plumbagin has been researched along with Cancer of Prostate in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Baron, VT; Borgström, P; Chrastina, A; Welsh, J | 1 |
| Che, YY; Shi, X; Song, YY; Yuan, Y | 1 |
| Bian, G; Chi, CL; Guo, FJ; Tian, JY; Wang, XQ; Xing, D | 1 |
| Ju, W; Li, W; Li, Z; Pan, M; Xiao, Y; Xing, Y; Yang, J; Zhang, X; Zhao, J | 1 |
| Abedinpour, P; Baron, VT; Borgström, P; Chrastina, A; Pelayo, J; Rondeau, G; Welsh, J | 1 |
| Chen, W; Huang, H; Pan, Y; Xia, Y; Xie, H; Zheng, K | 1 |
| Abedinpour, P; Borgstrom, P; Chrastina, A; Pelayo, J; Rondeau, G; Welsh, J | 1 |
| Abedinpour, P; Baron, VT; Borgström, P; Chrastina, A; Rondeau, G; Welsh, J | 1 |
| He, ZX; Mao, ZF; Qiu, JX; Yang, L; Zhang, X; Zhao, RJ; Zhou, SF; Zhou, ZW | 1 |
| Fischer, JW; Hafeez, BB; Meske, L; Mustafa, A; Sheikhani, MO; Singh, A; Verma, AK; Zhong, W | 1 |
| Kamath, RC; Lakshmanan, VK; Nair, HA; Nair, SV; Snima, KS | 1 |
| Chow, K; He, ZX; Li, XX; Pan, ST; Qiu, JX; Tan, J; Wang, D; Yang, T; Yang, Y; Zhang, X; Zhou, Q; Zhou, SF; Zhou, ZW | 1 |
| Adam, V; Babula, P; Balvan, J; Gumulec, J; Kizek, R; Krizova, A; Masarik, M; Raudenska, M; Stepka, P | 1 |
| Nadhan, R; Nair, RS; Reshma, RS; Satheesh Kumar, S; Somasundaram, V; Sreelatha, KH; Srinivas, P | 1 |
| Aziz, MH; Dreckschmidt, NE; Verma, AK | 1 |
| Fischer, JW; Hafeez, BB; Mustafa, A; Verma, AK; Witkowsky, O; Zhong, W | 1 |
| Cai, W; Fischer, JW; Hafeez, BB; Havighurst, T; Hong, H; Kim, K; Meske, L; Mustafa, A; Shi, X; Verma, AK; Zhong, W | 1 |
| Powolny, AA; Singh, SV | 1 |
18 other study(ies) available for plumbagin and Cancer of Prostate
| Article | Year |
|---|---|
Propylene Glycol Caprylate-Based Nanoemulsion Formulation of Plumbagin: Development and Characterization of Anticancer Activity.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Emulsions; Male; Mice; Nanoparticles; Naphthoquinones; Propylene Glycol; Prostatic Neoplasms | 2022 |
Improved drug delivery and anti-tumor efficacy of combinatorial liposomal formulation of genistein and plumbagin by targeting Glut1 and Akt3 proteins in mice bearing prostate tumor.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Drug Screening Assays, Antitumor; Genistein; Glucose Transporter Type 1; Humans; Liposomes; Male; Mice; Naphthoquinones; Neoplasms, Experimental; Particle Size; PC-3 Cells; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Surface Properties; Wound Healing | 2020 |
PSMA conjugated combinatorial liposomal formulation encapsulating genistein and plumbagin to induce apoptosis in prostate cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Genistein; Glutamate Carboxypeptidase II; Humans; Liposomes; Male; Naphthoquinones; Prostatic Neoplasms | 2021 |
Plumbagin-loaded aptamer-targeted poly D,L-lactic-co-glycolic acid-b-polyethylene glycol nanoparticles for prostate cancer therapy.
Topics: Antigens, Surface; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Glutamate Carboxypeptidase II; Humans; Male; Nanoparticles; Naphthoquinones; Particle Size; Prostatic Neoplasms | 2017 |
Plumbagin improves the efficacy of androgen deprivation therapy in prostate cancer: A pre-clinical study.
