Page last updated: 2024-08-21

podophyllotoxin and Leukemia

podophyllotoxin has been researched along with Leukemia in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	52 (65.00)	18.7374
1990's	13 (16.25)	18.2507
2000's	6 (7.50)	29.6817
2010's	8 (10.00)	24.3611
2020's	1 (1.25)	2.80

Authors

Authors	Studies
Hamel, E; Kuo, SC; Lednicer, D; Lee, KH; Li, L; Lin, CM; Wang, HK; Wu, TS	1
Boykin, DW; Hu, L; Jiang, JD; Li, JN; Li, ZR; Qu, J	1
Chen, F; Chen, Y; Lin, Y; Wang, J; Zhang, L; Zhang, Z	1
Cho, SD; Choi, SJ; Shin, JA; Yu, HJ	1
Dünweber, A; Fridthjof, KS; Friis, LS; Gørløv, JS; Kampmann, P; Kjeldsen, L; Moser, C; Møller, T; Nexø, C; Nørskov, KH; Welinder, PC	1
Benabbou, N; Bordu, C; Faussat, AM; Marie, JP; Mirshahi, M; Mirshahi, P; Soria, J; Tang, R; Therwath, A	1
Hasinoff, BB; Patel, D; Wu, X; Yadav, AA; Yalowich, JC	1
Bogucka-Kocka, A; Cieśla, Ł; Kocki, J; Kubrak, T; Och, A; Och, M; Pecio, Ł; Stochmal, A	1
Allodji, RS; Benabdennebi, A; Chavaudra, J; Dayet, F; de Vathaire, F; Deutsch, E; Diallo, I; Diop, F; Haddy, N; Jackson, A; Labbé, M; Le Deley, MC; Lefkopoulos, D; Llanas, D; Oberlin, O; Rubino, C; Schwartz, B; Veres, C; Vu Bezin, J	1
Flint, M; Haces, A; Jeedimalla, N; Minond, D; Roche, SP; Smith, L	1
Chen, Y; Jing, YX; Qi, SN; Song, LJ	1
Langebrake, C; Reinhardt, D; Ritter, J	1
Bresters, D; Broekhuizen, AJ; Faircloth, GT; Jimeno, J; Kaaijk, P; Kaspers, GJ	1
Qi, SN; Ueda, T; Wang, ZR; Yoshida, A	1
WATERMAN, N	1
Seiter, K	1
Bremner, P; Heinrich, M; Ionkova, I; Konstantinov, S; Momekov, G; Vasilev, N; Zaharieva, M	1
Dahl, GV; Look, AT; Mauer, AM; Rivera, G	1
Bowman, WP; Dahl, GV; Evans, WE; Kalwinsky, D; Look, AT; Rivera, G	1
Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R; Ryssel, HJ; Sonntag, RW	1
Kennedy, BJ; Raghavan, D; Vogelzang, NJ	1
Płuzańska, A; Robak, T	1
Hunstein, W; Körbling, M	1
Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ	1
Hattori, K; Ito, K; Kobayashi, S; Nakamura, S; Nakanishi, J; Ohtake, S; Yoshida, T	1
Etcubanas, E; Evans, W; Hayes, FA; Hutson, P; Sinkule, JA	1
Arakawa, S; Esumi, N; Imashuku, S	1
Dubovsky, DW; Jacobs, P; Wood, L	1
Dubovsky, DW; Jacobs, P; Kernoff, LM	1
Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA	1
Cavalli, F; Sauter, C; Varini, M	1
Gershanovich, ML; Kondrat'ev, VB; Kondrat'eva, NA; Lebedev, VN; Vygovskaia, IaI	1
Allen, PD; Castenskiold, EC; Coldwell, RD; Collins, PW; Goldstone, AH; Kelsey, SM; Makin, HL; Newland, AC; Side, LE	1
Kobayashi, K; Ratain, MJ	2
Ellis, M; Lishner, M; Ravid, M	1
Fraser, MJ; Ireland, CM; Papaioannou, A; Pittman, SM; Tynan, SJ	1
Anttila, VJ; Isomäki, HA; Kauppi, M; Savolainen, HA	1
Chen, PM; Chiou, TJ; Fang, FS; Hsieh, RK; Liu, JH; Tung, SL; Tzeng, CH; Wang, WS; Yen, CC	1
Blair, IA; Cheung, NK; Felix, CA; Lange, BJ; Lovett, BD; Nowell, PC; Rebbeck, TR; Walker, AH; Williams, TM; Winick, NJ	1
Barta, A; Batai, A; Kelemen, E; Lengyel, L; Paloczi, K; Petranyi, GG; Sipos, A; Torbagyi, E	1
Comelli, A; Massimo, L	1
Bunn, PA; Ihde, DC; Radice, PA	1
Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD	1
Bleyer, WA; Chard, RL; Hammond, D; Krivit, W	1
Crooke, ST; Issell, BF	1
Crooke, ST; Gutierrez, ML	1
Illiger, HJ; Labedzki, L	1
Dubovsky, D; Jacobs, P; Kernoff, L	1
Batz, K; Brunner, KW; Cavalli, F; Ryssel, HJ; Sonntag, RW	1
Donaldson, MH; Rosenstock, JG	1
Comay, S; Dubovsky, D; Hougaard, M; Jacobs, P	1
Dubovsky, D; Jacobs, P	1
Chessells, JM; Hawkins, MM; Kingston, JE; Marsden, HB; Potok, MH; Stovall, MA; Wilson, LM	1
Hawkins, MM	1
Beck, WT; Danks, MK; Fernandes, DJ	1
McVie, G; Muggia, FM	1
Beck, WT; Cirtain, MC; Danks, MK; Felsted, RL; Safa, AR; Suttle, DP; Trent, JM; Wolverton, JS	1
Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ; Wittes, RE	1
White, JC; Wright, SE	1
Beck, WT; Pearce, HL; Zamora, JM	1
Creger, RJ; Diaz, D; Lazarus, HM	1
Andreeff, M; Ciobanu, N; Paietta, E; Papenhausen, P; Wiernik, PH	1
Fortner, CL; King, SA; Leyland-Jones, B; O'Dwyer, PJ	1
Cockerill, K; Culbert, S; Hester, J; Horwitz, L; Jagannath, S; Keating, M; Larry, N; Spitzer, G; Vellekoop, L; Zander, AR	1
