Page last updated: 2024-08-21

podophyllotoxin and Leukemia L 1210

podophyllotoxin has been researched along with Leukemia L 1210 in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (70.69)	18.7374
1990's	12 (20.69)	18.2507
2000's	5 (8.62)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Jurd, L; Narayanan, VL; Paull, KD	1
Chang, JJ; Hamel, E; Juang, JP; Kuo, SC; Lednicer, D; Lee, HZ; Lin, CM; Lin, YT; Paull, KD; Wu, TS	1
Daley, L; Demerseman, P; Etiévant, C; Guminski, Y; Hill, BT; Imbert, T; Kruczynski, A; Monneret, C	1
Annereau, JP; Bailly, C; Barret, JM; Brel, V; Delcros, JG; Guilbaud, N; Guminski, Y; Imbert, T; Kruczynski, A; Lansiaux, A; Vispé, S	1
Arimondo, P; Bertounesque, E; Magiatis, P; Monneret, C; Roulland, E	1
Chen, XH; He, Y; Ma, WY; Zhang, CN	1
Arimondo, PB; Dauzonne, D; Duca, M; Léonce, S; Monneret, C; Pfeiffer, B; Pierré, A	1
Glisson, B; Liu, L; Ross, W; Rowe, T; Yalowich, J	1
Glisson, BS; Hande, KR; Ross, WE; Wozniak, AJ	1
Glisson, BS; Ross, WE; Smallwood, SE	1
Lee, T; Roberts, D	2
Ross, WE; Yalowich, JC	2
Ross, WE; Wozniak, AJ	1
Jardine, I; Kozlowski, J; Strife, RJ	1
Hilliard, S; Karas, JG; Peck, C; Roberts, D	1
Hacker, M; Jackson, CW; Roberts, D	1
Hilliard, S; Peck, C; Roberts, D	1
Chen, XH; Ma, WY; Wang, TD; Wang, ZG; Yin, SF; Zhang, CN	1
Chen, XH; Ma, WY; Wang, TD; Wang, ZG; Yin, SF; Zhang, CN; Zhuang, W	1
Chen, XH; Ma, WY; Wang, TD; Yin, SF; Zhang, CN	1
Li, BS; Ma, WY; Wang, ZG; Yin, SF; Zhang, CN	1
Fujimoto, K; Kobunai, T; Nomura, M; Shibata, J; Sugimoto, Y; Terada, T; Wierzba, K; Yamada, Y; Yamashita, J; Yamazaki, R	1
Jia, ZP; Wang, R; Xie, JW; Xu, LT	1
Couture, A; Deniau, E; Grandclaudon, P; Lebrun, S; Léonce, S; Pfeiffer, B; Renard, P	1
Chen, Y; Lu, K	1
Allen, LM	1
Coulter, D; Kalish, R; Valeriote, FA; Vietti, TJ	1
Allen, L	1
Hacker, M; Roberts, D	1
Dombernowsky, P; Nissen, NI	2
Stähelin, H	2
Avery, T; Rivera, G; Roberts, DW	1
Li, BS; Ma, WY; Wang, ZG; Zhang, CN	1
Lee, BS; Ma, WY; Wang, ZG; Yin, SF; Zhang, CN; Zhuang, W	1
Gorin, NC	1
Beerman, TA; Sigmund, RD; Woynarowski, JM	2
Foglesong, PD; Parganas, E; Roberts, DW; Wiggins, L	1
Ellis, AL; Gewirtz, DA; Povirk, LF; Randolph, JK; Swerdlow, PS; Yalowich, JC; Yanovich, S	1
Kupfer, G; Ross, W; Rowe, T	1
Glisson, BS; Hodges, PK; Ross, WE; Smallwood-Kentro, S; Sullivan, DM	1
Dorr, RT; Gerner, EW; Liddil, JD	1
Kerrigan, D; Kohn, KW; Pommier, Y	1
Chu, PS; Dempcy, RO; Hamel, E; Lin, CM; Pettit, GR; Schmidt, JM; Singh, SB	1
Murray, SL; Slater, LM; Stupecky, M; Sweet, P; Wetzel, MW	1
Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sasada, M; Sawada, H; Tashima, M; Uchino, H	1
Ashmun, R; Lee, T; Parganas, E; Roberts, D; Wiggins, L; Yalowich, J	1
Kondo, S; Nishimura, Y; Saito, H; Takeuchi, T; Umezawa, H; Yoshikawa, H	2
Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H; Usui, T	1
Kuramochi, H; Nagamine, S; Nishikawa, K; Okamoto, K; Takahashi, K	1
Herrmann, R; Osswald, H; Youssef, M	1
Avery, TL; Price, RA; Roberts, D	1

Trials

1 trial(s) available for podophyllotoxin and Leukemia L 1210

Article	Year
VP-16: phase specific cytocidal activity and preliminary trials in acute monocytic leukemias. Nihon Gan Chiryo Gakkai shi, 1986, Apr-20, Volume: 21, Issue:3 Topics: Animals; Cell Cycle; Clinical Trials as Topic; DNA, Neoplasm; Humans; Interphase; Leukemia L1210; Leukemia, Monocytic, Acute; Male; Mice; Middle Aged; Podophyllotoxin	1986

Other Studies

57 other study(ies) available for podophyllotoxin and Leukemia L 1210

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
