Page last updated: 2024-08-21

podophyllotoxin and Cancer of Prostate

podophyllotoxin has been researched along with Cancer of Prostate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
But, PP; Hon, PM; Jiang, RW; Li, LL; Li, SL; Shaw, PC; Xu, HX; Ye, WC; Zhou, JR; Zhou, Y1
Akunuri, R; Bhargava, SK; Bonam, SR; Kamal, A; Kumar, HMS; Naidu, VGM; Nayak, VL; Reddy, TS; Reddy, VG; Srihari, P1
Chen, X; Lei, D; Li, D; Li, M; Lin, H; Lin, K; Wang, G; Zheng, Q; Zhu, X1
Feng, J; Herman, HY; Jiang, RW; Li, J; Luo, C1
Ahn, S; Barrett, CM; Dalton, JT; Duke, CB; Hwang, DJ; Miller, DD; Yang, J1
Ahn, SC; Chatterjee, B; Cho, HJ; Kim, KY; Kim, SH; Kim, SY; Mirkheshti, N; Park, YM; Song, CS; Yu, HS; Yu, SN1
Loprinzi, CL; Trump, DL1
Fujita, K; Murayama, T; Sayama, T1
Beckmann, C; Flury, R; Frei, P; Holdener, E; Jungi, WF; Senn, HJ1
Caramia, G; Messana, V; Pavone-Macaluso, M; Rizzo, FP1
Birch, R; Einhorn, LH; Greco, FA; Troner, M; Walther, PJ; Williams, SD1
Ishibe, T; Moriyama, N; Nagafuji, T; Ohsumi, Y; Usui, T1
Suzuki, K1
Aota, Y; Kinjo, T; Mitsuya, H; Murase, T; Shimoji, T1
Messmer, B1

Trials

2 trial(s) available for podophyllotoxin and Cancer of Prostate

ArticleYear
Preliminary evaluation of VM-26: a new epipodophyllotoxin derivative, in the treatment of urogenital tumours.
    European urology, 1975, Volume: 1, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Papillary; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials as Topic; Drug Evaluation; Humans; Infusions, Parenteral; Leiomyosarcoma; Male; Mitosis; Neoplasm Metastasis; Podophyllotoxin; Prostatic Neoplasms; Teniposide; Teratoma; Testicular Neoplasms; Therapeutic Irrigation; Urinary Bladder Neoplasms

1975
Phase II study of etoposide for carcinoma of the prostate.
    Cancer treatment reports, 1986, Volume: 70, Issue:6

    Topics: Blood Cell Count; Clinical Trials as Topic; Drug Evaluation; Etoposide; Hematologic Diseases; Humans; Male; Podophyllotoxin; Prostatic Neoplasms

1986

Other Studies

14 other study(ies) available for podophyllotoxin and Cancer of Prostate

ArticleYear
Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell lines.
    Journal of natural products, 2007, Volume: 70, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Berberidaceae; Drug Screening Assays, Antitumor; Humans; Lignans; Male; Molecular Structure; Plant Roots; Plants, Medicinal; Podophyllotoxin; Prostatic Neoplasms; Rhizome; Tumor Cells, Cultured

2007
4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Humans; Male; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Molecular Structure; Podophyllotoxin; Prostatic Neoplasms; Reactive Oxygen Species; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazoles; Tumor Cells, Cultured

2018
Picropodophyllin Inhibits the Proliferation of Human Prostate Cancer DU145 and LNCaP Cells via ROS Production and PI3K/AKT Pathway Inhibition.
    Biological & pharmaceutical bulletin, 2022, Volume: 45, Issue:8

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Male; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Podophyllotoxin; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species

2022
Absolute configuration of podophyllotoxone and its inhibitory activity against human prostate cancer cells.
    Chinese journal of natural medicines, 2015, Volume: 13, Issue:1

    Topics: Antineoplastic Agents; Berberidaceae; Cell Line, Tumor; Dose-Response Relationship, Drug; G2 Phase; Humans; Hydrogen Bonding; Male; Molecular Conformation; Molecular Docking Simulation; Phytotherapy; Plant Extracts; Plant Roots; Podophyllotoxin; Polymerization; Prostatic Neoplasms; Tubulin; Tubulin Modulators

