Page last updated: 2024-08-21

plumbagin and Inflammation

plumbagin has been researched along with Inflammation in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's11 (78.57)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Ashma, R; Bagade, MM; Ghumnani, S; Kubatzky, KF; Raman, S; Saha, B; Yadav, AM1
Liang, D; Liu, L; Zhang, L1
Areti, A; Arruri, V; Dungavath, SKN; Komirishetty, P; Kumar, A1
Bawankule, DU; Gupta, AC; Maurya, AK; Mohanty, S; Saxena, A1
Gaur, IS; Gursahani, MS; Juvekar, AR; Mestry, SN; Munshi, RP; Pai, SA; Panchal, FH1
Jin, Z; Tang, T; Tu, B; Wang, T; Wang, Y; Wu, F; Yan, W; Zhai, Z1
Cheng, L; Hou, Y; Nie, L; Si, M; Zhang, W; Zhao, YP1
Kawamura, M; Kuramochi, K; Kuriyama, I; Mizushina, Y; Naganune, H; Onodera, T; Sakamoto, Y; Tabata, A; Tsubaki, K1
Liang, M; Song, J; Yang, JY; Yang, W; Yang, Y1
Chu, H; Huang, H; Ren, D; Yu, H; Zhu, K1
Chen, C; Chen, H; Tao, Z; Ying, X; Zhang, C; Zhang, H; Zheng, W1
Ge, L; Liu, L; Liu, Y; Luo, P; Wong, YF; Zhang, ZF; Zhou, H1
Bothiraja, C; Dama, GY; Joshi, PP; Pawar, AP; Shaikh, KS1
Aggarwal, BB; Ahn, KS; Ichikawa, H; Sandur, SK; Sethi, G1

Reviews

1 review(s) available for plumbagin and Inflammation

ArticleYear
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts.
    Biological chemistry, 2022, 01-27, Volume: 403, Issue:2

    Topics: Bone Resorption; Cell Differentiation; Humans; Inflammation; Naphthoquinones; Osteoblasts; Osteoclasts; Phytochemicals

2022

Other Studies

13 other study(ies) available for plumbagin and Inflammation

ArticleYear
Plumbagin alleviates obesity-related asthma: Targeting inflammation, oxidative stress, and the AMPK pathway.
    Immunity, inflammation and disease, 2023, Volume: 11, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Asthma; Cytokines; Humans; Inflammation; Male; Mice; Obesity; Oxidative Stress

2023
Nrf2 and NF-κB modulation by Plumbagin attenuates functional, behavioural and biochemical deficits in rat model of neuropathic pain.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Biomarkers; Hyperalgesia; Inflammation; Male; Naphthoquinones; Neuralgia; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy

2017
Plumbagin, a vitamin K3 analogue ameliorate malaria pathogenesis by inhibiting oxidative stress and inflammation.
    Inflammopharmacology, 2018, Volume: 26, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antimalarials; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Malaria; Male; Mice; Naphthoquinones; Oxidative Stress; Plasmodium berghei; Plumbaginaceae

2018
Plumbagin reduces obesity and nonalcoholic fatty liver disease induced by fructose in rats through regulation of lipid metabolism, inflammation and oxidative stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 111

    Topics: Adjuvants, Immunologic; Animals; Antioxidants; Fructose; Inflammation; Lipid Metabolism; Male; Naphthoquinones; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Random Allocation; Rats; Rats, Wistar

2019
Plumbagin inhibits LPS-induced inflammation through the inactivation of the nuclear factor-kappa B and mitogen activated protein kinase signaling pathways in RAW 264.7 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 64

    Topics: Animals; Base Sequence; Cell Line; DNA Primers; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Naphthoquinones; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Tumor Necrosis Factor-alpha

2014
Plumbagin Protects Against Spinal Cord Injury-induced Oxidative Stress and Inflammation in Wistar Rats through Nrf-2 Upregulation.
    Drug research, 2015, Volume: 65, Issue:9

    Topics: Animals; Antioxidants; Inflammation; Male; Naphthoquinones; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Protective Agents; Rats; Spinal Cord Injuries; Up-Regulation

2015
5-O-Acyl plumbagins inhibit DNA polymerase activity and suppress the inflammatory response.
    Archives of biochemistry and biophysics, 2015, May-01, Volume: 573

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; DNA Polymerase beta; Escherichia coli Proteins; Fatty Acids; Gene Knockdown Techniques; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Naphthoquinones; Plant Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2015
Treatment with bone marrow mesenchymal stem cells combined with plumbagin alleviates spinal cord injury by affecting oxidative stress, inflammation, apoptotis and the activation of the Nrf2 pathway.
    International journal of molecular medicine, 2016, Volume: 37, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Inflammation; Locomotion; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Naphthoquinones; NF-E2-Related Factor 2; Oxidative Stress; Plumbaginaceae; Rats, Sprague-Dawley; Recovery of Function; Signal Transduction; Spinal Cord Injuries

2016
Plumbagin exerts protective effects in nucleus pulposus cells by attenuating hydrogen peroxide-induced oxidative stress, inflammation and apoptosis through NF-κB and Nrf-2.
    International journal of molecular medicine, 2016, Volume: 37, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Catalase; Chondrocytes; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Inflammation; Male; Naphthoquinones; NF-E2-Related Factor 2; NF-kappa B; Nucleus Pulposus; Osteoblasts; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase

2016
Plumbagin Prevents IL-1β-Induced Inflammatory Response in Human Osteoarthritis Chondrocytes and Prevents the Progression of Osteoarthritis in Mice.
    Inflammation, 2017, Volume: 40, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Chondrocytes; Disease Progression; Humans; Inflammation; Interleukin-1beta; Mice; Naphthoquinones; NF-kappa B; Osteoarthritis; Signal Transduction

2017
Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-κB activation.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Carrageenan; Cyclooxygenase 2; Dinoprostone; Edema; Foot; Gene Expression; Histamine; Hot Temperature; I-kappa B Proteins; Inflammation; Interleukin-1beta; Interleukin-6; Magnesium Sulfate; Male; Mice; Mice, Inbred ICR; Naphthoquinones; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Pain Threshold; Phosphorylation; Rats; Rats, Sprague-Dawley; Serotonin; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2010
Novel solvent-free gelucire extract of Plumbago zeylanica using non-everted rat intestinal sac method for improved therapeutic efficacy of plumbagin.
    Journal of pharmacological and toxicological methods, 2012, Volume: 66, Issue:1

    Topics: Animals; Carrageenan; Chemical Fractionation; Chromatography, High Pressure Liquid; Inflammation; Intestinal Absorption; Intestinal Mucosa; Intestines; Liquid-Liquid Extraction; Male; Mice; Models, Biological; Naphthoquinones; Permeability; Plant Extracts; Plumbaginaceae; Polyethylene Glycols; Rats; Toxicity Tests, Acute; Water

2012
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherape
    The Journal of biological chemistry, 2006, Jun-23, Volume: 281, Issue:25

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cytokines; Dithiothreitol; Enzyme Activation; Humans; I-kappa B Proteins; Inflammation; Models, Chemical; Naphthoquinones; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; U937 Cells

2006