In vivo antitumor activity of 6-benzyl-1,3-benzodioxole derivatives against the P388, L1210, B16, and M5076 murine models. Journal of medicinal chemistry, 1987, Volume: 30, Issue:10 Topics: Animals; Antineoplastic Agents; Astrocytoma; Bucladesine; Cell Differentiation; Dioxoles; DNA Topoisomerases, Type I; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Tubulin	1987
Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. Journal of medicinal chemistry, 1993, Apr-30, Volume: 36, Issue:9 Topics: Animals; Antineoplastic Agents; Humans; Intestinal Neoplasms; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nasopharyngeal Neoplasms; Quinolines; Quinolones; Software; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	1993
Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611. Journal of medicinal chemistry, 1998, Nov-05, Volume: 41, Issue:23 Topics: Animals; Antineoplastic Agents; Biopolymers; Drug Screening Assays, Antitumor; Female; Glycosides; Glycosylation; Humans; Inhibitory Concentration 50; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transplantation, Heterologous; Tubulin; Tumor Cells, Cultured	1998
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system. Cancer research, 2008, Dec-01, Volume: 68, Issue:23 Topics: Animals; Binding, Competitive; Biogenic Polyamines; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Delivery Systems; Etoposide; Female; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays	2008
Hemi-synthesis and biological activity of new analogues of podophyllotoxin. Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:11 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Enzyme Inhibitors; Humans; Leukemia L1210; Necrosis; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship; Swine; Topoisomerase I Inhibitors; Tubulin	2002
[Synthesis and activities of 4-deoxy-4 beta-arylmehtylene sulfonylamido-4'-demethylpodophyllotoxins]. Yao xue xue bao = Acta pharmaceutica Sinica, 2001, Volume: 36, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; KB Cells; Leukemia L1210; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Tumor Cells, Cultured	2001
Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation. Organic & biomolecular chemistry, 2005, Mar-21, Volume: 3, Issue:6 Topics: Animals; Antineoplastic Agents; Carbamates; Cell Division; DNA; DNA Damage; Enzyme Inhibitors; Etoposide; G2 Phase; Leukemia L1210; Mice; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors	2005
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage. Cancer research, 1984, Volume: 44, Issue:12 Pt 1 Topics: Animals; Cattle; Cell Nucleus; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Structure-Activity Relationship; Teniposide; Thymus Gland	1984
Inhibition of etoposide-induced DNA damage and cytotoxicity in L1210 cells by dehydrogenase inhibitors and other agents. Cancer research, 1984, Volume: 44, Issue:2 Topics: Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Benzoates; Benzoic Acid; Cell Survival; Disulfiram; Ditiocarb; DNA; Etoposide; Leukemia L1210; Mice; NADP; Podophyllotoxin; Thiocarbamates	1984
Characterization of VP-16-induced DNA damage in isolated nuclei from L1210 cells. Biochimica et biophysica acta, 1984, Oct-05, Volume: 783, Issue:1 Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; DNA; Etoposide; Hydrogen-Ion Concentration; Leukemia L1210; Magnesium; Mice; Nucleotides; Podophyllotoxin; Temperature	1984
Flux of teniposide (VM-26) across the plasma membrane of teniposide-resistant sublines of L1210 cells. Cancer research, 1984, Volume: 44, Issue:7 Topics: Animals; Biological Transport; Cell Membrane; Drug Resistance; Kinetics; Leukemia L1210; Mice; Mutation; Podophyllotoxin; Teniposide	1984
