Page last updated: 2024-08-21

podophyllotoxin and Leukemia P388

podophyllotoxin has been researched along with Leukemia P388 in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's11 (57.89)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chu, DT; Clement, JJ; Klein, LL; McDonald, EJ; Plattner, JJ; Yeung, CM1
Jurd, L; Narayanan, VL; Paull, KD1
Chai, H; Cruz, JG; Hernández, L; Mar, W; Novelo, M; Pereda-Miranda, R; Pezzuto, JM1
Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS1
Daley, L; Demerseman, P; Etiévant, C; Guminski, Y; Hill, BT; Imbert, T; Kruczynski, A; Monneret, C1
Baasner, S; Böhm, KJ; Gerlach, M; Günther, EG; Müller, K; Prinz, H; Schmidt, P; Unger, E; Zuse, A1
Arimondo, PB; Bertounesque, E; Dauzonne, D; Duca, M; Guianvarc'h, D; Kraus-Berthier, L; Léonce, S; Meresse, P; Monneret, C; Pfeiffer, B; Pierré, A; Renard, P; Thirot, S1
Hall, IH; Lee, KH; Levy, RK1
Alberts, DS; Dorr, RT1
Fujimoto, K; Kobunai, T; Nomura, M; Shibata, J; Sugimoto, Y; Terada, T; Wierzba, K; Yamada, Y; Yamashita, J; Yamazaki, R1
Anyanwutaku, IO; Chen, HX; Cheng, YC; Guo, X; Ji, Z; Lee, KH1
Choe, YH; Conover, CD; Greenwald, RB; Guan, S; Martinez, A; Pendri, A; Shum, KL; Wu, D; Yao, Z1
Chen, YZ; Pan, JL; Wang, YG1
Fujimoto, K; Kobunai, T; Nomura, M; Takeda, S; Terada, T; Wierzba, K; Yamada, Y; Yamaguchi, H; Yamashita, J1
Bugat, R; Canal, P; Chatelut, E; Chevreau, C; de Forni, M; Houin, G; Johnson, NP; Plusquellec, Y; Roche, H1
Iwabuchi, M; Takahashi, K1
Murray, SL; Slater, LM; Stupecky, M; Sweet, P; Wetzel, MW1
Inaba, M1
Fairchild, C; Gottlieb, HE; Nudelman, A; Ruse, M1

Trials

1 trial(s) available for podophyllotoxin and Leukemia P388

ArticleYear
Teniposide and cisplatin given by intraperitoneal administration: preclinical and phase I/pharmacokinetic studies.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:3

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Injections, Intraperitoneal; Leukemia P388; Leukopenia; Male; Mice; Middle Aged; Peritoneal Neoplasms; Podophyllotoxin; Remission Induction; Teniposide

1991

Other Studies

18 other study(ies) available for podophyllotoxin and Leukemia P388

ArticleYear
Synthesis and antitumor activity of structural analogues of the epipodophyllotoxins.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Etoposide; Humans; Indans; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured

1991
In vivo antitumor activity of 6-benzyl-1,3-benzodioxole derivatives against the P388, L1210, B16, and M5076 murine models.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Bucladesine; Cell Differentiation; Dioxoles; DNA Topoisomerases, Type I; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Tubulin

1987
Cytotoxic constituents from Hyptis verticillata.
    Journal of natural products, 1993, Volume: 56, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Artemia; Candida albicans; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Mexico; Mice; Microbial Sensitivity Tests; Plants, Medicinal; Podophyllotoxin; Rats

1993
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.
    Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9

    Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

1993
Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.
    Journal of medicinal chemistry, 1998, Nov-05, Volume: 41, Issue:23

    Topics: Animals; Antineoplastic Agents; Biopolymers; Drug Screening Assays, Antitumor; Female; Glycosides; Glycosylation; Humans; Inhibitory Concentration 50; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured

1998
9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Proliferation; Cell Survival; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia P388; Mice; Molecular Structure; Structure-Activity Relationship; Thiophenes; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

2006
Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Animals; Antineoplastic Agents; Carbamates; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia P388; Mice; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transplantation, Heterologous

2005
Antitumor agents LXII: synthesis and biological evaluation of podophyllotoxin esters and related derivatives.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:10

    Topics: Animals; Leukemia P388; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Structure-Activity Relationship

1983
Skin ulceration potential without therapeutic anticancer activity for epipodophyllotoxin commercial diluents.
    Investigational new drugs, 1983, Volume: 1, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Etoposide; Humans; Leukemia P388; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Podophyllotoxin; Skin Ulcer; Solvents; Teniposide; Tumor Stem Cell Assay

1983
Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents.
    Journal of medicinal chemistry, 1993, Jun-11, Volume: 36, Issue:12

    Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin Modulators; Tumor Cells, Cultured

1993
Activities of novel nonglycosidic epipodophyllotoxins in etoposide-sensitive and -resistant variants of human KB cells, P-388 cells, and in vivo multidrug-resistant murine leukemia cells.
    Molecular pharmacology, 1996, Volume: 49, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Damage; Drug Resistance, Multiple; Etoposide; Female; Humans; KB Cells; Leukemia P388; Leukemia, Experimental; Mice; Podophyllotoxin; Topoisomerase II Inhibitors

1996
Drug delivery of anticancer agents: water soluble 4-poly (ethylene glycol) derivatives of the lignan, podophyllotoxin.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Sep-20, Volume: 61, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Leukemia P388; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Nuclear Magnetic Resonance, Biomolecular; Podophyllotoxin; Polyethylene Glycols; Solubility; Transplantation, Heterologous; Tumor Cells, Cultured; Water

1999
[Synthesis of epipodophyllotoxin carboxylates and antitumor activity in vitro].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Humans; Leukemia P388; Liver Neoplasms; Mice; Molecular Structure; Podophyllotoxin; Stomach Neoplasms; Tumor Cells, Cultured

1997
Antitumor agents. I. DNA topoisomerase II inhibitory activity and the structural relationship of podophyllotoxin derivatives as antitumor agents.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:10

    Topics: Animals; Antineoplastic Agents; Leukemia P388; Mice; Podophyllotoxin; Sarcoma, Experimental; Structure-Activity Relationship; Topoisomerase II Inhibitors

1992
[Kinetics of etoposide cytotoxicity against mouse P388 leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Animals; Bleomycin; Cell Cycle; Cell Survival; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Leukemia P388; Leukemia, Experimental; Melphalan; Mice; Peplomycin; Podophyllotoxin; Tumor Stem Cell Assay; Vinblastine

1985
Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance.
    Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Etoposide; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Podophyllotoxin; Verapamil; Vincristine

1986
[Studies on the mechanism of multidrug resistance].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Doxorubicin; Drug Resistance; Leukemia P388; Leukemia, Experimental; Mice; Naphthacenes; Podophyllotoxin; Quinacrine; Vinca Alkaloids; Vincristine

1987
Studies in sugar chemistry. VII. Glucuronides of podophyllum derivatives.
    Archiv der Pharmazie, 1997, Volume: 330, Issue:9-10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Drug Screening Assays, Antitumor; Glucuronates; Humans; Leukemia P388; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Plants, Medicinal; Plants, Toxic; Podophyllum; Tumor Cells, Cultured

1997