podophyllin and Papilloma

A study of 37 women with typical condylomas and so-called squamous micropapilloma was undertaken to determine their response to systemic interferon and/or podophyllin treatment. Thirty lesions were classified as condylomas and 9 as squamous micropapillomas; two women had both lesions. Twenty-six (87%) of 30 condylomas responded, whereas only 1 (11%) of the 9 cases of micropapillomatosis showed a partial response (P less than .001) to podophyllin and/or interferon. Twenty-six biopsies from condylomas in which sufficient DNA was available for analysis contained human papillomavirus (HPV) DNA sequences that hybridized to an HPV 6 + 16 probe mix under nonstringent conditions. In contrast, HPV DNA sequences could not be detected in any of the nine cases of micropapillomatosis. Immunoperoxidase studies performed on these lesions failed to demonstrate viral capsid antigen. Thus, despite certain similarities in the clinical presentation and microscopic features of condylomas and squamous micropapillomas, it is not clear at present whether micropapillomas are HPV-related lesions.

Topics: Condylomata Acuminata; DNA, Viral; Drug Therapy, Combination; Female; Humans; Interferon Type I; Neoplasm Recurrence, Local; Papilloma; Papillomaviridae; Podophyllin; Vulvar Neoplasms

Topics: Administration, Topical; Adult; Antineoplastic Agents, Phytogenic; Corneal Diseases; Eye Pain; Eyelid Neoplasms; Glucocorticoids; Humans; Male; Papilloma; Photophobia; Podophyllin; Prednisolone; Vision Disorders; Visual Acuity

We have described a 20-year-old man with recurrent intranasal papillomas that were successfully treated by twice-weekly applications of 25% podophyllin in tincture of benzoin.

Topics: Adult; Humans; Male; Neoplasm Recurrence, Local; Nose Neoplasms; Papilloma; Podophyllin

Topics: Aluminum; Burns, Chemical; Circumcision, Male; Colchicine; Condylomata Acuminata; Female; Humans; Male; Mucous Membrane; Papilloma; Penile Diseases; Plants, Medicinal; Podophyllin; Syndrome; Urethral Diseases

Topics: Female; Humans; Metronidazole; Papilloma; Podophyllin; Trichomonas Vaginitis; Vaginal Neoplasms; Vulvar Neoplasms

Topics: Condylomata Acuminata; Humans; Papilloma; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Virus Diseases

Topics: Condylomata Acuminata; Female; Humans; Hygiene; Male; Papilloma; Podophyllin; Virus Diseases

Topics: Adult; Arthritis, Infectious; Condylomata Acuminata; Cystoscopy; Female; Humans; Kidney; Nephrectomy; Papilloma; Podophyllin; Ureteral Neoplasms; Urinary Bladder; Urinary Bladder Neoplasms; Urography; Virus Diseases; Vulvar Neoplasms

Topics: Adult; Condylomata Acuminata; Female; Humans; Male; Papilloma; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Virus Diseases

Topics: Condylomata Acuminata; Female; Humans; Papilloma; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Pregnancy; Pregnancy Complications; Virus Diseases; Vulva

Topics: Antineoplastic Agents; Humans; Laryngeal Neoplasms; Laryngoscopy; Papilloma; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum

Topics: Adult; Alcoholic Beverages; Anal Canal; Condylomata Acuminata; Drug Synergism; Ethanol; Female; Humans; Male; Papilloma; Penis; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Virus Diseases

Topics: Buschke-Lowenstein Tumor; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Genitalia, Male; Humans; Lymphatic Metastasis; Male; Neoplasms; Papilloma; Pathology; Penile Neoplasms; Podophyllin; Podophyllum; Scrotum; Skin Neoplasms; Surgical Procedures, Operative

Topics: Cautery; Diagnosis; Drug Therapy; Humans; Male; Papilloma; Pathology; Podophyllin; Podophyllum; Sexually Transmitted Diseases; Toxicology; Urethra

Topics: Fibroma; Laryngeal Neoplasms; Larynx; Papilloma; Podophyllin; Podophyllum; Tissue Culture Techniques

Topics: Papilloma; Podophyllin; Podophyllum; Urinary Bladder Neoplasms

Topics: Humans; Papilloma; Podophyllin; Podophyllum; Warts

Topics: Humans; Keloid; Laryngeal Neoplasms; Larynx; Papilloma; Papillomavirus Infections; Podophyllin; Podophyllum; Precancerous Conditions

Topics: Carcinoma; Carcinoma, Papillary; Humans; Papilloma; Podophyllin; Podophyllum; Urinary Bladder Neoplasms

Topics: Child; Fibroma; Glycols; Humans; Infant; Laryngeal Neoplasms; Larynx; Papilloma; Podophyllin; Polyethylene Glycols

Topics: Humans; Papilloma; Podophyllin; Urinary Bladder Neoplasms

Topics: Condylomata Acuminata; Female; Humans; Papilloma; Podophyllin; Pregnancy; Pregnancy Complications; Vulvar Neoplasms

Topics: Humans; Papilloma; Podophyllin; Urinary Bladder Neoplasms

Topics: Humans; Papilloma; Podophyllin; Urinary Bladder Neoplasms

Topics: Humans; Papilloma; Podophyllin; Urinary Bladder Neoplasms

Topics: Humans; Neoplasms; Papilloma; Podophyllin

Topics: Adolescent; Humans; Larynx; Neoplasms; Papilloma; Podophyllin; Podophyllum; Resins, Plant

Topics: Abdominal Cavity; Humans; Papilloma; Podophyllin; Urinary Bladder Neoplasms

Topics: Female; Humans; Male; Neoplasms; Papilloma; Podophyllin; Skin Neoplasms; Urethra; Vulva