Page last updated: 2024-08-21

podophyllotoxin and Breast Cancer

podophyllotoxin has been researched along with Breast Cancer in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (50.79)	18.7374
1990's	6 (9.52)	18.2507
2000's	6 (9.52)	29.6817
2010's	16 (25.40)	24.3611
2020's	3 (4.76)	2.80

Authors

Authors	Studies
Chakraborti, AK; Cushman, M; Gopal, D; Hamel, E; Lin, CM; Nagarathnam, D	1
Hamel, E; Kuo, SC; Lednicer, D; Lee, KH; Li, L; Lin, CM; Wang, HK; Wu, TS	1
Boykin, DW; Hu, L; Jiang, JD; Li, Y; Li, ZR; Ling, YH; Qu, J	1
Bhoyar, AS; Chaudhary, V; Dhaked, HP; Guchhait, SK; Panda, D; Venghateri, JB	1
Abdel Wahab, AHA; Abdelhameid, MK; Ashmawy, AM; El-Deen, IM; Mohamed, KO; Zaki, I	1
Chanda, D; Dudi, RK; Fatima, K; Iqbal, H; Khan, F; Kumar, Y; Luqman, S; Mondhe, DM; Negi, AS; Shanker, K; Tabassum, M; Verma, AK	1
Armstrong, GT; Arnold, MA; Bhatia, S; Howell, RM; Hudson, MM; Im, C; Lu, Z; Neglia, JP; Ness, KK; Robison, LL; Sapkota, Y; Sharafeldin, N; Spector, LG; Turcotte, LM; Wang, Z; Yasui, Y; Yuan, Y	1
Bian, W; Chen, M; He, P; Li, Y; Lu, X; Ren, X; Vasilatos, SN; Yao, B; Yao, C; Zhang, X	1
Disouza, JI; Kumbhar, PS; Manjappa, AS; Patil, OB; Sakate, AM	1
Li, SD; Roy, A; Undzys, E; Yang, Y; Zhao, Y	1
Cai, Q; Chen, Q; Hao, H; Wang, G; Wu, B; Zang, X; Zhang, J; Zheng, X; Zhou, F; Zhu, X	1
Chen, X; Deng, M; Lv, S; Tang, Z; Zhang, D; Zhang, X; Zhou, H	1
Bao, X; Gao, Y; Li, F; Sun, H; Wang, Y; Wei, N; Wu, S; Xiao, Z; Zhang, D; Zhang, G	1
Belli, S; Botti, G; Carriero, MV; De Vincenzo, A; Franco, P; Iaccarino, I; Ranson, M; Stoppelli, MP; Telesca, M	1
Bitton-Worms, K; Caspi, A; LeRoith, D; Rostoker, R; Shen-Orr, Z	1
Chang, WW; Chang, WY; Fu, CH; Lai, A; Lin, RJ; Yu, AL; Yu, J; Yu, JC	1
Adil, SF; Bhadra, U; Ganesh, R; Kamal, A; Pal-Bhadra, M; Pushpavalli, SN; Ramaiah, MJ; Sarma, P; Tamboli, JR	1
Beauregard, AP; Benzina, S; Bos, A; Carroll, M; Colquhoun, CD; Gray, CA; Harquail, J; Jean, S; Robichaud, GA	1
Basha, SA; Bhadra, MP; Bhadra, U; Kamal, A; Kavi Kishor, PB; Lavanya, A; Ramaiah, MJ; Srinivas, C; Yerramsetty, S	1
Álvarez-Berber, L; Meneses-Acosta, A; Peña-Morán, OA; Rodríguez-López, V; Villarreal, ML	1
Belaaloui, G; Jiang, ZZ; Khaled, M; Zhang, LY; Zhu, X	1
Annereau, JP; Bailly, C; Barret, JM; Brel, V; Delcros, JG; Guilbaud, N; Guminski, Y; Imbert, T; Kruczynski, A; Lansiaux, A; Vispé, S	1
