Compounds > podophyllotoxin
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podophyllotoxin and Colorectal Cancer

podophyllotoxin has been researched along with Colorectal Cancer in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Leung, CH; Li, G; Liu, C; Ma, DL; Wang, HD; Wu, KJ; Zhong, HJ1
Chae, JI; Cho, SS; Joo, SH; Kwak, AW; Lee, MH; Lee, SO; Seo, JH; Shim, JH; Yoon, G1
Ahn, IH; Choi, IY; Choi, JR; Hwang, SG; Kang, AR; Kim, J; Kwon, JH; Lee, NG; Park, JK; Song, JY; Um, HD1
Bae, WK; Gamage, CDB; Kim, E; Kim, H; Kim, KK; Park, SY; Shim, JH; Taş, İ; Yang, Y; Yoon, G; Zhou, R1
Bellail, AC; Hadjipanayis, CG; Hao, C; Li, C; Liu, T; Lv, G; Wang, Q; Wei, F; Zhang, G1
Einstein, AB; Fleming, TR; Laufman, L; Macdonald, JS; Natale, RB; Oishi, N; Ungerleider, JS; Von Hoff, DD1

Trials

1 trial(s) available for podophyllotoxin and Colorectal Cancer

ArticleYear
VM-26 in colorectal carcinoma: a Southwest Oncology Group study.
    Investigational new drugs, 1990, Volume: 8, Issue:1

    Topics: Colorectal Neoplasms; Humans; Leukopenia; Multicenter Studies as Topic; Podophyllotoxin; Teniposide

1990

Other Studies

5 other study(ies) available for podophyllotoxin and Colorectal Cancer

ArticleYear
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Adenocarcinoma; Apoptosis; Caco-2 Cells; Cell Line; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Mitoxantrone; Models, Molecular; Molecular Structure; NEDD8 Protein; Structure-Activity Relationship; Tumor Suppressor Protein p53; Ubiquitin-Activating Enzymes

2018
Picropodophyllotoxin Induces G1 Cell Cycle Arrest and Apoptosis in Human Colorectal Cancer Cells via ROS Generation and Activation of p38 MAPK Signaling Pathway.
    Journal of microbiology and biotechnology, 2021, Dec-28, Volume: 31, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Survival; Colorectal Neoplasms; Endoplasmic Reticulum Stress; HCT116 Cells; Humans; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Podophyllotoxin; Reactive Oxygen Species

2021
JNC-1043, a Novel Podophyllotoxin Derivative, Exerts Anticancer Drug and Radiosensitizer Effects in Colorectal Cancer Cells.
    Molecules (Basel, Switzerland), 2022, Oct-18, Volume: 27, Issue:20

    Topics: Acetylcysteine; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Podophyllotoxin; Propidium; Radiation-Sensitizing Agents; Reactive Oxygen Species

2022
Deoxypodophyllotoxin Exerts Anti-Cancer Effects on Colorectal Cancer Cells Through Induction of Apoptosis and Suppression of Tumorigenesis.
    International journal of molecular sciences, 2019, May-28, Volume: 20, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Carcinogenesis; Colorectal Neoplasms; Drugs, Chinese Herbal; HT29 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Microtubules; Podophyllotoxin; Tubulin Modulators

2019
The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.
    BMC cancer, 2013, Nov-04, Volume: 13

    Topics: Animals; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Humans; Mice; Mutation; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2013