podophyllotoxin has been researched along with Carcinoma, Non-Small Cell Lung in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ai, D; Chen, Q; Gao, J; Lin, H; Liu, Q; Ruan, L; Tao, Y; Wang, L; Wang, X | 1 |
| Chae, JI; Cho, SS; Kim, E; Kwak, AW; Lee, MH; Liu, K; Oh, HN; Shim, JH; Yoon, G | 1 |
| Chae, JI; Cho, SS; Kim, E; Kim, HS; Kwak, AW; Lee, MH; Oh, HN; Seo, JH; Shim, JH; Yoon, G | 1 |
| Chen, M; Duan, H; Gao, Q; Jiang, Z; Song, Y; Sun, L; Wang, Y; Wu, M; Zhang, L; Zhang, S; Zhu, X | 1 |
| Chen, SW; Hui, L; Liu, JF; Qin, WW; Sang, CY; Xu, XH | 1 |
| Cho, HJ; Choi, JY; Hwang, SG; Kim, JI; Kim, WJ; Park, JK; Um, HD | 1 |
| Bergqvist, M; Bergström, S; Brandén, E; Ekman, S; Harmenberg, J; Holgersson, G; Jerling, M; Klockare, M; Koyi, H; Larsson, O; Lundström, KL; Ringbom, M | 1 |
| Abrahmsen, L; Alvfors, C; Axelson, M; Bergqvist, M; Bergström, S; Ekman, S; Eksborg, S; Frödin, JE; Harmenberg, J; Hedlund, Å; Jerling, M; Larsson, O; Ståhl, B; Wassberg, C | 1 |
| Cho, JH; Choi, JY; Hong, WG; Hwang, SG; Jung, CH; Kim, EM; Kim, J; Park, JK; Um, HD | 1 |
| Chen, S; Hui, L; Jia, Q; Ma, M; Sang, C; Wang, D; Wang, M; Wang, X | 1 |
| Cho, JH; Hong, WG; Hwang, SG; Jung, YJ; Lee, E; Lee, J; Park, JK; Um, HD | 1 |
| Cho, JH; Hong, WG; Hwang, SG; Kim, JI; Lee, E; Lee, J; Park, JK; Um, HD | 1 |
| Andor, G; Bergqvist, M; Bondarenko, I; Grechanaya, E; Harmenberg, J; Holgersson, G; Jerling, M; Klockare, M; Maximovich, A; Thureson, M | 1 |
| Chen, MC; Lee, KH; Li, TK; Pan, SL; Shi, Q; Teng, CM; Xiao, Z | 1 |
| Bunn, PA; Simon, GR | 1 |
| Cavalli, F; D'Incalci, M; De Fusco, M; de Jong, J; Hanauske, A; Kaeser-Fröhlich, A; Pagani, O; Sessa, C; Zucchetti, M | 1 |
| D'Incalci, M; Figoli, F; Lestuzzi, C; Monfardini, S; Sorio, R; Tirelli, U; Urso, R; Zanette, ML | 1 |
| Brandes, A; Chiarion Sileni, V; De Besi, P; Fornasiero, A; Fosser, VP; Paccagnella, A; Pappagallo, GL; Salvagno, L; Simioni, G; Vinante, O | 1 |
| Bagatella, M; Bonardi, G; Calciati, A; Ciuffreda, L; Donadio, M; Ferrati, P; Giaccone, G | 1 |
| Abad-Esteve, A; Fernandez, C; Monras, P; Moreno, I; Morera, J; Ribas-Mundo, M; Rosell, R; Ruiz, J | 1 |
1 review(s) available for podophyllotoxin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): recent developments.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Docetaxel; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Microtubules; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Paclitaxel; Palliative Care; Podophyllotoxin; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Taxoids; Teniposide; Treatment Outcome; Vinblastine; Vinorelbine | 2003 |
6 trial(s) available for podophyllotoxin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
A phase I pilot study of the insulin-like growth factor 1 receptor pathway modulator AXL1717 in combination with gemcitabine HCl and carboplatin in previously untreated, locally advanced, or metastatic non-small cell lung cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cohort Studies; Deoxycytidine; Female; Follow-Up Studies; Gemcitabine; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pilot Projects; Podophyllotoxin; Prognosis; Receptor, IGF Type 1; Tissue Distribution | 2015 |
A novel oral insulin-like growth factor-1 receptor pathway modulator and its implications for patients with non-small cell lung carcinoma: A phase I clinical trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Molecular Targeted Therapy; Neutropenia; Podophyllotoxin; Prospective Studies; Receptor, IGF Type 1; Signal Transduction; Treatment Outcome | 2016 |
Phase II randomized study of the IGF-1R pathway modulator AXL1717 compared to docetaxel in patients with previously treated, locally advanced or metastatic non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Disease Progression; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction; Survival Analysis; Taxoids; Treatment Outcome | 2017 |
Clinical and pharmacokinetic study of oral NK611, a new podophyllotoxin derivative.