Chen, G; Efstratiadis, A; Hibshoosh, H; Klinakis, A; Szabolcs, M; Xuan, S	1
Buschmann, MD; Gal, S; Jean, M; Li, Z; Liao, S; Merzouki, A; Slilaty, SN; Young, RS	1
Bisaria, VS; Chattopadhyay, S; Panda, AK; Srivastava, AK	1
Kennedy, BJ; Raghavan, D; Vogelzang, NJ	1
Calciati, A; Conte, PF; Giaccone, G; Musella, R	1
Crivellari, D; Franchin, G; Galligioni, E; Grigoletto, E; Talamini, R; Tirelli, U; Trovó, MG; Tumolo, S; Veronesi, A	1
Aisner, J; Konits, PH; Morris, D; Van Echo, DA; Wiernik, PH	1
Alburquerque Carbuccia, H; Madrigal Alonso, PL; Perez Manga, G	1
Cirera, L; Doncel, F; Estapé, J; Millá, A	1
Alburquerque Carbuccia, H; Madrigal Alonso, P; Perez Manga, G	1
Demitrish, M; Duffin, H; Enochs, K; Groshko, G; Lockhard, C; Maniscalco-Greb, E; Vaughn, CB	1
Brunner, KW; Cavalli, F; Jungi, WF	1
Esparza, L; Hortobagyi, GN; Issell, B; Schell, FC; Yap, HY	1
Höffken, K	1
Ahmann, DL; Decker, DA; Eagan, RT; Hahn, RG; Ingle, JN; Rubin, J	1
Schulz, JJ; Speckhart, VJ; Spremulli, E; Wampler, GL	1
Hagen, K; Kong, AN; Mandlekar, S; Roninson, IB; Shtil, AA; Tan, TH; Walter, RJ; Yu, R	1
Björkholm, M; Gruber, A; Hansson, M; Steingrimsdottir, H; Svensson, A	1
Desprez, PY; Itahana, Y; Murata, K; Singh, J	1
Falkson, G; Falkson, HC; van den Bergh, JA; van der Merwe, AM; van Dyk, JJ; van Eden, EB	1
Gautier, H; Huguenin, P; Lheritier, J; Mathé, G; Morin, P; Palangie, T; Parrot, R; Poisson, M; Pouillart, P	1
Garcia-Giralt, E; Jouve, M; Magdelenat, H; Palangie, T; Pouillart, P	1
Carter, SK; Livingston, RB	1
Ahmann, DL; Bisel, HF; Eagan, RT	1
Ahmann, DL; Bisel, HF; Eagan, RT; Edmonson, JH; Frytak, S; Hahn, RG; O'Connell, MJ	1
Amiel, JL; Baron, A; Huguenin, P; Laparre, Ch; Mathé, G; Morin, P; Parrot, R; Pouillart, P; Schwarzenberg, L	1
Bonera, E; Calvi, A; Lombardi, C; Savio, A; Savio, E	1
Albain, KS; Le Beau, MM; Schumacher, H; Ullirsch, R	1
Boas, J; Dombernowsky, P; Engelholm, SA; Hansen, OP; Rasmussen, D	1
Carpenter, JT; Cox, EB; Raney, M; Vogel, CL	1
Athanassiades, P; Bacoyiannes, H; Kontoyiannes, D	1
Brachetti, A; Leonhardt, A; Limburg, H; Osswald, H; Schmähl, D	1
DEJAGER, ME; FALKSON, G	1
FRIDRICH, R; ZDANSKY, E	1
FRIDRICH, R	1
Halama, J	1
Schärtl, W	1
Assmann, H	1
Becher, R; Gebhardt, KH	1
Messmer, B	1
Hatzenberger, H	1