Abromowitch, M; Evans, WE; Hayes, FA; Rivera, GK; Rodman, JH; Sinkule, JA	1
Chan, HY; Lewis, JP; Meyers, FJ	1
Abe, T; Kariyone, S; Maekawa, I; Maekawa, T; Miura, A; Miura, Y; Moriyama, Y; Shibata, A; Wakui, A; Yoshida, Y	1
Gomis, F; Lorenzo, I; Martín-Aragonés, G; Martínez, JA; Marty, ML; Rafecas, FJ; Sanz, G; Sanz, MA	1
Jacobs, P	1
Kimura, K; Yamada, K; Yoshida, T	1
Arakawa, S; Esumi, N; Imashuku, S; Todo, S	1
Hines, LH; Rathmell, JP; White, JC	1
Amiel, JL; Céoara, B; de Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Oldham, R; Pouillart, P; Rosenfeld, C; Schneider, M; Schwarzenberg, L; Steresco-Musset, M; Weiner, R	1
Amiel, JL; De Vassal, F; Hayat, M; Jasmin, C; Mathé, G; Misset, JL; Musset, M; Oldham, R; Pouillart, P; Rosenfeld, C; Schneider, M; Schwarzenberg, L; Weiner, R	1
Lemmel, EM; Motycka, K; Nouza, K; Soucek, J	1
Amiel, JL; Beyer, HP; de Vassal, F; Fajbisowicz, S; Hayat, M; Jasmin, C; Mathé, G; Pouillart, P; Schneider, M; Schwarzenberg, L; Weiner, R	1
van Os, FH	1
Cardinali, G; Gedda, L	1

Reviews

12 review(s) available for podophyllotoxin and Leukemia

Article	Year
Minimising the long-term adverse effects of childhood leukaemia therapy. Drug safety, 2002, Volume: 25, Issue:15 Topics: Alkylating Agents; Anthracyclines; Antimetabolites; Antineoplastic Agents; Asparaginase; Asparagine; Cardiovascular Diseases; Child; Clinical Trials as Topic; Glucocorticoids; Gonadal Disorders; Humans; Leukemia; Leukemia, Myeloid, Acute; Osteonecrosis; Podophyllotoxin; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tretinoin; Vinca Alkaloids	2002
Toxicity of the topoisomerase II inhibitors. Expert opinion on drug safety, 2005, Volume: 4, Issue:2 Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases	2005
[Etoposide. A new highly effective cytostatic agent in anaplastic small-cell bronchial carcinoma, other solid tumors and hemoblastoses]. Deutsche medizinische Wochenschrift (1946), 1981, Aug-28, Volume: 106, Issue:35 Topics: Bronchial Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Small Cell; Cell Division; Choriocarcinoma; Etoposide; Female; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Podophyllotoxin; Pregnancy; Testicular Neoplasms; Uterine Neoplasms	1981
In vitro chemoseparation as part of autologous bone marrow transplantation (ABMT) in hematologic malignancy. Blut, 1984, Volume: 48, Issue:4 Topics: Acute Disease; Animals; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Leukemia; Lymphoma; Mechlorethamine; Neoplastic Stem Cells; Photosensitivity Disorders; Podophyllotoxin; Pyrimidinones; Rats; Transplantation, Autologous	1984
Teniposide: a review of 12 years of experience. Cancer treatment reports, 1984, Volume: 68, Issue:12 Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide	1984
Pharmacodynamics and long-term toxicity of etoposide. Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl Topics: Child; Etoposide; Humans; Leukemia; Leukemia, Myeloid, Acute; Male; Neoplasms; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Testicular Neoplasms	1994
A comparative analysis of alkylating agent and epipodophyllotoxin-related leukemias. Leukemia & lymphoma, 1993, Volume: 11, Issue:1-2 Topics: Alkylating Agents; DNA Damage; Humans; Leukemia; Neoplasms, Second Primary; Podophyllotoxin	1993
VM 26 and VP 16-213: a comparative analysis. Cancer, 1977, Volume: 40, Issue:1 Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms	1977
Etoposide (VP-16-213). Cancer treatment reviews, 1979, Volume: 6, Issue:2 Topics: Adult; Animals; Bone Marrow; Cell Cycle; Child; Digestive System; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Rats	1979
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C. Cancer treatment reviews, 1979, Volume: 6, Issue:3 Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide	1979
Etoposide (VP-16-213). Current status of an active anticancer drug. The New England journal of medicine, 1985, Mar-14, Volume: 312, Issue:11 Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution	1985