Selection and characterization of L1210 sublines resistant to teniposide (VM-26). Cancer research, 1984, Volume: 44, Issue:7 Topics: Animals; Cell Division; Chromosome Banding; Clone Cells; Drug Resistance; Karyotyping; Kinetics; Leukemia L1210; Metaphase; Mice; Mutation; Podophyllotoxin; Teniposide	1984
Potentiation of etoposide-induced DNA damage by calcium antagonists in L1210 cells in vitro. Cancer research, 1984, Volume: 44, Issue:8 Topics: Animals; Cell Division; Cell Nucleus; Cell Survival; DNA Replication; DNA, Neoplasm; Drug Synergism; Etoposide; Gallopamil; Kinetics; Leukemia L1210; Mice; Podophyllotoxin; Verapamil	1984
DNA damage as a basis for 4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene-beta-D-glucopyranoside) (etoposide) cytotoxicity. Cancer research, 1983, Volume: 43, Issue:1 Topics: Animals; Chemical Phenomena; Chemistry; Colony-Forming Units Assay; DNA; DNA, Single-Stranded; Dose-Response Relationship, Drug; Etoposide; Leukemia L1210; Mice; Podophyllotoxin	1983
Synthesis, 470-MHz 1H NMR spectra, and activity of delactonized derivatives of the anticancer drug etoposide. Journal of medicinal chemistry, 1982, Volume: 25, Issue:9 Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Etoposide; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Podophyllotoxin	1982
Response of L1210 leukemia to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea plus 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside). Cancer research, 1981, Volume: 41, Issue:10 Topics: Animals; Carmustine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Mice; Mice, Inbred Strains; Podophyllotoxin; Prognosis	1981
Effect of VM-26 on the haematological responses of mice to L1210 leukaemia. British journal of cancer, 1980, Volume: 42, Issue:5 Topics: Animals; Female; Hematocrit; Leukemia L1210; Leukocyte Count; Mice; Neoplasm Transplantation; Platelet Count; Podophyllotoxin; Teniposide; Transplantation, Homologous	1980
Sedimentation of DNA from L1210 cells after treatment with 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) or 1-beta-D-arabinofuranosylcytosine or both drugs. Cancer research, 1980, Volume: 40, Issue:11 Topics: Animals; Antibiotics, Antineoplastic; Centrifugation, Density Gradient; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Leukemia L1210; Mice; Podophyllotoxin; Teniposide; Time Factors	1980
[Synthesis and antitumor activity of 4-O-(halogenated) acyl-4'-demethylepipodophyllotoxin analogues]. Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:10 Topics: Animals; Etoposide; Humans; KB Cells; Leukemia L1210; Mice; Podophyllotoxin; Tumor Cells, Cultured	1993
[Synthesis and antitumor activity of 4-S-(5-amido-1,3,4-thiodiazol-2-yl)4-deoxy-4'-demethylepipodophyllotoxi n analogues]. Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:10 Topics: Animals; Etoposide; Humans; KB Cells; Leukemia L1210; Podophyllotoxin; Tumor Cells, Cultured	1993
[Synthesis and antitumor activity of 4-(2-amido-2-ethoxycarbonyl) ethylsulfenyl-4-deoxy-4'-demethylepipodophyllotoxin analogues]. Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:9 Topics: Animals; Antineoplastic Agents; Humans; KB Cells; Leukemia L1210; Podophyllotoxin; Tumor Cells, Cultured	1993
[Synthesis and antitumor activities of 4-acylamido-4-deoxy-4'-demethylepipodophyllotoxin analogues]. Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; Leukemia L1210; Molecular Structure; Podophyllotoxin; Tumor Cells, Cultured	1993
Antitumor agents. 3. Synthesis and biological activity of 4 beta-alkyl derivatives containing hydroxy, amino, and amido groups of 4'-O-demethyl-4-desoxypodophyllotoxin as antitumor agents. Journal of medicinal chemistry, 1993, Jun-11, Volume: 36, Issue:12 Topics: Animals; Antineoplastic Agents; Etoposide; Humans; Leukemia L1210; Leukemia P388; Lung Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin Modulators; Tumor Cells, Cultured	1993
