Page last updated: 2024-08-21

plumbagin and Neoplasms

plumbagin has been researched along with Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Janathia, B; Thakor, N1
Ahmad, I; Alam, SSM; Hoque, M; Tabrez, S; Zughaibi, TA1
Roy, A1
Chen, L; Guo, Q; Kang, W; Yang, B; Yin, Z; Zhang, J; Zhang, W1
Cai, Y; Chen, M; He, C; Li, H; Liu, Y1
Biswal, BK; Panda, M; Tripathi, SK1
Binoy, A; Bose, C; Katiyar, N; Mishra, N; Nair, BG; Nedungadi, D; Shankarappa, SA1
Cai, W; Liu, X; Niu, M; Xu, K; Xu, X; Yu, R; Zeng, L; Zhou, X1
Tuorkey, MJ1
Ahmad, A; Azmi, AS; Hadi, SM; Hanif, S; Kumar, KS; Mohammad, RM; Nazeem, S1
Chen, Y; Dong, Y; He, L; Lai, L; Lin, Q; Liu, J; Liu, M; Lu, B; Yi, Z; Zhai, D; Zhang, J1
Bao, JL; Chen, XP; Huang, MQ; Lu, JJ; Wang, YT; Wu, GS; Xu, WS1

Reviews

7 review(s) available for plumbagin and Neoplasms

ArticleYear
Plumbagin: A Potential Candidate for Future Research and Development.
    Current pharmaceutical biotechnology, 2022, Volume: 23, Issue:15

    Topics: Animals; Humans; Naphthoquinones; Neoplasms; Plumbaginaceae; Research

2022
Plumbagin: A Potential Anti-cancer Compound.
    Mini reviews in medicinal chemistry, 2021, Volume: 21, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Humans; Naphthoquinones; Neoplasms; NF-kappa B; Plumbaginaceae; Signal Transduction

2021
Anticancer Effects and Mechanisms of Action of Plumbagin: Review of Research Advances.
    BioMed research international, 2020, Volume: 2020

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Damage; Drug Screening Assays, Antitumor; Glutathione; Humans; Inhibitory Concentration 50; Liposomes; Mice; Mice, Inbred C57BL; Naphthoquinones; Neoplasm Metastasis; Neoplasms; Oxidants; Oxygen; Plant Extracts; Plants, Medicinal; Proteasome Inhibitors; Reactive Oxygen Species; Superoxides

2020
Anticancer Properties and Pharmaceutical Applications of Plumbagin: A Review.
    The American journal of Chinese medicine, 2017, Volume: 45, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Droseraceae; Ebenaceae; Genes, ras; Humans; In Vitro Techniques; Mice; Naphthoquinones; Neoplasms; Phosphatidylinositol 3-Kinase; Phytotherapy; Plumbaginaceae; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2017
Emerging role of plumbagin: Cytotoxic potential and pharmaceutical relevance towards cancer therapy.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 125

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; Male; Naphthoquinones; Neoplasms; Reactive Oxygen Species; Signal Transduction

2019
Cancer Therapy with Phytochemicals: Present and Future Perspectives.
    Biomedical and environmental sciences : BES, 2015, Volume: 28, Issue:11

    Topics: Acetophenones; Antineoplastic Agents, Phytogenic; Benzopyrans; Benzylisoquinolines; Catechols; Heterocyclic Compounds, 4 or More Rings; Humans; Isothiocyanates; Naphthoquinones; Neoplasms; Phytotherapy; Plant Extracts; Signal Transduction; Sulfoxides

2015
Quinones derived from plant secondary metabolites as anti-cancer agents.
    Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:3

    Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Line, Tumor; Cell Survival; Humans; Naphthoquinones; Neoplasms; Plant Extracts

2013

Other Studies

5 other study(ies) available for plumbagin and Neoplasms

ArticleYear
Curcumin and Plumbagin Synergistically Target the PI3K/Akt/mTOR Pathway: A Prospective Role in Cancer Treatment.
    International journal of molecular sciences, 2023, Apr-02, Volume: 24, Issue:7

    Topics: Curcumin; Humans; Molecular Docking Simulation; Neoplasms; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2023
Plumbagin induces paraptosis in cancer cells by disrupting the sulfhydryl homeostasis and proteasomal function.
    Chemico-biological interactions, 2019, Sep-01, Volume: 310

    Topics: Cell Death; Cell Line; Cell Line, Tumor; Endoplasmic Reticulum Stress; Homeostasis; Humans; Membrane Potential, Mitochondrial; Naphthoquinones; Neoplasms; Proteasome Inhibitors; Sulfhydryl Compounds; Vacuoles

2019
CRM1 is a direct cellular target of the natural anti-cancer agent plumbagin.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:4

    Topics: Cell Line, Tumor; Cell Nucleus; Drug Design; Exportin 1 Protein; Humans; Karyopherins; Molecular Targeted Therapy; Naphthoquinones; Neoplasms; Nuclear Proteins; Phytotherapy; Plumbaginaceae; Protein Transport; Receptors, Cytoplasmic and Nuclear; Tumor Suppressor Proteins

2014
Plumbagin induces cell death through a copper-redox cycle mechanism in human cancer cells.
    Mutagenesis, 2009, Volume: 24, Issue:5

    Topics: Cell Death; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Shape; Comet Assay; Copper; Cytoprotection; Free Radical Scavengers; Humans; Naphthoquinones; Neoplasms; Oxidation-Reduction; Phenanthrolines; Skin Neoplasms

2009
Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor-2.
    British journal of pharmacology, 2012, Volume: 165, Issue:4b

    Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chickens; Chorioallantoic Membrane; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Naphthoquinones; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; ras Proteins; Signal Transduction; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2012