[Plants with cytostatic effect]. Il Farmaco; edizione scientifica, 1970, Volume: 25, Issue:6 Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Cell Transformation, Neoplastic; Colchicine; Colchicum; DNA; Drug Synergism; Glutamine; Glycolysis; Humans; Leukemia; Mercaptopurine; Methotrexate; Mitosis; Neoplasms; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Purines; Pyrimidines; RNA; Steroids; Vincristine	1970

Trials

14 trial(s) available for podophyllotoxin and Leukemia

Article	Year
VP-16-213 (etoposide): the mandrake root from Issyk-Kul. The American journal of medicine, 1982, Volume: 72, Issue:1 Topics: Animals; Breast Neoplasms; Carcinoma, Small Cell; Cell Cycle; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dysgerminoma; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Mice; Podophyllotoxin	1982
[New antineoplastic drugs of the podophyllotoxin derivative group]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Jan-03, Volume: 38, Issue:1 Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms	1983
Teniposide: a review of 12 years of experience. Cancer treatment reports, 1984, Volume: 68, Issue:12 Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide	1984
[Phase II study of etoposide (NK 171) in advanced hematological malignancies]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8 Topics: Administration, Oral; Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Leukemia; Leukopenia; Lymphoma; Male; Middle Aged; Nausea; Podophyllotoxin; Prednisolone; Thrombocytosis; Vincristine	1984
In adult acute nonlymphoblastic leukaemia extended maintenance chemotherapy has no benefit. American journal of hematology, 1984, Volume: 16, Issue:3 Topics: Acute Disease; Adolescent; Adult; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Podophyllotoxin; Prognosis	1984
Navoban (tropisetron, ICS 205-930) and dexamethasone combination in the prevention of vomiting for patients receiving preconditioning high-dose chemotherapy before marrow transplantation. Japanese journal of clinical oncology, 1998, Volume: 28, Issue:2 Topics: Adolescent; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Carmustine; Child; Cyclophosphamide; Cytarabine; Dexamethasone; Dizziness; Drug Therapy, Combination; Female; Headache; Heartburn; Humans; Indoles; Leukemia; Male; Melphalan; Middle Aged; Multiple Myeloma; Podophyllotoxin; Transplantation Conditioning; Tropisetron; Vomiting; Whole-Body Irradiation	1998
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies. Cancer treatment reports, 1979, Volume: 63, Issue:8 Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide	1979
Phase II study of VM-26 in acute leukemia, neuroblastoma, and other refractory childhood malignancies: a report from the Children's Cancer Study Group. Cancer treatment reports, 1979, Volume: 63, Issue:6 Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Neoplasms; Neuroblastoma; Podophyllotoxin; Remission, Spontaneous; Teniposide	1979
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C. Cancer treatment reviews, 1979, Volume: 6, Issue:3 Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide	1979
Phase I-II trial of VM-26 (NSC-122819) in the treatment of children with late-stage leukemia. Cancer treatment reports, 1976, Volume: 60, Issue:3 Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Podophyllotoxin; Teniposide	1976
Etoposide (VP-16-213). Current status of an active anticancer drug. The New England journal of medicine, 1985, Mar-14, Volume: 312, Issue:11 Topics: Animals; Carcinoma, Small Cell; Clinical Trials as Topic; DNA; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Etoposide; Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Male; Mice; Podophyllotoxin; Testicular Neoplasms; Tissue Distribution	1985
The epipodophyllotoxin VP16-213 in combination chemotherapy for adults with acute nonlymphoblastic leukaemia. Haematology and blood transfusion, 1985, Volume: 29 Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Doxorubicin; Etoposide; Humans; Leukemia; Podophyllotoxin; Thioguanine	1985
