plumbagin has been researched along with Carcinoma, Hepatocellular in 10 studies
*Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, GH; Li, SY; Lin, CH; Shen, CC; Sun, CM; Syu, WJ | 1 |
| Bi, S; Chu, D; Guo, J; Guo, T; Han, S; Liao, A; Song, L; Song, X; Sun, D; Wang, L; Yu, Z; Zou, Y | 1 |
| Chen, X; Huang, Q; Jiang, B; Liu, J; Qi, L; Tang, D; Xue, Q; Yan, D; Yao, L | 1 |
| Jin, L; Liang, L; Liu, H; Liu, S; Wei, Y; Zhang, W | 1 |
| Chen, Y; Lin, Y; Lv, B; Ma, J; Peng, Y; Wang, S; Wei, Y; Xie, J; Zhang, Y; Zhong, J | 1 |
| Chen, W; Huang, D; Huo, L; Li, J; Lin, Y; Wei, J; Wei, Y; Zhao, C; Zhong, J | 1 |
| Chen, A; Jiang, Z; Liu, D; Liu, M; Lu, J; Wang, X; Ye, X; Zhou, X | 1 |
| Chen, W; Chen, Y; Lin, Y; Lv, B; Ma, J; Peng, Y; Wang, S; Wei, Y; Yuan, X | 1 |
| Li, R; Su, M; Wu, K; Zhou, R | 1 |
| Chen, Y; Li, J; Liu, X; Ma, J; Wei, Y; Yang, Q; Zhang, Y; Zhao, C; Zhao, T; Zhong, J | 1 |
10 other study(ies) available for plumbagin and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Antimicrobial activities of naphthazarins from Arnebia euchroma.
Topics: Anti-Bacterial Agents; Boraginaceae; Carcinoma, Hepatocellular; China; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; Enterococcus faecalis; Female; HeLa Cells; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plant Bark; Plants, Medicinal; Staphylococcus aureus; Stereoisomerism; Tumor Cells, Cultured; Vancomycin | 2002 |
Nano co-delivery of Plumbagin and Dihydrotanshinone I reverses immunosuppressive TME of liver cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Furans; Lactic Acid; Liver Neoplasms; Mice; Nanoparticles; Naphthoquinones; Phenanthrenes; Quinones; Tumor Microenvironment | 2022 |
Plumbagin is a novel GPX4 protein degrader that induces apoptosis in hepatocellular carcinoma cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Mitochondrial Proteins; Thiolester Hydrolases; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases | 2023 |
Plumbagin Exhibits Genotoxicity and Induces G2/M Cell Cycle Arrest via ROS-Mediated Oxidative Stress and Activation of ATM-p53 Signaling Pathway in Hepatocellular Cells.
Topics: Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Cycle Proteins; Checkpoint Kinase 2; DNA Damage; Humans; Liver Neoplasms; M Cells; Naphthoquinones; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2023 |
Plumbagin promotes human hepatoma SMMC-7721 cell apoptosis via caspase-3/vimentin signal-mediated EMT.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proliferation; Epithelial-Mesenchymal Transition; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Signal Transduction; Vimentin | 2019 |
Plumbagin Restrains Hepatocellular Carcinoma Angiogenesis by Stromal Cell-Derived Factor (SDF-1)/CXCR4-CXCR7 Axis.
Topics: Angiogenesis Inhibitors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-8; Liver; Liver Neoplasms; Naphthoquinones; Neoplasm Invasiveness; Neovascularization, Pathologic; Receptors, CXCR; Receptors, CXCR4; Signal Transduction; Stromal Cells; Vascular Endothelial Growth Factor A | 2019 |
Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme.
Topics: Animals; Antineoplastic Agents; Biological Products; Carcinoma, Hepatocellular; Cell Proliferation; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Hepatocytes; Humans; Kinetics; Liver Neoplasms; Male; Microsomes, Liver; Molecular Docking Simulation; Naphthoquinones; Rats, Sprague-Dawley | 2018 |
Plumbagin induces autophagy and apoptosis of SMMC-7721 cells in vitro and in vivo.
Topics: Animals; Apoptosis; Autophagic Cell Death; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Xenograft Model Antitumor Assays | 2019 |
Bioinformatic and experimental data decipher the pharmacological targets and mechanisms of plumbagin against hepatocellular carcinoma.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Computational Biology; Cyclin D1; Female; Hep G2 Cells; Humans; Liver Neoplasms; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Naphthoquinones; Proto-Oncogene Proteins c-raf; Tumor Suppressor Protein p53 | 2019 |
Plumbagin restrains hepatocellular carcinoma angiogenesis by suppressing the migration and invasion of tumor-derived vascular endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Neoplasm Invasiveness; Neovascularization, Pathologic; Signal Transduction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2017 |