Reviews

2 review(s) available for podophyllotoxin and Breast Cancer

Article	Year
Plant products in cancer chemotherapy. Cancer treatment reports, 1976, Volume: 60, Issue:8 Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Lymphoma; Neoplasms; Phytotherapy; Plants, Medicinal; Podophyllotoxin; Vinblastine; Vinca Alkaloids; Vincristine	1976
Implication of prior treatment with drug combinations including inhibitors of topoisomerase II in therapy-related monocytic leukemia with a 9;11 translocation. Genes, chromosomes & cancer, 1990, Volume: 2, Issue:1 Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Iatrogenic Disease; Leukemia, Monocytic, Acute; Mastectomy, Radical; Middle Aged; Podophyllotoxin; Radiotherapy; Tamoxifen; Topoisomerase II Inhibitors; Translocation, Genetic	1990

Article

Year

Plant products in cancer chemotherapy.

Cancer treatment reports, 1976, Volume: 60, Issue:8

Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Lymphoma; Neoplasms; Phytotherapy; Plants, Medicinal; Podophyllotoxin; Vinblastine; Vinca Alkaloids; Vincristine

1976

Implication of prior treatment with drug combinations including inhibitors of topoisomerase II in therapy-related monocytic leukemia with a 9;11 translocation.

Genes, chromosomes & cancer, 1990, Volume: 2, Issue:1

Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Iatrogenic Disease; Leukemia, Monocytic, Acute; Mastectomy, Radical; Middle Aged; Podophyllotoxin; Radiotherapy; Tamoxifen; Topoisomerase II Inhibitors; Translocation, Genetic

1990

Trials

8 trial(s) available for podophyllotoxin and Breast Cancer

Article	Year
VP-16-213 (etoposide): the mandrake root from Issyk-Kul. The American journal of medicine, 1982, Volume: 72, Issue:1 Topics: Animals; Breast Neoplasms; Carcinoma, Small Cell; Cell Cycle; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dysgerminoma; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Mice; Podophyllotoxin	1982
Doxorubicin plus VP-16-213 for the treatment of refractory breast carcinoma. American journal of clinical oncology, 1982, Volume: 5, Issue:5 Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Infusions, Parenteral; Leukopenia; Middle Aged; Podophyllotoxin; Thrombocytopenia	1982
[Randomized phase II study with VP-16-213 (etoposide) in the treatment of advanced breast cancer]. Onkologie, 1981, Volume: 4, Issue:2 Topics: Administration, Oral; Breast Neoplasms; Drug Evaluation; Etoposide; Female; Humans; Injections, Intravenous; Middle Aged; Podophyllotoxin; Prognosis; Random Allocation	1981
An evaluation of two schedules of VP-16 and adriamycin in patients with advanced breast cancer. Oncology, 1980, Volume: 37, Issue:3 Topics: Bone Marrow; Breast Neoplasms; Cardiomyopathies; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Podophyllotoxin; Remission, Spontaneous; Time Factors	1980
Treatment of malignant gliomas and brain metastases in adults using a combination of adriamycine, VM 26, and CCNU. Results of a type II trial. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:62 Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Glioma; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Podophyllotoxin; Teniposide	1977
Evaluation of VP-16 and the combination of adriamycin and vincristine in advanced breast cancer. Oncology, 1976, Volume: 33, Issue:3 Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Neoplasm Metastasis; Podophyllotoxin; Remission, Spontaneous; Vincristine	1976
Phase II evaluation of VP-16-213 (NSC-141540) and cytembena (NSC-104801) in patients with advanced breast cancer. Cancer treatment reports, 1976, Volume: 60, Issue:5 Topics: Acrylates; Breast Neoplasms; Drug Therapy, Combination; Etoposide; Female; Humans; Podophyllotoxin	1976
Etoposide (VP-16-213) and cis-dichlorodiammineplatinum (DDP) in advanced breast carcinoma resistant to previous chemotherapy. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:2 Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Vincristine	1986

