plx4032 and Cardiomegaly

plx4032 has been researched along with Cardiomegaly* in 1 studies

Other Studies

1 other study(ies) available for plx4032 and Cardiomegaly

Article	Year
Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors. Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13 A series of N-(3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides were designed as the first class of highly selective ZAK inhibitors. The representative compound 3h strongly inhibits the kinase activity of ZAK with an IC Topics: Animals; Benzenesulfonamides; Cardiomegaly; Drug Design; Humans; MAP Kinase Kinase Kinases; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Kinases; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides	2017

Article

Year

Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

A series of N-(3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides were designed as the first class of highly selective ZAK inhibitors. The representative compound 3h strongly inhibits the kinase activity of ZAK with an IC

Topics: Animals; Benzenesulfonamides; Cardiomegaly; Drug Design; Humans; MAP Kinase Kinase Kinases; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Kinases; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides

2017