Epipodophyllotoxin VP 16213 in treatment of acute leukaemias, haematosarcomas, and solid tumours. British medical journal, 1973, Jul-28, Volume: 3, Issue:5873 Topics: Adult; Aged; Agranulocytosis; Alopecia; Antineoplastic Agents; Female; Glycosides; Hodgkin Disease; Humans; Lactones; Leukemia; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Nausea; Neoplasms; Neutrophils; Podophyllotoxin; Remission, Spontaneous; Thrombocytopenia; Vomiting	1973
Two epipodophyllotoxin derivatives, VM 26 and VP 16213, in the treatment of leukemias, hematosarcomas, and lymphomas. Cancer, 1974, Volume: 34, Issue:4 Topics: Adolescent; Adult; Aged; Alopecia; Child; Child, Preschool; Clinical Trials as Topic; Digestive System; Drug Evaluation; Female; Glycosides; Hodgkin Disease; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukopenia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Pleural Effusion; Podophyllotoxin; Thrombocytopenia	1974

Other Studies

57 other study(ies) available for podophyllotoxin and Leukemia

Article	Year
Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. Journal of medicinal chemistry, 1994, Apr-15, Volume: 37, Issue:8 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cattle; Cell Division; Central Nervous System Neoplasms; Colonic Neoplasms; Female; Humans; Leukemia; Lung Neoplasms; Molecular Structure; Polymers; Quinolones; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	1994
3-(2'-Bromopropionylamino)-benzamides as novel S-phase arrest agents. Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24 Topics: Animals; Benzamides; Brain; Bromides; Cattle; Cell Line, Tumor; Humans; Leukemia; Molecular Structure; Propylamines; S Phase; Structure-Activity Relationship; Tubulin	2007
Design, synthesis and evaluation of the multidrug resistance-reversing activity of pyridine acid esters of podophyllotoxin in human leukemia cells. Bioorganic & medicinal chemistry letters, 2016, 09-15, Volume: 26, Issue:18 Topics: Cell Line, Tumor; Drug Design; Drug Resistance, Multiple; Esters; Humans; Inhibitory Concentration 50; Leukemia; MAP Kinase Signaling System; Podophyllotoxin; Pyridines	2016
Podophyllotoxin reduces the aggressiveness of human oral squamous cell carcinoma through myeloid cell leukemia‑1. International journal of molecular medicine, 2023, Volume: 52, Issue:5 Topics: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Leukemia; Mouth Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Myeloid Cells; Podophyllotoxin; Squamous Cell Carcinoma of Head and Neck	2023
Systematic patient involvement for homebased outpatient administration of complex chemotherapy in acute leukemia and lymphoma. British journal of haematology, 2018, Volume: 181, Issue:5 Topics: Acute Disease; Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Female; Humans; Infusion Pumps; Leukemia; Lymphoma; Male; Melphalan; Middle Aged; Outpatients; Podophyllotoxin	2018
A subset of bone marrow stromal cells regulate ATP-binding cassette gene expression via insulin-like growth factor-I in a leukemia cell line. International journal of oncology, 2014, Volume: 45, Issue:4 Topics: ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Proliferation; Daunorubicin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Insulin-Like Growth Factor I; Leukemia; Mesenchymal Stem Cells; Podophyllotoxin; Receptor, IGF Type 1; Receptors, Somatomedin	2014
Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNA. Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia; Molecular Docking Simulation; Mustard Compounds; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors	2014
Study of cytotoxic activity, podophyllotoxin, and deoxypodophyllotoxin content in selected Juniperus species cultivated in Poland. Pharmaceutical biology, 2015, Volume: 53, Issue:6 Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Drugs, Chinese Herbal; Humans; Juniperus; Leukemia; Plant Leaves; Podophyllotoxin; Poland; Trypan Blue	2015
