plumbagin has been researched along with Pancreatic Neoplasms in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Krishnamoorthi, S; Murugantham, B; Muthusami, S; Periyasamy, L; Sundaraj, R | 1 |
| Murugantham, B; Muthusami, S; Periyasamy, L | 1 |
| Biswal, BK; Panda, M; Pandey, K; Tripathi, SK | 1 |
| Li, R; Pan, Q; Su, M; Zhou, R | 1 |
| He, ZX; Li, M; Pan, ST; Qiu, JX; Sun, T; Wang, D; Wang, F; Wang, Q; Yang, T; Yang, YX; Yu, SN; Zhang, X; Zhou, SF; Zhou, ZW | 1 |
| Chang, HH; Chen, CA; Chen, YJ; Kao, CY; Tsai, TH | 1 |
| Fischer, JW; Hafeez, BB; Jamal, MS; Mustafa, A; Verma, AK | 1 |
7 other study(ies) available for plumbagin and Pancreatic Neoplasms
| Article | Year |
|---|---|
Screening of MMP-2 Inhibiting Phytoconstituents for the Development of Newer Pancreatic Cancer Treatment Modalities.
Topics: Cell Line, Tumor; Early Detection of Cancer; Emodin; Humans; Matrix Metalloproteinase 2; Molecular Docking Simulation; Pancreatic Neoplasms | 2023 |
Plumbagin binds to epidermal growth factor receptor and mitigate the effects of epidermal growth factor micro-environment in PANC-1 cells.
Topics: Cell Line, Tumor; Epidermal Growth Factor; ErbB Receptors; Humans; Naphthoquinones; Pancreatic Neoplasms | 2023 |
Prooxidative activity of plumbagin induces apoptosis in human pancreatic ductal adenocarcinoma cells via intrinsic apoptotic pathway.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; DNA Damage; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidative Stress; Pancreatic Neoplasms; Reactive Oxygen Species; Signal Transduction | 2020 |
The Effects of Plumbagin on Pancreatic Cancer: A Mechanistic Network Pharmacology Approach.
Topics: Biomarkers, Tumor; Computational Biology; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Gene Regulatory Networks; Humans; Naphthoquinones; Pancreatic Neoplasms; Protein Interaction Maps; Signal Transduction | 2019 |
Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autophagy; Cell Cycle Checkpoints; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial-Mesenchymal Transition; Humans; Naphthoquinones; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phenotype; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases | 2015 |
Plumbagin, isolated from Plumbago zeylanica, induces cell death through apoptosis in human pancreatic cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Caspases; Cell Line, Tumor; Cell Proliferation; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Naphthoquinones; Pancreatic Neoplasms; Plumbaginaceae; Xenograft Model Antitumor Assays | 2009 |
Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin D1; ErbB Receptors; Humans; Inhibitor of Apoptosis Proteins; Male; Matrix Metalloproteinase Inhibitors; Mice; Mice, SCID; Naphthoquinones; NF-kappa B; Pancreatic Neoplasms; Phosphorylation; Plant Extracts; Signal Transduction; STAT3 Transcription Factor; Survivin | 2012 |