Other Studies

53 other study(ies) available for podophyllotoxin and Breast Cancer

Article	Year
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization. Journal of medicinal chemistry, 1991, Volume: 34, Issue:8 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemical Phenomena; Chemistry; Colchicine; Colonic Neoplasms; Humans; Lung Neoplasms; Melanoma; Molecular Structure; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	1991
Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. Journal of medicinal chemistry, 1994, Apr-15, Volume: 37, Issue:8 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cattle; Cell Division; Central Nervous System Neoplasms; Colonic Neoplasms; Female; Humans; Leukemia; Lung Neoplasms; Molecular Structure; Polymers; Quinolones; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	1994
Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors. Journal of medicinal chemistry, 2006, Oct-19, Volume: 49, Issue:21 Topics: Animals; Antimitotic Agents; Apoptosis; Breast Neoplasms; Carbazoles; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Sulfonamides; Transplantation, Heterologous; Tumor Suppressor Protein p53	2006
Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl Moiety. Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7 Topics: Apoptosis; Bibenzyls; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Imidazoles; Microtubules; Mitosis; Molecular Structure; Prodrugs; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2016
Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line. European journal of medicinal chemistry, 2018, Aug-05, Volume: 156 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Drug Design; Female; Humans; MCF-7 Cells; Topoisomerase II Inhibitors; Triazines; Tubulin; Tubulin Modulators	2018
Antiproliferative activity of diarylnaphthylpyrrolidine derivative via dual target inhibition. European journal of medicinal chemistry, 2020, Feb-15, Volume: 188 Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; G2 Phase Cell Cycle Checkpoints; Humans; Male; Mice; Molecular Docking Simulation; Naphthalenes; Pyrrolidines; Topoisomerase II Inhibitors; Tubulin Modulators	2020
Polygenic Risk and Chemotherapy-Related Subsequent Malignancies in Childhood Cancer Survivors: A Childhood Cancer Survivor Study and St Jude Lifetime Cohort Study Report. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 09-20, Volume: 41, Issue:27 Topics: Adult; Breast Neoplasms; Cancer Survivors; Child; Cohort Studies; Female; Humans; Neoplasms, Second Primary; Podophyllotoxin; Risk Factors	2023
Transferrin receptor-targeted redox/pH-sensitive podophyllotoxin prodrug micelles for multidrug-resistant breast cancer therapy. Journal of materials chemistry. B, 2019, 10-14, Volume: 7, Issue:38 Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Survival; Disulfides; Drug Resistance, Multiple; Female; Glutathione; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Mice; Micelles; Nanoparticles; Oxidation-Reduction; Paclitaxel; Podophyllotoxin; Polyethylene Glycols; Prodrugs; Receptors, Transferrin	2019
Podophyllotoxin-polyacrylic acid conjugate micelles: improved anticancer efficacy against multidrug-resistant breast cancer. Journal of the Egyptian National Cancer Institute, 2020, Nov-16, Volume: 32, Issue:1 Topics: Acrylic Resins; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Micelles; Podophyllotoxin	2020
Comparison of Tumor Penetration of Podophyllotoxin-Carboxymethylcellulose Conjugates with Various Chemical Compositions in Tumor Spheroid Culture and In Vivo Solid Tumor. Bioconjugate chemistry, 2017, 05-17, Volume: 28, Issue:5 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carboxymethylcellulose Sodium; Cell Proliferation; Drug Carriers; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Podophyllotoxin; Polymers; Spheroids, Cellular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2017
A Promising Microtubule Inhibitor Deoxypodophyllotoxin Exhibits Better Efficacy to Multidrug-Resistant Breast Cancer than Paclitaxel via Avoiding Efflux Transport. Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:5 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Female; G2 Phase Cell Cycle Checkpoints; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubules; Neoplasm Proteins; Paclitaxel; Podophyllotoxin	2018
A polypeptide based podophyllotoxin conjugate for the treatment of multi drug resistant breast cancer with enhanced efficiency and minimal toxicity. Acta biomaterialia, 2018, Volume: 73 Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Hemolysis; Humans; Maximum Tolerated Dose; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasm Transplantation; Peptides; Podophyllotoxin; Polyethylene Glycols; Polyglutamic Acid	2018
DNA damage and apoptosis induced by a potent orally podophyllotoxin derivative in breast cancer. Cell communication and signaling : CCS, 2018, 09-03, Volume: 16, Issue:1 Topics: Administration, Oral; Animals; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; Female; Humans; MCF-7 Cells; Mice; Molecular Docking Simulation; Phosphatidylinositol 3-Kinases; Podophyllotoxin; Poly-ADP-Ribose Binding Proteins; Protein Conformation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Reactive Oxygen Species; Xenograft Model Antitumor Assays	2018