Risk of Subsequent Leukemia After a Solid Tumor in Childhood: Impact of Bone Marrow Radiation Therapy and Chemotherapy. International journal of radiation oncology, biology, physics, 2015, Nov-01, Volume: 93, Issue:3 Topics: Adolescent; Analysis of Variance; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Bone Marrow; Case-Control Studies; Child; Child, Preschool; Confidence Intervals; Female; Humans; Infant; Leukemia; Leukemia, Radiation-Induced; Male; Neoplasms; Neoplasms, Second Primary; Odds Ratio; Platinum Compounds; Podophyllotoxin; Radiation Dosage	2015
Multicomponent assembly of 4-aza-podophyllotoxins: A fast entry to highly selective and potent anti-leukemic agents. European journal of medicinal chemistry, 2015, Dec-01, Volume: 106 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Leukemia; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Trypan Blue	2015
Reversal of mdr1-mediated multidrug resistance in human leukemia cells by a new spin-labeled derivative of podophyllotoxin. Die Pharmazie, 2010, Volume: 65, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Cell Line, Tumor; DNA Fragmentation; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; G2 Phase; Humans; K562 Cells; Leukemia; Podophyllotoxin; Spin Labels; Tetrazolium Salts; Thiazoles	2010
In vitro cytotoxicity of aplidin and crossresistance with other cytotoxic drugs in childhood leukemic and normal bone marrow and blood samples: a rational basis for clinical development. Leukemia, 2003, Volume: 17, Issue:7 Topics: Antineoplastic Agents; Blood Cells; Bone Marrow; Carnitine; Case-Control Studies; Cell Survival; Child; Deoxycytidine; Depsipeptides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Peptides, Cyclic; Podophyllotoxin	2003
GP7 can induce apoptotic DNA fragmentation of human leukemia cells through caspase-3-dependent and -independent pathways. International journal of molecular medicine, 2004, Volume: 13, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Carnitine; Caspase 3; Caspase Inhibitors; Caspases; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Leukemia; Oligopeptides; Podophyllotoxin; Time Factors	2004
On some chemotherapeutic experiments with podophyllotoxin. Acta physiologica et pharmacologica Neerlandica, 1950, Volume: 1, Issue:4 Topics: Humans; Leukemia; Neoplasms; Podophyllin; Podophyllotoxin	1950
Cytotoxic activity of a podophyllotoxin-like lignan from Linum tauricum Willd. Neoplasma, 2005, Volume: 52, Issue:5 Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; DNA Fragmentation; Dose-Response Relationship, Drug; Flax; HeLa Cells; HL-60 Cells; Humans; Leukemia; NF-kappa B; Plant Preparations; Podophyllotoxin	2005
Clinical and cell kinetic studies of the effects of the epipodophyllotoxin VP16-213 during therapy of refractory acute nonlymphocytic leukemia. Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3 Topics: Acute Disease; Adolescent; Adult; Azacitidine; Cell Division; Child; Child, Preschool; DNA, Neoplasm; Drug Resistance; Etoposide; Female; Flow Cytometry; Humans; Infant; Kinetics; Leukemia; Male; Mitosis; Podophyllotoxin	1982
Single-agent and combination chemotherapy with etoposide in the acute leukemias of childhood. Cancer treatment reviews, 1982, Volume: 9 Suppl Topics: Acute Disease; Azacitidine; Child; Drug Therapy, Combination; Etoposide; Humans; Leukemia; Podophyllotoxin; Prednisone; Vincristine	1982
Pharmacokinetics of etoposide (VP16) in children and adolescents with refractory solid tumors. Cancer research, 1984, Volume: 44, Issue:7 Topics: Adolescent; Adult; Child; Child, Preschool; Cisplatin; Etoposide; Female; Humans; Kinetics; Leukemia; Male; Metabolic Clearance Rate; Neoplasms; Podophyllotoxin	1984
[VP 16-213 in the treatment of acute leukemia in childhood]. Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:3 Topics: Acute Disease; Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Podophyllotoxin	1983
The University of Cape Town leukaemia centre: the first 5 years. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Mar-15, Volume: 57, Issue:11 Topics: Academic Medical Centers; Acute Disease; Bone Marrow Transplantation; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukapheresis; Leukemia; Podophyllotoxin; South Africa; Transplantation, Homologous	1980
