomustine) versus cis-platinum and etoposide in the treatment of advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Podophyllotoxin; Time Factors | 1986 |
[Combined low-dose radiation and adriblastin therapy of lung metastases].
Topics: Adenocarcinoma; Aged; Carcinoma; Cobalt Radioisotopes; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Hysterectomy; Lung Neoplasms; Male; Methotrexate; Middle Aged; Podophyllin; Podophyllotoxin; Radioisotope Teletherapy; Uterine Neoplasms | 1985 |
[The antitumor activity of intraperitoneally- or orally-administered etoposide in animals and its administration-schedule dependency].
Topics: Adenocarcinoma; Administration, Oral; Animals; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Drug Administration Schedule; Etoposide; Female; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Podophyllotoxin | 1985 |
Phase II trial of etoposide, vincristine, and high-dose cisplatin in advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Vincristine | 1985 |
Studies in sugar chemistry. VII. Glucuronides of podophyllum derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Drug Screening Assays, Antitumor; Glucuronates; Humans; Leukemia P388; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Plants, Medicinal; Plants, Toxic; Podophyllum; Tumor Cells, Cultured | 1997 |
[The chemotherapy of cancer].
Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Sarcoma, Ewing; Thiotepa; Vincristine | 1967 |
[Clinical findings in podophyllotoxin derivatives (SP-I-SP-G) in malignant tumors].
Topics: Adult; Aged; Animals; Antineoplastic Agents; Female; Humans; Leukemia, Myeloid; Lung Neoplasms; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Stomach Neoplasms | 1968 |
[Combination treatment of pulmonary metastasis using radiotherapy and chemotherapy].
Topics: Adenocarcinoma; Adult; Breast Neoplasms; Cobalt Isotopes; Female; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Radioisotope Teletherapy; Thyroid Neoplasms | 1969 |
[Observations on the therapy of primary cancer of the lung (sample research on 100 subjects treated)].
Topics: Antineoplastic Agents; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum | 1967 |
[The effect of Proresid on the growth and formation of metastases of the RBI-sarcoma in rats].
Topics: Animals; Antineoplastic Agents; Lung Neoplasms; Mitosis; Neoplasm Metastasis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Rats; Sarcoma, Experimental | 1968 |
[Effect of cytostatics on tumor cells].
Topics: Bronchial Neoplasms; Carcinoma; Cyclophosphamide; Humans; Lung Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Triaziquone | 1968 |
[On diagnostic and therapeutic problems of the metastasizing breast carcinoma].
Topics: Adult; Aged; Austria; Breast Neoplasms; Diagnosis, Differential; Gold Colloid, Radioactive; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Plants, Medicinal; Plants, Toxic; Pleural Effusion; Pleural Neoplasms; Podophyllin; Podophyllum | 1969 |