Action of free radical in podophyllic acid piperindyl hydrazone nitroxide radical on its antitumor activity and toxicity. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:6 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; DNA, Neoplasm; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mitotic Index; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Stomach Neoplasms; Tumor Cells, Cultured	1999
First synthesis and pharmacological evaluation of benzoindolizidine and benzoquinolizidine analogues of alpha- and beta-peltatin. Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:8 Topics: Animals; Antineoplastic Agents; Cell Cycle; DNA; Drug Screening Assays, Antitumor; Indolizines; Leukemia L1210; Mice; Molecular Structure; Podophyllotoxin; Quinolizines	2000
[Synthesis of spin labeled analogue of podophyllotoxin glycoside]. Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:12 Topics: Animals; Antineoplastic Agents, Phytogenic; Leukemia L1210; Mice; Podophyllotoxin; Spin Labels; Tumor Cells, Cultured	1998
Comparison of uptake and binding of two epipodophyllotoxin glucopyranosides, 4'-demethyl epipodophyllotoxin thenylidene-beta-D-glucoside and 4'-demethyl epipodophyllotoxin ethylidene-beta-D-glucoside, in the L1210 leukemia cell. Cancer research, 1978, Volume: 38, Issue:8 Topics: Animals; Binding Sites; Biological Transport; Cell Nucleus; Etoposide; Kinetics; Leukemia L1210; Mice; Mice, Inbred DBA; Podophyllotoxin; Teniposide; Thermodynamics; Vinblastine	1978
Kinetics of cytotoxicity of VM-26 and VP-16-213 on L1210 leukemia and hematopoietic stem cells. Cancer treatment reports, 1978, Volume: 62, Issue:9 Topics: Animals; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Etoposide; Hematopoietic Stem Cells; Leukemia L1210; Podophyllotoxin; Rats; Teniposide; Time Factors	1978
The role of drug disposition kinetics on cellular transport of the antineoplastic agent VM-26. Drug metabolism reviews, 1978, Volume: 8, Issue:1 Topics: Animals; Biological Transport, Active; Chemical Phenomena; Chemistry; Diffusion; Etoposide; Kinetics; Leukemia L1210; Mice; Models, Biological; Podophyllotoxin; Protein Binding; Serum Albumin; Teniposide	1978
VM26-induced changes in hepatic intermediary metabolism of mice. Cancer research, 1977, Volume: 37, Issue:9 Topics: Animals; Blood Glucose; Doxorubicin; Drug Synergism; Female; Glucose; Hexosephosphates; In Vitro Techniques; Isocitrates; Ketoglutaric Acids; Leukemia L1210; Liver; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria, Liver; Oxygen Consumption; Podophyllotoxin; Succinates; Teniposide	1977
Combination chemotherapy with 4'Demethylepipodophyllotoxin 9-(4,6-0-ethylidene-beta-D-glucopyranoside), VP 16-213 (NSC 141540) in L1210 leukemia. European journal of cancer, 1976, Volume: 12, Issue:3 Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Podophyllotoxin; Vincristine	1976
Delayed toxicity of epipodophyllotoxin derivatives (VM 26 and VP 16-213), due to a local effect. European journal of cancer, 1976, Volume: 12, Issue:11 Topics: Animals; Dose-Response Relationship, Drug; Etoposide; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Liver; Lung; Male; Mice; Organ Size; Podophyllotoxin; Rats; Teniposide; Time Factors	1976
Response of L1210 to combinations of cytosine arabinoside and VM-26 or VP16-213. European journal of cancer, 1975, Volume: 11, Issue:9 Topics: Animals; Cytarabine; Drug Therapy, Combination; Etoposide; Female; Leukemia L1210; Leukemia, Experimental; Mice; Podophyllotoxin; Pyrans; Teniposide	1975