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer. Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3 Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide	1982
Etoposide in the treatment of acute leukemia in adults. Cancer treatment reviews, 1982, Volume: 9 Suppl Topics: Acute Disease; Adult; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Humans; Leukemia; Podophyllotoxin	1982
[Use of VM 26 (epipodophyllotoxin) in treating acute leukemias and lymphomas in the adult]. Problemy gematologii i perelivaniia krovi, 1981, Volume: 26, Issue:7 Topics: Acute Disease; Adult; Drug Evaluation; Hodgkin Disease; Humans; Leukemia; Lymphoma; Podophyllotoxin; Teniposide; Time Factors	1981
Functional hyperactivity of monocytes after bone marrow transplantation: possible relevance for the development of post-transplant complications or relapse. Bone marrow transplantation, 1995, Volume: 15, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Biopterins; Bone Marrow Transplantation; Busulfan; Carmustine; Cells, Cultured; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease Susceptibility; Female; Graft vs Host Disease; Hepatic Veno-Occlusive Disease; Humans; Leukemia; Lymphoma; Male; Melphalan; Middle Aged; Monocytes; Neopterin; Podophyllotoxin; Respiratory Burst; Superoxides; Tumor Necrosis Factor-alpha; Whole-Body Irradiation	1995
Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis. Journal of cell science, 1996, Volume: 109 ( Pt 9) Topics: Apoptosis; Cell Nucleus; Cytosol; DNA Fragmentation; Endonucleases; Endoplasmic Reticulum; Etoposide; Exonucleases; Humans; Kinetics; Leukemia; Molecular Weight; Podophyllotoxin; Tumor Cells, Cultured	1996
Leukaemia during podophyllotoxin treatment in a patient with juvenile chronic arthritis. Scandinavian journal of rheumatology, 1996, Volume: 25, Issue:5 Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Glycosides; Humans; Leukemia; Lignans; Neoplasms, Second Primary; Podophyllotoxin	1996
Association of CYP3A4 genotype with treatment-related leukemia. Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-27, Volume: 95, Issue:22 Topics: Adolescent; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Chromosome Mapping; Chromosomes, Human, Pair 11; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA-Binding Proteins; Ethnicity; Female; Histone-Lysine N-Methyltransferase; Humans; Karyotyping; Leukemia; Male; Mixed Function Oxygenases; Myeloid-Lymphoid Leukemia Protein; Neoplasms; Neoplasms, Second Primary; Phenotype; Podophyllotoxin; Proto-Oncogenes; Racial Groups; Transcription Factors; United States	1998
Haemopoietic cell transplantation activity and results: a single institution experience. Bone marrow transplantation, 1998, Volume: 22 Suppl 4 Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Hungary; Leukemia; Melphalan; Podophyllotoxin; Recurrence; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation	1998
[New drugs for the therapy of acute leukemia]. Minerva medica, 1975, Jul-28, Volume: 66, Issue:52 Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Guanazole; Humans; Leukemia; Lomustine; Peptichemio; Podophyllotoxin; Razoxane; Zinostatin	1975
[Successful therapy of chronic myelomonocytic leukemia with vp 16-213 (author's transl)]. Blut, 1979, Volume: 38, Issue:5 Topics: Age Factors; Aged; Chronic Disease; Etoposide; Granulocytes; Humans; Leukemia; Male; Monocytes; Podophyllotoxin	1979
Rapid remission induction in adult acute non-lymphoblastic leukaemia. European journal of cancer, 1978, Volume: 14, Issue:11 Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Sepsis; Time Factors	1978
[Initial results with a epipodophyllotoxin derivative VP 16-213 in the treatment of acute leukemia]. Schweizerische medizinische Wochenschrift, 1975, Feb-22, Volume: 105, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aged; Chemical Phenomena; Chemistry; Chronic Disease; Drug Evaluation; Female; Glucosides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous	1975
