Page last updated: 2024-08-21

plumbagin and Lung Neoplasms

plumbagin has been researched along with Lung Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (72.73)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Im, E; Kang, CG; Lee, EO; Lee, HJ1
Guo, J; Ma, K; Ma, Q; Sun, S; Xu, J; Xu, W; Yang, R; Yang, Y; Zhang, J; Zhang, Y1
Basu, B; Checker, R; Pal, D; Patwardhan, RS; Sandur, SK; Sharma, D1
Biswal, BK; Rengasamy, KRR; Tripathi, SK1
Fan, XX; Huang, JM; Jiang, ZB; Leung, EL; Ma, YP; Wang, QQ; Wang, W; Wang, XR; Wu, QB; Xie, C; Xie, YJ; Xu, C; Yan, PY; Yao, XJ; Zhang, YZ1
Li, KY; Liu, G; Shao, Y; Xu, YY; Yu, T; Zhang, YY1
Liu, LX; Shen, H; Shu, YQ; Xu, TP1
Itharat, A; Pawa, KK; Rattarom, R; Ruangnoo, S; Sakpakdeejaroen, I; Tappayutpijam, P1
Chow, K; Duan, W; He, SM; He, ZX; Huang, GH; Li, M; Li, YC; Liu, A; Liu, JP; Pang, JX; Qiu, JX; Yang, T; Yang, Y; Zhang, X; Zhou, Q; Zhou, SF; Zhou, ZW1
Hansakul, P; Itharat, A; Rattarom, R; Sakpakdeejaroen, I1
Chang, WT; Chao, CH; Chiang, TA; Huang, GY; Lee, YC; Shieh, JM; Shih, YW; Shih, YX1

Other Studies

11 other study(ies) available for plumbagin and Lung Neoplasms

ArticleYear
Plumbagin reduces osteopontin-induced invasion through inhibiting the Rho-associated kinase signaling pathway in A549 cells and suppresses osteopontin-induced lung metastasis in BalB/c mice.
    Bioorganic & medicinal chemistry letters, 2017, 05-01, Volume: 27, Issue:9

    Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Movement; Humans; Lung; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Neoplasm Invasiveness; Osteopontin; Plumbaginaceae; Protein Kinase Inhibitors; rho-Associated Kinases; Signal Transduction

2017
Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 146

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Glucose Transporter Type 1; Humans; Kelch-Like ECH-Associated Protein 1; Lung Neoplasms; Naphthoquinones; NF-E2-Related Factor 2; Pyrazoles; Quinolines; Rats; Reactive Oxygen Species; Selenocysteine; Thioredoxin Reductase 1

2022
Modulation of Caspase-3 activity using a redox active vitamin K3 analogue, plumbagin, as a novel strategy for radioprotection.
    Free radical biology & medicine, 2019, 11-01, Volume: 143

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Proliferation; Gamma Rays; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Lymphocytes; Mice; Naphthoquinones; Oxidation-Reduction; Phosphorylation; Radiation-Protective Agents

2019
Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction.
    Archives of pharmacal research, 2020, Volume: 43, Issue:2

    Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 9; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Molecular Structure; Naphthoquinones; Reactive Oxygen Species; Structure-Activity Relationship; Tumor Cells, Cultured

2020
Plumbagin suppresses non-small cell lung cancer progression through downregulating ARF1 and by elevating CD8
    Pharmacological research, 2021, Volume: 169

    Topics: ADP-Ribosylation Factor 1; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Down-Regulation; Female; Lung Neoplasms; Lymphocyte Activation; Mice, Nude; Naphthoquinones; Neoplasm Transplantation

2021
Plumbagin suppresses the human large cell lung cancer cell lines by inhibiting IL-6/STAT3 signaling in vitro.
    International immunopharmacology, 2018, Volume: 55

    Topics: Antineoplastic Agents; Carcinoma, Large Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Interleukin-6; Lung Neoplasms; Naphthoquinones; Phosphorylation; Signal Transduction; STAT3 Transcription Factor

2018
Plumbagin from Plumbago Zeylanica L induces apoptosis in human non-small cell lung cancer cell lines through NF- κB inactivation.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:4

    Topics: Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Electrophoretic Mobility Shift Assay; Humans; Luciferases; Lung Neoplasms; Naphthoquinones; NF-kappa B; Plumbaginaceae; Protein Transport; Superoxides; Tumor Cells, Cultured

2013
In vitro cytotoxic activity of Benjakul herbal preparation and its active compounds against human lung, cervical and liver cancer cells.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2012, Volume: 95 Suppl 1

    Topics: Alkaloids; Benzodioxoles; Catechols; Cell Line, Tumor; Fatty Alcohols; Female; Humans; Liver Neoplasms; Lung Neoplasms; Medicine, East Asian Traditional; Naphthoquinones; Phytotherapy; Piper; Piperidines; Plant Extracts; Plants, Medicinal; Plumbaginaceae; Polyunsaturated Alkamides; Thailand; Uterine Cervical Neoplasms; Zingiber officinale

2012
Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells.
    Cancer letters, 2014, Mar-28, Volume: 344, Issue:2

    Topics: Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Lung Neoplasms; MAP Kinase Signaling System; Naphthoquinones; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2014
Cytotoxic activity against small cell lung cancer cell line and chromatographic fingerprinting of six isolated compounds from the ethanolic extract of Benjakul.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2014, Volume: 97 Suppl 8

    Topics: Alkaloids; Benzodioxoles; Catechols; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Ethanol; Fatty Alcohols; Humans; Lung Neoplasms; Medicine, Traditional; Naphthoquinones; Piper; Piperidines; Plant Extracts; Plumbaginaceae; Polyunsaturated Alkamides; Small Cell Lung Carcinoma; Thailand; Zingiber officinale

2014
Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells.
    Molecular and cellular biochemistry, 2010, Volume: 335, Issue:1-2

    Topics: Cell Line, Tumor; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinase 3; Naphthoquinones; NF-kappa B; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Urokinase-Type Plasminogen Activator

2010