Topics: Administration, Oral; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neutropenia; Podophyllotoxin; Thrombocytopenia | 1996 |
Cisplatin plus vindesine versus cisplatin plus VP16 versus doxorubicin plus cytoxan in non-small-cell carcinoma of the lung. A randomized study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Humans; Lung Neoplasms; Middle Aged; Podophyllotoxin; Random Allocation; Vindesine | 1986 |
A randomized study comparing platinum, doxorubicin, and VP-16 with platinum, 4'-epidoxorubicin, and VP-16 in patients with non-small-cell lung cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Doxorubicin; Epirubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Platinum; Podophyllotoxin; Random Allocation | 1987 |
13 other study(ies) available for podophyllotoxin and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Phenylacetates; Phosphatidylinositol 3-Kinases; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Tubulin | 2023 |
Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Molecular Docking Simulation; Molecular Targeted Therapy; Podophyllotoxin; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met | 2021 |
Deoxypodophyllotoxin Inhibits Cell Growth and Induces Apoptosis by Blocking EGFR and MET in Gefitinib-Resistant Non-Small Cell Lung Cancer.
Topics: Antineoplastic Agents; Apiaceae; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Podophyllotoxin; Proto-Oncogene Proteins c-met; Signal Transduction | 2021 |
Deoxypodophyllotoxin triggers necroptosis in human non-small cell lung cancer NCI-H460 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Culture Techniques; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Necrosis; Podophyllotoxin; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2013 |
DPMA, a deoxypodophyllotoxin derivative, induces apoptosis and anti-angiogenesis in non-small cell lung cancer A549 cells.
Topics: Adenosine; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Line, Tumor; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Neovascularization, Physiologic; Podophyllotoxin; Signal Transduction; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2013 |
Podophyllotoxin acetate enhances γ-ionizing radiation-induced apoptotic cell death by stimulating the ROS/p38/caspase pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cloning, Molecular; Gamma Rays; Gene Expression Regulation, Neoplastic; Humans; Mice; Molecular Structure; p38 Mitogen-Activated Protein Kinases; Podophyllotoxin; Reactive Oxygen Species | 2015 |
Podophyllotoxin acetate triggers anticancer effects against non-small cell lung cancer cells by promoting cell death via cell cycle arrest, ER stress and autophagy.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Microtubules; Podophyllotoxin | 2015 |
Newly synthesized podophyllotoxin derivative, LJ12, induces apoptosis and mitotic catastrophe in non-small cell lung cancer cells in vitro.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Methionine; Microtubules; Mitosis; Neoplasm Proteins; Podophyllotoxin | 2016 |
Γ-Ionizing radiation-induced activation of the EGFR-p38/ERK-STAT3/CREB-1-EMT pathway promotes the migration/invasion of non-small cell lung cancer cells and is inhibited by podophyllotoxin acetate.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Gamma Rays; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Podophyllotoxin; Signal Transduction; Transcription Factors | 2016 |
Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis.
Topics: A549 Cells; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Lung Neoplasms; Microtubules; Mitogen-Activated Protein Kinases; Podophyllotoxin; Topoisomerase Inhibitors | 2016 |
QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells.
Topics: Adenocarcinoma; Antigens, Neoplasm; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Caspase 3; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; Flow Cytometry; Humans; Lung Neoplasms; Piperidines; Podophyllotoxin; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2012 |
Pharmacokinetics of VM 26 given intrapericardially or intravenously in patients with malignant pericardial effusion.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Pericardial Effusion; Pericardium; Podophyllotoxin; Teniposide | 1987 |
Teniposide in the treatment of non-small cell lung carcinoma.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Teniposide | 1987 |