podophyllotoxin has been researched along with Hepatocellular Carcinoma in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (41.67) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Boykin, DW; Hu, L; Jiang, JD; Li, Y; Li, ZR; Ling, YH; Qu, J | 1 |
| Chen, Y; Liu, L; Nie, X; Shi, D; Wang, J; Wang, Y; Wei, G; Zhang, L; Zheng, C | 1 |
| Cong, Y; Li, HM; Liu, X; Tang, PY; Tang, YJ; Zhang, SY; Zhao, W | 1 |
| Dong, Z; Gu, X; Qiu, L; Shi, Y; Wang, L; Wu, W; Yan, X; Yao, D; Yao, M; Yao, N | 1 |
| Chen, J; Dong, ZZ; Wang, L; Yan, MJ; Yan, XD; Yao, DF; Yao, M; Yao, NH | 1 |
| Chen, L; E, C; Li, J; Pan, Y; Shao, D; Zhang, D; Zhang, X | 1 |
| Chang, TS; Chen, CL; Huang, YH; Kuo, LM; Kuo, YC; Lee, KF; Lin, SE; Lin, SY; Liu, JJ; Tsai, YH; Tung, SY; Wu, YC | 1 |
| Bissinger, M; Breuhahn, K; Ehemann, V; Gretz, N; Khamidjanov, A; Nussbaum, T; Ryschich, E; Samarin, J; Schirmacher, P; Yu, X | 1 |
| KANO, K; MAKINO, S; SASAKI, M; TANAKA, T | 1 |
| Ni, JM; Qiao, H; Zhang, XY | 1 |
| An, L; Han, Y; Miao, R; Wang, Q; Yang, J | 1 |
| Brunner, KW; Cavalli, F; Goldhirsch, A; Joss, R; Ryssel, HJ; Sonntag, RW | 1 |
| Cavalli, F; Goldhirsch, A; Hansen, HH; Renard, J; Rozencweig, M | 1 |
| Jungi, WF | 1 |
| Johnson, PJ; Melia, WM; Williams, R | 1 |
| Wen, YJ | 1 |
| Chiang, JY; Foti, D; Stroup, D | 1 |
| Chen, YZ; Pan, JL; Wang, YG | 1 |
| Brunner, KW; Cavalli, F; Sonntag, RW | 1 |
| Brunner, KW; Cavalli, F; Gerber, A; Ryssel, HJ; Sonntag, RW; Tschopp, L | 1 |
| Fukuoka, M; Hirano, M; Honma, T; Hoshino, A; Meguro, S; Nakamura, T; Ogawa, M; Shirakawa, S; Toki, H; Yoshida, S | 1 |
| Kimura, K; Niitani, H; Yamada, K | 1 |
| Bezwoda, WR; Derman, DP; Kew, M; Weaving, A | 1 |
| Chen, H; Li, L; Li, Q; Wang, H; Wang, Z; Zhang, M | 1 |
1 review(s) available for podophyllotoxin and Hepatocellular Carcinoma
| Article | Year |
|---|---|
[Etoposide. A new highly effective cytostatic agent in anaplastic small-cell bronchial carcinoma, other solid tumors and hemoblastoses].
Topics: Bronchial Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Small Cell; Cell Division; Choriocarcinoma; Etoposide; Female; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Male; Ovarian Neoplasms; Podophyllotoxin; Pregnancy; Testicular Neoplasms; Uterine Neoplasms | 1981 |
3 trial(s) available for podophyllotoxin and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Induction of remission in hepatocellular carcinoma. A comparison of VP 16 with adriamycin.
Topics: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; Doxorubicin; Etoposide; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Podophyllotoxin; Prognosis; Random Allocation | 1983 |
[Phase I clinical study of NK 171 (etoposide)].
Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Podophyllotoxin | 1985 |
Combination chemotherapy of hepatocellular cancer. Comparison of adriamycin + VM 26 + 5-fluorouracil with mAMSA + VM 26 + 5-fluorouracil.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Podophyllotoxin; Random Allocation; Teniposide; Time Factors | 1987 |
20 other study(ies) available for podophyllotoxin and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors.
Topics: Animals; Antimitotic Agents; Apoptosis; Breast Neoplasms; Carbazoles; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Sulfonamides; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2006 |
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship | 2017 |
Conjugating 4β-NH-(5-Aminoindazole)-podophyllotoxin and Galectin-1-Targeted Aptamer for Synergistic Chemo-Immunotherapy of Hepatocellular Carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Galectin 1; Humans; Immunotherapy; Liver Neoplasms; Mice; Podophyllotoxin; Tumor Microenvironment | 2023 |
Abnormal expression of insulin-like growth factor-I receptor in hepatoma tissue and its inhibition to promote apoptosis of tumor cells.