Paracrine recruitment and activation of fibroblasts by c-Myc expressing breast epithelial cells through the IGFs/IGF-1R axis. International journal of cancer, 2019, 11-15, Volume: 145, Issue:10 Topics: Breast; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Differentiation; Cell Line; Coculture Techniques; Culture Media, Conditioned; Epithelial Cells; Female; Humans; Insulin-Like Growth Factor Binding Protein 6; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Neoplasm Invasiveness; Podophyllotoxin; Primary Cell Culture; Proto-Oncogene Proteins c-myc; Receptor, IGF Type 1; RNA, Small Interfering; Signal Transduction; Tumor Cells, Cultured; Tumor Microenvironment	2019
Investigating new therapeutic strategies targeting hyperinsulinemia's mitogenic effects in a female mouse breast cancer model. Endocrinology, 2013, Volume: 154, Issue:5 Topics: Animals; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Female; Growth Substances; Hyperinsulinism; Insulin; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Targeted Therapy; Peptides; Podophyllotoxin; Receptor, IGF Type 1; Therapies, Investigational	2013
The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors. Breast cancer research : BCR, 2013, May-12, Volume: 15, Issue:3 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor I; Mice; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Xenograft Model Antitumor Assays	2013
Quinazolino linked 4β-amidopodophyllotoxin conjugates regulate angiogenic pathway and control breast cancer cell proliferation. Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21 Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; G2 Phase Cell Cycle Checkpoints; Human Umbilical Vein Endothelial Cells; Humans; M Phase Cell Cycle Checkpoints; MCF-7 Cells; Membrane Potential, Mitochondrial; Neovascularization, Physiologic; Podophyllotoxin; Quinazolinones; Signal Transduction	2013
Deoxypodophyllotoxin isolated from Juniperus communis induces apoptosis in breast cancer cells. Anti-cancer agents in medicinal chemistry, 2015, Volume: 15, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biological Products; Breast Neoplasms; Carboxylic Acids; Caspases; Cell Line, Tumor; Diterpenes; Drugs, Chinese Herbal; Female; Humans; Juniperus; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Plant Extracts; Plants, Medicinal; Podophyllotoxin; Signal Transduction; Tetrahydronaphthalenes	2015
Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer. PloS one, 2015, Volume: 10, Issue:11 Topics: Apoptosis; Breast Neoplasms; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; MCF-7 Cells; MicroRNAs; Models, Molecular; Molecular Docking Simulation; Neovascularization, Pathologic; Podophyllotoxin; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Quinazolines; RNA Interference; RNA, Small Interfering; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A	2015
Cytotoxicity, Post-Treatment Recovery, and Selectivity Analysis of Naturally Occurring Podophyllotoxins from Bursera fagaroides var. fagaroides on Breast Cancer Cell Lines. Molecules (Basel, Switzerland), 2016, Aug-04, Volume: 21, Issue:8 Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Bursera; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Lignans; MCF-7 Cells; Molecular Structure; Plant Extracts; Podophyllotoxin	2016
Antitumor effect of Deoxypodophyllotoxin on human breast cancer xenograft transplanted in BALB/c nude mice model. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:10 Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Breast Neoplasms; Cell Line, Tumor; Docetaxel; Drugs, Chinese Herbal; Etoposide; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Podophyllotoxin; Taxoids; Xenograft Model Antitumor Assays	2016
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system. Cancer research, 2008, Dec-01, Volume: 68, Issue:23 Topics: Animals; Binding, Competitive; Biogenic Polyamines; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Delivery Systems; Etoposide; Female; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Neoplasms; Podophyllotoxin; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays	2008
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. Proceedings of the National Academy of Sciences of the United States of America, 2009, Feb-17, Volume: 106, Issue:7 Topics: Animals; Breast Neoplasms; Disease Models, Animal; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Mice; Mice, Transgenic; Models, Biological; Podophyllotoxin; ras Proteins; Receptor, IGF Type 1; Signal Transduction	2009
Adva-27a, a novel podophyllotoxin derivative found to be effective against multidrug resistant human cancer cells. Anticancer research, 2012, Volume: 32, Issue:10 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Fluorine Compounds; Glycosides; Humans; Male; Microsomes, Liver; Monosaccharides; Podophyllotoxin; Rats; Rats, Sprague-Dawley; Small Cell Lung Carcinoma; Topoisomerase II Inhibitors	2012