Letter: Epipodophyllotoxin VP 16213 in acute non-lymphoblastic leukaemia. British medical journal, 1975, Feb-15, Volume: 1, Issue:5954 Topics: Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Podophyllotoxin; Thiophenes	1975
Letter: Treatment of acute leukaemia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Nov-01, Volume: 49, Issue:46 Topics: Acute Disease; Cytarabine; Doxorubicin; Drug Therapy, Combination; Humans; Leukemia; Methotrexate; Podophyllotoxin	1975
New perspectives on the toxicity of etoposide. Seminars in oncology, 1992, Volume: 19, Issue:6 Suppl 13 Topics: Bone Marrow Diseases; Etoposide; Humans; Leukemia; Neoplasms, Second Primary; Podophyllotoxin	1992
Epipodophyllotoxins, alkylating agents, and radiation and risk of secondary leukaemia after childhood cancer. BMJ (Clinical research ed.), 1992, Apr-11, Volume: 304, Issue:6832 Topics: Alkylating Agents; Antineoplastic Agents; Bone Marrow; Case-Control Studies; Child; Cohort Studies; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Leukemia; Neoplasms, Second Primary; Podophyllotoxin; Radiotherapy; Risk Factors	1992
Secondary leukaemia after epipodophyllotoxins. Lancet (London, England), 1991, Nov-30, Volume: 338, Issue:8779 Topics: Case-Control Studies; Child; Humans; Leukemia; Neoplasms, Second Primary; Podophyllotoxin	1991
Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA. Biochemistry, 1990, May-01, Volume: 29, Issue:17 Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Nucleus; Crithidia; DNA; DNA Topoisomerases, Type II; Drug Resistance; Humans; Leukemia; Podophyllotoxin; Teniposide; Tumor Cells, Cultured	1990
Treatment strategies in relation to drug action. NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide	1987
Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells. Cancer research, 1987, Oct-15, Volume: 47, Issue:20 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Banding; Chromosomes, Human, Pair 13; Colchicine; Dactinomycin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Membrane Glycoproteins; Molecular Weight; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Verapamil; Vinblastine; Vinca Alkaloids	1987
Membrane ordering effects of the anticancer agent VM-26. Biochimica et biophysica acta, 1986, Dec-16, Volume: 863, Issue:2 Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cholesterol; Cyclic N-Oxides; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Etoposide; Humans; Leukemia; Lipid Bilayers; Liposomes; Male; Membrane Lipids; Mice; Podophyllotoxin; Spin Labels; Teniposide	1986
Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Molecular pharmacology, 1988, Volume: 33, Issue:4 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry, Physical; Chloroquine; Computer Simulation; Doxorubicin; Drug Resistance; Humans; Leukemia; Naphthacenes; Podophyllotoxin; Quinacrine; Verapamil; Vinca Alkaloids	1988
Simple method for the administration of high-dose etoposide during autologous bone marrow transplantation. Cancer treatment reports, 1986, Volume: 70, Issue:6 Topics: Adult; Aged; Bone Marrow Transplantation; Drug Evaluation; Etoposide; Humans; Infusions, Parenteral; Leukemia; Lung Neoplasms; Middle Aged; Podophyllotoxin	1986
Etoposide as an in vitro purging agent for the treatment of acute leukemias and lymphomas in conjunction with autologous bone marrow transplantation. Experimental hematology, 1986, Volume: 14, Issue:7 Topics: Bone Marrow; Bone Marrow Transplantation; Colony-Forming Units Assay; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Microscopy, Electron; Podophyllotoxin; Transplantation, Autologous	1986
Hypersensitivity reactions to teniposide (VM-26): an analysis. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:8 Topics: Adolescent; Adult; Aged; Bibliographies as Topic; Blood Pressure; Brain Neoplasms; Child; Child, Preschool; Data Collection; Drug Evaluation; Drug Hypersensitivity; Edema; Humans; Hypersensitivity, Immediate; Infant; Leukemia; Male; Middle Aged; Neuroblastoma; Podophyllotoxin; Surveys and Questionnaires; Teniposide; Urticaria	1986
