podophyllotoxin has been researched along with Disease Models, Animal in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.14) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 7 (20.00) | 29.6817 |
| 2010's | 19 (54.29) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA | 1 |
| Bakunov, SA; Bakunova, SM; Brun, R; Ghebru, M; Tidwell, RR; Wenzler, T; Werbovetz, KA | 1 |
| Dardonville, C; Kaiser, M; Lagartera, L; Ríos Martínez, CH | 1 |
| Battistuzzi, G; Giannini, G | 1 |
| Battistuzzi, G; Giannini, G; Vignola, D | 1 |
| Gilbert, IH; Kaiser, M; Mital, A; Murugesan, D; Yeates, C | 1 |
| Hao, Y; He, XL; He, Y; Liu, MY; Lv, F; Peng, SH; Qiu, WW; Wang, JH; Wang, YY; Yang, LF; Yi, Z | 1 |
| Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Saf, R; Seebacher, W; Weis, R | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chen, X; Chen, Y; Liao, F; Liu, M; Wang, W; Wen, J; Wu, Q; Xu, D | 1 |
| Zhao, B; Zheng, Z | 1 |
| Bujak, J; Kopytko, P; Pawlik, A; Tarnowski, M; Tkacz, M; Zgutka, K | 1 |
| Cao, F; Feng, B; Li, H; Lu, J; Tang, J; Tang, Z; Wang, H; Zhang, H; Zhang, Y | 1 |
| Bitton-Worms, K; Caspi, A; LeRoith, D; Rostoker, R; Shen-Orr, Z | 1 |
| Chen, JY; Chiou, YC; Li, WS; Shieh, JM; Tang, YA; Wang, YC | 1 |
| Bellail, AC; Hadjipanayis, CG; Hao, C; Li, C; Liu, T; Lv, G; Wang, Q; Wei, F; Zhang, G | 1 |
| Lubet, RA; Pan, J; Wang, Y; You, M; Zhang, Q | 1 |
| All-Ericsson, C; Axelson, M; Economou, MA; Girnita, L; Kvanta, A; Larsson, O; Menu, E; Rosengren, L; Seregard, S; van der Ploeg, I; Vasilcanu, D; Wu, J | 1 |
| Chen, G; Efstratiadis, A; Hibshoosh, H; Klinakis, A; Szabolcs, M; Xuan, S | 1 |
| Hosoyama, T; Keller, C; Nelon, LD; Ohshima-Hosoyama, S | 1 |
| Bagnoli, P; Cammalleri, M; Dal Monte, M; Filippi, L; Fiorini, P; Fortunato, P; la Marca, G; Martini, D; Ristori, C | 1 |
| Amaya, F; Izumi, Y; Miura, M; Mizukoshi, K; Sasaki, M; Shibasaki, M; Shimosato, G | 1 |
| Abraham, J; Hawkins, DS; Keller, C; Malempati, S; McHardy, SF; Michalek, JE; Nelon, LD; Prajapati, SI; Soundararajan, A; Zarzabal, LA | 1 |
| Abad, A; Del Olmo, E; Guerrero, E; López-Pérez, JL; Montenegro, G; San Feliciano, A | 1 |
| Asosingh, K; Axelson, M; De Raeve, H; Girnita, L; Jernberg-Wiklund, H; Larsson, O; Menu, E; Nilsson, K; Stromberg, T; Van Camp, B; Vanderkerken, K | 1 |
| Axelson, M; Coulton, L; Croucher, P; De Leenheer, E; De Raeve, H; Gallagher, O; Jernberg-Wiklund, H; Larsson, O; Menu, E; Nilsson, K; Van Camp, B; Van Valckenborgh, E; Vanderkerken, K | 1 |
| Axelson, M; Girnita, L; Hedin, U; Henderson, B; Larsson, O; Razuvaev, A; Roy, J | 1 |
| Hunstein, W; Körbling, M | 1 |
| Bastow, KF; Chang, JY; Chen, HX; Cheng, YC; Fu, Q; Guan, J; Guo, X; Jiang, Z; Lee, KH; Wang, HK; Zhu, XK | 1 |
| Walker, MD; Weiss, HD | 1 |
| Martino, C; Soloway, MS | 1 |
| Chang, LW; Chen, CF; Deng, JF; Yang, CM | 1 |
| Niell, HB; Soloway, MS; Wood, CA | 1 |
| Bailleul, F; Horvath, C; Lévi, F; Mathé, G; Mechkouri, M; Reinberg, A; Roulon, A | 1 |
| Shapiro, WR | 1 |
2 review(s) available for podophyllotoxin and Disease Models, Animal
| Article | Year |
|---|---|
In vitro chemoseparation as part of autologous bone marrow transplantation (ABMT) in hematologic malignancy.