2015
A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:2

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Binding Sites; Binding, Competitive; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Indoles; Inhibitory Concentration 50; Male; Maximum Tolerated Dose; Mice; Mice, Inbred ICR; Mice, Nude; Microtubules; Molecular Structure; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Podophyllotoxin; Prostatic Neoplasms; Survival Rate; Tubulin; Tubulin Modulators; Vinblastine; Xenograft Model Antitumor Assays

2011
Interplay of reactive oxygen species, intracellular Ca2+ and mitochondrial homeostasis in the apoptosis of prostate cancer cells by deoxypodophyllotoxin.
    Journal of cellular biochemistry, 2013, Volume: 114, Issue:5

    Topics: Apoptosis; bcl-2-Associated X Protein; Calcium; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Egtazic Acid; Enzyme Activation; G2 Phase Cell Cycle Checkpoints; Homeostasis; Humans; Intracellular Space; M Phase Cell Cycle Checkpoints; Male; Membrane Potential, Mitochondrial; Mitochondria; Models, Biological; Podophyllotoxin; Prostatic Neoplasms; Protein Transport; Reactive Oxygen Species

2013
Phase II trial of etoposide in advanced prostate cancer.
    Cancer treatment reports, 1984, Volume: 68, Issue:9

    Topics: Aged; Bone Marrow Diseases; Drug Evaluation; Etoposide; Humans; Infusions, Parenteral; Male; Middle Aged; Podophyllotoxin; Prostatic Neoplasms

1984
[Effect of etoposide for pulmonary metastases from urogenital tract cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:11

    Topics: Adenocarcinoma; Administration, Oral; Aged; Carcinoma, Transitional Cell; Etoposide; Humans; Infusions, Parenteral; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Prostatic Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms

1984
[Therapeutic experiences using the new podophyllotoxin derivative VP 16-213 in malignant human tumors].
    Schweizerische medizinische Wochenschrift, 1975, Oct-18, Volume: 105, Issue:42

    Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma; Carcinoma, Small Cell; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Prostatic Neoplasms; Remission, Spontaneous

1975
[Study of anti-cancer chemotherapy of prostatic carcinoma. I. Comparative study of ifosfamide and VIP against a hormone-independent human prostatic carcinoma cell line].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cells, Cultured; Cisplatin; Humans; Ifosfamide; Male; Podophyllotoxin; Prostatic Neoplasms

1987
[Phase II study of etoposide (VP-16-213) in genitourinary tumors. VP-16-213 Genitourinary Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:9

    Topics: Adult; Aged; Alopecia; Anorexia; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Male; Middle Aged; Nausea; Podophyllotoxin; Prostatic Neoplasms; Testicular Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms

1986
[Effect of etoposide for urogenital tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Aged; Antineoplastic Agents, Phytogenic; Drug Administration Schedule; Etoposide; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Pancreatic Neoplasms; Podophyllotoxin; Prostatic Neoplasms; Rhabdomyosarcoma; Ureteral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms

1985
[Collaborative phase II study of etoposide (NK-171). Urological Cooperative Study Group of etoposide (NK-171)].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:8

    Topics: Administration, Oral; Alopecia; Anorexia; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Infusions, Parenteral; Kidney Neoplasms; Male; Nausea; Podophyllotoxin; Prostatic Neoplasms; Testicular Neoplasms; Urogenital Neoplasms

1985
[Plasma iron turnover before and following cytostatic therapy and its signifiance as indicator of tumor activity].
    Klinische Wochenschrift, 1968, Dec-01, Volume: 46, Issue:23

    Topics: Antineoplastic Agents; Breast Neoplasms; Female; Follow-Up Studies; Humans; Iron; Iron Isotopes; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Prostatic Neoplasms; Rectal Neoplasms; Thyroid Neoplasms; Time Factors; Urinary Bladder Neoplasms

1968