Page last updated: 2024-08-21

podophyllotoxin and Bone Cancer

podophyllotoxin has been researched along with Bone Cancer in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahn, SC; Ji, JH; Kim, KY; Kim, SH; Kim, YW; Nam, HW; Park, SG; Son, KM; Suh, JT; Yu, SN1
Gao, JJ; Miao, SW; Wang, BJ; Wu, YT1
Wan, Y1
Choy, E; Duan, Z; Harmon, D; Hornicek, FJ; Mankin, H; Ryu, K; Schwab, J; Yang, C1
Axelson, M; Coulton, L; Croucher, P; De Leenheer, E; De Raeve, H; Gallagher, O; Jernberg-Wiklund, H; Larsson, O; Menu, E; Nilsson, K; Van Camp, B; Van Valckenborgh, E; Vanderkerken, K1
Chen, CR; Guo, SF; Li, WG; Yang, TM; Zhang, XY1
Campbell, AM; Ekert, H; Waters, KD1
Bonnet, F; Cany, L; Coindre, JM; de Mascarel, A; Robert, J; Vergier, B1
Cavalli, F; D'Incalci, M; De Fusco, M; de Jong, J; Hanauske, A; Kaeser-Fröhlich, A; Pagani, O; Sessa, C; Zucchetti, M1
Arkles, B; Cosolo, W; Morstyn, G; Zalcberg, JR; Zimet, AS1
Hino, M; Kawano, Y; Komi, N; Koyama, T; Mahbubul Huq, AH; Ninomiya, T; Sato, J; Takaue, Y; Takehara, H; Watanabe, T1

Reviews

1 review(s) available for podophyllotoxin and Bone Cancer

ArticleYear
New Mechanism of Bone Cancer Pain: Tumor Tissue-Derived Endogenous Formaldehyde Induced Bone Cancer Pain via TRPV1 Activation.
    Advances in experimental medicine and biology, 2016, Volume: 904

    Topics: Animals; Bone Neoplasms; Cancer Pain; Capsaicin; Cells, Cultured; Formaldehyde; Glycine Hydroxymethyltransferase; Histone Demethylases; Humans; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Neoplasm Proteins; Osteoblasts; Peripheral Nerves; Podophyllotoxin; Protein Kinase Inhibitors; Signal Transduction; TRPV Cation Channels

2016

Trials

2 trial(s) available for podophyllotoxin and Bone Cancer

ArticleYear
VM-26 and dimethyl triazeno imidazole carboxamide in Ewing's sarcoma.
    Australian paediatric journal, 1983, Volume: 19, Issue:1

    Topics: Adolescent; Bone Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Dacarbazine; Doxorubicin; Drug Therapy, Combination; Female; Humans; Male; Podophyllotoxin; Random Allocation; Sarcoma, Ewing; Teniposide; Vincristine

1983
Clinical and pharmacokinetic study of oral NK611, a new podophyllotoxin derivative.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:6

    Topics: Administration, Oral; Adrenal Gland Neoplasms; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biological Availability; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasms; Neutropenia; Podophyllotoxin; Thrombocytopenia

1996

Other Studies

8 other study(ies) available for podophyllotoxin and Bone Cancer

ArticleYear
Deoxypodophyllotoxin induces cytoprotective autophagy against apoptosis via inhibition of PI3K/AKT/mTOR pathway in osteosarcoma U2OS cells.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drugs, Chinese Herbal; Gene Expression Regulation; Humans; Osteosarcoma; Phosphoinositide-3 Kinase Inhibitors; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; TOR Serine-Threonine Kinases

2017
Picropodophyllin inhibits the growth of Ewing's sarcoma cells through the insulin‑like growth factor‑1 receptor/Akt signaling pathway.
    Molecular medicine reports, 2015, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Sarcoma, Ewing; Signal Transduction

2015
Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Osteosarcoma; Podophyllotoxin; Protein Kinase Inhibitors; Receptor, IGF Type 1; RNA, Small Interfering

2009
Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival.
    International journal of cancer, 2007, Oct-15, Volume: 121, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Bone Neoplasms; Disease Models, Animal; Kaplan-Meier Estimate; Mice; Multiple Myeloma; Neovascularization, Pathologic; Podophyllotoxin; Receptor, IGF Type 1

2007
Anti-osteosarcoma effects and mechanisms of 4-O-amino-phenol-4'-demethylepipodophyllotoxin ether.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Calcium; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ethers; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Magnesium; Membrane Potential, Mitochondrial; Osteosarcoma; Podophyllotoxin; Reactive Oxygen Species; Time Factors

2008
Expression of MDR1/P glycoprotein in human sarcomas.
    British journal of cancer, 1993, Volume: 68, Issue:6

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Neoplasms; Carrier Proteins; Dactinomycin; Drug Resistance; Gene Expression; Hemangiosarcoma; Histiocytoma, Benign Fibrous; Histocytochemistry; Humans; Immunoblotting; In Situ Hybridization; Leiomyosarcoma; Liposarcoma; Membrane Glycoproteins; Neoplasm Proteins; Podophyllotoxin; Rhabdomyosarcoma; RNA, Messenger; RNA, Neoplasm; Sarcoma; Sarcoma, Ewing; Soft Tissue Neoplasms; Tumor Cells, Cultured; Vinca Alkaloids

1993
Flare responses in small cell carcinoma of the lung.
    Clinical nuclear medicine, 1988, Volume: 13, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carboplatin; Carcinoma, Small Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Podophyllotoxin; Radionuclide Imaging

1988
[Attempted marrow rescue with cryopreserved circulating stem cells following high-dose chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Preservation; Bone Neoplasms; Child, Preschool; Cisplatin; Freezing; Hematopoietic Stem Cell Transplantation; Humans; Leukapheresis; Male; Melphalan; Neuroblastoma; Podophyllotoxin; Transplantation, Autologous

1988