podophyllin and Anus-Neoplasms
podophyllin has been researched along with Anus-Neoplasms* in 14 studies
Reviews
1 review(s) available for podophyllin and Anus-Neoplasms
Article | Year |
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Condylomata acuminata (anogenital warts).
Topics: Adolescent; Adult; Age Factors; Anus Neoplasms; Child; Condylomata Acuminata; Cryosurgery; Dichloroacetic Acid; Electrosurgery; Female; Genital Neoplasms, Female; Humans; Infant, Newborn; Male; Podophyllin; Pregnancy; Pregnancy Complications, Neoplastic; Recurrence; Sex Factors; Sexually Transmitted Diseases; Trichloroacetic Acid | 1985 |
Trials
3 trial(s) available for podophyllin and Anus-Neoplasms
Article | Year |
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Podophyllin versus scissor excision in the treatment of perianal condylomata acuminata: a prospective study.
Thirty-seven patients with previously untreated perianal condylomata acuminata were randomly treated by application of 25 per cent podophyllin or scissor excision. The result of treatment was assessed by an independent observer. At 6 weeks, scissor excision completely cleared the warts from 16 of 18 patients (89 per cent) compared with 15 of 19 patients (79 per cent) treated with podophyllin. Following complete clearance by surgery, two patients had recurrent warts at 18 weeks and a further single patient at 42 weeks, giving a cumulative recurrence rate of 19 per cent. In contrast, five of 15 patients whose warts were cleared by podophyllin had recurrent warts at 18 weeks and a further four at 42 weeks representing a cumulative recurrence rate of 60 per cent (X2 = 3.95, d.f. = 1, P = 0.05). At 42 weeks six patients (32 per cent) were free of disease in the podophyllin group compared with 13 (72 per cent) in the scissor excision group (X2 = 4.6, d.f. = 1, P = 0.03). Scissor excision is therefore preferable to podophyllin application in the treatment of perianal condylomata acuminata. Topics: Adult; Anal Canal; Anus Neoplasms; Condylomata Acuminata; Female; Genital Neoplasms, Female; Genital Neoplasms, Male; Genitalia; Humans; Male; Middle Aged; Podophyllin; Prospective Studies; Random Allocation | 1989 |
Treatment of condyloma acuminatum.
Topics: Adult; Anal Canal; Anus Neoplasms; Condylomata Acuminata; Female; Humans; Male; Middle Aged; Podophyllin; Recurrence | 1986 |
Comparison of podophyllin application with simple surgical excision in clearance and recurrence of perianal condylomata acuminata.
60 patients with first-episode perianal condylomata acuminata were randomly assigned to podophyllin application or surgical excision. 58% of the male patients were homosexual and 33% of the female patients regularly had anal intercourse. Podophyllin completely cleared warts from 23 of 30 (76.6%) patients compared with 28 of 30 (93.3%) for surgical excision. After wart clearance the cumulative recurrence rates were 18% for surgical excision and 43% for podophyllin at 3 months (p less than 0.05), 22% and 56% at 6 months (p less than 0.01), 26% and 56% at 9 months (p less than 0.01), and 29% and 65% at 12 months (p less than 0.01). All patients were treated as outpatients and all surgical procedures were carried out under local anaesthesia. Both regimens were well tolerated. Topics: Adolescent; Adult; Anus Neoplasms; Clinical Trials as Topic; Condylomata Acuminata; Female; Humans; Male; Neoplasm Recurrence, Local; Podophyllin; Prospective Studies; Random Allocation | 1985 |
Other Studies
10 other study(ies) available for podophyllin and Anus-Neoplasms
Article | Year |
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Giant anal condyloma (giant condyloma acuminatum of anus) after allogeneic bone marrow transplantation associated with human papillomavirus: a case report.
Condyloma acuminatum are caused by human papillomavirus. Giant condyloma acuminatum is a locally invasive, destructive, and large sized mass. Risk factors for the development of giant condyloma acuminatum include an immunodeficient state, such as human immunodeficiency virus infection, post-organ transplantation, or post-allogeneic bone marrow transplantation. However, reports of giant condyloma after bone marrow transplantation are extremely rare (0.3 to 1.3%). The standard treatment for giant condyloma acuminatum is recommended as wide surgical resection due to its high rate of success and low rate of recurrence.. A 31-year-old Korean man presented to our hospital with anal discomfort for more than one month due to a protruding mass. He had a history of BCR-ABL-positive acute lymphoblastic leukemia and had undergone an allogenic stem cell transplantation. Gross findings revealed a large perianal cauliflower-like mass over 7cm in size with invasion of the anal orifice. He was diagnosed with giant anal condyloma occurring after an allogeneic bone marrow transplantation. However, we achieved successful treatment using a combination of topical podophyllin and cryotherapy and transanal surgical excision, followed by bleomycin irrigation.. We report an extremely rare case of giant condyloma acuminatum of anus due to human papillomavirus type six in a patient with acute lymphoblastic leukemia following an allogeneic bone marrow transplantation. The tumor was successfully treated with a combination of topical podophyllin and cryotherapy and transanal surgical excision, followed by bleomycin irrigation. Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Anus Neoplasms; Bleomycin; Bone Marrow Transplantation; Condylomata Acuminata; Cryotherapy; Human papillomavirus 6; Humans; Male; Papillomavirus Infections; Podophyllin; Transplantation, Homologous; Treatment Outcome | 2015 |
[Malignant transformation of perianal condyloma acuminatum].