Cytotoxicity of in vitro produced podophyllotoxin from Podophyllum hexandrum on human cancer cell line. Natural product research, 2004, Volume: 18, Issue:1 Topics: Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Keratolytic Agents; Podophyllotoxin; Podophyllum; Tumor Cells, Cultured	2004
Combination chemotherapy for metastatic brain tumors. Tumori, 1981, Dec-31, Volume: 67, Issue:6 Topics: Adenocarcinoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Small Cell; Doxorubicin; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Nitrosourea Compounds; Podophyllotoxin; Prognosis; Teniposide; Tomography, X-Ray Computed	1981
Phase II study of VM 26 in extensively pretreated breast cancer. American journal of clinical oncology, 1984, Volume: 7, Issue:5 Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Female; Humans; Male; Middle Aged; Podophyllotoxin; Teniposide	1984
Mitomycin-C, VP16-213 combination as third line chemotherapy in advanced breast cancer. Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3 Topics: Adult; Breast Neoplasms; Drug Therapy, Combination; Etoposide; Female; Humans; Middle Aged; Mitomycin; Mitomycins; Podophyllotoxin	1982
VP16-213 and cyclophosphamide in advanced breast cancer. A phase II study. Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:3 Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Etoposide; Female; Humans; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Prognosis	1983
Adriamycin and VP16-213 combination treatment for breast cancer previously treated by the CMF regimen. Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Podophyllotoxin	1982
VP-16 and adriamycin in patients with advanced breast cancer. American journal of clinical oncology, 1982, Volume: 5, Issue:5 Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Podophyllotoxin; Prednisone; Thrombocytopenia; Vincristine; Vomiting	1982
Phase II study of VP16-213 (etoposide) in refractory metastatic breast carcinoma. Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3 Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Drug Resistance; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin	1982
Etoposide in the treatment of refractory breast cancer. Cancer treatment reviews, 1982, Volume: 9 Suppl Topics: Antineoplastic Agents; Breast Neoplasms; Drug Therapy, Combination; Etoposide; Female; Humans; Podophyllotoxin	1982
Phase II study of VM-26 in adult malignancies. Cancer treatment reports, 1980, Volume: 64, Issue:1 Topics: Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide; Thrombocytopenia	1980
Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells. Oncogene, 1999, Jan-14, Volume: 18, Issue:2 Topics: Apoptosis; Breast Neoplasms; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Colchicine; Egtazic Acid; Enzyme Activation; Humans; Microtubules; Nocodazole; Paclitaxel; Podophyllotoxin; Tumor Cells, Cultured; Vincristine	1999
Immune reconstitution after autologous hematopoietic stem cell transplantation in relation to underlying disease, type of high-dose therapy and infectious complications. Haematologica, 2000, Volume: 85, Issue:8 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Breast Neoplasms; Carmustine; Cell Lineage; Combined Modality Therapy; Cytarabine; Disease Susceptibility; Female; Graft Survival; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Infections; Lymphocyte Count; Lymphocyte Subsets; Lymphopenia; Male; Melphalan; Middle Aged; Podophyllotoxin; Sweden; Transplantation Conditioning; Transplantation, Autologous	2000
Constitutive expression of the Id-1 promoter in human metastatic breast cancer cells is linked with the loss of NF-1/Rb/HDAC-1 transcription repressor complex. Oncogene, 2002, Mar-14, Volume: 21, Issue:12 Topics: Binding Sites; Blotting, Western; Breast Neoplasms; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Electrophoretic Mobility Shift Assay; Epithelial Cells; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Helix-Loop-Helix Motifs; Histone Deacetylase 1; Histone Deacetylases; Humans; Inhibitor of Differentiation Protein 1; Mutation; Neoplasm Invasiveness; Neurofibromin 1; Plasmids; Podophyllin; Podophyllotoxin; Precipitin Tests; Promoter Regions, Genetic; Repressor Proteins; Retinoblastoma Protein; Transcription Factors; Transfection; Tumor Cells, Cultured	2002
A clinical trial of the oral form of 4'-demethyl-epipodophyllotoxin-beta-D ethylidene glucoside (NSC 141540) VP 16-213. Cancer, 1975, Volume: 35, Issue:4 Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Glucosides; Humans; Leukemia, Myeloid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mesothelioma; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Urinary Bladder Neoplasms	1975
[Effectiveness of VM 26, mitomycine C and methotrexate in advanced breast cancer refractory to a four drug combination (author's transl)]. Bulletin du cancer, 1979, Volume: 66, Issue:5 Topics: Adult; Aged; Breast Neoplasms; Drug Resistance; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Podophyllotoxin; Teniposide	1979