Topics: Adult; Aged; Apoptosis; Base Sequence; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Female; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Podophyllotoxin; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2013 |
[Effects of inhibited IGF-IR expression on proliferation and apoptosis of human hepatocellular carcinoma cell lines].
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; Liver Neoplasms; Podophyllotoxin; Receptor, IGF Type 1 | 2013 |
The insulin-like growth factor-I receptor inhibitor picropodophyllin-induced selective apoptosis of hepatocellular carcinoma cell through a caspase-dependent mitochondrial pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Liver Neoplasms; Mitochondria, Liver; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptor, IGF Type 1 | 2013 |
Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Cell Survival; Chemokine CCL2; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Homeodomain Proteins; Humans; Inflammation; Insulin-Like Growth Factor I; Liver Neoplasms; Nanog Homeobox Protein; Neoplastic Stem Cells; Octamer Transcription Factor-3; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Spheroids, Cellular; Tumor Cells, Cultured | 2016 |
Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis.
Topics: Animals; Autocrine Communication; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor II; Liver Neoplasms; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Podophyllotoxin; Protein Kinase Inhibitors; Receptor, IGF Type 1; Signal Transduction; Transplantation, Heterologous; Tumor Cells, Cultured; Up-Regulation | 2008 |
The cytological effect of chemicals on tumors. XV. Inhibitory effects of podophyllin (or podophyllotoxin) and triethylene melamine, alone and in combination, on ascites tumors of rats.
Topics: Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Liver Neoplasms; Podophyllin; Podophyllotoxin; Podophyllum; Rats; Sarcoma; Sarcoma, Experimental; Sarcoma, Yoshida; Triethylenemelamine | 1963 |
[Studies on antitumor effects of podophyllotoxin nanoliposome].
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Liposomes; Liver Neoplasms; Mice; Nanostructures; Neoplasm Transplantation; Podophyllotoxin; Random Allocation | 2006 |
Seleno-podophyllotoxin derivatives induce hepatoma SMMC-7721 cell apoptosis through Bax pathway.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Shape; Cytochromes c; Etoposide; Humans; Liver Neoplasms; Membrane Potentials; Mitochondria; Molecular Structure; Podophyllotoxin | 2008 |
Phase II study of oral VP-16-213 in hepatocellular carcinoma.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Drug Evaluation; Etoposide; Humans; Liver Neoplasms; Middle Aged; Podophyllotoxin | 1981 |
Etoposide single-agent chemotherapy for solid tumors.
Topics: Carcinoma, Hepatocellular; Etoposide; Female; Head and Neck Neoplasms; Humans; Liver Neoplasms; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Sarcoma; Soft Tissue Neoplasms | 1982 |
[Application of crossed assay design in test of drug sensitivity in vitro in combined chemotherapy of liver cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Mitomycin; Podophyllotoxin; Tumor Cells, Cultured | 1993 |
Basic transcription element binding protein (BTEB) transactivates the cholesterol 7 alpha-hydroxylase gene (CYP7A).
Topics: Animals; Bile Acids and Salts; Binding Sites; Carcinoma, Hepatocellular; Cholesterol 7-alpha-Hydroxylase; DNA-Binding Proteins; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gene Expression Regulation; Humans; Kruppel-Like Transcription Factors; Liver; Podophyllin; Podophyllotoxin; Promoter Regions, Genetic; Protein Binding; Rats; Transcription Factors; Tumor Cells, Cultured | 1998 |
[Synthesis of epipodophyllotoxin carboxylates and antitumor activity in vitro].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Humans; Leukemia P388; Liver Neoplasms; Mice; Molecular Structure; Podophyllotoxin; Stomach Neoplasms; Tumor Cells, Cultured | 1997 |
Epipodophyllin derivative (VP 16-213) in treatment of solid tumours.
Topics: Carcinoma, Hepatocellular; Etoposide; Humans; Liver Neoplasms; Podophyllotoxin; Teratoma | 1977 |
[Therapeutic results using VP 16-213 alone or in combination with 5-fluorouracil in liver cancer (hepatoma)].
Topics: Adult; Aged; Carcinoma, Hepatocellular; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Podophyllotoxin | 1977 |
[Phase II study of VP-16 (capsule) in solid tumors. A cooperative study].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Capsules; Carcinoma, Hepatocellular; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukopenia; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nausea; Podophyllotoxin; Soft Tissue Neoplasms; Thrombocytopenia | 1985 |
The Effect of p53-R249S on the Suppression of Hepatocellular Carcinoma Cells Survival Induced by Podophyllum Derivatives.
Topics: Antineoplastic Agents, Phytogenic; Biological Products; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Molecular Docking Simulation; Molecular Structure; Podophyllum; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2020 |