A case of squamous cell carcinoma developing in a perianal condyloma acuminatum in a 38-year-old man treated for over 5 years with podophyllin is presented. Although there are many reports of malignant transformation of condyloma acuminatum in the skin and mucosal surfaces of the male and female genitalia, it is quite rare in the perianal region. In this case there were foci of carcinoma in-situ and of frank invasion, as well as areas of squamous cell carcinoma in the large perianal condyloma. The lesion was widely excised, and completely removed, and the site covered with a split-thickness graft from the thigh. Later, repeated dilatations of the anus were required. Repeated histologic examinations of condyloma acuminatum are needed to diagnose possible malignant transformation. Topics: Adult; Animals; Anus Neoplasms; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Condylomata Acuminata; Humans; Male; Podophyllin | 1991 |
[Treatment of anogenital warts].
Topics: Adult; Anus Neoplasms; Condylomata Acuminata; Cryosurgery; Female; Genital Neoplasms, Female; Genital Neoplasms, Male; Humans; Male; Podophyllin | 1984 |
[Condyloma acuminatum in infancy and childhood].
Topics: Anus Neoplasms; Child; Condylomata Acuminata; Electrocoagulation; Genital Neoplasms, Male; Humans; Infant; Laryngeal Neoplasms; Male; Podophyllin; Vocal Cords | 1983 |
Giant and recurrent condyloma acuminatum: appraisal of immunotherapy.
Eighty-four cases of condyloma acuminatum were presented, with conventional treatment, e.g., surgical excision and fulguration with or without Podophyllin application. Recurrence rate was 28 per cent to 65 per cent, depending on the number and duration of treatments. Immunotherapy was used on 17 patients with recurrent and giant condyloma acuminatum. Condylomata were successfully eradicated in 94.1 per cent of patients, which indicates that immunotherapy is a very effective alternative in the treatment of recurrent and giant condyloma acuminatum. Topics: Adolescent; Adult; Anus Neoplasms; Child; Child, Preschool; Condylomata Acuminata; Electric Stimulation Therapy; Female; Humans; Immunotherapy; Infant; Male; Middle Aged; Neoplasm Recurrence, Local; Podophyllin | 1982 |
Anal eroticism.
A delineation of the medical problems associated with anal sexual eroticism has been presented. Our method of approach to both the patient and the various disease states has been described. Treatment of the most commonly encountered condition, condyloma acuminata, has been detailed. Precautionary measures to be taken and possible diagnostic pitfalls have been mentioned. Topics: Anal Canal; Anus Diseases; Anus Neoplasms; Condylomata Acuminata; Enterobacteriaceae; Female; Foreign Bodies; Gonorrhea; Humans; Male; Podophyllin; Rectal Diseases; Sexual Behavior; Syndrome; Syphilis; Ulcer; Urinary Fistula; Warts | 1978 |
[Podophyllin solution in perianal condylomata acuminata in infants].
Topics: Anus Neoplasms; Child, Preschool; Condylomata Acuminata; Humans; Male; Podophyllin | 1977 |
Management of warts.
Topics: Anus Neoplasms; Condylomata Acuminata; Formaldehyde; Genitalia; Humans; Immunotherapy; Nitrogen; Podophyllin; Salicylates; Skin Diseases, Infectious; Warts | 1976 |
The variable significance of condylomata acuminata.
Topics: Adult; Anus Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cautery; Condylomata Acuminata; Female; Humans; Male; Middle Aged; Podophyllin; Precancerous Conditions | 1974 |
Treatment of extensive condyloma acuminata of the anal canal.
Topics: Adult; Anus Neoplasms; Chronic Disease; Condylomata Acuminata; Electrosurgery; Follow-Up Studies; Homosexuality; Humans; Male; Podophyllin; Recurrence | 1973 |