High dose cyclophosphamide, BCNU, and VP-16 (CBV) as a conditioning regimen for allogeneic bone marrow transplantation for patients with acute leukemia. Cancer, 1987, Mar-15, Volume: 59, Issue:6 Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Humans; Leukemia; Podophyllotoxin	1987
Clinical pharmacodynamics of continuous infusion teniposide: systemic exposure as a determinant of response in a phase I trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:7 Topics: Child; Drug Administration Schedule; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Leukemia; Lymphoma; Neuroblastoma; Podophyllotoxin; Teniposide	1987
High-dose VP-16 with intermediate-dose cytosine arabinoside in the treatment of relapsed acute nonlymphocytic leukemia. Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3 Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Leukemia; Liver; Male; Middle Aged; Podophyllotoxin; Recurrence; Time Factors	1987
[A phase II trial of etoposide (VP-16) administered intravenously in the treatment of malignant lymphoma and acute leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:11 Topics: Acute Disease; Adolescent; Adult; Aged; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Leukemia; Lymphoma; Male; Middle Aged; Podophyllotoxin	1985
[Induction of remission by sequential treatment with cytosine arabinoside (araC/high dose) and L-asparaginase]. Sangre, 1985, Volume: 30, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia; Leukemia, Lymphoid; Male; Middle Aged; Podophyllotoxin	1985
[Phase II study of NK 171 (etoposide) on malignant lymphomas and acute leukemia. A cooperative study group on NK 171 in hematological malignancies]. Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 1 Topics: Acute Disease; Adolescent; Adult; Aged; Alopecia; Anorexia; Drug Evaluation; Etoposide; Fatigue; Female; Humans; Leukemia; Lymphoma; Male; Middle Aged; Nausea; Podophyllotoxin	1986
[Etoposide (VP 16/NK 171) and cytosine arabinoside combination chemotherapy in refractory childhood leukemia]. Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1 Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia; Lymphoma; Male; Myeloproliferative Disorders; Podophyllotoxin	1986
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts. Cancer research, 1985, Volume: 45, Issue:7 Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium	1985
[Acute leukemia and various hematosarcomas. Trial treatment with a second derivative of podophyllotoxin (4-demethyl-epipodophyllotoxin beta D ethylidene glucoside VP 16213 or EPE)]. La Nouvelle presse medicale, 1974, Mar-02, Volume: 3, Issue:9 Topics: Adolescent; Adult; Aged; Agranulocytosis; Alopecia; Child; Child, Preschool; Female; Hodgkin Disease; Humans; Infant; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Podophyllotoxin; Thrombocytopenia	1974
[The influence of age and experimentally-induced disease on the tolerance of cytostatically-active materials in mice]. Arzneimittel-Forschung, 1967, Volume: 17, Issue:2 Topics: Age Factors; Aminopterin; Animals; Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Tolerance; Graft vs Host Disease; Immunosuppressive Agents; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Skin Transplantation; Thioguanine; Transplantation, Homologous	1967
[Clinical trial of chemotherapeutic combinations based on the notion of attempted cellular synchronization. Preliminary administration of an antimitotic followed by the use of cycle-dependent or phase dependent product(s)]. La Nouvelle presse medicale, 1972, Jun-24, Volume: 1, Issue:26 Topics: Amino Sugars; Anthraquinones; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Daunorubicin; DNA; Drug Combinations; Drug Tolerance; Female; Hodgkin Disease; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mitosis; Neoplasm Metastasis; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisone; Prognosis; Time Factors	1972
The stathmokinetic agents. Acta geneticae medicae et gemellologiae, 1968, Volume: 17, Issue:1 Topics: Animals; Antineoplastic Agents; Colchicine; Griseofulvin; Leukemia; Mice; Mitosis; Plants, Medicinal; Plants, Toxic; Podophyllum; Vinblastine; Vincristine	1968