Topics: Acute Disease; Animals; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Leukemia; Lymphoma; Mechlorethamine; Neoplastic Stem Cells; Photosensitivity Disorders; Podophyllotoxin; Pyrimidinones; Rats; Transplantation, Autologous | 1984 |
Chemotherapy in the treatment of malignant brain tumors.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cyclophosphamide; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Podophyllotoxin; Procarbazine; Vincristine | 1975 |
33 other study(ies) available for podophyllotoxin and Disease Models, Animal
| Article | Year |
|---|---|
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans.
Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis | 2008 |
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles.
Topics: Amidines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Disease Models, Animal; Female; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trypanosoma brucei rhodesiense | 2010 |
Antiprotozoal activity and DNA binding of N-substituted N-phenylbenzamide and 1,3-diphenylurea bisguanidines.
Topics: Animals; Antiparasitic Agents; Benzamides; Binding Sites; Cell Line; Cell Survival; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Female; Guanidines; Mice; Mice, Inbred Strains; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Surface Plasmon Resonance; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Urea | 2014 |
Exploring in vitro and in vivo Hsp90 inhibitors activity against human protozoan parasites.
Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Disease Models, Animal; HSP90 Heat-Shock Proteins; Humans; Mice; Parasitemia; Plasmodium falciparum; Protein Binding; Rats; Triazoles; Trypanosoma brucei rhodesiense | 2015 |
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms | 2015 |
Discovery and optimisation studies of antimalarial phenotypic hits.
Topics: Animals; Antimalarials; Cell Line; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Humans; Malaria; Mice; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Rats; Solubility; Structure-Activity Relationship | 2015 |
Synthesis of novel diterpenoid analogs with in-vivo antitumor activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Inhibitory Concentration 50; Mice; Structure-Activity Relationship | 2016 |
Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity.
Topics: Animals; Antimalarials; Cell Line; Cell Survival; Disease Models, Animal; Drug Resistance; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Structure-Activity Relationship | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Selective elimination of CML stem/progenitor cells by picropodophyllin in vitro and in vivo is associated with p53 activation.
Topics: Animals; Antigens, CD34; Apoptosis; Disease Models, Animal; Fetal Blood; Fusion Proteins, bcr-abl; Humans; In Vitro Techniques; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Transgenic; Microtubules; Neoplastic Stem Cells; Phosphorylation; Podophyllotoxin; Signal Transduction; Stem Cells; Transcriptional Activation; Tumor Suppressor Protein p53 | 2021 |
Insulin Growth Factor 1 Protects Neural Stem Cells Against Apoptosis Induced by Hypoxia Through Akt/Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase (Akt/MAPK/ERK) Pathway in Hypoxia-Ishchemic Encephalopathy.
Topics: Animals; Apoptosis; Cell Cycle; Cell Hypoxia; Cell Proliferation; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Hypoxia-Ischemia, Brain; Insulin-Like Growth Factor I; MAP Kinase Signaling System; Neural Stem Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Podophyllotoxin; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2017 |
Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chemotaxis; Disease Models, Animal; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Ligands; Male; Mice; Podophyllotoxin; Receptor, IGF Type 1; Receptor, Insulin; Rhabdomyosarcoma; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Protection of insulin‑like growth factor 1 on experimental peripheral neuropathy in diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Gene Expression Regulation; Humans; Insulin-Like Growth Factor I; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred NOD; Myelin Sheath; Neural Conduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Podophyllotoxin; Recombinant Proteins; Sciatic Nerve | 2018 |
Investigating new therapeutic strategies targeting hyperinsulinemia's mitogenic effects in a female mouse breast cancer model.
Topics: Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Growth Substances; Hyperinsulinism; Insulin; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Targeted Therapy; Peptides; Podophyllotoxin; Receptor, IGF Type 1; Therapies, Investigational | 2013 |
A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Damage; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stress; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mice; Microtubules; Mitosis; Models, Biological; Podophyllotoxin; Protein Multimerization; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.
Topics: Animals; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; Mutation; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2013 |
Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Humans; Lung Neoplasms; Mice; Podophyllotoxin; Receptor, IGF Type 1 | 2015 |
Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
Topics: Administration, Oral; Animals; Blotting, Western; Cell Culture Techniques; Choroid; Choroidal Neovascularization; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Injections, Intraperitoneal; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Pigment Epithelium of Eye; Podophyllotoxin; Receptor, IGF Type 1; Transfection; Vascular Endothelial Growth Factor A | 2008 |
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.
Topics: Animals; Breast Neoplasms; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Mice; Mice, Transgenic; Models, Biological; Podophyllotoxin; ras Proteins; Receptor, IGF Type 1; Signal Transduction | 2009 |
IGF-1 receptor inhibition by picropodophyllin in medulloblastoma.
