podophyllin and Vaginitis

316 women with genital warts were studied to relate treatment response to concomitant genital infection at presentation. There was a highly significant difference between the response patterns of those patients who presented with warts alone, and those presenting with other infections (most commonly candidiasis and non-specific vaginitis). The diagnosis and treatment of associated infections hastens the response of warts to cytotoxic therapy, but there appears to be a subgroup amongst women presenting with warts alone, who require a considerably longer course of treatment. The relevance of these findings to the pathogenesis and management of genital warts is discussed.

Topics: Candidiasis, Vulvovaginal; Condylomata Acuminata; Female; Gonorrhea; Humans; Podophyllin; Time Factors; Trichomonas Vaginitis; Vaginitis