[Synthesis and antitumor activity of 4-alkylthio-4-deoxy-4'-demethylepipodophyllotxin derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:9 Topics: Animals; Antineoplastic Agents; Humans; KB Cells; Leukemia L1210; Podophyllotoxin; Tumor Cells, Cultured	1992
[Synthesis and antitumor activities of 4-acylthiol-4-deoxy-4'-demethylepipodophyllotoxin analogues]. Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:5 Topics: Animals; Antineoplastic Agents; Leukemia L1210; Podophyllotoxin	1992
Pharmacological purging of bone marrow with drugs other than cyclophosphamide derivatives. Revue francaise de transfusion et immuno-hematologie, 1985, Volume: 28, Issue:5 Topics: Animals; Antineoplastic Agents; Bleomycin; Bone Marrow; Cell Line; Cell Separation; Etoposide; Hematopoietic Stem Cells; Leukemia L1210; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Podophyllotoxin	1985
DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells. Biochemistry, 1989, May-02, Volume: 28, Issue:9 Topics: Amsacrine; Animals; Bisbenzimidazole; Cell Nucleus; Deoxyribonucleoproteins; Distamycins; DNA Damage; DNA, Neoplasm; Indoles; Kinetics; Leukemia L1210; Mice; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors	1989
Reduced formation of lesions in the DNA of a multidrug-resistant L1210 subline selected for teniposide resistance. Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:3 Topics: Animals; DNA; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Leukemia L1210; Podophyllotoxin; Potassium Cyanide; Teniposide; Tumor Cells, Cultured; Verapamil	1989
Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization. Cancer communications, 1989, Volume: 1, Issue:3 Topics: Animals; Cell Line; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Endopeptidase K; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Liver Neoplasms, Experimental; Mice; Mitoxantrone; Podophyllotoxin; Protein Binding; Rats; Serine Endopeptidases; Teniposide; Tumor Cells, Cultured	1989
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA. Biochimica et biophysica acta, 1988, May-06, Volume: 950, Issue:1 Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors	1988
Inhibition of epipodophyllotoxin cytotoxicity by interference with topoisomerase-mediated DNA cleavage. Biochemical pharmacology, 1985, Jul-15, Volume: 34, Issue:14 Topics: Animals; Cell Survival; DNA; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Ethidium; Etoposide; Leukemia L1210; Mice; Podophyllotoxin	1985
Proliferation dependence of topoisomerase II mediated drug action. Biochemistry, 1986, Apr-22, Volume: 25, Issue:8 Topics: Aminoacridines; Amsacrine; Animals; Cell Line; Cricetinae; Cricetulus; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Female; HeLa Cells; Humans; Intercalating Agents; Kinetics; Leukemia L1210; Mice; Ovary; Plasmids; Podophyllotoxin	1986
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines. Cancer research, 1986, Volume: 46, Issue:8 Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Eflornithine; Etoposide; Humans; Leukemia L1210; Mice; Multiple Myeloma; Nucleic Acid Conformation; Ornithine; Podophyllotoxin; Polyamines; Putrescine	1986
Protein-linked DNA strand breaks produced by etoposide and teniposide in mouse L1210 and human VA-13 and HT-29 cell lines: relationship to cytotoxicity. NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4 Topics: Animals; Cell Line; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Humans; Kinetics; Leukemia L1210; Podophyllotoxin; Teniposide	1987
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. Molecular pharmacology, 1988, Volume: 34, Issue:2 Topics: Animals; Anisoles; Antineoplastic Agents; Bibenzyls; Binding Sites; Binding, Competitive; Colchicine; Leukemia L1210; Mice; Mitosis; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Tubulin	1988
Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance. Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Etoposide; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Podophyllotoxin; Verapamil; Vincristine	1986
Expressions of resistance and cross-resistance in teniposide-resistant L1210 cells. Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cyanides; Drug Resistance; Leukemia L1210; Lipid Metabolism; Mice; Neoplasm Proteins; Phenotype; Podophyllotoxin; Teniposide; Verapamil	1987
Studies on lignan lactone antitumor agents. I. Synthesis of aminoglycosidic lignan variants related to podophyllotoxin. Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:9 Topics: Animals; Antineoplastic Agents, Phytogenic; Etoposide; Leukemia L1210; Mice; Podophyllotoxin	1986
Studies on lignan lactone antitumor agents. II. Synthesis of N-alkylamino- and 2,6-dideoxy-2-aminoglycoside lignan variants related to podophyllotoxin. Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:9 Topics: Aminoglycosides; Animals; Antineoplastic Agents, Phytogenic; Etoposide; Leukemia L1210; Mice; Podophyllotoxin	1986
Effects of VP-16 on cell growth and metabolism of nucleic acids in mouse leukemia L-1210 cells and on the activity of DNA polymerase I of E. coli. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1985, Volume: 48, Issue:6 Topics: Animals; Cell Nucleus; Cytoplasm; Dimethyl Sulfoxide; DNA; DNA Polymerase I; Escherichia coli; Leukemia L1210; Mice; Podophyllotoxin	1985
Verapamil-induced augmentation of etoposide accumulation in L1210 cells in vitro. Cancer research, 1985, Volume: 45, Issue:4 Topics: Animals; Cells, Cultured; DNA Repair; Drug Synergism; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Tritium; Verapamil	1985
[Antitumor effect of etoposide and its analogs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11 Topics: Animals; Cell Division; Dogs; Etoposide; HeLa Cells; Humans; Leukemia L1210; Male; Mice; Podophyllotoxin; Structure-Activity Relationship	1985
Timing- and sequence-dependent synergism between etoposide and methotrexate or etoposide, methotrexate and 5-fluorouracil in advanced leukemia L1210. Cancer letters, 1985, Volume: 29, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Etoposide; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Podophyllotoxin; Time Factors	1985
Delayed toxicity of 4'-demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) (NSC-122819; VM-26) in mice. Cancer chemotherapy reports, 1973, Volume: 57, Issue:2 Topics: Animals; Body Weight; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Glycosides; Leukemia L1210; Leukemia, Experimental; Liver; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasm Transplantation; Organ Size; Pancreas; Podophyllotoxin; Time Factors; Transplantation, Homologous	1973
Schedule dependency of the antileukemic activity of the podophyllotoxin-derivative VP 16-213 (NSC-141540) in L1210 leukemia. Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1973, Volume: 81, Issue:5 Topics: Animals; Drug Evaluation, Preclinical; Female; Injections, Intraperitoneal; Leukemia L1210; Male; Mice; Neoplasm Transplantation; Podophyllotoxin; Time Factors; Transplantation, Homologous	1973
4'-Demethyl-epipodophyllotoxin thenylidene glucoside (VM 26), a podophyllum compound with a new mechanism of action. European journal of cancer, 1970, Volume: 6, Issue:4 Topics: Animals; Carcinoma 256, Walker; Culture Techniques; Female; Fibroblasts; Leukemia L1210; Male; Mast-Cell Sarcoma; Mice; Mitosis; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Rats	1970