Topics: Androgen Receptor Antagonists; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Naphthoquinones; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Toxicity Tests; Treatment Outcome; Tumor Burden | 2017 |
Plumbagin Triggers ER Stress-Mediated Apoptosis in Prostate Cancer Cells via Induction of ROS.
Topics: Acetylcysteine; Activating Transcription Factor 4; Animals; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; eIF-2 Kinase; Endoplasmic Reticulum Stress; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Naphthoquinones; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; Transcription Factor CHOP; Transplantation, Heterologous | 2018 |
Differential gene expression induced by anti-cancer agent plumbagin is mediated by androgen receptor in prostate cancer cells.
Topics: Androgens; Animals; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Male; Mice; Naphthoquinones; Prostate; Prostatic Neoplasms; Receptors, Androgen; Testis; Transcriptome | 2018 |
Plumbagin-Loaded Nanoemulsion Drug Delivery Formulation and Evaluation of Antiproliferative Effect on Prostate Cancer Cells.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Liberation; Emulsions; Male; Mice; Nanoparticles; Naphthoquinones; Particle Size; Prostatic Neoplasms; Surface-Active Agents | 2018 |
Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Binding Sites; Biomarkers, Tumor; Blotting, Western; Cell Cycle; Cell Line, Tumor; Computational Biology; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Humans; Male; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Neoplasm Proteins; Prostatic Neoplasms; Protein Conformation; Protein Interaction Maps; Proteomics; Reproducibility of Results; Signal Transduction; Structure-Activity Relationship; Time Factors | 2015 |
Plumbagin Inhibits Prostate Carcinogenesis in Intact and Castrated PTEN Knockout Mice via Targeting PKCε, Stat3, and Epithelial-to-Mesenchymal Transition Markers.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Carcinogenesis; Epithelial-Mesenchymal Transition; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthoquinones; Orchiectomy; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Protein Kinase C-epsilon; PTEN Phosphohydrolase; Signal Transduction; STAT3 Transcription Factor | 2015 |
Plumbagin Nanoparticles Induce Dose and pH Dependent Toxicity on Prostate Cancer Cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Male; Mice; Nanoparticles; Naphthoquinones; NIH 3T3 Cells; Particle Size; Plant Extracts; Plumbaginaceae; Prostatic Neoplasms; Time Factors | 2015 |
Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.
Topics: Apoptosis; Autophagy; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Mitochondria; Molecular Structure; Naphthoquinones; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirtuin 1; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2015 |
Oxidative Stress Resistance in Metastatic Prostate Cancer: Renewal by Self-Eating.
Topics: Autophagy; Cell Communication; Cell Line, Tumor; Cell Self Renewal; Cell Size; Cell Survival; Endoplasmic Reticulum; Entosis; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Male; Mitophagy; Naphthoquinones; Neoplasm Metastasis; Oxidative Stress; Principal Component Analysis; Prostatic Neoplasms; Reactive Oxygen Species; Time-Lapse Imaging | 2015 |
Plumbagin, a naphthaquinone derivative induces apoptosis in BRCA 1/2 defective castrate resistant prostate cancer cells as well as prostate cancer stem-like cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; BRCA1 Protein; BRCA2 Protein; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Naphthoquinones; Neoplastic Stem Cells; Prostate; Prostatic Neoplasms | 2016 |
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer.
Topics: Animals; Apoptosis; Base Sequence; Cell Division; DNA Primers; Electrophoretic Mobility Shift Assay; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Naphthoquinones; Neoplasm Invasiveness; Plants, Medicinal; Prostatic Neoplasms | 2008 |
Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKCε, Stat3 and neuroendocrine markers.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antigens, Polyomavirus Transforming; Chromogranin A; Disease Models, Animal; Male; Mice; Mice, Transgenic; Naphthoquinones; Phosphorylation; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Protein Kinase C-epsilon; STAT3 Transcription Factor; Synaptophysin | 2012 |
Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Nude; Naphthoquinones; Neoplasm Metastasis; Nitric Oxide Synthase Type II; Plumbaginaceae; Prostate; Prostatic Neoplasms; Protein Kinase C; STAT3 Transcription Factor | 2013 |
Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Male; Naphthoquinones; Oxidation-Reduction; Peroxidases; Prostatic Neoplasms; Reactive Oxygen Species; Superoxide Dismutase | 2008 |