[Chemotherapeutic combinations of mutually potentializing drugs. 1-Application to the treatment of breast cancers]. La Nouvelle presse medicale, 1975, Mar-08, Volume: 4, Issue:10 Topics: Aged; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neurologic Manifestations; Nitrosourea Compounds; Podophyllotoxin; Vincristine; Vomiting	1975
Bilateral breast involvement in a 71-year-old white man with lambda light chain disease. Regression after a new chemotherapy combination. A case report. Tumori, 1992, Feb-29, Volume: 78, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone; Humans; Immunoglobulin lambda-Chains; Male; Melphalan; Multiple Myeloma; Peptichemio; Podophyllotoxin; Prednisone; Remission Induction; Time Factors	1992
Phase II study of teniposide in advanced breast cancer. Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:6 Topics: Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Intravenous; Leukopenia; Middle Aged; Podophyllotoxin; Teniposide; Thrombocytopenia	1990
Phase II evaluation of teniposide (VM-26) in metastatic breast carcinoma. A Southeastern Cancer Study Group trial. Investigational new drugs, 1988, Volume: 6, Issue:1 Topics: Adult; Aged; Breast Neoplasms; Drug Evaluation; Drug Resistance; Female; Humans; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Teniposide	1988
[Clinical experiences with a combination therapy of metastasising genital and mammary carcinomas (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1974, Nov-22, Volume: 116, Issue:47 Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Cyclophosphamide; Cytidine; Drug Therapy, Combination; Female; Genital Neoplasms, Female; Humans; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Podophyllotoxin; Postoperative Care; Prognosis; Remission, Spontaneous; Thymidine; Uterine Cervical Neoplasms; Vinblastine	1974
CATALASE ACTIVITY IN THE EPIDERMIS OF PATIENTS WITH ADVANCED CANCER. Nature, 1964, Apr-11, Volume: 202 Topics: Antineoplastic Agents; Breast Neoplasms; Carbamates; Catalase; Clinical Enzyme Tests; Cobalt Isotopes; Cyclophosphamide; Drug Therapy; Epidermis; Fluorouracil; Humans; Neoplasms; Podophyllum; Skin	1964
[TRIAL OF A CHEMOTHERAPEUTIC PREVENTION OF RECURRENCE AND METASTASIS OF OPERATIVE AND SUBSEQUENTLY IRRADIATED BREAST CARCINOMA]. Schweizerische medizinische Wochenschrift, 1964, Jul-11, Volume: 94 Topics: Breast Neoplasms; Carcinoma; Drug Therapy; Humans; Mastectomy; Neoplasm Recurrence, Local; Neoplasms; Podophyllum	1964
[THE VALUE OF THE ADDITION OF A PODOPHYLLUM TOXIN COMPOUND TO THE SURGICAL AND RADIOLOGICAL TREATMENT OF MAMMARY CARCINOMAS]. Radiologia clinica, 1965, Volume: 34 Topics: Antineoplastic Agents; Breast Neoplasms; Humans; Neoplasms; Podophyllin; Podophyllum; Toxicology	1965
[Experiences with the cytostatic podophyllin therapy]. Munchener medizinische Wochenschrift (1950), 1967, Feb-18, Volume: 108, Issue:7 Topics: Adult; Aged; Breast Neoplasms; Bronchial Neoplasms; Female; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Neoplasm Metastasis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Testicular Neoplasms	1967
[Internal treatment of carcinoma with the cytostatic Proresid]. Munchener medizinische Wochenschrift (1950), 1966, Jan-14, Volume: 108, Issue:2 Topics: Antineoplastic Agents; Breast Neoplasms; Female; Humans; Infusions, Parenteral; Kidney Neoplasms; Lymphoma, Large B-Cell, Diffuse; Middle Aged; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Peritonitis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Pleural Neoplasms; Pleurisy; Podophyllum; Stomach Neoplasms; Uterine Neoplasms	1966
[Combination treatment of pulmonary metastasis using radiotherapy and chemotherapy]. Strahlentherapie, 1969, Volume: 137, Issue:6 Topics: Adenocarcinoma; Adult; Breast Neoplasms; Cobalt Isotopes; Female; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Radioisotope Teletherapy; Thyroid Neoplasms	1969
[Comparative results of massive endoxan stoss therapy and treatment of malignant tumors with proresid]. Die Medizinische Welt, 1967, Jul-29, Volume: 30 Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide; Humans; Injections, Intravenous; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum	1967
[Plasma iron turnover before and following cytostatic therapy and its signifiance as indicator of tumor activity]. Klinische Wochenschrift, 1968, Dec-01, Volume: 46, Issue:23 Topics: Antineoplastic Agents; Breast Neoplasms; Female; Follow-Up Studies; Humans; Iron; Iron Isotopes; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Prostatic Neoplasms; Rectal Neoplasms; Thyroid Neoplasms; Time Factors; Urinary Bladder Neoplasms	1968
[On diagnostic and therapeutic problems of the metastasizing breast carcinoma]. Der Krebsarzt, 1969, Volume: 24, Issue:3 Topics: Adult; Aged; Austria; Breast Neoplasms; Diagnosis, Differential; Gold Colloid, Radioactive; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Plants, Medicinal; Plants, Toxic; Pleural Effusion; Pleural Neoplasms; Podophyllin; Podophyllum	1969