Topics: Animals; Caspase 3; Cell Proliferation; Cerebellar Neoplasms; Disease Models, Animal; Gene Knockdown Techniques; Humans; Medulloblastoma; Mice; Podophyllotoxin; Receptor, IGF Type 1 | 2010 |
Role of the adrenergic system in a mouse model of oxygen-induced retinopathy: antiangiogenic effects of beta-adrenoreceptor blockade.
Topics: Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Animals; Animals, Newborn; Blood-Retinal Barrier; Blotting, Western; Capillary Permeability; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique, Indirect; Humans; Infant, Newborn; Injections, Intraperitoneal; Injections, Subcutaneous; Insulin-Like Growth Factor I; Intravitreal Injections; Male; Mice; Mice, Inbred C57BL; Oxygen; Podophyllotoxin; Propranolol; Receptor, IGF Type 1; Receptors, Adrenergic, beta; Retinal Neovascularization; Retinopathy of Prematurity; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A | 2011 |
Peripheral sensitization caused by insulin-like growth factor 1 contributes to pain hypersensitivity after tissue injury.
Topics: Animals; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Hyperalgesia; Insulin-Like Growth Factor I; Male; Oncogene Protein v-akt; Pain Measurement; Pain Threshold; Podophyllotoxin; Postoperative Complications; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, IGF Type 1; Skin | 2011 |
18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Fluorodeoxyglucose F18; Mice; Podophyllotoxin; Positron-Emission Tomography; Receptor, IGF Type 1; Rhabdomyosarcoma | 2012 |
Analgesic and anti-inflammatory activity of podophyllotoxin derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carbazoles; Cell Line, Tumor; Disease Models, Animal; Drugs, Chinese Herbal; HT29 Cells; Humans; Indomethacin; Inflammation; Juniperus; Male; Mice; Naphthalenes; Neoplasms; Pain; Plant Leaves; Podophyllotoxin | 2013 |
Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model.
Topics: Animals; Bone Marrow; Cell Proliferation; Disease Models, Animal; Enzyme Activation; In Vitro Techniques; Insulin-Like Growth Factor I; Mice; Mice, Inbred C57BL; Microcirculation; Mitogen-Activated Protein Kinase 1; Multiple Myeloma; Neovascularization, Pathologic; Paraproteins; Phosphorylation; Podophyllotoxin; Receptor, IGF Type 1; Survival Rate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2006 |
Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bone Neoplasms; Disease Models, Animal; Kaplan-Meier Estimate; Mice; Multiple Myeloma; Neovascularization, Pathologic; Podophyllotoxin; Receptor, IGF Type 1 | 2007 |
The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling.
Topics: Animals; Apoptosis; Cardiovascular Agents; Carotid Artery Injuries; Catheterization; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperplasia; Insulin-Like Growth Factor I; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Signal Transduction; Time Factors; Tunica Intima | 2007 |
Unique biochemical, cytotoxic, and antitumor activity of camptothecin and 4beta-amino-4'-O-demethylepipodophyllotoxin conjugates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle; Disease Models, Animal; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2000 |
Prophylaxis of bladder tumor implantation. Intravesical and systemic chemotherapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Disease Models, Animal; Doxorubicin; Female; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiotepa; Urinary Bladder; Urinary Bladder Neoplasms | 1976 |
Experimental podophyllotoxin (bajiaolian) poisoning: I. Effects on the nervous system.
Topics: Animals; Anterior Horn Cells; Cerebral Cortex; Disease Models, Animal; Male; Nerve Degeneration; Nervous System; Podophyllotoxin; Rats; Spinal Cord | 1992 |
Effect of concentration and time of drug exposure on clonal growth of murine bladder cancer.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cisplatin; Colony-Forming Units Assay; Disease Models, Animal; Doxorubicin; FANFT; Female; Fluorouracil; Maytansine; Methotrexate; Mice; Mice, Inbred C3H; Mitomycin; Mitomycins; Podophyllotoxin; Streptozocin; Time Factors; Trichothecenes; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 1985 |
Circadian rhythm in tolerance of mice for etoposide.
Topics: Animals; Body Weight; Circadian Rhythm; Disease Models, Animal; Drug Tolerance; Etoposide; Leukocyte Count; Light; Lung Diseases; Male; Mathematics; Mice; Podophyllotoxin | 1985 |
The chemotherapy of intracerebral vs subcutaneous murine gliomas. A comparative study of the effect of VM 26.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Disease Models, Animal; DNA, Neoplasm; Ependymoma; Glycosides; Injections; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiophenes; Thymidine; Tritium | 1974 |